Mus musculus

144 known processes

Mapk1

mitogen-activated protein kinase 1

(Aliases: Erk2,AA407128,PRKM2,AU018647,MAPK2,C78273,p42mapk,p41mapk,Prkm1,9030612K14Rik,ERK)

Mapk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to arsenic containing substance GO:0071243 4 0.981
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.914
Yeast
negative regulation of intracellular signal transduction GO:1902532 167 0.892
Yeast
negative regulation of phosphorus metabolic process GO:0010563 184 0.887
Yeast
negative regulation of phosphorylation GO:0042326 166 0.868
Yeast
cellular response to cadmium ion GO:0071276 3 0.857
Fly
regulation of erk1 and erk2 cascade GO:0070372 71 0.825
Fly
negative regulation of mapk cascade GO:0043409 65 0.825
Yeast
regulation of mapk cascade GO:0043408 248 0.775
Yeast Fly
stress activated protein kinase signaling cascade GO:0031098 81 0.724
Fly
small gtpase mediated signal transduction GO:0007264 97 0.675
Worm Fly
mapk cascade GO:0000165 281 0.644
jun phosphorylation GO:0007258 41 0.633
Fly
jnk cascade GO:0007254 72 0.616
Fly
cellular amino acid metabolic process GO:0006520 103 0.612
regulation of cellular amino acid metabolic process GO:0006521 5 0.562
response to lipopolysaccharide GO:0032496 128 0.552
cellular lipid metabolic process GO:0044255 323 0.533
response to growth factor GO:0070848 198 0.528
Human
response to oxidative stress GO:0006979 123 0.496
Fly
negative regulation of protein phosphorylation GO:0001933 126 0.483
cellular ketone metabolic process GO:0042180 84 0.472
positive regulation of cellular amine metabolic process GO:0033240 5 0.465
mitotic cell cycle process GO:1903047 159 0.454
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.431
regulation of defense response GO:0031347 233 0.430
cellular response to dna damage stimulus GO:0006974 207 0.427
embryonic placenta development GO:0001892 98 0.421
cellular amine metabolic process GO:0044106 44 0.407
histone modification GO:0016570 159 0.404
positive regulation of intracellular transport GO:0032388 70 0.403
Yeast
amine metabolic process GO:0009308 45 0.399
negative regulation of jun kinase activity GO:0043508 9 0.397
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.396
Human Fly
positive regulation of protein transport GO:0051222 93 0.395
Yeast
establishment of protein localization to organelle GO:0072594 118 0.377
Rat
positive regulation of cytoplasmic transport GO:1903651 40 0.375
Yeast
blood vessel morphogenesis GO:0048514 285 0.374
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.372
Yeast
regulation of brown fat cell differentiation GO:0090335 5 0.371
peptidyl amino acid modification GO:0018193 336 0.356
regulation of cell cycle GO:0051726 281 0.349
Yeast Worm
nucleocytoplasmic transport GO:0006913 139 0.345
Yeast Rat
brown fat cell differentiation GO:0050873 36 0.333
positive regulation of mapk cascade GO:0043410 170 0.333
Fly
chromatin modification GO:0016568 187 0.332
regulation of intracellular transport GO:0032386 159 0.327
Yeast
regulation of establishment of protein localization GO:0070201 181 0.322
Yeast
regulation of cellular ketone metabolic process GO:0010565 66 0.321
apoptotic signaling pathway GO:0097190 306 0.317
positive regulation of organelle organization GO:0010638 128 0.314
regionalization GO:0003002 337 0.312
Fly
negative regulation of map kinase activity GO:0043407 34 0.312
immune response activating signal transduction GO:0002757 116 0.307
regulation of cellular response to stress GO:0080135 159 0.303
Fly
regulation of innate immune response GO:0045088 91 0.302
regulation of protein serine threonine kinase activity GO:0071900 157 0.298
regulation of apoptotic signaling pathway GO:2001233 197 0.296
cellular response to cytokine stimulus GO:0071345 189 0.296
dendrite development GO:0016358 115 0.295
covalent chromatin modification GO:0016569 163 0.294
regulation of cellular amine metabolic process GO:0033238 20 0.291
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.290
Yeast Mouse
intracellular protein transport GO:0006886 204 0.286
Yeast Rat
muscle tissue development GO:0060537 308 0.283
peptidyl serine modification GO:0018209 83 0.282
regulation of cellular catabolic process GO:0031329 242 0.277
Fly
intra s dna damage checkpoint GO:0031573 4 0.276
membrane organization GO:0061024 245 0.273
regulation of protein transport GO:0051223 163 0.266
Yeast
autophagy GO:0006914 45 0.265
Fly
regulation of map kinase activity GO:0043405 120 0.263
negative regulation of molecular function GO:0044092 258 0.261
Yeast Mouse
protein autophosphorylation GO:0046777 61 0.258
Yeast
erk1 and erk2 cascade GO:0070371 77 0.257
Human Fly
organ or tissue specific immune response GO:0002251 13 0.252
placenta development GO:0001890 140 0.247
regulation of neuron differentiation GO:0045664 281 0.244
Fly
regulation of intracellular protein transport GO:0033157 82 0.242
Yeast
stress activated mapk cascade GO:0051403 80 0.240
Fly
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.240
regulation of protein kinase activity GO:0045859 232 0.239
regulation of nucleocytoplasmic transport GO:0046822 73 0.237
Yeast
protein import into nucleus GO:0006606 95 0.235
Rat
histone acetylation GO:0016573 41 0.233
chromatin organization GO:0006325 206 0.228
adherens junction maintenance GO:0034334 1 0.228
Fly
protein acylation GO:0043543 64 0.224
oocyte development GO:0048599 33 0.221
Worm
negative regulation of cellular protein metabolic process GO:0032269 247 0.210
peptidyl lysine modification GO:0018205 77 0.207
activation of immune response GO:0002253 138 0.205
protein targeting GO:0006605 143 0.201
Rat
i kappab kinase nf kappab signaling GO:0007249 85 0.201
cell fate commitment GO:0045165 210 0.198
negative regulation of protein metabolic process GO:0051248 282 0.197
peptidyl threonine modification GO:0018210 31 0.194
innate immune response GO:0045087 157 0.192
response to molecule of bacterial origin GO:0002237 143 0.191
hyperosmotic response GO:0006972 4 0.191
stem cell differentiation GO:0048863 268 0.190
regulation of stress activated mapk cascade GO:0032872 69 0.188
cellular macromolecule catabolic process GO:0044265 206 0.186
macromolecule catabolic process GO:0009057 281 0.185
Worm
protein import GO:0017038 101 0.184
Rat
regulation of ras protein signal transduction GO:0046578 114 0.184
Fly
negative regulation of protein modification process GO:0031400 163 0.183
internal protein amino acid acetylation GO:0006475 42 0.182
protein catabolic process GO:0030163 221 0.180
Worm
positive regulation of protein modification process GO:0031401 299 0.180
Human
cell type specific apoptotic process GO:0097285 268 0.180
regulation of transposition GO:0010528 2 0.177
Yeast
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.176
positive regulation of intracellular protein transport GO:0090316 42 0.175
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.175
osmosensory signaling pathway GO:0007231 1 0.172
actin filament organization GO:0007015 113 0.170
p38mapk cascade GO:0038066 4 0.169
positive regulation of apoptotic process GO:0043065 217 0.165
peptidyl threonine phosphorylation GO:0018107 31 0.165
endodermal cell fate specification GO:0001714 4 0.164
regulation of inflammatory response GO:0050727 147 0.163
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.161
mitotic cell cycle GO:0000278 195 0.161
Worm Fly
regulation of histone modification GO:0031056 56 0.161
regulation of organelle organization GO:0033043 289 0.161
response to cadmium ion GO:0046686 8 0.160
Fly
nuclear transport GO:0051169 139 0.159
Yeast Rat
peptidyl serine phosphorylation GO:0018105 74 0.158
positive regulation of nervous system development GO:0051962 221 0.156
Fly
regulation of chromatin modification GO:1903308 57 0.154
cellular response to lipid GO:0071396 145 0.151
protein modification by small protein conjugation or removal GO:0070647 207 0.151
microtubule based process GO:0007017 236 0.148
translation GO:0006412 93 0.147
Rat
regulation of jnk cascade GO:0046328 62 0.146
regulation of autophagy GO:0010506 30 0.145
Fly
meiotic cell cycle GO:0051321 122 0.145
Worm
positive regulation of cell death GO:0010942 224 0.144
protein localization to organelle GO:0033365 185 0.144
Rat
response to metal ion GO:0010038 47 0.143
Fly
nuclear division GO:0000280 158 0.141
Fly
axonogenesis GO:0007409 274 0.140
phagocytosis GO:0006909 66 0.138
cellular homeostasis GO:0019725 240 0.138
response to reactive oxygen species GO:0000302 56 0.138
Fly
macroautophagy GO:0016236 21 0.137
Fly
actin cytoskeleton organization GO:0030036 220 0.134
regulation of protein targeting GO:1903533 61 0.133
ras protein signal transduction GO:0007265 77 0.133
Worm Fly
response to osmotic stress GO:0006970 21 0.132
organonitrogen compound biosynthetic process GO:1901566 192 0.131
central nervous system projection neuron axonogenesis GO:0021952 21 0.130
regulation of epithelial cell proliferation GO:0050678 141 0.127
germ cell development GO:0007281 185 0.126
Worm
cellular response to osmotic stress GO:0071470 7 0.126
cellular response to inorganic substance GO:0071241 37 0.126
Fly
myeloid leukocyte differentiation GO:0002573 119 0.125
bmp signaling pathway GO:0030509 93 0.125
heterocycle catabolic process GO:0046700 280 0.124
skeletal system development GO:0001501 356 0.124
Mouse
negative regulation of immune system process GO:0002683 209 0.122
fat cell differentiation GO:0045444 160 0.121
synaptic transmission GO:0007268 329 0.120
Fly
synapse organization GO:0050808 125 0.119
myeloid cell differentiation GO:0030099 233 0.119
positive regulation of protein export from nucleus GO:0046827 4 0.119
Yeast
development of primary sexual characteristics GO:0045137 143 0.118
Worm
fatty acid metabolic process GO:0006631 121 0.118
negative regulation of transferase activity GO:0051348 85 0.116
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.116
epithelial cell proliferation GO:0050673 174 0.115
regulation of chromosome organization GO:0033044 83 0.115
cellular response to molecule of bacterial origin GO:0071219 83 0.114
nuclear import GO:0051170 95 0.112
Rat
oocyte maturation GO:0001556 18 0.112
Worm
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.111
Fly
female gamete generation GO:0007292 74 0.110
Worm
cellular response to extracellular stimulus GO:0031668 81 0.110
Fly
peptidyl lysine acetylation GO:0018394 45 0.108
regulation of actin filament based process GO:0032970 99 0.107
positive regulation of protein localization to nucleus GO:1900182 30 0.107
angiogenesis GO:0001525 201 0.107
digestive tract development GO:0048565 190 0.106
Zebrafish
cellular response to growth factor stimulus GO:0071363 197 0.105
protein localization to nucleus GO:0034504 121 0.105
Rat
regulation of cytoplasmic transport GO:1903649 112 0.105
Yeast
fatty acid derivative metabolic process GO:1901568 33 0.105
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.104
cellular response to starvation GO:0009267 57 0.104
Fly
positive regulation of apoptotic signaling pathway GO:2001235 95 0.104
regulation of translation GO:0006417 71 0.102
Rat
microglial cell activation GO:0001774 3 0.100
cellular response to lipopolysaccharide GO:0071222 77 0.100
connective tissue development GO:0061448 179 0.100
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.100
Worm
response to inorganic substance GO:0010035 96 0.100
Fly
response to peptide GO:1901652 136 0.099
positive regulation of nfat protein import into nucleus GO:0051533 1 0.099
response to interleukin 1 GO:0070555 11 0.099
cytoplasmic transport GO:0016482 234 0.099
Yeast Rat
pyrimidine containing compound metabolic process GO:0072527 11 0.098
negative regulation of kinase activity GO:0033673 81 0.098
negative regulation of ras protein signal transduction GO:0046580 18 0.097
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.096
purine nucleoside triphosphate catabolic process GO:0009146 203 0.096
digestive tract morphogenesis GO:0048546 147 0.095
Zebrafish
cytokine mediated signaling pathway GO:0019221 115 0.094
lateral inhibition GO:0046331 1 0.091
gland development GO:0048732 330 0.090
positive regulation of protein phosphorylation GO:0001934 242 0.090
Human
response to arsenic containing substance GO:0046685 5 0.090
Fly
protein export from nucleus GO:0006611 20 0.087
Yeast
central nervous system neuron differentiation GO:0021953 162 0.086
modification dependent protein catabolic process GO:0019941 133 0.085
response to nutrient levels GO:0031667 109 0.085
Fly
cellular protein catabolic process GO:0044257 155 0.085
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.085
Worm
t cell receptor signaling pathway GO:0050852 46 0.084
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.084
negative regulation of cell cycle GO:0045786 123 0.084
Yeast Worm
regulation of cytoskeleton organization GO:0051493 122 0.084
response to epidermal growth factor GO:0070849 4 0.083
Human
positive regulation of histone modification GO:0031058 28 0.083
engulfment of apoptotic cell GO:0043652 3 0.083
regulation of response to wounding GO:1903034 189 0.082
Fly
regulation of transferase activity GO:0051338 263 0.082
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.080
cellular response to nutrient levels GO:0031669 64 0.080
Fly
inflammatory response GO:0006954 244 0.080
apoptotic mitochondrial changes GO:0008637 48 0.080
response to drug GO:0042493 75 0.079
Fly
regulation of protein catabolic process GO:0042176 108 0.078
oogenesis GO:0048477 56 0.078
Worm
peptidyl tyrosine modification GO:0018212 145 0.076
neuron apoptotic process GO:0051402 142 0.075
canonical wnt signaling pathway GO:0060070 130 0.075
wnt signaling pathway GO:0016055 188 0.075
regulation of proteasomal protein catabolic process GO:0061136 46 0.074
cellular response to biotic stimulus GO:0071216 92 0.074
labyrinthine layer development GO:0060711 49 0.074
nuclear export GO:0051168 34 0.073
Yeast
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.073
leukocyte differentiation GO:0002521 342 0.073
positive regulation of protein import into nucleus GO:0042307 26 0.073
dna metabolic process GO:0006259 303 0.071
placenta blood vessel development GO:0060674 31 0.071
ion transmembrane transport GO:0034220 361 0.070
cell adhesion GO:0007155 329 0.069
regulation of proteolysis GO:0030162 164 0.069
cellular ion homeostasis GO:0006873 165 0.069
negative regulation of cell proliferation GO:0008285 296 0.069
mitotic nuclear division GO:0007067 48 0.068
Fly
aromatic compound catabolic process GO:0019439 286 0.068
labyrinthine layer blood vessel development GO:0060716 21 0.068
response to nitrosative stress GO:0051409 1 0.067
regulation of embryonic development GO:0045995 71 0.067
rho protein signal transduction GO:0007266 32 0.067
proteasomal protein catabolic process GO:0010498 98 0.066
regulation of cellular protein catabolic process GO:1903362 61 0.066
negative regulation of mitotic cell cycle GO:0045930 58 0.066
Worm
regulation of mitochondrial membrane permeability GO:0046902 17 0.065
regulation of jun kinase activity GO:0043506 40 0.064
central nervous system neuron axonogenesis GO:0021955 28 0.064
organophosphate biosynthetic process GO:0090407 122 0.063
locomotory behavior GO:0007626 195 0.063
rna 3 end processing GO:0031123 20 0.063
defense response to other organism GO:0098542 197 0.062
positive regulation of chromosome organization GO:2001252 33 0.062
unsaturated fatty acid metabolic process GO:0033559 31 0.062
calcium ion transport GO:0006816 159 0.061
cation transport GO:0006812 399 0.061
single organism cell adhesion GO:0098602 156 0.061
peptidyl tyrosine dephosphorylation GO:0035335 23 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.060
regulation of cell cycle process GO:0010564 160 0.060
regulation of response to drug GO:2001023 2 0.059
Fly
regulation of protein localization GO:0032880 231 0.059
Yeast
nucleoside metabolic process GO:0009116 246 0.059
developmental maturation GO:0021700 193 0.058
Worm
response to alcohol GO:0097305 48 0.058
Fly
cation homeostasis GO:0055080 212 0.058
glycerolipid metabolic process GO:0046486 122 0.058
spermatogenesis GO:0007283 284 0.058
maintenance of location GO:0051235 89 0.057
single organism nuclear import GO:1902593 95 0.057
Rat
response to heat GO:0009408 27 0.057
regulation of cellular component biogenesis GO:0044087 181 0.057
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.057
adult behavior GO:0030534 135 0.056
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.056
Rat
cytokine production GO:0001816 319 0.056
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.056
protein ubiquitination GO:0016567 171 0.056
central nervous system neuron development GO:0021954 67 0.056
striated muscle tissue development GO:0014706 293 0.056
skeletal muscle organ development GO:0060538 163 0.056
stem cell development GO:0048864 219 0.056
regulation of ion transport GO:0043269 215 0.055
organelle fission GO:0048285 170 0.055
Fly
endocytosis GO:0006897 168 0.055
protein modification by small protein conjugation GO:0032446 187 0.055
regulation of endopeptidase activity GO:0052548 89 0.055
cellular response to oxidative stress GO:0034599 76 0.055
Fly
protein processing GO:0016485 163 0.055
microtubule cytoskeleton organization GO:0000226 157 0.054
negative regulation of cell cycle phase transition GO:1901988 48 0.054
single organismal cell cell adhesion GO:0016337 131 0.053
positive regulation of protein kinase activity GO:0045860 144 0.053
response to extracellular stimulus GO:0009991 127 0.053
Fly
negative regulation of defense response GO:0031348 77 0.053
purine nucleoside metabolic process GO:0042278 241 0.052
gonad development GO:0008406 141 0.052
Worm
cellular response to organonitrogen compound GO:0071417 145 0.051
regulation of mitotic cell cycle phase transition GO:1901990 73 0.051
regulation of cellular component size GO:0032535 121 0.051
digestive system development GO:0055123 200 0.051
Zebrafish
regulation of protein autophosphorylation GO:0031952 8 0.051
myeloid leukocyte activation GO:0002274 83 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.050
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.050
respiratory burst GO:0045730 8 0.049
regulation of chromatin organization GO:1902275 57 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
immune effector process GO:0002252 321 0.049
transforming growth factor beta2 production GO:0032906 2 0.048
positive regulation of proteolysis GO:0045862 85 0.048
regulation of neuron apoptotic process GO:0043523 122 0.048
interleukin 1 mediated signaling pathway GO:0070498 4 0.048
cellular chemical homeostasis GO:0055082 215 0.047
cell cycle checkpoint GO:0000075 47 0.047
extrinsic apoptotic signaling pathway GO:0097191 126 0.047
negative regulation of inflammatory response GO:0050728 61 0.047
negative regulation of neuron death GO:1901215 98 0.047
negative regulation of cellular component organization GO:0051129 194 0.046
regulation of membrane permeability GO:0090559 18 0.046
adaptive immune response GO:0002250 155 0.046
response to ethanol GO:0045471 18 0.046
Fly
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.045
regulation of transforming growth factor beta2 production GO:0032909 2 0.045
regulation of cellular response to growth factor stimulus GO:0090287 82 0.045
regulation of kinase activity GO:0043549 249 0.045
negative regulation of apoptotic signaling pathway GO:2001234 104 0.044
exocytosis GO:0006887 121 0.044
regulation of secretion GO:0051046 274 0.044
macrophage activation GO:0042116 27 0.043
myotube differentiation GO:0014902 105 0.043
inorganic ion transmembrane transport GO:0098660 234 0.043
positive regulation of cell development GO:0010720 237 0.043
Fly
peptidyl tyrosine phosphorylation GO:0018108 143 0.043
erbb signaling pathway GO:0038127 32 0.043
Human
muscle cell development GO:0055001 133 0.043
monocarboxylic acid metabolic process GO:0032787 191 0.043
regulation of meiotic cell cycle GO:0051445 34 0.042
Worm
cellular response to abiotic stimulus GO:0071214 56 0.042
regulation of cell migration GO:0030334 219 0.042
Rat
negative regulation of response to wounding GO:1903035 77 0.042
gastrulation GO:0007369 116 0.042
Zebrafish
homeostasis of number of cells GO:0048872 210 0.042
positive regulation of innate immune response GO:0045089 80 0.042
response to nitric oxide GO:0071731 4 0.042
ribonucleotide metabolic process GO:0009259 291 0.041
metal ion homeostasis GO:0055065 189 0.041
positive regulation of cell motility GO:2000147 116 0.041
Rat
negative regulation of cell cycle process GO:0010948 69 0.041
sensory perception GO:0007600 245 0.041
Mouse Rat
myeloid cell homeostasis GO:0002262 114 0.041
heart growth GO:0060419 45 0.040
response to organonitrogen compound GO:0010243 246 0.040
oocyte differentiation GO:0009994 35 0.040
Worm
maternal process involved in female pregnancy GO:0060135 32 0.040
ubiquitin dependent protein catabolic process GO:0006511 129 0.040
positive regulation of meiotic cell cycle GO:0051446 15 0.040
Worm
mammary gland epithelial cell proliferation GO:0033598 24 0.040
regulation of canonical wnt signaling pathway GO:0060828 82 0.040
ossification GO:0001503 216 0.039
divalent metal ion transport GO:0070838 172 0.039
icosanoid metabolic process GO:0006690 33 0.039
oxidation reduction process GO:0055114 342 0.039
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.039
nitrogen compound transport GO:0071705 271 0.039
male gamete generation GO:0048232 285 0.039
regulation of protein export from nucleus GO:0046825 11 0.039
Yeast
anatomical structure homeostasis GO:0060249 145 0.039
protein maturation GO:0051604 176 0.038
osteoclast differentiation GO:0030316 62 0.038
purine containing compound catabolic process GO:0072523 213 0.038
intrinsic apoptotic signaling pathway GO:0097193 132 0.038
calcium ion homeostasis GO:0055074 127 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
stem cell maintenance GO:0019827 130 0.036
regulation of adaptive immune response GO:0002819 90 0.036
chromosome segregation GO:0007059 48 0.036
gliogenesis GO:0042063 141 0.036
purine nucleotide biosynthetic process GO:0006164 65 0.036
cell fate specification GO:0001708 72 0.036
epithelium migration GO:0090132 63 0.036
positive regulation of cell migration GO:0030335 109 0.036
Rat
regulation of nuclear division GO:0051783 56 0.036
nucleoside catabolic process GO:0009164 206 0.035
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
second messenger mediated signaling GO:0019932 73 0.034
mucosal immune response GO:0002385 13 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
actin filament based movement GO:0030048 23 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
lymphocyte proliferation GO:0046651 164 0.033
muscle cell differentiation GO:0042692 261 0.033
immune response regulating signaling pathway GO:0002764 125 0.033
internal peptidyl lysine acetylation GO:0018393 42 0.032
pyrimidine nucleobase metabolic process GO:0006206 3 0.032
muscle system process GO:0003012 141 0.032
regulation of dna dependent dna replication GO:0090329 8 0.031
striated muscle cell development GO:0055002 125 0.031
regulation of histone acetylation GO:0035065 19 0.031
olfactory learning GO:0008355 2 0.031
regulation of cysteine type endopeptidase activity GO:2000116 65 0.031
photoreceptor cell differentiation GO:0046530 52 0.031
Fly
regulation of macroautophagy GO:0016241 12 0.031
Fly
methylation GO:0032259 134 0.030
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.030
heart contraction GO:0060047 93 0.030
cellular calcium ion homeostasis GO:0006874 119 0.030
leukocyte proliferation GO:0070661 172 0.030
regulation of cytokine production GO:0001817 266 0.030
cellularization GO:0007349 1 0.030
regulation of protein processing GO:0070613 96 0.030
mitochondrion organization GO:0007005 134 0.030
regulation of ion transmembrane transporter activity GO:0032412 54 0.030
purine containing compound metabolic process GO:0072521 311 0.029
regulation of actin polymerization or depolymerization GO:0008064 45 0.029
modification dependent macromolecule catabolic process GO:0043632 133 0.029
response to organic cyclic compound GO:0014070 198 0.029
genitalia development GO:0048806 37 0.029
Worm
neuron death GO:0070997 154 0.029
rna processing GO:0006396 105 0.029
regulation of wound healing GO:0061041 40 0.029
Fly
formation of primary germ layer GO:0001704 77 0.029
pole plasm assembly GO:0007315 2 0.029
cellular response to insulin stimulus GO:0032869 78 0.029
protein polymerization GO:0051258 57 0.029
response to radiation GO:0009314 165 0.028
compound eye development GO:0048749 1 0.028
endoderm formation GO:0001706 20 0.028
regeneration GO:0031099 38 0.028
basal protein localization GO:0045175 1 0.028
regulation of protein localization to nucleus GO:1900180 60 0.028
antigen receptor mediated signaling pathway GO:0050851 64 0.028
respiratory system development GO:0060541 190 0.028
regulation of anatomical structure size GO:0090066 178 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
positive regulation of secretion GO:0051047 130 0.028
cellular component maintenance GO:0043954 11 0.027
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.027
cellular response to carbohydrate stimulus GO:0071322 50 0.027
negative regulation of transposition GO:0010529 2 0.027
Yeast
nucleoside phosphate catabolic process GO:1901292 222 0.027
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.027
protein localization to chromosome centromeric region GO:0071459 1 0.027
regulation of nuclear cell cycle dna replication GO:0033262 2 0.027
positive regulation of ras protein signal transduction GO:0046579 13 0.026
Fly
cation transmembrane transport GO:0098655 266 0.026
positive regulation of dna templated transcription elongation GO:0032786 2 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
cell division GO:0051301 120 0.026
divalent inorganic cation homeostasis GO:0072507 138 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
wound healing GO:0042060 157 0.026
Fly
cell cycle g1 s phase transition GO:0044843 57 0.026
cellular response to peptide GO:1901653 92 0.026
regulation of exocytosis GO:0017157 61 0.026
asymmetric neuroblast division GO:0055059 1 0.026
production of molecular mediator involved in inflammatory response GO:0002532 21 0.026
muscle contraction GO:0006936 101 0.026
negative regulation of wnt signaling pathway GO:0030178 73 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.026
blastocyst development GO:0001824 80 0.026
positive regulation of ossification GO:0045778 47 0.025
cellular response to nitric oxide GO:0071732 4 0.025
regulation of neuron death GO:1901214 134 0.025
learning or memory GO:0007611 148 0.025
regulation of peptidyl lysine acetylation GO:2000756 22 0.025
cellular response to peptide hormone stimulus GO:0071375 92 0.025
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
positive regulation of cytokine production GO:0001819 174 0.025
regulation of transmembrane transport GO:0034762 128 0.025
regulation of ion transmembrane transport GO:0034765 119 0.025
organonitrogen compound catabolic process GO:1901565 264 0.024
negative regulation of respiratory burst involved in inflammatory response GO:0060266 1 0.024
meiotic cell cycle process GO:1903046 77 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
response to transforming growth factor beta GO:0071559 88 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
phospholipid metabolic process GO:0006644 87 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
regulation of cell motility GO:2000145 236 0.024
Rat

Mapk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org