IMP
Process View
negative regulation of cell adhesion involved in substrate bound cell migration
The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cell adhesion involved in substrate bound cell migration"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Atp5a1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 | 0.636 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.562 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.453 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.349 | ||
| Cd247 | CD247 antigen | 0.307 | ||
| Lat | linker for activation of T cells | 0.225 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.185 | ||
| Tcra | T-cell receptor alpha chain | 0.151 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.108 | ||
| B2m | beta-2 microglobulin | 0.108 | ||
| Fyn | Fyn proto-oncogene | 0.087 | ||
| Tnf | tumor necrosis factor | 0.076 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.052 | ||
| Foxn1 | forkhead box N1 | 0.047 | ||
| Lyz2 | lysozyme 2 | 0.046 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.044 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.044 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.043 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.033 | Mouse | |
| Foxp3 | forkhead box P3 | 0.030 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.027 | ||
| Immt | inner membrane protein, mitochondrial | 0.026 | ||
| Vav1 | vav 1 oncogene | 0.025 | ||
| Ifng | interferon gamma | 0.023 | ||
| Prrx2 | paired related homeobox 2 | 0.022 | ||
| Efna2 | ephrin A2 | 0.019 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.019 | ||
| Kcnh3 | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 0.019 | ||
| Ltb | lymphotoxin B | 0.018 | ||
| Uqcrfs1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 0.017 | ||
| Il2 | interleukin 2 | 0.017 | ||
| H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.016 | ||
| Pkm2 | pyruvate kinase, muscle | 0.015 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.014 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.014 | ||
| Ubtd1 | ubiquitin domain containing 1 | 0.014 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.014 | ||
| Was | Wiskott-Aldrich syndrome homolog (human) | 0.013 | ||
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.013 | ||
| Rag2 | recombination activating gene 2 | 0.013 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.012 | ||
| Cd53 | CD53 antigen | 0.012 | ||
| Col3a1 | collagen, type III, alpha 1 | 0.012 | ||
| Diras1 | DIRAS family, GTP-binding RAS-like 1 | 0.012 | ||
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.012 | ||
| Il7r | interleukin 7 receptor | 0.012 | ||
| Zbtb7c | zinc finger and BTB domain containing 7C | 0.012 | ||
| Nrtn | neurturin | 0.011 | ||
| Jak3 | Janus kinase 3 | 0.011 | ||
| Cd44 | CD44 antigen | 0.011 | ||
| B3gat1 | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | 0.011 | ||
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.011 | ||
| Plek | pleckstrin | 0.011 | ||
| Gapdh | glyceraldehyde-3-phosphate dehydrogenase | 0.010 | ||
| Cd19 | CD19 antigen | 0.010 | ||
| Hic1 | hypermethylated in cancer 1 | 0.010 | ||
| Cs | citrate synthase | 0.010 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.010 | ||
| Jak2 | Janus kinase 2 | 0.010 | ||
| Hoxa2 | homeobox A2 | 0.010 |