IMP

Process View

Mus musculus

8 genes annotated in mouse

response to dexamethasone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to dexamethasone"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to dexamethasone" (in gray)

Name	Description	Probability	Func Analog Organism
Ptgs2	prostaglandin-endoperoxide synthase 2	0.952
Lepr	leptin receptor	0.902
Nos1	nitric oxide synthase 1, neuronal	0.864
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.743	Mouse
Tgfb1	transforming growth factor, beta 1	0.705	Mouse Rat
Lep	leptin	0.579
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.554	Rat
Lyz2	lysozyme 2	0.520
Fas	Fas (TNF receptor superfamily member 6)	0.517
Ren1	renin 1 structural	0.511
Vdr	vitamin D receptor	0.491
Nos3	nitric oxide synthase 3, endothelial cell	0.438
Pparg	peroxisome proliferator activated receptor gamma	0.338
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.295
Casp1	caspase 1	0.286	Mouse
Hif1a	hypoxia inducible factor 1, alpha subunit	0.206
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.195	Zebrafish Rat
Stat3	signal transducer and activator of transcription 3	0.192
Kit	kit oncogene	0.170
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.154
Mstn	myostatin	0.150
Tlr4	toll-like receptor 4	0.135
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.121
Fbn1	fibrillin 1	0.113
Vegfa	vascular endothelial growth factor A	0.109
Cav1	caveolin 1, caveolae protein	0.097
Agtr2	angiotensin II receptor, type 2	0.095
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.091
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.091
Slc12a1	solute carrier family 12, member 1	0.090
Dmd	dystrophin, muscular dystrophy	0.077
Rb1	retinoblastoma 1	0.075
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.073
Fshr	follicle stimulating hormone receptor	0.070
Il18	interleukin 18	0.069
Gbp5	guanylate binding protein 5	0.062
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.061
Pde8b	phosphodiesterase 8B	0.060
Il6st	interleukin 6 signal transducer	0.058
Lox	lysyl oxidase	0.058
Plau	plasminogen activator, urokinase	0.055
Pycard	PYD and CARD domain containing	0.053
Vav2	vav 2 oncogene	0.051
Jak2	Janus kinase 2	0.050
Aim2	absent in melanoma 2	0.047
Il6	interleukin 6	0.044
Csf1	colony stimulating factor 1 (macrophage)	0.043
Foxc1	forkhead box C1	0.042
Cd44	CD44 antigen	0.041
Il1r1	interleukin 1 receptor, type I	0.040
Inhba	inhibin beta-A	0.035
Bdkrb2	bradykinin receptor, beta 2	0.034
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.033
Stat5b	signal transducer and activator of transcription 5B	0.033
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.032
Col1a1	collagen, type I, alpha 1	0.032
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.028
Fst	follistatin	0.028
Ldlr	low density lipoprotein receptor	0.027
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.027
Vav3	vav 3 oncogene	0.026
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.026	Rat
ND6	NADH dehydrogenase subunit 6	0.025
Pten	phosphatase and tensin homolog	0.025
Adam17	a disintegrin and metallopeptidase domain 17	0.022
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.022
Spp1	secreted phosphoprotein 1	0.022
Ifngr1	interferon gamma receptor 1	0.021
Insr	insulin receptor	0.021
Stat5a	signal transducer and activator of transcription 5A	0.021
Il10	interleukin 10	0.020
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.020	Rat
Esr1	estrogen receptor 1 (alpha)	0.020
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.020
Il1b	interleukin 1 beta	0.019
Nos2	nitric oxide synthase 2, inducible	0.019	Rat
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.019
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.018	Rat
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.018
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.018
Wwox	WW domain-containing oxidoreductase	0.018
Ptprc	protein tyrosine phosphatase, receptor type, C	0.016
Socs5	suppressor of cytokine signaling 5	0.016
Kl	klotho	0.016
Apoe	apolipoprotein E	0.016
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.016
Eif3f	eukaryotic translation initiation factor 3, subunit F	0.016
B2m	beta-2 microglobulin	0.016
Agtr1a	angiotensin II receptor, type 1a	0.016	Rat
Egfr	epidermal growth factor receptor	0.016	Rat
Msx2	homeobox, msh-like 2	0.016
Prlr	prolactin receptor	0.016
Sptlc2	serine palmitoyltransferase, long chain base subunit 2	0.015
Myog	myogenin	0.015
Emx1	empty spiracles homolog 1 (Drosophila)	0.015
Cyr61	cysteine rich protein 61	0.014
Rp1	retinitis pigmentosa 1 (human)	0.014
Rora	RAR-related orphan receptor alpha	0.014
Ccl2	chemokine (C-C motif) ligand 2	0.014
Irs1	insulin receptor substrate 1	0.014
Ccr1	chemokine (C-C motif) receptor 1	0.014
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.014
Wt1	Wilms tumor 1 homolog	0.013
Socs1	suppressor of cytokine signaling 1	0.013
Akr1c21	aldo-keto reductase family 1, member C21	0.013
Osmr	oncostatin M receptor	0.013
Gab1	growth factor receptor bound protein 2-associated protein 1	0.012
Mmp9	matrix metallopeptidase 9	0.012
Vhl	von Hippel-Lindau tumor suppressor	0.012
Foxo3	forkhead box O3	0.012
Tgfbr1	transforming growth factor, beta receptor I	0.012
Smad3	MAD homolog 3 (Drosophila)	0.012
Plin1	perilipin 1	0.012
Ahr	aryl-hydrocarbon receptor	0.012
Tgfbr2	transforming growth factor, beta receptor II	0.011
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.011	Rat
Pomc	pro-opiomelanocortin-alpha	0.011
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.011
Fadd	Fas (TNFRSF6)-associated via death domain	0.010
Agtrap	angiotensin II, type I receptor-associated protein	0.010
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.010
Inhbc	inhibin beta-C	0.010