|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
1.000
|
Human |
|
|
immune effector process
|
GO:0002252 |
321 |
0.991
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.971
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.940
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.930
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.910
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.902
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.874
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.854
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.805
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.781
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.778
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.776
|
Human |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.771
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.768
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.744
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.724
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.695
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.673
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.656
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.652
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.631
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.630
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.628
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.625
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.625
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.612
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.585
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.573
|
Human |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.571
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.558
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.536
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.533
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.530
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.526
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.518
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.511
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.499
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.499
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.498
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.497
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.489
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.489
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.488
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.485
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.481
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.459
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.453
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.438
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.424
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.420
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.413
|
Mouse Fly |
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.409
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.406
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.395
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.392
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.391
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.388
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.374
|
Worm |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.363
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.360
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.358
|
Mouse Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.354
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.353
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.342
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.342
|
Mouse Worm |
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.336
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.335
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.324
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.324
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.321
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.319
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.315
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.315
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.312
|
|
|
|
integrin activation
|
GO:0033622 |
8 |
0.304
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.303
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.300
|
Mouse Fly |
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.292
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.291
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.290
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.278
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.271
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.269
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.267
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.260
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.257
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.256
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.256
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.244
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.238
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.237
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.237
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.235
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.233
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.233
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.232
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.231
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.230
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.230
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.228
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.224
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.223
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.223
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.222
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.222
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.221
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.220
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.218
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.217
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.216
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.216
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.214
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.211
|
Fly |
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.210
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.209
|
|
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.205
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.205
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.202
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.201
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.201
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.196
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.195
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.189
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.188
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.183
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.182
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.181
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.179
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.178
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.177
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.176
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.174
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.173
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.169
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.168
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.167
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.166
|
Mouse |
|
|
hemostasis
|
GO:0007599 |
78 |
0.164
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.164
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.163
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.159
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.159
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.157
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.156
|
Fly |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.156
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.156
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.156
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.155
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.155
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.152
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.152
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.148
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.148
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.148
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.146
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.146
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.145
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.145
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.144
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.143
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.142
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.141
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.139
|
Human |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.137
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.136
|
Worm |
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.135
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.134
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.134
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.133
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.133
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.128
|
Fly |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.126
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.126
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.125
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.124
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.123
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.123
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.122
|
Mouse |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.122
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.120
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.120
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.118
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.118
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.117
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.116
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.116
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.115
|
Mouse |
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.114
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.114
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.114
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.113
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.112
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.111
|
Fly |
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.110
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.109
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.108
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.108
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.106
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.106
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.106
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.105
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.104
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.104
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.104
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.104
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.104
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.104
|
Fly |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.104
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.103
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.103
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.101
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.100
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.099
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.098
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.098
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.098
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.097
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.096
|
Mouse |
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.095
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.095
|
Mouse Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.095
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.094
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.094
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.094
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.094
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.093
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.092
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.091
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.091
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.091
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.090
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.090
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.089
|
|
|
|
regulation of integrin activation
|
GO:0033623 |
4 |
0.089
|
|
|
|
face morphogenesis
|
GO:0060325 |
29 |
0.089
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.089
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.088
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.087
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.087
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.086
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.086
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.085
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.085
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.085
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.084
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.084
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.084
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.083
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.082
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.082
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.081
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.081
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.081
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.080
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.079
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.078
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.078
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.077
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.076
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.076
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.076
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.076
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.075
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.075
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.074
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.074
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.074
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.073
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.071
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.071
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.071
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.071
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.071
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.070
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.070
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.070
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.070
|
Mouse |
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.069
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.069
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.069
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.069
|
Mouse |
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.069
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.069
|
Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.068
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.068
|
Fly |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.068
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.068
|
|
|
|
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0007157 |
20 |
0.068
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.068
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.068
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.068
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.067
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.067
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.066
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.066
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.066
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.066
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.065
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.064
|
Mouse |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.063
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.063
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.062
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
3 |
0.062
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.062
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.062
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.062
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.061
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.061
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.061
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.061
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.061
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.061
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.061
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.060
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.060
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.060
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.060
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.060
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.060
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.059
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.059
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.059
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.058
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.058
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.058
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.057
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.057
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.057
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.057
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.056
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.056
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.056
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.056
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.056
|
Mouse |
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.055
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.055
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.055
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.055
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.054
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.054
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.054
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.054
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.053
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.053
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.053
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.052
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.052
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.052
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.052
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.052
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.052
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.051
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.051
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.051
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.051
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.050
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.050
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.050
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.049
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.049
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.048
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.048
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.047
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.047
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.047
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.047
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.047
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.046
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.046
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.046
|
|
|
|
leukocyte tethering or rolling
|
GO:0050901 |
3 |
0.046
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.046
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.046
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.046
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.045
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.045
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.045
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.045
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.045
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.045
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.045
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.044
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.044
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.044
|
Fly |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.044
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.044
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.043
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.043
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.043
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.043
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.043
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.043
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.042
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.042
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.042
|
Human Fly |
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.042
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.042
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.042
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.041
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.041
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.041
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.041
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.040
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.040
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.040
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.040
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.040
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.039
|
Fly |
|
|
leukocyte aggregation
|
GO:0070486 |
1 |
0.039
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.039
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.039
|
Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.039
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.039
|
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.038
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.038
|
Fly |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.038
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.038
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.038
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.038
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.038
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.038
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.038
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.038
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.038
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.038
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.038
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.038
|
Mouse Fly |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.037
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.037
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.037
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.037
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.037
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.037
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.037
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.036
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.036
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.036
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.036
|
|
|
|
cell communication by chemical coupling
|
GO:0010643 |
2 |
0.036
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.036
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.036
|
|
|
|
substrate dependent cell migration cell extension
|
GO:0006930 |
4 |
0.036
|
Fly |
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.035
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.035
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.035
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.035
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.035
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
5 |
0.035
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.035
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.035
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.034
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.034
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.034
|
|
|
|
face development
|
GO:0060324 |
38 |
0.034
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.034
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.033
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.033
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.033
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.033
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.033
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.032
|
Human Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.032
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.032
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.032
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.032
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.032
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.032
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.031
|
Mouse |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.031
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.031
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.031
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.031
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.031
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.031
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.031
|
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.031
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.031
|
Human Mouse Fly |
|
|
amide transport
|
GO:0042886 |
138 |
0.031
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.030
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.030
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.030
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.030
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.030
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.030
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.030
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.030
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.030
|
|
