IMP

Process View

Mus musculus

14 genes annotated in mouse

response to bmp

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to bmp"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to bmp" (in gray)

Name	Description	Probability	Func Analog Organism
Gata4	GATA binding protein 4	0.991	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.978	Mouse
Msx1	homeobox, msh-like 1	0.954
Hand2	heart and neural crest derivatives expressed transcript 2	0.941	Mouse
Neurod1	neurogenic differentiation 1	0.904	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	0.888	Mouse
Shh	sonic hedgehog	0.870
Prrx2	paired related homeobox 2	0.867	Mouse
Col1a1	collagen, type I, alpha 1	0.860	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.843
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.785
Col3a1	collagen, type III, alpha 1	0.690	Mouse
Col5a1	collagen, type V, alpha 1	0.673	Mouse
Gata1	GATA binding protein 1	0.640	Mouse
Dlx5	distal-less homeobox 5	0.564
Otx2	orthodenticle homolog 2 (Drosophila)	0.551
Sox9	SRY-box containing gene 9	0.546
Isl1	ISL1 transcription factor, LIM/homeodomain	0.519
Nhlh1	nescient helix loop helix 1	0.404	Mouse
Col1a2	collagen, type I, alpha 2	0.401	Mouse
Gli3	GLI-Kruppel family member GLI3	0.389
Tgfb2	transforming growth factor, beta 2	0.379
Smad1	MAD homolog 1 (Drosophila)	0.360
Tal1	T-cell acute lymphocytic leukemia 1	0.351	Mouse
Prrx1	paired related homeobox 1	0.334	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.310
Ptf1a	pancreas specific transcription factor, 1a	0.254	Mouse
Gli2	GLI-Kruppel family member GLI2	0.253
Eya1	eyes absent 1 homolog (Drosophila)	0.247
Hoxa1	homeobox A1	0.242
Smad2	MAD homolog 2 (Drosophila)	0.236	Mouse
Foxc2	forkhead box C2	0.235
Fgf8	fibroblast growth factor 8	0.230
Sfrp2	secreted frizzled-related protein 2	0.221
Col5a2	collagen, type V, alpha 2	0.217	Mouse
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.204
Ebf3	early B-cell factor 3	0.200
Smad3	MAD homolog 3 (Drosophila)	0.195	Mouse
Apc	adenomatosis polyposis coli	0.190
Bmp4	bone morphogenetic protein 4	0.176	Rat
Zfpm2	zinc finger protein, multitype 2	0.174
Mrc2	mannose receptor, C type 2	0.169
Acvr1	activin A receptor, type 1	0.154
Pax3	paired box gene 3	0.146
Smad6	MAD homolog 6 (Drosophila)	0.144	Mouse
Col6a2	collagen, type VI, alpha 2	0.144
Axin1	axin 1	0.143
Obsl1	obscurin-like 1	0.142
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.123
Bmp7	bone morphogenetic protein 7	0.117
Col6a3	collagen, type VI, alpha 3	0.116
Snai1	snail homolog 1 (Drosophila)	0.112
Cdh23	cadherin 23 (otocadherin)	0.102
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.099
Kiss1	KiSS-1 metastasis-suppressor	0.095
Efna2	ephrin A2	0.091
Hes5	hairy and enhancer of split 5 (Drosophila)	0.087
Acan	aggrecan	0.086
Srrm4	serine/arginine repetitive matrix 4	0.085
Mecom	MDS1 and EVI1 complex locus	0.082
Erbb2ip	Erbb2 interacting protein	0.080
Epor	erythropoietin receptor	0.079
Gata6	GATA binding protein 6	0.079
Fgfr2	fibroblast growth factor receptor 2	0.077
Bgn	biglycan	0.077
Eng	endoglin	0.075
Chrd	chordin	0.075
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.074
Onecut1	one cut domain, family member 1	0.072
Gsc	goosecoid homeobox	0.068
Thbs1	thrombospondin 1	0.065
Jag1	jagged 1	0.062
Smad7	MAD homolog 7 (Drosophila)	0.062	Mouse
Pou4f3	POU domain, class 4, transcription factor 3	0.059
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.058
Foxc1	forkhead box C1	0.056
Col6a1	collagen, type VI, alpha 1	0.055
Pax9	paired box gene 9	0.054
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.053
Foxg1	forkhead box G1	0.053
Foxf1a	forkhead box F1a	0.053
Fstl1	follistatin-like 1	0.052
Col4a2	collagen, type IV, alpha 2	0.051
Rnf111	ring finger 111	0.050
S1pr2	sphingosine-1-phosphate receptor 2	0.048
Col22a1	collagen, type XXII, alpha 1	0.047
Loxl1	lysyl oxidase-like 1	0.045
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.045
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.045
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.043
Col16a1	collagen, type XVI, alpha 1	0.043
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.043
Pthlh	parathyroid hormone-like peptide	0.042
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.042
Srpx	sushi-repeat-containing protein	0.042
Runx2	runt related transcription factor 2	0.042
Dlx2	distal-less homeobox 2	0.042	Mouse
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.041
Notch1	Notch gene homolog 1 (Drosophila)	0.041
Lox	lysyl oxidase	0.041
Eln	elastin	0.041
Twist2	twist homolog 2 (Drosophila)	0.039	Mouse
Hhex	hematopoietically expressed homeobox	0.039
Hoxd13	homeobox D13	0.039
Gfi1b	growth factor independent 1B	0.039
Pbx1	pre B-cell leukemia transcription factor 1	0.038
Csf1	colony stimulating factor 1 (macrophage)	0.038
En1	engrailed 1	0.038
Tcfap2a	transcription factor AP-2, alpha	0.037
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.037
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.037
Bmp1	bone morphogenetic protein 1	0.036
Ctsk	cathepsin K	0.035
Gbx2	gastrulation brain homeobox 2	0.035
Tgfbr2	transforming growth factor, beta receptor II	0.035
Amh	anti-Mullerian hormone	0.035
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.034
Hoxc5	homeobox C5	0.034
Hoxb1	homeobox B1	0.034
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.032
Darc	Duffy blood group, chemokine receptor	0.032
Mn1	meningioma 1	0.032
Col11a1	collagen, type XI, alpha 1	0.031	Mouse
Neurog2	neurogenin 2	0.031	Mouse
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.031
Hic1	hypermethylated in cancer 1	0.031
Pcolce	procollagen C-endopeptidase enhancer protein	0.031
Alx1	ALX homeobox 1	0.031
Nrg1	neuregulin 1	0.030
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.029
Efnb1	ephrin B1	0.029
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.029
Fzd2	frizzled homolog 2 (Drosophila)	0.029
Msx2	homeobox, msh-like 2	0.029
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.029
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.029	Mouse
Mab21l2	mab-21-like 2 (C. elegans)	0.029
Cd248	CD248 antigen, endosialin	0.027
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.027
Sox10	SRY-box containing gene 10	0.027
Gata2	GATA binding protein 2	0.027	Mouse
Sparc	secreted acidic cysteine rich glycoprotein	0.027
Prkg1	protein kinase, cGMP-dependent, type I	0.026
Insm1	insulinoma-associated 1	0.026
Capn6	calpain 6	0.026
Ermap	erythroblast membrane-associated protein	0.026
Fgfr1	fibroblast growth factor receptor 1	0.026
Lef1	lymphoid enhancer binding factor 1	0.026
Ush1g	Usher syndrome 1G homolog (human)	0.026
Klf3	Kruppel-like factor 3 (basic)	0.025
Foxd3	forkhead box D3	0.025
Leprel2	leprecan-like 2	0.025
Tmprss3	transmembrane protease, serine 3	0.025
Lum	lumican	0.025
Tlx3	T-cell leukemia, homeobox 3	0.025
Cbfb	core binding factor beta	0.024
Neurog3	neurogenin 3	0.024	Mouse
Col2a1	collagen, type II, alpha 1	0.024
Mfap4	microfibrillar-associated protein 4	0.024
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.024
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.023
Mfap2	microfibrillar-associated protein 2	0.023
Ctnnb1	catenin (cadherin associated protein), beta 1	0.022
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.022
Wnt6	wingless-related MMTV integration site 6	0.022
Lhx3	LIM homeobox protein 3	0.022
Col13a1	collagen, type XIII, alpha 1	0.022
Loxl3	lysyl oxidase-like 3	0.022
Pou4f2	POU domain, class 4, transcription factor 2	0.021
Gsx2	GS homeobox 2	0.021
Bnc1	basonuclin 1	0.020
Myog	myogenin	0.020
Pax6	paired box gene 6	0.020
Gpr124	G protein-coupled receptor 124	0.020
Axin2	axin2	0.020
Efs	embryonal Fyn-associated substrate	0.020
Tbx1	T-box 1	0.020
Gdnf	glial cell line derived neurotrophic factor	0.020
Hoxb4	homeobox B4	0.020
Neurog1	neurogenin 1	0.020	Mouse
Dlk1	delta-like 1 homolog (Drosophila)	0.020
Notch3	Notch gene homolog 3 (Drosophila)	0.019
Pitx1	paired-like homeodomain transcription factor 1	0.019
Ccdc80	coiled-coil domain containing 80	0.019
Epha3	Eph receptor A3	0.019
Tpm2	tropomyosin 2, beta	0.019
Kcnd1	potassium voltage-gated channel, Shal-related family, member 1	0.019
Gja4	gap junction protein, alpha 4	0.018
Robo3	roundabout homolog 3 (Drosophila)	0.018
Rbp1	retinol binding protein 1, cellular	0.018
Dlx1	distal-less homeobox 1	0.018
Sim2	single-minded homolog 2 (Drosophila)	0.018
Ptch1	patched homolog 1	0.018
Dcx	doublecortin	0.018
Col9a1	collagen, type IX, alpha 1	0.018
Twist1	twist homolog 1 (Drosophila)	0.018	Mouse
Pitx3	paired-like homeodomain transcription factor 3	0.017
Fbln2	fibulin 2	0.017
Dlx6	distal-less homeobox 6	0.017
Lhx5	LIM homeobox protein 5	0.017
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.017
Dll4	delta-like 4 (Drosophila)	0.017
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.017
Pdx1	pancreatic and duodenal homeobox 1	0.017
Tcf21	transcription factor 21	0.017
Lmx1a	LIM homeobox transcription factor 1 alpha	0.016
Adcy4	adenylate cyclase 4	0.016
Wisp1	WNT1 inducible signaling pathway protein 1	0.016
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.016
Sh3pxd2a	SH3 and PX domains 2A	0.016
Lep	leptin	0.016
Atoh8	atonal homolog 8 (Drosophila)	0.016
Ltbp2	latent transforming growth factor beta binding protein 2	0.016
Tnmd	tenomodulin	0.015	Rat
Arsi	arylsulfatase i	0.015
Ntf3	neurotrophin 3	0.015
Ebf2	early B-cell factor 2	0.015
Hes1	hairy and enhancer of split 1 (Drosophila)	0.015
Col11a2	collagen, type XI, alpha 2	0.015	Mouse
Inhba	inhibin beta-A	0.015
Yap1	yes-associated protein 1	0.015
Mmp23	matrix metallopeptidase 23	0.015
Matn1	matrilin 1, cartilage matrix protein	0.015
Gja1	gap junction protein, alpha 1	0.015
Mypop	Myb-related transcription factor, partner of profilin	0.015
Col8a1	collagen, type VIII, alpha 1	0.015
Grb10	growth factor receptor bound protein 10	0.015
Trp63	transformation related protein 63	0.015
Ptk2	PTK2 protein tyrosine kinase 2	0.015
Trim10	tripartite motif-containing 10	0.015
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.015
Mfap5	microfibrillar associated protein 5	0.015
Col14a1	collagen, type XIV, alpha 1	0.014
Zfp503	zinc finger protein 503	0.014
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.014
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.014
Alx3	aristaless-like homeobox 3	0.014
Hoxd3	homeobox D3	0.014
Insm2	insulinoma-associated 2	0.014
Ednra	endothelin receptor type A	0.014
Krt14	keratin 14	0.014
Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	0.014
Gpc3	glypican 3	0.013
Cel	carboxyl ester lipase	0.013
Grem1	gremlin 1	0.013
Satb2	special AT-rich sequence binding protein 2	0.013
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.013
Acta2	actin, alpha 2, smooth muscle, aorta	0.013
Sox2	SRY-box containing gene 2	0.013
Nrtn	neurturin	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Dcc	deleted in colorectal carcinoma	0.013
Cpxm1	carboxypeptidase X 1 (M14 family)	0.013
Klf1	Kruppel-like factor 1 (erythroid)	0.013
Sox7	SRY-box containing gene 7	0.012
Mdk	midkine	0.012
Tcf3	transcription factor 3	0.012
Matn4	matrilin 4	0.012
Lhx9	LIM homeobox protein 9	0.012
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.012
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.012
Hmx3	H6 homeobox 3	0.012
Col12a1	collagen, type XII, alpha 1	0.012
Bach1	BTB and CNC homology 1	0.012
Prox1	prospero-related homeobox 1	0.012
Sox4	SRY-box containing gene 4	0.012
Col15a1	collagen, type XV, alpha 1	0.012
Myod1	myogenic differentiation 1	0.012
Cpz	carboxypeptidase Z	0.012
Nrk	Nik related kinase	0.012
Hr	hairless	0.012
Irx4	Iroquois related homeobox 4 (Drosophila)	0.012
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.012
Hoxd1	homeobox D1	0.012
Shox2	short stature homeobox 2	0.011
BC057022	cDNA sequence BC057022	0.011
Wnt11	wingless-related MMTV integration site 11	0.011
Emilin1	elastin microfibril interfacer 1	0.011
Bcl6b	B-cell CLL/lymphoma 6, member B	0.011
Epx	eosinophil peroxidase	0.011
Crb2	crumbs homolog 2 (Drosophila)	0.011
Sfrp5	secreted frizzled-related sequence protein 5	0.011
Ptgir	prostaglandin I receptor (IP)	0.011
Fbn1	fibrillin 1	0.011
9030425E11Rik	RIKEN cDNA 9030425E11 gene	0.011
Gata5	GATA binding protein 5	0.011
Vax1	ventral anterior homeobox containing gene 1	0.011
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.011
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.011
Adra2a	adrenergic receptor, alpha 2a	0.011
Zbtb46	zinc finger and BTB domain containing 46	0.011
Dll1	delta-like 1 (Drosophila)	0.011
Lhx6	LIM homeobox protein 6	0.011
Foxd2	forkhead box D2	0.011
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.011
Myf5	myogenic factor 5	0.011
Tmem8c	transmembrane protein 8C	0.011
Zfp703	zinc finger protein 703	0.011
Cdca3	cell division cycle associated 3	0.011
Prph	peripherin	0.011
Cdh5	cadherin 5	0.010
Rtn4rl2	reticulon 4 receptor-like 2	0.010
Fgf4	fibroblast growth factor 4	0.010
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.010
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.010
Mybpc3	myosin binding protein C, cardiac	0.010
Tac2	tachykinin 2	0.010