|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
1.000
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
1.000
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
1.000
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
1.000
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
1.000
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
1.000
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
1.000
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
1.000
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
1.000
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.999
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.999
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.999
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.999
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.999
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.999
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.999
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.999
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.999
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.999
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.999
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.999
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.999
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.999
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.999
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.999
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.999
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.999
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.998
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.998
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.998
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.998
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.998
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.998
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.998
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.998
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.997
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.997
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.996
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.996
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.996
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.996
|
|
|
|
regulation of type ii hypersensitivity
|
GO:0002892 |
4 |
0.996
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.995
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.995
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.995
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.995
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.994
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.994
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.994
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.993
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.992
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.992
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.992
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.992
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.992
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.992
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.991
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.991
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.990
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.990
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.990
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.990
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.989
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.989
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.989
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.989
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.988
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.988
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.987
|
|
|
|
regulation of type iia hypersensitivity
|
GO:0001796 |
4 |
0.987
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.986
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.986
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.986
|
|
|
|
regulation of intestinal cholesterol absorption
|
GO:0030300 |
4 |
0.986
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.986
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.985
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.985
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.984
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.984
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.982
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.982
|
|
|
|
positive regulation of sterol transport
|
GO:0032373 |
9 |
0.982
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.981
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.981
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.981
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.980
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.977
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.977
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.976
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.976
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.974
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.974
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.974
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.973
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.973
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.972
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.972
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.972
|
|
|
|
positive regulation of type ii hypersensitivity
|
GO:0002894 |
4 |
0.971
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.971
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.970
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.966
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.966
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.966
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.966
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.965
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.962
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.962
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.961
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.961
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.961
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.960
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.960
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.960
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.960
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.959
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.959
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.959
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.957
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.956
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.956
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.953
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.953
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.952
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.950
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.948
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.948
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.947
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.946
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.946
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.945
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.943
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.942
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.942
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.941
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.940
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.939
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.939
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.938
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.938
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.937
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.937
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.934
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.933
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.932
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.932
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
9 |
0.931
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.930
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.929
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.926
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.926
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.926
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.926
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.924
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.924
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.922
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.920
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.919
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.918
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.915
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.913
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.913
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.913
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.911
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.911
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.910
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.909
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.909
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.907
|
|
|
|
high density lipoprotein particle assembly
|
GO:0034380 |
3 |
0.906
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.905
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.904
|
|
|
|
response to host defenses
|
GO:0052200 |
3 |
0.902
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.902
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.902
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.900
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.899
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.898
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.896
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.890
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.889
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.889
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.887
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.884
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.881
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.877
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.875
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.873
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.873
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.873
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.872
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.870
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.869
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.867
|
|
|
|
induction by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052558 |
1 |
0.865
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.863
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.862
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.862
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.860
|
|
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.857
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.855
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.852
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.849
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.848
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.847
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.847
|
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.843
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.842
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.839
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.838
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.836
|
|
|
|
positive regulation of cholesterol esterification
|
GO:0010873 |
1 |
0.834
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.832
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.831
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.830
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.830
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.828
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.828
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.828
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.827
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.825
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.824
|
|
|
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
GO:0061081 |
9 |
0.824
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.821
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.821
|
|
|
|
regulation of acute inflammatory response to antigenic stimulus
|
GO:0002864 |
10 |
0.821
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.819
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.819
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.817
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.813
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.813
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
11 |
0.813
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.809
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.808
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.808
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.807
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.804
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.801
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.800
|
|
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.798
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.798
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.796
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.795
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.794
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.794
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.791
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.791
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.791
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.789
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.789
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.788
|
|
|
|
organophosphate ester transport
|
GO:0015748 |
28 |
0.788
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.785
|
|
|
|
nitric oxide mediated signal transduction
|
GO:0007263 |
4 |
0.779
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.777
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.776
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.775
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
3 |
0.773
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.770
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.770
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.768
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.767
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
0 |
0.766
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.765
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.764
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.763
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
7 |
0.758
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.758
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.757
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.755
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.755
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.754
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.753
|
|
|
|
reverse cholesterol transport
|
GO:0043691 |
6 |
0.752
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
14 |
0.752
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.751
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.750
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.750
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.749
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.746
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.743
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.743
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.741
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.732
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.732
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.730
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.729
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.729
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.725
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.721
|
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.721
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.721
|
|
|
|
regulation of cholesterol biosynthetic process
|
GO:0045540 |
8 |
0.719
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.719
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.717
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.709
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.709
|
|
|
|
regulation of metanephric mesenchymal cell migration
|
GO:2000589 |
2 |
0.707
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.707
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.706
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.703
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.702
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.702
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.701
|
|
|
|
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070430 |
1 |
0.699
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.698
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.698
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.696
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.691
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.689
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.688
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.686
|
|
|
|
cholesterol esterification
|
GO:0034435 |
3 |
0.682
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.682
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
20 |
0.680
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.680
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.679
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.672
|
|
|
|
phospholipid homeostasis
|
GO:0055091 |
6 |
0.670
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.668
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.666
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.666
|
|
|
|
regulation of phospholipid efflux
|
GO:1902994 |
2 |
0.666
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.665
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.664
|
|
|
|
regulation of type i hypersensitivity
|
GO:0001810 |
4 |
0.664
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.664
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.663
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.660
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.655
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.655
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.653
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
5 |
0.652
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.652
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.651
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.650
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.649
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.648
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.647
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.646
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.643
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.641
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.639
|
|
|
|
positive regulation of type iia hypersensitivity
|
GO:0001798 |
4 |
0.639
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.638
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.633
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.632
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.630
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.628
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.628
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.627
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.627
|
|
|
|
positive regulation of complement activation
|
GO:0045917 |
2 |
0.627
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.626
|
|
|
|
response to defense related nitric oxide production by other organism involved in symbiotic interaction
|
GO:0052551 |
2 |
0.624
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.622
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.622
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.621
|
|
|
|
metanephric mesenchymal cell migration
|
GO:0035789 |
2 |
0.620
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.617
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.617
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.615
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.615
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.613
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.613
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.613
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.611
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.606
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.604
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.603
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.603
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.602
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.599
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.599
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.599
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.595
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.595
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.591
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.590
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.589
|
|
|
|
activation of membrane attack complex
|
GO:0001905 |
4 |
0.589
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.587
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.582
|
|
|
|
negative regulation of mast cell apoptotic process
|
GO:0033026 |
4 |
0.582
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.582
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.580
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.578
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.577
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.574
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.573
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.570
|
|
|
|
regulation of prostaglandin endoperoxide synthase activity
|
GO:0060584 |
2 |
0.570
|
|
|
|
regulation of type iii hypersensitivity
|
GO:0001803 |
3 |
0.570
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.570
|
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.566
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.565
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.563
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.563
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.562
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.561
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.560
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.560
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.559
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.559
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.558
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.557
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.556
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.555
|
|
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.550
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.545
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.540
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.539
|
|
|
|
phospholipid efflux
|
GO:0033700 |
3 |
0.537
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.534
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.534
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.531
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.528
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.527
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.522
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.522
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.522
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.522
|
|
|
|
response to dexamethasone
|
GO:0071548 |
8 |
0.520
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.520
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
5 |
0.518
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.512
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.510
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.510
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.508
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.503
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
5 |
0.503
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.502
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.500
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.499
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.498
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.496
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.495
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.492
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.492
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.489
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.486
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.486
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.480
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.478
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class i
|
GO:0042590 |
6 |
0.473
|
|
|
|
mhc class ii biosynthetic process
|
GO:0045342 |
8 |
0.473
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.473
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.470
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.469
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.469
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.468
|
|
|
|
positive regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002925 |
6 |
0.468
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.465
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.464
|
|
|
|
positive regulation of mhc class ii biosynthetic process
|
GO:0045348 |
4 |
0.462
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
28 |
0.461
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.459
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.452
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.452
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.452
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.449
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.446
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.446
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.446
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.441
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.439
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.438
|
|
|
|
negative regulation of type i hypersensitivity
|
GO:0001811 |
1 |
0.437
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.437
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.436
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.433
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
23 |
0.429
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.426
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.425
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.420
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.419
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.417
|
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
12 |
0.412
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.410
|
|
|
|
positive regulation of interleukin 6 biosynthetic process
|
GO:0045410 |
6 |
0.410
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.410
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.410
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.409
|
|
|
|
cgmp mediated signaling
|
GO:0019934 |
3 |
0.408
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.406
|
|
