|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.981
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.914
|
Yeast |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.892
|
Yeast |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.887
|
Yeast |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.868
|
Yeast |
|
|
cellular response to cadmium ion
|
GO:0071276 |
3 |
0.857
|
Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.825
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.825
|
Yeast |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.775
|
Yeast Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.724
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.675
|
Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.644
|
|
|
|
jun phosphorylation
|
GO:0007258 |
41 |
0.633
|
Fly |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.616
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.612
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.562
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.552
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.533
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.528
|
Human |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.496
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.483
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.472
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.465
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.454
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.431
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.430
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.427
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.421
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.407
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.404
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.403
|
Yeast |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.399
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.397
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.396
|
Human Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.395
|
Yeast |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.377
|
Rat |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.375
|
Yeast |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.374
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.372
|
Yeast |
|
|
regulation of brown fat cell differentiation
|
GO:0090335 |
5 |
0.371
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.356
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.349
|
Yeast Worm |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.345
|
Yeast Rat |
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.333
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.333
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.332
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.327
|
Yeast |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.322
|
Yeast |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.321
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.317
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.314
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.312
|
Fly |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.312
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.307
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.303
|
Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.302
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.298
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.296
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.296
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.295
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.294
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.291
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.290
|
Yeast Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.286
|
Yeast Rat |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.283
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.282
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.277
|
Fly |
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.276
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.273
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.266
|
Yeast |
|
|
autophagy
|
GO:0006914 |
45 |
0.265
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.263
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.261
|
Yeast Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.258
|
Yeast |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.257
|
Human Fly |
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.252
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.247
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.244
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.242
|
Yeast |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.240
|
Fly |
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.240
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.239
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.237
|
Yeast |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.235
|
Rat |
|
|
histone acetylation
|
GO:0016573 |
41 |
0.233
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.228
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
1 |
0.228
|
Fly |
|
|
protein acylation
|
GO:0043543 |
64 |
0.224
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.221
|
Worm |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.210
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.207
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.205
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.201
|
Rat |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.201
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.198
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.197
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.194
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.192
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.191
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.191
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.190
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.188
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.186
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.185
|
Worm |
|
|
protein import
|
GO:0017038 |
101 |
0.184
|
Rat |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.184
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.183
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.182
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.180
|
Worm |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.180
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.180
|
|
|
|
regulation of transposition
|
GO:0010528 |
2 |
0.177
|
Yeast |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.176
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.175
|
Yeast |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.175
|
|
|
|
osmosensory signaling pathway
|
GO:0007231 |
1 |
0.172
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.170
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.169
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.165
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.165
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.164
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.163
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.161
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.161
|
Worm Fly |
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.161
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.161
|
|
|
|
response to cadmium ion
|
GO:0046686 |
8 |
0.160
|
Fly |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.159
|
Yeast Rat |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.158
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.156
|
Fly |
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.154
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.151
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.151
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.148
|
|
|
|
translation
|
GO:0006412 |
93 |
0.147
|
Rat |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.146
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.145
|
Fly |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.145
|
Worm |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.144
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.144
|
Rat |
|
|
response to metal ion
|
GO:0010038 |
47 |
0.143
|
Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.141
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.140
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.138
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.138
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.138
|
Fly |
|
|
macroautophagy
|
GO:0016236 |
21 |
0.137
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.134
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.133
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.133
|
Worm Fly |
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.132
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.131
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.130
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.127
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.126
|
Worm |
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.126
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.126
|
Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.125
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.125
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.124
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.124
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.122
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.121
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.120
|
Fly |
|
|
synapse organization
|
GO:0050808 |
125 |
0.119
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.119
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.119
|
Yeast |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.118
|
Worm |
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.118
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.116
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.116
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.115
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.115
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.114
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.112
|
Rat |
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.112
|
Worm |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.111
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.110
|
Worm |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.110
|
Fly |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.108
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.107
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.107
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.107
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.106
|
Zebrafish |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.105
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.105
|
Rat |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.105
|
Yeast |
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
33 |
0.105
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.104
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.104
|
Fly |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.104
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.102
|
Rat |
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.100
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.100
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.100
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.100
|
Worm |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.100
|
Fly |
|
|
response to peptide
|
GO:1901652 |
136 |
0.099
|
|
|
|
positive regulation of nfat protein import into nucleus
|
GO:0051533 |
1 |
0.099
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.099
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.099
|
Yeast Rat |
|
|
pyrimidine containing compound metabolic process
|
GO:0072527 |
11 |
0.098
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.098
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.097
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.096
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.096
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.095
|
Zebrafish |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.094
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.091
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.090
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.090
|
Human |
|
|
response to arsenic containing substance
|
GO:0046685 |
5 |
0.090
|
Fly |
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.087
|
Yeast |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.086
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.085
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.085
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.085
|
|
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.085
|
Worm |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.084
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.084
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.084
|
Yeast Worm |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.084
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.083
|
Human |
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.083
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.083
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.082
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.082
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
11 |
0.080
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.080
|
Fly |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.080
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.080
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.079
|
Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.078
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.078
|
Worm |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.076
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.075
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.075
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.075
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.074
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.074
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.074
|
|
|
|
nuclear export
|
GO:0051168 |
34 |
0.073
|
Yeast |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.073
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.073
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.073
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.071
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.071
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.069
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.069
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.069
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.069
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.068
|
Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.068
|
|
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.068
|
|
|
|
response to nitrosative stress
|
GO:0051409 |
1 |
0.067
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.067
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.067
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.066
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.066
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.066
|
Worm |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.065
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.064
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
28 |
0.064
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.063
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.063
|
|
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.063
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.062
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.062
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.062
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.061
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.061
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.061
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
23 |
0.060
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.060
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.060
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.059
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.059
|
Yeast |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.059
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.058
|
Worm |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.058
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.058
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.058
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.058
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.057
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.057
|
Rat |
|
|
response to heat
|
GO:0009408 |
27 |
0.057
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.057
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.057
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.056
|
Fly |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.056
|
Rat |
|
|
cytokine production
|
GO:0001816 |
319 |
0.056
|
|
|
|
negative regulation of protein kinase activity by regulation of protein phosphorylation
|
GO:0044387 |
2 |
0.056
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.056
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.056
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.056
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.056
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.056
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.055
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.055
|
Fly |
|
|
endocytosis
|
GO:0006897 |
168 |
0.055
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.055
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.055
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.055
|
Fly |
|
|
protein processing
|
GO:0016485 |
163 |
0.055
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.054
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.054
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.053
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.053
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.053
|
Fly |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.053
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.052
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.052
|
Worm |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.051
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.051
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.051
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.051
|
Zebrafish |
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.051
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.050
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.050
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.050
|
|
|
|
respiratory burst
|
GO:0045730 |
8 |
0.049
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.049
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.049
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.049
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
2 |
0.048
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.048
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.048
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.048
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.047
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.047
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.047
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.047
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.047
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.046
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
18 |
0.046
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.046
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.046
|
Fly |
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
11 |
0.045
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.045
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.045
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.045
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.044
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.044
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.044
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.043
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.043
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.043
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.043
|
Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.043
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.043
|
Human |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.043
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.043
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.042
|
Worm |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.042
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.042
|
Rat |
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.042
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.042
|
Zebrafish |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.042
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.042
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.042
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.041
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.041
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.041
|
Rat |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.041
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.041
|
Mouse Rat |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.041
|
|
|
|
heart growth
|
GO:0060419 |
45 |
0.040
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.040
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.040
|
Worm |
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.040
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.040
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.040
|
Worm |
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.040
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.040
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.039
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.039
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.039
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.039
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.039
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.039
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.039
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
11 |
0.039
|
Yeast |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.039
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.038
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.038
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.038
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.038
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.037
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.037
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.036
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.036
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.036
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.036
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.036
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.036
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.036
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.036
|
Rat |
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.036
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.035
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.035
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.034
|
|
|
|
mucosal immune response
|
GO:0002385 |
13 |
0.034
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.034
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.033
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.033
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.033
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.033
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.033
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.032
|
|
|
|
pyrimidine nucleobase metabolic process
|
GO:0006206 |
3 |
0.032
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.032
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
8 |
0.031
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.031
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.031
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.031
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.031
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.031
|
Fly |
|
|
regulation of macroautophagy
|
GO:0016241 |
12 |
0.031
|
Fly |
|
|
methylation
|
GO:0032259 |
134 |
0.030
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.030
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.030
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.030
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.030
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.030
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.030
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.030
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.030
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.030
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.029
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.029
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.029
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.029
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.029
|
Worm |
|
|
neuron death
|
GO:0070997 |
154 |
0.029
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.029
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.029
|
Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.029
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.029
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.029
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.029
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.028
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.028
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.028
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.028
|
|
|
|
basal protein localization
|
GO:0045175 |
1 |
0.028
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.028
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.028
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.028
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.028
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.028
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.028
|
|
|
|
cellular component maintenance
|
GO:0043954 |
11 |
0.027
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.027
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.027
|
|
|
|
negative regulation of transposition
|
GO:0010529 |
2 |
0.027
|
Yeast |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.027
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.027
|
|
|
|
protein localization to chromosome centromeric region
|
GO:0071459 |
1 |
0.027
|
|
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
0.027
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.026
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.026
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.026
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.026
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.026
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.026
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.026
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.026
|
Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.026
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.026
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.026
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.026
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.026
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.026
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.026
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.026
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.026
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.025
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.025
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.025
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.025
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.025
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.025
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.025
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.025
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.025
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.025
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.025
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.024
|
|
|
|
negative regulation of respiratory burst involved in inflammatory response
|
GO:0060266 |
1 |
0.024
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.024
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.024
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.024
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.024
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.024
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.024
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.024
|
Rat |
