Mus musculus

66 known processes

Lum

lumican

(Aliases: Ldc,SLRR2D)

Lum biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of tooth mineralization GO:0070171 1 1.000
Mouse
regulation of tooth mineralization GO:0070170 2 0.998
Mouse
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan GO:0019800 8 0.991
Mouse
negative regulation of odontogenesis GO:0042483 3 0.978
Mouse
proteoglycan metabolic process GO:0006029 38 0.977
Mouse
chondroitin sulfate metabolic process GO:0030204 17 0.924
Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.874
Mouse
mucopolysaccharide metabolic process GO:1903510 25 0.836
Mouse
aminoglycan metabolic process GO:0006022 34 0.783
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.778
Mouse
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.743
Mouse
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.737
Mouse
regulation of organ morphogenesis GO:2000027 144 0.707
Mouse
sulfur compound metabolic process GO:0006790 100 0.691
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.685
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.683
Mouse
tooth mineralization GO:0034505 9 0.580
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.557
Mouse
biomineral tissue development GO:0031214 64 0.529
Mouse
extracellular matrix organization GO:0030198 147 0.526
Zebrafish
extrinsic apoptotic signaling pathway GO:0097191 126 0.510
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.507
Mouse
peptidyl serine modification GO:0018209 83 0.489
Mouse
extracellular structure organization GO:0043062 148 0.479
Zebrafish
peptidyl amino acid modification GO:0018193 336 0.473
Mouse
negative regulation of protein activation cascade GO:2000258 3 0.447
peptide cross linking GO:0018149 10 0.409
Mouse
response to transforming growth factor beta GO:0071559 88 0.389
Mouse
response to growth factor GO:0070848 198 0.385
Mouse Rat
negative regulation of complement activation GO:0045916 3 0.379
regulation of odontogenesis GO:0042481 18 0.367
Mouse
glycosaminoglycan metabolic process GO:0030203 34 0.365
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.347
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.342
negative regulation of cell proliferation GO:0008285 296 0.326
negative regulation of biomineral tissue development GO:0070168 11 0.315
Mouse
glycoprotein metabolic process GO:0009100 116 0.291
Mouse
angiogenesis GO:0001525 201 0.284
regulation of cell adhesion GO:0030155 154 0.275
heart morphogenesis GO:0003007 178 0.267
striated muscle tissue development GO:0014706 293 0.262
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.261
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.253
odontogenesis GO:0042476 78 0.232
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.210
skin development GO:0043588 220 0.196
regulation of biomineral tissue development GO:0070167 33 0.195
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.193
negative regulation of apoptotic signaling pathway GO:2001234 104 0.192
negative regulation of angiogenesis GO:0016525 25 0.185
response to molecule of bacterial origin GO:0002237 143 0.184
negative regulation of cell proliferation involved in contact inhibition GO:0060244 3 0.177
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.167
negative regulation of hydrolase activity GO:0051346 71 0.162
macrophage chemotaxis GO:0048246 14 0.146
anatomical structure homeostasis GO:0060249 145 0.142
positive regulation of programmed cell death GO:0043068 218 0.139
ossification GO:0001503 216 0.136
protein heterooligomerization GO:0051291 14 0.133
epithelial cell proliferation GO:0050673 174 0.128
cartilage development GO:0051216 140 0.128
Rat
innate immune response GO:0045087 157 0.126
negative regulation of phosphorus metabolic process GO:0010563 184 0.121
negative regulation of phospholipase activity GO:0010519 4 0.119
response to lipopolysaccharide GO:0032496 128 0.119
regulation of defense response GO:0031347 233 0.117
cell type specific apoptotic process GO:0097285 268 0.116
trabecula formation GO:0060343 24 0.114
regulation of complement activation GO:0030449 7 0.112
negative regulation of blood vessel morphogenesis GO:2000181 25 0.109
blood vessel morphogenesis GO:0048514 285 0.107
signal transduction in absence of ligand GO:0038034 55 0.105
developmental growth involved in morphogenesis GO:0060560 138 0.101
regulation of cellular ketone metabolic process GO:0010565 66 0.101
tissue remodeling GO:0048771 102 0.099
regulation of cell growth GO:0001558 91 0.095
forebrain development GO:0030900 302 0.092
protein processing GO:0016485 163 0.092
telencephalon development GO:0021537 186 0.092
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.089
activation of immune response GO:0002253 138 0.087
negative regulation of vasculature development GO:1901343 26 0.086
organic hydroxy compound metabolic process GO:1901615 203 0.085
apoptotic signaling pathway GO:0097190 306 0.085
fibril organization GO:0097435 2 0.083
regulation of map kinase activity GO:0043405 120 0.083
cell adhesion GO:0007155 329 0.078
skeletal system morphogenesis GO:0048705 203 0.077
connective tissue development GO:0061448 179 0.076
Rat
embryonic skeletal system morphogenesis GO:0048704 91 0.070
response to organonitrogen compound GO:0010243 246 0.069
positive regulation of cell death GO:0010942 224 0.068
skeletal system development GO:0001501 356 0.068
Rat
chondrocyte development GO:0002063 24 0.066
response to oxidative stress GO:0006979 123 0.065
negative regulation of cell adhesion GO:0007162 45 0.065
regulation of peptidase activity GO:0052547 96 0.064
ras protein signal transduction GO:0007265 77 0.064
sensory perception of mechanical stimulus GO:0050954 107 0.063
palate development GO:0060021 76 0.063
negative regulation of epithelial cell proliferation GO:0050680 64 0.062
metal ion homeostasis GO:0055065 189 0.062
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.061
protein maturation GO:0051604 176 0.061
positive regulation of cellular amine metabolic process GO:0033240 5 0.061
multicellular organismal homeostasis GO:0048871 164 0.060
molting cycle GO:0042303 90 0.060
bone development GO:0060348 120 0.059
extracellular fibril organization GO:0043206 2 0.059
limb morphogenesis GO:0035108 149 0.057
single organism nuclear import GO:1902593 95 0.056
response to acid chemical GO:0001101 111 0.056
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.055
Mouse
neuron death GO:0070997 154 0.055
cytoplasmic transport GO:0016482 234 0.055
protein localization to organelle GO:0033365 185 0.055
positive regulation of nervous system development GO:0051962 221 0.055
leukocyte apoptotic process GO:0071887 71 0.054
tissue homeostasis GO:0001894 115 0.053
type b pancreatic cell proliferation GO:0044342 10 0.053
trabecula morphogenesis GO:0061383 40 0.052
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.051
digestive system development GO:0055123 200 0.051
contact inhibition GO:0060242 3 0.051
compound eye development GO:0048749 1 0.051
blood circulation GO:0008015 195 0.050
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.050
regulation of kinase activity GO:0043549 249 0.049
bone morphogenesis GO:0060349 78 0.049
mineralocorticoid biosynthetic process GO:0006705 1 0.049
immune effector process GO:0002252 321 0.049
pallium development GO:0021543 120 0.048
response to radiation GO:0009314 165 0.048
response to pain GO:0048265 26 0.048
sensory perception of sound GO:0007605 97 0.048
cardiac chamber morphogenesis GO:0003206 93 0.048
regulation of angiogenesis GO:0045765 81 0.047
respiratory tube development GO:0030323 167 0.046
regulation of intracellular protein transport GO:0033157 82 0.046
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.045
response to epidermal growth factor GO:0070849 4 0.045
negative regulation of cell substrate adhesion GO:0010812 16 0.044
neurotransmitter catabolic process GO:0042135 3 0.043
cellular response to dna damage stimulus GO:0006974 207 0.043
rho protein signal transduction GO:0007266 32 0.042
positive regulation of defense response GO:0031349 124 0.042
regulation of protein localization GO:0032880 231 0.042
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.041
appendage development GO:0048736 166 0.041
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.040
cellular response to abiotic stimulus GO:0071214 56 0.040
i kappab kinase nf kappab signaling GO:0007249 85 0.040
cellular ketone metabolic process GO:0042180 84 0.040
cell matrix adhesion GO:0007160 68 0.039
negative regulation of phosphorylation GO:0042326 166 0.039
cytokine production GO:0001816 319 0.039
regulation of cell size GO:0008361 72 0.038
pathway restricted smad protein phosphorylation GO:0060389 10 0.038
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.038
physiological cardiac muscle hypertrophy GO:0003301 3 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
clathrin coat assembly GO:0048268 2 0.038
positive regulation of wnt signaling pathway GO:0030177 45 0.038
regulation of blood pressure GO:0008217 93 0.038
neuron migration GO:0001764 122 0.037
bone trabecula formation GO:0060346 9 0.037
organ growth GO:0035265 117 0.037
formation of primary germ layer GO:0001704 77 0.037
cardiac chamber development GO:0003205 108 0.036
negative regulation of icosanoid secretion GO:0032304 1 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
regulation of inflammatory response GO:0050727 147 0.036
collagen fibril organization GO:0030199 32 0.036
Zebrafish
regulation of neuron migration GO:2001222 22 0.036
renal system development GO:0072001 225 0.035
regulation of protein secretion GO:0050708 82 0.035
regulation of system process GO:0044057 200 0.034
regulation of cell migration GO:0030334 219 0.034
hormone metabolic process GO:0042445 86 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
negative regulation of reproductive process GO:2000242 31 0.033
cellular lipid metabolic process GO:0044255 323 0.033
positive regulation of growth GO:0045927 104 0.033
protein localization to nucleus GO:0034504 121 0.033
regulation of stress activated mapk cascade GO:0032872 69 0.033
negative regulation of immune system process GO:0002683 209 0.032
cellular response to organonitrogen compound GO:0071417 145 0.031
regulation of ketone biosynthetic process GO:0010566 2 0.031
response to reactive oxygen species GO:0000302 56 0.031
regulation of androgen receptor signaling pathway GO:0060765 3 0.031
regulation of canonical wnt signaling pathway GO:0060828 82 0.031
cell growth GO:0016049 130 0.031
aorta morphogenesis GO:0035909 22 0.031
positive regulation of organic acid transport GO:0032892 11 0.031
epidermis development GO:0008544 187 0.031
muscle adaptation GO:0043500 39 0.031
negative regulation of molecular function GO:0044092 258 0.031
small molecule biosynthetic process GO:0044283 132 0.031
regulation of inward rectifier potassium channel activity GO:1901979 1 0.030
response to endoplasmic reticulum stress GO:0034976 53 0.030
spinal cord development GO:0021510 81 0.030
stem cell differentiation GO:0048863 268 0.030
negative regulation of cell development GO:0010721 169 0.030
regulation of cell substrate adhesion GO:0010810 73 0.029
fat cell differentiation GO:0045444 160 0.029
regulation of establishment of protein localization GO:0070201 181 0.029
positive regulation of dna templated transcription elongation GO:0032786 2 0.029
embryonic skeletal system development GO:0048706 120 0.029
respiratory system development GO:0060541 190 0.029
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.029
regulation of intracellular transport GO:0032386 159 0.029
bone trabecula morphogenesis GO:0061430 12 0.029
intrinsic apoptotic signaling pathway GO:0097193 132 0.029
hair follicle morphogenesis GO:0031069 29 0.029
nucleocytoplasmic transport GO:0006913 139 0.028
regulation of mapk cascade GO:0043408 248 0.028
mesenchyme development GO:0060485 152 0.027
amine metabolic process GO:0009308 45 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
metencephalon development GO:0022037 89 0.027
response to extracellular stimulus GO:0009991 127 0.027
cellular response to acid chemical GO:0071229 68 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
regulation of ras protein signal transduction GO:0046578 114 0.026
circulatory system process GO:0003013 197 0.026
regulation of execution phase of apoptosis GO:1900117 9 0.026
protein activation cascade GO:0072376 19 0.026
aldosterone metabolic process GO:0032341 2 0.026
response to organic cyclic compound GO:0014070 198 0.026
Rat
macromolecule catabolic process GO:0009057 281 0.026
long chain fatty acid import GO:0044539 2 0.025
regulation of secretion GO:0051046 274 0.025
lateral line system development GO:0048925 1 0.025
cellular response to x ray GO:0071481 2 0.025
response to steroid hormone GO:0048545 56 0.025
antimicrobial peptide biosynthetic process GO:0002777 2 0.025
cell substrate adhesion GO:0031589 130 0.025
mapk cascade GO:0000165 281 0.025
response to bmp GO:0071772 14 0.025
limb development GO:0060173 166 0.025
regulation of cytokine production GO:0001817 266 0.025
regulation of protein transport GO:0051223 163 0.024
muscle tissue development GO:0060537 308 0.024
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.024
positive regulation of cell growth GO:0030307 33 0.024
protein heterotrimerization GO:0070208 8 0.024
lipid transport GO:0006869 98 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
cellular response to epidermal growth factor stimulus GO:0071364 4 0.023
positive regulation of apoptotic signaling pathway GO:2001235 95 0.023
regulation of neuron projection development GO:0010975 169 0.023
regulation of transferase activity GO:0051338 263 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
nuclear import GO:0051170 95 0.023
placenta development GO:0001890 140 0.023
glial cell apoptotic process GO:0034349 3 0.023
multicellular organismal signaling GO:0035637 91 0.023
cellular response to lipid GO:0071396 145 0.023
regulation of cell projection organization GO:0031344 206 0.023
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.022
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.022
positive regulation of receptor activity GO:2000273 17 0.022
regulation of protein import into nucleus GO:0042306 52 0.022
nuclear transport GO:0051169 139 0.022
regulation of vasculature development GO:1901342 88 0.022
defense response to other organism GO:0098542 197 0.022
regulation of translation GO:0006417 71 0.022
regulation of cell motility GO:2000145 236 0.022
interleukin 1 alpha secretion GO:0050703 3 0.021
bmp signaling pathway GO:0030509 93 0.021
regulation of protein binding GO:0043393 60 0.021
oxidation reduction process GO:0055114 342 0.021
synaptic transmission cholinergic GO:0007271 7 0.021
transmission of nerve impulse GO:0019226 76 0.021
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.021
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.021
production of molecular mediator of immune response GO:0002440 103 0.021
regulation of hormone levels GO:0010817 211 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
jnk cascade GO:0007254 72 0.021
early endosome to late endosome transport GO:0045022 2 0.021
chondrocyte differentiation GO:0002062 72 0.020
smoothened signaling pathway GO:0007224 105 0.020
positive regulation of cellular component biogenesis GO:0044089 94 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
regulation of cell cycle GO:0051726 281 0.020
inflammatory response GO:0006954 244 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
negative regulation of mapk cascade GO:0043409 65 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.020
convergent extension involved in axis elongation GO:0060028 7 0.019
negative regulation of immune effector process GO:0002698 55 0.019
positive regulation of hormone metabolic process GO:0032352 3 0.019
regulation of cytokine secretion involved in immune response GO:0002739 4 0.019
positive regulation of steroid biosynthetic process GO:0010893 4 0.019
lipid localization GO:0010876 126 0.019
appendage morphogenesis GO:0035107 149 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
regulation of secretion by cell GO:1903530 249 0.019
dna metabolic process GO:0006259 303 0.019
cellular amine metabolic process GO:0044106 44 0.019
prostate gland morphogenesis GO:0060512 32 0.019
bone remodeling GO:0046849 53 0.019
cerebral cortex development GO:0021987 86 0.019
regulation of granulocyte chemotaxis GO:0071622 17 0.019
negative regulation of wnt signaling pathway GO:0030178 73 0.018
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 11 0.018
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
neuronal action potential GO:0019228 54 0.018
antibacterial humoral response GO:0019731 8 0.018
positive regulation of cell adhesion GO:0045785 80 0.018
positive regulation of protein transport GO:0051222 93 0.018
protein autoprocessing GO:0016540 2 0.018
negative regulation of fatty acid transport GO:2000192 1 0.018
negative regulation of protein processing GO:0010955 79 0.018
regulation of neutrophil migration GO:1902622 14 0.018
cell aggregation GO:0098743 18 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
neural crest cell fate commitment GO:0014034 1 0.018
positive regulation of monocyte chemotaxis GO:0090026 2 0.018
negative regulation of embryonic development GO:0045992 22 0.018
developmental cell growth GO:0048588 84 0.018
muscle tissue morphogenesis GO:0060415 53 0.018
cellular response to nitric oxide GO:0071732 4 0.018
regulation of muscle adaptation GO:0043502 31 0.018
positive regulation of proteolysis GO:0045862 85 0.018
regulation of lipid transport GO:0032368 36 0.017
endoderm development GO:0007492 45 0.017
negative regulation of dna replication GO:0008156 4 0.017
positive regulation of secretion GO:0051047 130 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.017
regulation of acute inflammatory response GO:0002673 27 0.017
antibacterial peptide biosynthetic process GO:0002780 2 0.017
positive regulation of cell migration GO:0030335 109 0.017
sensory perception GO:0007600 245 0.017
regulation of leukocyte apoptotic process GO:2000106 56 0.017
response to inorganic substance GO:0010035 96 0.017
granulocyte migration GO:0097530 43 0.017
muscle hypertrophy GO:0014896 24 0.017
hair follicle development GO:0001942 85 0.017
leukocyte tethering or rolling GO:0050901 3 0.016
carboxylic acid transport GO:0046942 100 0.016
digestive tract development GO:0048565 190 0.016
translation GO:0006412 93 0.016
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.016
urogenital system development GO:0001655 261 0.016
cell growth involved in cardiac muscle cell development GO:0061049 3 0.016
cellular response to external stimulus GO:0071496 88 0.016
gland development GO:0048732 330 0.016
regulation of defense response to bacterium GO:1900424 3 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of muscle system process GO:0090257 80 0.016
negative regulation of lipase activity GO:0060192 7 0.016
regulation of protein targeting GO:1903533 61 0.016
kidney development GO:0001822 213 0.016
stem cell maintenance GO:0019827 130 0.016
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
cellular chemical homeostasis GO:0055082 215 0.016
gliogenesis GO:0042063 141 0.016
response to vitamin d GO:0033280 3 0.016
protein oligomerization GO:0051259 67 0.016
neuron apoptotic process GO:0051402 142 0.016
complement activation GO:0006956 16 0.015
positive regulation of cytokine production GO:0001819 174 0.015
glucose transport GO:0015758 56 0.015
positive regulation of cell substrate adhesion GO:0010811 47 0.015
positive regulation of fatty acid oxidation GO:0046321 4 0.015
regulation of erk1 and erk2 cascade GO:0070372 71 0.015
cellular glucan metabolic process GO:0006073 32 0.015
regulation of protein processing GO:0070613 96 0.015
regulation of transmission of nerve impulse GO:0051969 1 0.015
somatotropin secreting cell differentiation GO:0060126 4 0.015
cardiac muscle hypertrophy GO:0003300 23 0.015
ear morphogenesis GO:0042471 118 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
growth plate cartilage development GO:0003417 14 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
striated muscle hypertrophy GO:0014897 24 0.015
hexose metabolic process GO:0019318 98 0.015
chemotaxis GO:0006935 247 0.015
adaptive immune response GO:0002250 155 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
digestive tract morphogenesis GO:0048546 147 0.015
inner ear morphogenesis GO:0042472 101 0.015
axon guidance GO:0007411 141 0.015
regulation of lymphocyte activation GO:0051249 240 0.014
chondrocyte morphogenesis GO:0090171 1 0.014
retina development in camera type eye GO:0060041 119 0.014
regulation of tissue remodeling GO:0034103 38 0.014
regulation of protein activation cascade GO:2000257 7 0.014
negative regulation of protein maturation GO:1903318 79 0.014
muscle cell proliferation GO:0033002 52 0.014
myeloid cell differentiation GO:0030099 233 0.014
sequestering of metal ion GO:0051238 19 0.014
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.014
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.014
tendon cell differentiation GO:0035990 4 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
anatomical structure maturation GO:0071695 49 0.014
response to catecholamine GO:0071869 4 0.014
regulation of jnk cascade GO:0046328 62 0.014
stress activated protein kinase signaling cascade GO:0031098 81 0.014
cellularization GO:0007349 1 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
antimicrobial peptide production GO:0002775 2 0.014
cellular response to bmp stimulus GO:0071773 14 0.014
developmental maturation GO:0021700 193 0.013
convergent extension GO:0060026 14 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
tendon development GO:0035989 6 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
fatty acid metabolic process GO:0006631 121 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of antibacterial peptide production GO:0002786 1 0.013
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 5 0.013
response to peptide GO:1901652 136 0.013
regulation of protein kinase activity GO:0045859 232 0.013
carbohydrate homeostasis GO:0033500 128 0.013
homeostasis of number of cells GO:0048872 210 0.013
anion transport GO:0006820 177 0.013
salivary gland morphogenesis GO:0007435 33 0.013
regulation of reproductive process GO:2000241 66 0.013
axonogenesis GO:0007409 274 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
face morphogenesis GO:0060325 29 0.013
gastrulation GO:0007369 116 0.013
positive regulation of antimicrobial peptide production GO:0002225 1 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regulation of cytokine production involved in immune response GO:0002718 26 0.012
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.012
camera type eye development GO:0043010 266 0.012
Zebrafish
hair cycle GO:0042633 90 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
blood vessel remodeling GO:0001974 33 0.012
endochondral bone morphogenesis GO:0060350 50 0.012
regulation of aldosterone metabolic process GO:0032344 1 0.012
regulation of steroid hormone biosynthetic process GO:0090030 4 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
actin cytoskeleton organization GO:0030036 220 0.012
negative regulation of endopeptidase activity GO:0010951 44 0.012
intracellular protein transport GO:0006886 204 0.012
negative regulation of nervous system development GO:0051961 156 0.012
positive regulation of catenin import into nucleus GO:0035413 2 0.012
activation of mapk activity GO:0000187 59 0.012
regulation of cell cycle process GO:0010564 160 0.012
branching involved in prostate gland morphogenesis GO:0060442 15 0.012
negative regulation of camp mediated signaling GO:0043951 3 0.012
cardiac ventricle morphogenesis GO:0003208 50 0.012
cellular response to inorganic substance GO:0071241 37 0.012
protein targeting GO:0006605 143 0.012
defense response to bacterium GO:0042742 119 0.012
response to monoamine GO:0071867 4 0.012
peptide biosynthetic process GO:0043043 11 0.012
establishment of tissue polarity GO:0007164 28 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
Zebrafish
negative regulation of peptidase activity GO:0010466 46 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of neuron differentiation GO:0045664 281 0.011
regulation of receptor activity GO:0010469 41 0.011
endocrine process GO:0050886 39 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
regulation of response to wounding GO:1903034 189 0.011

Lum disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.339
muscular disease DOID:0080000 0 0.339
disease of anatomical entity DOID:7 0 0.339
musculoskeletal system disease DOID:17 0 0.339
muscle tissue disease DOID:66 0 0.339
hemolytic anemia DOID:583 0 0.222
hemolytic uremic syndrome DOID:12554 0 0.222
immune system disease DOID:2914 0 0.222
normocytic anemia DOID:720 0 0.222
anemia DOID:2355 0 0.222
hematopoietic system disease DOID:74 0 0.222
collagen disease DOID:854 0 0.078
connective tissue disease DOID:65 0 0.078
osteoporosis DOID:11476 0 0.059
bone remodeling disease DOID:0080005 0 0.059
bone disease DOID:0080001 0 0.059
bone resorption disease DOID:0080011 0 0.059
ehlers danlos syndrome DOID:13359 0 0.029
heart disease DOID:114 0 0.023
cardiovascular system disease DOID:1287 0 0.023
disease by infectious agent DOID:0050117 0 0.022
viral infectious disease DOID:934 0 0.022
nervous system disease DOID:863 0 0.020
cardiomyopathy DOID:0050700 0 0.020
intrinsic cardiomyopathy DOID:0060036 0 0.020
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015