|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.967
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.951
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.906
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.818
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.804
|
Mouse |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.803
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.797
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.788
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.773
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.771
|
Mouse |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.725
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.721
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.712
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.710
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.707
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.706
|
Mouse |
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.706
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.697
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.687
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.683
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.678
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.651
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.642
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.624
|
Mouse |
|
|
response to protozoan
|
GO:0001562 |
28 |
0.617
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.586
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.555
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.549
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.541
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.534
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.529
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.521
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.510
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.459
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.444
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.442
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.420
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.417
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.401
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.396
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.395
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.381
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.381
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.379
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.378
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.375
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.361
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.356
|
Mouse |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.352
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.352
|
Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.346
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.345
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.338
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.334
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.329
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.329
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.321
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.320
|
Mouse |
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.317
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.316
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.310
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.306
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.303
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.302
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.292
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.281
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.279
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.278
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.273
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.273
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.272
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.266
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.265
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.264
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.262
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.260
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.260
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.259
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.258
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.253
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.253
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.253
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.247
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.241
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.241
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.240
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.236
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.235
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.230
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.224
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.221
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.217
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.215
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.213
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.212
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.212
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.207
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.207
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.202
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.202
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.201
|
Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.201
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.199
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.198
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.197
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.196
|
Mouse |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.194
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.192
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.192
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.191
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.190
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.190
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.187
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.186
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.186
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.184
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.183
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.177
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.177
|
Mouse |
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.176
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.175
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.173
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.172
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.169
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.168
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.167
|
Mouse |
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.167
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.165
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.164
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.164
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.162
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.162
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.161
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.159
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.158
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.158
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.158
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.155
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.155
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.155
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.154
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.153
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
141 |
0.153
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.152
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.150
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.149
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.149
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.147
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.145
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.145
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.143
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.143
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.143
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.142
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.141
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.140
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.139
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.139
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.139
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.139
|
Mouse |
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.137
|
Mouse |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.137
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.135
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.135
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.135
|
Mouse |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.134
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.134
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.134
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.133
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.133
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.133
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.133
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.132
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.131
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.130
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.130
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.128
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.128
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.128
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.127
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.126
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.125
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.125
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.124
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.124
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.124
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.123
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.121
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.121
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.119
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.119
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.119
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.119
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.118
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.118
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.117
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.117
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.115
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.115
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.113
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.111
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.111
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.111
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.110
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.109
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.109
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.109
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.109
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.108
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.107
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.105
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.104
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.104
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.104
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.103
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.102
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.101
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.101
|
Mouse |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.100
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.100
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.099
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.099
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.097
|
Mouse |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.097
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.097
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.097
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.096
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.095
|
Mouse |
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.093
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.093
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.093
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.092
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.092
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.090
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.089
|
|
|
|
establishment of t cell polarity
|
GO:0001768 |
2 |
0.089
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.088
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.088
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.088
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.088
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.088
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.087
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.086
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.086
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.086
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.086
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.085
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.085
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.084
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.084
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.084
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.084
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.083
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.082
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.081
|
|
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.079
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.078
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.078
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.077
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.077
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.077
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.076
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.076
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.075
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.075
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
168 |
0.075
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.075
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.074
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.073
|
Mouse |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.072
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.072
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.072
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.072
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.071
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.071
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.071
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.071
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.070
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.070
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.070
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.070
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.069
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.068
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.067
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.067
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.067
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.067
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.066
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.066
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.066
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.066
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.065
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.065
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.065
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.064
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.064
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.064
|
Mouse |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.064
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.063
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.063
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.063
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.062
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.062
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.062
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.062
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.061
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.061
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.061
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.061
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.061
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.061
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.060
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.060
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.060
|
Mouse |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.059
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.059
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.059
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.059
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.059
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.059
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.059
|
Mouse |
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.059
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.058
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.058
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.058
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.058
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.057
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.056
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.055
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.055
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.055
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.055
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.053
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.053
|
Mouse |
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.053
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.053
|
Mouse |
|
|
t helper 17 type immune response
|
GO:0072538 |
9 |
0.052
|
Mouse |
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.052
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.052
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.051
|
Mouse |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.051
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.051
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.050
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.050
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.050
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.050
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.050
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.049
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.049
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.049
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.049
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.049
|
Mouse |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.049
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.048
|
Mouse |
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.048
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.048
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.047
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.047
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.047
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.047
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.047
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.046
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.046
|
Mouse |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.046
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.046
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.046
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.046
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.046
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.046
|
Mouse |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.046
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.045
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.045
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.045
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.045
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.045
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.044
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.044
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.044
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.044
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.044
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.044
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.044
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.044
|
Mouse |
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.043
|
Mouse |
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.043
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.043
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.043
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.042
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.042
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.042
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.042
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.042
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.041
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.041
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.041
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.041
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.041
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.041
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.040
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.040
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.040
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.040
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.040
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.040
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.040
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.040
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.039
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.039
|
Mouse |
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.039
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.039
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.039
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.039
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.038
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.038
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.038
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.038
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.038
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.038
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.038
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.037
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.037
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.037
|
Mouse |
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.037
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.037
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.037
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.036
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.036
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.036
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.036
|
Mouse |
|
|
protein acylation
|
GO:0043543 |
64 |
0.036
|
Mouse |
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.036
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.036
|
Mouse |
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.035
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.035
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.035
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.035
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.035
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.035
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
5 |
0.035
|
Mouse |
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.035
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.035
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.034
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.034
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.034
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.034
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.034
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.033
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.033
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.033
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.033
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.033
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.033
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.033
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.033
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.032
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.032
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.032
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.032
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.032
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.032
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.032
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.032
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.032
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.031
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.031
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.031
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.031
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.031
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.031
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.031
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.030
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.030
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.030
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.030
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.030
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.030
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.030
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.030
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.030
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.030
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.029
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.029
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.029
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.029
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.029
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.029
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.029
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.029
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.029
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.029
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.029
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.029
|
Mouse |
|
|
dendrite development
|
GO:0016358 |
115 |
0.029
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.029
|
|
