Mus musculus

221 known processes

Lrp8

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

(Aliases: Lr8b,ApoER2,4932703M08Rik,AI848122,AA921429)

Lrp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of clathrin mediated endocytosis GO:2000369 4 0.994
layer formation in cerebral cortex GO:0021819 13 0.961
positive regulation of dendrite development GO:1900006 21 0.660
cerebral cortex radial glia guided migration GO:0021801 17 0.608
cerebral cortex radially oriented cell migration GO:0021799 31 0.601
motor neuron migration GO:0097475 4 0.584
amine metabolic process GO:0009308 45 0.572
Mouse
spinal cord development GO:0021510 81 0.557
regulation of cellular amino acid metabolic process GO:0006521 5 0.507
positive regulation of neuron projection development GO:0010976 79 0.433
cellular amino acid metabolic process GO:0006520 103 0.426
cerebral cortex development GO:0021987 86 0.412
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.408
regulation of protein tyrosine kinase activity GO:0061097 17 0.405
glutamate receptor signaling pathway GO:0007215 35 0.385
dendritic spine development GO:0060996 30 0.376
clathrin coat assembly GO:0048268 2 0.374
forebrain development GO:0030900 302 0.369
positive regulation of creb transcription factor activity GO:0032793 4 0.341
dendritic spine morphogenesis GO:0060997 22 0.335
regulation of cellular ketone metabolic process GO:0010565 66 0.323
dendrite development GO:0016358 115 0.321
synaptic transmission GO:0007268 329 0.314
regulation of dendritic spine morphogenesis GO:0061001 17 0.305
forebrain cell migration GO:0021885 58 0.291
peptidyl tyrosine phosphorylation GO:0018108 143 0.285
regulation of plasma lipoprotein particle levels GO:0097006 23 0.281
Mouse
telencephalon development GO:0021537 186 0.276
regulation of glutamate receptor signaling pathway GO:1900449 16 0.273
regulation of cellular amine metabolic process GO:0033238 20 0.269
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.267
multicellular organismal response to stress GO:0033555 62 0.252
regulation of neuron projection development GO:0010975 169 0.240
midgut development GO:0007494 4 0.238
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.236
regulation of protein kinase activity GO:0045859 232 0.229
positive regulation of dendritic spine development GO:0060999 12 0.221
cerebellum morphogenesis GO:0021587 42 0.220
regulation of kinase activity GO:0043549 249 0.215
lateral motor column neuron migration GO:0097477 3 0.215
microtubule based movement GO:0007018 84 0.211
hindbrain radial glia guided cell migration GO:0021932 12 0.204
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.203
telencephalon cell migration GO:0022029 55 0.202
regulation of neuron differentiation GO:0045664 281 0.202
small gtpase mediated signal transduction GO:0007264 97 0.202
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.202
sterol transmembrane transport GO:0035382 2 0.192
Mouse
limbic system development GO:0021761 72 0.188
regulation of transferase activity GO:0051338 263 0.186
cerebral cortex cell migration GO:0021795 44 0.182
organic hydroxy compound metabolic process GO:1901615 203 0.181
Mouse
cellular ketone metabolic process GO:0042180 84 0.174
positive regulation of neuron differentiation GO:0045666 141 0.172
positive regulation of dendritic spine morphogenesis GO:0061003 8 0.172
axonogenesis GO:0007409 274 0.171
macromolecule catabolic process GO:0009057 281 0.171
Mouse
transmembrane transport GO:0055085 412 0.170
Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.163
triglyceride biosynthetic process GO:0019432 17 0.162
Mouse
peptidyl amino acid modification GO:0018193 336 0.160
metencephalon development GO:0022037 89 0.157
dendritic spine organization GO:0097061 26 0.150
positive regulation of cell development GO:0010720 237 0.150
positive regulation of clathrin mediated endocytosis GO:2000370 1 0.147
regulation of cell projection organization GO:0031344 206 0.145
cellular response to lipid GO:0071396 145 0.142
camera type eye development GO:0043010 266 0.141
organelle localization GO:0051640 179 0.141
positive regulation of dna templated transcription elongation GO:0032786 2 0.139
negative regulation of intracellular signal transduction GO:1902532 167 0.138
synapse organization GO:0050808 125 0.137
cellular lipid metabolic process GO:0044255 323 0.136
Mouse
positive regulation of kinase activity GO:0033674 155 0.135
establishment of organelle localization GO:0051656 122 0.132
regionalization GO:0003002 337 0.129
developmental maturation GO:0021700 193 0.124
alcohol metabolic process GO:0006066 116 0.123
Mouse
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.122
Mouse
regulation of cellular response to stress GO:0080135 159 0.119
regulation of organelle organization GO:0033043 289 0.116
molting cycle GO:0042303 90 0.115
negative regulation of molecular function GO:0044092 258 0.115
cellular amine metabolic process GO:0044106 44 0.110
Mouse
cilium assembly GO:0042384 81 0.106
golgi localization GO:0051645 4 0.106
organonitrogen compound catabolic process GO:1901565 264 0.106
Mouse
establishment of vesicle localization GO:0051650 81 0.106
organic anion transport GO:0015711 137 0.103
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.102
regulation of receptor activity GO:0010469 41 0.101
anion transport GO:0006820 177 0.100
Mouse
lymphocyte differentiation GO:0030098 242 0.100
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.100
positive regulation of protein tyrosine kinase activity GO:0061098 10 0.099
pallium development GO:0021543 120 0.098
glycerolipid metabolic process GO:0046486 122 0.096
Mouse
regulation of ion transport GO:0043269 215 0.096
learning GO:0007612 98 0.095
positive regulation of protein modification process GO:0031401 299 0.095
membrane organization GO:0061024 245 0.095
regulation of apoptotic signaling pathway GO:2001233 197 0.092
regulation of membrane potential GO:0042391 192 0.092
clathrin mediated endocytosis GO:0072583 7 0.092
hindbrain morphogenesis GO:0021575 46 0.092
positive regulation of tor signaling GO:0032008 3 0.090
ion transmembrane transport GO:0034220 361 0.088
low density lipoprotein particle clearance GO:0034383 8 0.087
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.086
regulation of jnk cascade GO:0046328 62 0.086
positive regulation of protein phosphorylation GO:0001934 242 0.084
response to acid chemical GO:0001101 111 0.084
axon guidance GO:0007411 141 0.084
response to corticosterone GO:0051412 1 0.084
response to molecule of bacterial origin GO:0002237 143 0.082
regulation of cytoskeleton organization GO:0051493 122 0.082
protein catabolic process GO:0030163 221 0.082
Mouse
gliogenesis GO:0042063 141 0.081
ras protein signal transduction GO:0007265 77 0.080
regulation of ion transmembrane transporter activity GO:0032412 54 0.079
positive regulation of nervous system development GO:0051962 221 0.079
regulation of synaptic transmission glutamatergic GO:0051966 19 0.078
stress activated protein kinase signaling cascade GO:0031098 81 0.078
stress activated mapk cascade GO:0051403 80 0.077
cellular response to hormone stimulus GO:0032870 150 0.076
regulation of stress activated mapk cascade GO:0032872 69 0.076
jak stat cascade GO:0007259 42 0.075
regulation of cell cycle GO:0051726 281 0.074
cerebellum development GO:0021549 77 0.074
actin cytoskeleton organization GO:0030036 220 0.074
organophosphate ester transport GO:0015748 28 0.074
Mouse
regulation of integrin mediated signaling pathway GO:2001044 8 0.074
negative regulation of cell projection organization GO:0031345 56 0.073
endocytosis GO:0006897 168 0.073
Human Mouse
sensory perception GO:0007600 245 0.073
spinal cord motor neuron migration GO:0097476 4 0.073
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.073
modification dependent macromolecule catabolic process GO:0043632 133 0.072
cellularization GO:0007349 1 0.072
cellular biogenic amine metabolic process GO:0006576 28 0.071
Mouse
negative regulation of nervous system development GO:0051961 156 0.071
positive regulation of cellular amine metabolic process GO:0033240 5 0.070
tube formation GO:0035148 140 0.069
jnk cascade GO:0007254 72 0.069
acylglycerol metabolic process GO:0006639 55 0.067
Mouse
anatomical structure homeostasis GO:0060249 145 0.067
vesicle organization GO:0016050 60 0.067
vesicle coating GO:0006901 2 0.067
hippocampus development GO:0021766 52 0.066
neural tube development GO:0021915 160 0.065
digestive tract development GO:0048565 190 0.065
vesicle localization GO:0051648 86 0.064
lipid catabolic process GO:0016042 69 0.062
Mouse
response to amino acid GO:0043200 37 0.062
mapk cascade GO:0000165 281 0.062
establishment of synaptic vesicle localization GO:0097480 57 0.062
cell cell adhesion GO:0098609 41 0.062
apoptotic signaling pathway GO:0097190 306 0.061
negative regulation of cellular protein metabolic process GO:0032269 247 0.061
peptidyl tyrosine modification GO:0018212 145 0.061
cellular protein catabolic process GO:0044257 155 0.061
negative regulation of apoptotic signaling pathway GO:2001234 104 0.060
cation transport GO:0006812 399 0.060
morphogenesis of embryonic epithelium GO:0016331 159 0.060
hindbrain development GO:0030902 128 0.059
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.059
cellular macromolecule catabolic process GO:0044265 206 0.059
synaptic vesicle transport GO:0048489 57 0.059
organelle assembly GO:0070925 177 0.058
regulation of protein localization GO:0032880 231 0.058
multicellular organismal homeostasis GO:0048871 164 0.058
lipid transport GO:0006869 98 0.058
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.058
intracellular protein transport GO:0006886 204 0.058
positive regulation of programmed cell death GO:0043068 218 0.057
angiogenesis GO:0001525 201 0.057
axon transport of mitochondrion GO:0019896 2 0.057
regulation of triglyceride biosynthetic process GO:0010866 10 0.057
Mouse
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.057
primary neural tube formation GO:0014020 95 0.057
sterol import GO:0035376 2 0.056
Mouse
nuclear division GO:0000280 158 0.056
cytoplasmic transport GO:0016482 234 0.056
blood vessel morphogenesis GO:0048514 285 0.056
regulation of cellular catabolic process GO:0031329 242 0.056
Mouse
regulation of hormone levels GO:0010817 211 0.055
cell adhesion GO:0007155 329 0.053
epithelial tube formation GO:0072175 130 0.053
multi organism behavior GO:0051705 62 0.053
protein localization to membrane GO:0072657 108 0.053
intraspecies interaction between organisms GO:0051703 21 0.052
positive regulation of cell migration GO:0030335 109 0.052
microtubule based transport GO:0010970 50 0.052
lipoprotein metabolic process GO:0042157 43 0.051
Mouse
response to transforming growth factor beta GO:0071559 88 0.051
epidermis development GO:0008544 187 0.051
positive regulation of transferase activity GO:0051347 167 0.050
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.050
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.050
regulation of secretion by cell GO:1903530 249 0.049
retina morphogenesis in camera type eye GO:0060042 45 0.049
regulation of phospholipid catabolic process GO:0060696 2 0.047
Mouse
lipid biosynthetic process GO:0008610 179 0.047
Mouse
regulation of transmembrane transport GO:0034762 128 0.047
response to extracellular stimulus GO:0009991 127 0.047
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.046
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.046
compound eye development GO:0048749 1 0.046
regulation of mapk cascade GO:0043408 248 0.046
nitrogen compound transport GO:0071705 271 0.044
cellular chemical homeostasis GO:0055082 215 0.044
cell substrate adhesion GO:0031589 130 0.043
regulation of tor signaling GO:0032006 17 0.043
substrate adhesion dependent cell spreading GO:0034446 30 0.043
skeletal system development GO:0001501 356 0.042
integrin mediated signaling pathway GO:0007229 27 0.042
membrane depolarization GO:0051899 64 0.042
regulation of protein serine threonine kinase activity GO:0071900 157 0.042
male gamete generation GO:0048232 285 0.042
positive regulation of mapk cascade GO:0043410 170 0.041
postsynaptic membrane organization GO:0001941 18 0.041
phospholipid metabolic process GO:0006644 87 0.041
Mouse
negative regulation of neuron projection development GO:0010977 50 0.041
response to lipopolysaccharide GO:0032496 128 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
regulation of ion transmembrane transport GO:0034765 119 0.040
regulation of ras protein signal transduction GO:0046578 114 0.040
protein targeting GO:0006605 143 0.040
synaptic transmission glutamatergic GO:0035249 36 0.040
cellular lipid catabolic process GO:0044242 52 0.040
Mouse
neuron migration GO:0001764 122 0.040
neuron projection guidance GO:0097485 141 0.039
cholesterol transport GO:0030301 38 0.039
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
retina development in camera type eye GO:0060041 119 0.038
establishment of tissue polarity GO:0007164 28 0.038
aromatic compound catabolic process GO:0019439 286 0.038
neuron neuron synaptic transmission GO:0007270 69 0.037
sensory organ morphogenesis GO:0090596 242 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.037
connective tissue development GO:0061448 179 0.037
cell migration in hindbrain GO:0021535 16 0.037
glycerolipid catabolic process GO:0046503 16 0.037
Mouse
mrna metabolic process GO:0016071 84 0.036
response to drug GO:0042493 75 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.036
cellular response to biotic stimulus GO:0071216 92 0.036
extrinsic apoptotic signaling pathway GO:0097191 126 0.036
response to organic cyclic compound GO:0014070 198 0.036
response to mineralocorticoid GO:0051385 1 0.036
rna processing GO:0006396 105 0.036
cellular response to molecule of bacterial origin GO:0071219 83 0.036
regulation of transporter activity GO:0032409 57 0.036
cellular response to organonitrogen compound GO:0071417 145 0.036
regulation of t cell activation GO:0050863 170 0.036
cardiac chamber morphogenesis GO:0003206 93 0.036
response to radiation GO:0009314 165 0.035
sterol transport GO:0015918 38 0.035
Mouse
protein modification by small protein conjugation GO:0032446 187 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
t cell differentiation GO:0030217 174 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
response to growth factor GO:0070848 198 0.035
response to peptide GO:1901652 136 0.035
positive regulation of cell motility GO:2000147 116 0.035
rho protein signal transduction GO:0007266 32 0.035
sterol homeostasis GO:0055092 45 0.034
Mouse
positive regulation of apoptotic process GO:0043065 217 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.034
regulation of lymphocyte activation GO:0051249 240 0.034
multi multicellular organism process GO:0044706 109 0.034
positive regulation of cytokine production GO:0001819 174 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.034
regulation of cell adhesion GO:0030155 154 0.033
regulation of proteolysis GO:0030162 164 0.033
neuron apoptotic process GO:0051402 142 0.033
embryonic organ morphogenesis GO:0048562 276 0.033
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.033
cytoskeleton dependent intracellular transport GO:0030705 50 0.033
cellular response to lipopolysaccharide GO:0071222 77 0.033
positive regulation of cell activation GO:0050867 158 0.032
positive regulation of growth GO:0045927 104 0.032
receptor recycling GO:0001881 11 0.032
transmission of nerve impulse GO:0019226 76 0.032
regulation of synaptic plasticity GO:0048167 87 0.032
skeletal system morphogenesis GO:0048705 203 0.032
cellular component assembly involved in morphogenesis GO:0010927 139 0.032
regulation of cytokine production GO:0001817 266 0.032
response to insulin GO:0032868 100 0.031
steroid metabolic process GO:0008202 119 0.031
Mouse
appendage development GO:0048736 166 0.031
mitotic cell cycle GO:0000278 195 0.031
negative regulation of immune system process GO:0002683 209 0.031
organic hydroxy compound transport GO:0015850 93 0.030
Mouse
regulation of map kinase activity GO:0043405 120 0.030
negative regulation of mapk cascade GO:0043409 65 0.030
glycoprotein metabolic process GO:0009100 116 0.030
microtubule based process GO:0007017 236 0.030
positive regulation of stress activated mapk cascade GO:0032874 48 0.030
gland development GO:0048732 330 0.029
regulation of defense response GO:0031347 233 0.029
neuron death GO:0070997 154 0.029
muscle tissue development GO:0060537 308 0.029
positive regulation of cellular catabolic process GO:0031331 148 0.029
memory GO:0007613 58 0.029
glial cell differentiation GO:0010001 131 0.029
neural tube formation GO:0001841 108 0.028
myeloid cell differentiation GO:0030099 233 0.028
positive regulation of jnk cascade GO:0046330 46 0.028
neural tube closure GO:0001843 90 0.028
cation homeostasis GO:0055080 212 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
wound healing GO:0042060 157 0.028
organelle fission GO:0048285 170 0.028
cilium morphogenesis GO:0060271 102 0.028
negative regulation of cell cycle GO:0045786 123 0.028
reactive oxygen species biosynthetic process GO:1903409 8 0.028
inflammatory response GO:0006954 244 0.028
cellular response to oxygen levels GO:0071453 20 0.028
sterol metabolic process GO:0016125 58 0.028
Mouse
nucleotide metabolic process GO:0009117 332 0.028
synapse maturation GO:0060074 14 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
t cell activation GO:0042110 289 0.027
synaptic vesicle recycling GO:0036465 19 0.027
response to oxygen levels GO:0070482 62 0.027
ventral spinal cord development GO:0021517 48 0.027
nuclear transport GO:0051169 139 0.027
organophosphate catabolic process GO:0046434 232 0.027
Mouse
regulation of jun kinase activity GO:0043506 40 0.027
regulation of inflammatory response GO:0050727 147 0.027
regulation of lipid metabolic process GO:0019216 118 0.027
Mouse
glycerophospholipid catabolic process GO:0046475 5 0.027
Mouse
leukocyte differentiation GO:0002521 342 0.027
positive regulation of cell cycle process GO:0090068 61 0.027
spinal cord patterning GO:0021511 25 0.026
negative regulation of transferase activity GO:0051348 85 0.026
regulation of establishment of planar polarity GO:0090175 28 0.026
synaptic vesicle localization GO:0097479 59 0.026
regulation of neuron migration GO:2001222 22 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
immune effector process GO:0002252 321 0.026
synapse assembly GO:0007416 56 0.026
response to peptide hormone GO:0043434 127 0.026
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.026
regulation of terminal button organization GO:2000331 1 0.025
cellular response to insulin stimulus GO:0032869 78 0.025
placenta development GO:0001890 140 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
regulation of receptor recycling GO:0001919 8 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
regulation of fat cell differentiation GO:0045598 81 0.025
establishment of planar polarity GO:0001736 28 0.025
cellular homeostasis GO:0019725 240 0.025
carbohydrate homeostasis GO:0033500 128 0.025
regulation of cellular component size GO:0032535 121 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
nucleoside catabolic process GO:0009164 206 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
cytokine production GO:0001816 319 0.025
homeostasis of number of cells GO:0048872 210 0.024
regulation of protein processing GO:0070613 96 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
acylglycerol biosynthetic process GO:0046463 18 0.024
Mouse
chemotaxis GO:0006935 247 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
chromatin organization GO:0006325 206 0.024
protein maturation GO:0051604 176 0.024
regulation of cell cycle process GO:0010564 160 0.024
heart morphogenesis GO:0003007 178 0.024
carbohydrate metabolic process GO:0005975 230 0.024
diencephalon development GO:0021536 63 0.024
wnt signaling pathway GO:0016055 188 0.024
histone modification GO:0016570 159 0.023
neutral lipid biosynthetic process GO:0046460 18 0.023
Mouse
cholesterol metabolic process GO:0008203 56 0.023
Mouse
actin filament organization GO:0007015 113 0.023
digestive system development GO:0055123 200 0.023
limb morphogenesis GO:0035108 149 0.023
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
urogenital system development GO:0001655 261 0.023
response to interleukin 1 GO:0070555 11 0.023
regulation of binding GO:0051098 111 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
peripheral nervous system development GO:0007422 53 0.023
cellular calcium ion homeostasis GO:0006874 119 0.023
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.023
cellular response to decreased oxygen levels GO:0036294 18 0.022
embryonic epithelial tube formation GO:0001838 130 0.022
dendrite self avoidance GO:0070593 2 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
cellular modified amino acid metabolic process GO:0006575 63 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
peptide hormone secretion GO:0030072 109 0.022
negative regulation of fat cell differentiation GO:0045599 36 0.022
positive regulation of cell death GO:0010942 224 0.022
anatomical structure maturation GO:0071695 49 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.022
phosphatidylinositol mediated signaling GO:0048015 41 0.022
single organism cell adhesion GO:0098602 156 0.022
b cell differentiation GO:0030183 78 0.022
germ cell development GO:0007281 185 0.022
regulation of secretion GO:0051046 274 0.022
regulation of actin filament based process GO:0032970 99 0.021
phenol containing compound metabolic process GO:0018958 60 0.021
exocytosis GO:0006887 121 0.021
lymphocyte proliferation GO:0046651 164 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
canonical wnt signaling pathway GO:0060070 130 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
regulation of protein maturation GO:1903317 96 0.021
multicellular organismal signaling GO:0035637 91 0.021
neurotransmitter transport GO:0006836 76 0.021
amino acid transport GO:0006865 61 0.021
visual perception GO:0007601 52 0.021
positive regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000969 3 0.021
protein processing GO:0016485 163 0.021
response to light stimulus GO:0009416 135 0.021
endomembrane system organization GO:0010256 147 0.021
striated muscle tissue development GO:0014706 293 0.021
hormone secretion GO:0046879 128 0.021
positive regulation of glutamate receptor signaling pathway GO:1900451 3 0.021
protein localization to synapse GO:0035418 11 0.021
regulation of lipid biosynthetic process GO:0046890 54 0.020
Mouse
eye photoreceptor cell development GO:0042462 31 0.020
sperm motility GO:0030317 47 0.020
regulation of lipid catabolic process GO:0050994 15 0.020
Mouse
positive regulation of mitotic cell cycle GO:0045931 41 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
b cell activation GO:0042113 161 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
defecation GO:0030421 1 0.020
regulation of response to wounding GO:1903034 189 0.020
cellular ion homeostasis GO:0006873 165 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.020
hair cycle GO:0042633 90 0.020
synaptic vesicle endocytosis GO:0048488 19 0.020
respiratory system development GO:0060541 190 0.020
receptor mediated endocytosis GO:0006898 51 0.020
Human Mouse
ear morphogenesis GO:0042471 118 0.020
regulation of actin cytoskeleton organization GO:0032956 84 0.020
cellular response to external stimulus GO:0071496 88 0.020
regulation of endocytosis GO:0030100 69 0.020
positive regulation of cellular protein catabolic process GO:1903364 34 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.020
positive regulation of jun kinase activity GO:0043507 30 0.020
protein localization to plasma membrane GO:0072659 57 0.019
response to decreased oxygen levels GO:0036293 59 0.019
regulation of cell cycle g2 m phase transition GO:1902749 10 0.019
stem cell differentiation GO:0048863 268 0.019
locomotory behavior GO:0007626 195 0.019
regulation of substrate adhesion dependent cell spreading GO:1900024 12 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
cell maturation GO:0048469 127 0.019
regulation of metal ion transport GO:0010959 106 0.019
regulation of body fluid levels GO:0050878 162 0.019
inositol lipid mediated signaling GO:0048017 41 0.019
platelet activation GO:0030168 40 0.019
regulation of triglyceride metabolic process GO:0090207 17 0.019
Mouse
positive regulation of proteolysis GO:0045862 85 0.019
cerebellar cortex development GO:0021695 48 0.019
mesenchyme development GO:0060485 152 0.019
small molecule biosynthetic process GO:0044283 132 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.018
mitotic cell cycle process GO:1903047 159 0.018
regulation of dendritic spine development GO:0060998 22 0.018
response to organonitrogen compound GO:0010243 246 0.018
amide transport GO:0042886 138 0.018
oxidation reduction process GO:0055114 342 0.018
cell growth GO:0016049 130 0.018
calcium ion transmembrane transport GO:0070588 85 0.018
small molecule catabolic process GO:0044282 71 0.018
Mouse
neuronal action potential GO:0019228 54 0.018
divalent inorganic cation transport GO:0072511 178 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
learning or memory GO:0007611 148 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
positive regulation of secretion GO:0051047 130 0.018
embryonic limb morphogenesis GO:0030326 126 0.018
regulation of ossification GO:0030278 112 0.018
cell fate commitment GO:0045165 210 0.018
negative regulation of map kinase activity GO:0043407 34 0.018
negative regulation of proteolysis GO:0045861 74 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
regulation of anatomical structure size GO:0090066 178 0.018
negative regulation of protein modification process GO:0031400 163 0.018
guanosine containing compound metabolic process GO:1901068 144 0.018
lipid localization GO:0010876 126 0.018
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 73 0.018
non canonical wnt signaling pathway GO:0035567 33 0.018

Lrp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.029
congenital nervous system abnormality DOID:2490 0 0.029