Mus musculus

145 known processes

Mecom

MDS1 and EVI1 complex locus

(Aliases: MGC184568,MGC183337,Mds1-Evi1,Evi1,D630039M04Rik,Znfpr1b1,Prdm3,Jbo,Mds,Mds1,Evi-1)

Mecom biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tendon cell differentiation GO:0035990 4 0.952
regulation of cellular ketone metabolic process GO:0010565 66 0.929
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.922
stem cell differentiation GO:0048863 268 0.889
Mouse Fly
auditory receptor cell fate determination GO:0042668 3 0.876
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.865
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.859
somitogenesis GO:0001756 69 0.855
deltoid tuberosity development GO:0035993 3 0.853
embryonic placenta development GO:0001892 98 0.818
axon guidance GO:0007411 141 0.803
epithelial tube morphogenesis GO:0060562 303 0.800
multicellular organism growth GO:0035264 161 0.781
hindbrain development GO:0030902 128 0.776
tendon formation GO:0035992 4 0.771
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.769
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.769
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.760
embryonic organ morphogenesis GO:0048562 276 0.757
Zebrafish
cardiac right ventricle formation GO:0003219 3 0.756
embryonic heart tube formation GO:0003144 1 0.751
morphogenesis of a polarized epithelium GO:0001738 37 0.746
mesoderm morphogenesis GO:0048332 64 0.724
appendage morphogenesis GO:0035107 149 0.707
limb morphogenesis GO:0035108 149 0.703
multicellular organismal response to stress GO:0033555 62 0.696
regulation of mast cell differentiation GO:0060375 3 0.693
positive regulation of keratinocyte proliferation GO:0010838 4 0.690
neuron projection guidance GO:0097485 141 0.685
forebrain development GO:0030900 302 0.670
cell fate specification GO:0001708 72 0.668
striated muscle tissue development GO:0014706 293 0.666
regulation of auditory receptor cell differentiation GO:0045607 4 0.659
leukocyte differentiation GO:0002521 342 0.654
aortic valve morphogenesis GO:0003180 4 0.652
intracellular distribution of mitochondria GO:0048312 1 0.649
mesenchyme development GO:0060485 152 0.648
astrocyte fate commitment GO:0060018 4 0.642
neuromuscular process GO:0050905 99 0.638
establishment or maintenance of monopolar cell polarity GO:0061339 8 0.631
negative regulation of synapse maturation GO:2000297 2 0.624
embryonic appendage morphogenesis GO:0035113 126 0.623
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.610
regulation of homeostatic process GO:0032844 182 0.601
bmp signaling pathway GO:0030509 93 0.600
regionalization GO:0003002 337 0.594
embryonic skeletal system development GO:0048706 120 0.593
Zebrafish
mitral valve morphogenesis GO:0003183 4 0.590
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.589
stem cell development GO:0048864 219 0.586
Mouse
covalent chromatin modification GO:0016569 163 0.582
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.579
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.579
ear morphogenesis GO:0042471 118 0.573
circulatory system process GO:0003013 197 0.573
regulation of exit from mitosis GO:0007096 1 0.572
cellular amine metabolic process GO:0044106 44 0.570
intracellular receptor signaling pathway GO:0030522 74 0.570
neural tube formation GO:0001841 108 0.566
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.564
Mouse
establishment of epithelial cell apical basal polarity GO:0045198 5 0.556
positive regulation of synaptic plasticity GO:0031915 4 0.549
mesoderm development GO:0007498 100 0.548
dentate gyrus development GO:0021542 14 0.545
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.539
regulation of stem cell maintenance GO:2000036 17 0.531
embryonic limb morphogenesis GO:0030326 126 0.530
learning or memory GO:0007611 148 0.507
muscle system process GO:0003012 141 0.506
chromatin modification GO:0016568 187 0.505
regulation of cellular amine metabolic process GO:0033238 20 0.494
regulation of binding GO:0051098 111 0.491
regulation of neuron projection development GO:0010975 169 0.491
Fly
negative regulation of cellular amine metabolic process GO:0033239 1 0.490
blood vessel morphogenesis GO:0048514 285 0.483
rhythmic process GO:0048511 174 0.483
forelimb morphogenesis GO:0035136 40 0.476
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.474
visceral serous pericardium development GO:0061032 2 0.474
pancreatic a cell fate commitment GO:0003326 2 0.467
transmembrane transport GO:0055085 412 0.465
regulation of ion transport GO:0043269 215 0.462
mitochondrion distribution GO:0048311 4 0.461
cell adhesion GO:0007155 329 0.456
placenta development GO:0001890 140 0.456
histone acetylation GO:0016573 41 0.456
regulation of stem cell differentiation GO:2000736 50 0.455
cation transport GO:0006812 399 0.455
mesenchyme morphogenesis GO:0072132 32 0.453
skeletal muscle organ development GO:0060538 163 0.450
mitral valve development GO:0003174 4 0.448
spinal cord development GO:0021510 81 0.445
regulation of cellular amino acid metabolic process GO:0006521 5 0.443
cellular response to inorganic substance GO:0071241 37 0.441
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.441
semaphorin plexin signaling pathway GO:0071526 21 0.439
lipid biosynthetic process GO:0008610 179 0.438
endocrine system development GO:0035270 98 0.431
cytokine production GO:0001816 319 0.431
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.424
chemotaxis GO:0006935 247 0.420
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.420
hindbrain morphogenesis GO:0021575 46 0.418
pancreatic pp cell fate commitment GO:0003329 2 0.418
cellular ketone metabolic process GO:0042180 84 0.415
paraxial mesoderm morphogenesis GO:0048340 10 0.413
diterpenoid biosynthetic process GO:0016102 7 0.413
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.403
intestinal epithelial structure maintenance GO:0060729 4 0.401
positive regulation of calcium mediated signaling GO:0050850 15 0.401
neural tube development GO:0021915 160 0.400
positive regulation of exit from mitosis GO:0031536 1 0.399
paraxial mesoderm development GO:0048339 18 0.399
diencephalon development GO:0021536 63 0.398
endocardial cushion to mesenchymal transition GO:0090500 5 0.398
response to growth factor GO:0070848 198 0.396
Mouse
neural crest cell differentiation GO:0014033 54 0.394
oxidation reduction process GO:0055114 342 0.393
Mouse
neural crest cell migration GO:0001755 32 0.390
regulation of cytokine production GO:0001817 266 0.390
regulation of system process GO:0044057 200 0.389
cardiac muscle cell differentiation GO:0055007 69 0.389
cellular lipid metabolic process GO:0044255 323 0.388
face development GO:0060324 38 0.387
g protein coupled receptor signaling pathway GO:0007186 243 0.382
transdifferentiation GO:0060290 1 0.381
carbohydrate homeostasis GO:0033500 128 0.378
morphogenesis of a branching epithelium GO:0061138 193 0.377
regulation of secretion by cell GO:1903530 249 0.376
multicellular organismal homeostasis GO:0048871 164 0.371
mesenchymal cell development GO:0014031 93 0.368
cerebral cortex development GO:0021987 86 0.365
regulation of chromatin modification GO:1903308 57 0.359
embryonic epithelial tube formation GO:0001838 130 0.359
negative regulation of cell proliferation GO:0008285 296 0.357
Fly
regulation of myeloid leukocyte differentiation GO:0002761 58 0.356
mesoderm formation GO:0001707 62 0.353
somite development GO:0061053 81 0.350
hemangioblast cell differentiation GO:0060217 1 0.349
digestive tract development GO:0048565 190 0.348
mitotic cell cycle GO:0000278 195 0.345
platelet morphogenesis GO:0036344 13 0.338
calcium ion transport GO:0006816 159 0.337
negative regulation of cell cycle GO:0045786 123 0.336
auditory receptor cell fate specification GO:0042667 1 0.335
neural tube closure GO:0001843 90 0.334
face morphogenesis GO:0060325 29 0.331
regulation of calcium mediated signaling GO:0050848 19 0.330
sclerotome development GO:0061056 4 0.329
angiogenesis GO:0001525 201 0.328
stem cell proliferation GO:0072089 117 0.327
formation of primary germ layer GO:0001704 77 0.323
myeloid cell differentiation GO:0030099 233 0.323
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.317
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.314
formation of radial glial scaffolds GO:0021943 4 0.314
amine metabolic process GO:0009308 45 0.313
mesodermal cell differentiation GO:0048333 22 0.313
pallium development GO:0021543 120 0.311
ear development GO:0043583 200 0.311
lymphocyte differentiation GO:0030098 242 0.307
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.306
cell proliferation involved in heart valve development GO:2000793 2 0.303
regulation of neural retina development GO:0061074 3 0.303
cellular response to calcium ion GO:0071277 14 0.300
positive regulation of epithelial cell proliferation GO:0050679 68 0.300
cardiac muscle cell apoptotic process GO:0010659 10 0.296
t cell differentiation GO:0030217 174 0.289
regulation of retina development in camera type eye GO:1902866 3 0.288
branching morphogenesis of an epithelial tube GO:0048754 159 0.286
pituitary gland development GO:0021983 38 0.285
segmentation GO:0035282 93 0.285
inner ear morphogenesis GO:0042472 101 0.285
tube formation GO:0035148 140 0.284
dna metabolic process GO:0006259 303 0.284
blastocyst formation GO:0001825 33 0.283
positive regulation of erythrocyte differentiation GO:0045648 11 0.283
cell fate commitment GO:0045165 210 0.282
Fly
hippocampus development GO:0021766 52 0.281
pancreatic pp cell differentiation GO:0003312 2 0.281
axonogenesis GO:0007409 274 0.280
cardiac ventricle morphogenesis GO:0003208 50 0.280
regulation of chromosome organization GO:0033044 83 0.279
cell activation involved in immune response GO:0002263 126 0.278
immune effector process GO:0002252 321 0.277
skeletal system development GO:0001501 356 0.276
Zebrafish
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.272
dendrite development GO:0016358 115 0.271
Fly
limbic system development GO:0021761 72 0.269
divalent inorganic cation transport GO:0072511 178 0.268
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.266
autonomic nervous system development GO:0048483 43 0.265
myelination GO:0042552 74 0.265
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.264
cognition GO:0050890 149 0.261
regulation of muscle tissue development GO:1901861 97 0.260
glial cell differentiation GO:0010001 131 0.259
cellular amino acid metabolic process GO:0006520 103 0.259
positive regulation of cell death GO:0010942 224 0.258
regulation of muscle cell apoptotic process GO:0010660 17 0.256
regulation of keratinocyte proliferation GO:0010837 15 0.256
body morphogenesis GO:0010171 45 0.256
circadian rhythm GO:0007623 114 0.255
associative learning GO:0008306 61 0.251
respiratory system development GO:0060541 190 0.249
regulation of cell cycle process GO:0010564 160 0.249
hexose metabolic process GO:0019318 98 0.248
forebrain generation of neurons GO:0021872 63 0.247
glucose homeostasis GO:0042593 128 0.244
cardiac chamber morphogenesis GO:0003206 93 0.244
organic hydroxy compound metabolic process GO:1901615 203 0.238
appendage development GO:0048736 166 0.237
regulation of bmp signaling pathway GO:0030510 60 0.237
head morphogenesis GO:0060323 34 0.236
erythrocyte maturation GO:0043249 6 0.235
regulation of leukocyte differentiation GO:1902105 159 0.234
cardiac ventricle development GO:0003231 83 0.234
adaptive immune response GO:0002250 155 0.233
cardiocyte differentiation GO:0035051 87 0.231
segment specification GO:0007379 15 0.229
positive regulation of programmed cell death GO:0043068 218 0.226
epithelial cell proliferation GO:0050673 174 0.226
regulation of organ morphogenesis GO:2000027 144 0.223
regulation of epithelial cell proliferation GO:0050678 141 0.223
regulation of stem cell proliferation GO:0072091 78 0.223
peptidyl amino acid modification GO:0018193 336 0.222
gland development GO:0048732 330 0.220
regulation of glucose metabolic process GO:0010906 60 0.220
cellular response to external stimulus GO:0071496 88 0.214
negative regulation of ossification GO:0030279 49 0.211
cytoplasmic transport GO:0016482 234 0.210
action potential GO:0001508 78 0.207
keratinocyte proliferation GO:0043616 21 0.207
ameboidal type cell migration GO:0001667 128 0.207
cellular response to growth factor stimulus GO:0071363 197 0.207
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.206
positive regulation of stem cell differentiation GO:2000738 23 0.205
positive regulation of homeostatic process GO:0032846 64 0.203
cell maturation GO:0048469 127 0.203
negative regulation of protein metabolic process GO:0051248 282 0.202
cartilage development GO:0051216 140 0.201
establishment or maintenance of cell polarity GO:0007163 86 0.201
muscle tissue development GO:0060537 308 0.197
cell cycle arrest GO:0007050 37 0.195
regulation of erythrocyte differentiation GO:0045646 23 0.194
regulation of organelle organization GO:0033043 289 0.193
internal protein amino acid acetylation GO:0006475 42 0.193
negative regulation of osteoblast differentiation GO:0045668 30 0.190
mesenchymal cell differentiation GO:0048762 107 0.187
mitochondrion organization GO:0007005 134 0.185
axial mesoderm development GO:0048318 8 0.184
anatomical structure homeostasis GO:0060249 145 0.183
primary neural tube formation GO:0014020 95 0.182
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.182
cerebellum development GO:0021549 77 0.182
definitive hemopoiesis GO:0060216 20 0.181
regulation of cardiac muscle tissue development GO:0055024 31 0.180
positive regulation of protein phosphorylation GO:0001934 242 0.180
ovulation cycle GO:0042698 59 0.178
alpha beta t cell activation GO:0046631 91 0.176
central nervous system neuron development GO:0021954 67 0.176
connective tissue development GO:0061448 179 0.175
trophectodermal cell differentiation GO:0001829 21 0.175
cell type specific apoptotic process GO:0097285 268 0.175
divalent metal ion transport GO:0070838 172 0.174
gastrulation GO:0007369 116 0.173
peptidyl lysine modification GO:0018205 77 0.173
cellular chemical homeostasis GO:0055082 215 0.173
parasympathetic nervous system development GO:0048486 19 0.172
locomotory behavior GO:0007626 195 0.171
platelet formation GO:0030220 12 0.171
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.171
developmental programmed cell death GO:0010623 41 0.170
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.169
neuromuscular process controlling posture GO:0050884 14 0.169
t cell activation GO:0042110 289 0.169
negative regulation of nervous system development GO:0051961 156 0.168
inner ear receptor cell differentiation GO:0060113 61 0.168
retinoic acid biosynthetic process GO:0002138 7 0.168
epithelial tube formation GO:0072175 130 0.167
homeostasis of number of cells GO:0048872 210 0.166
neural crest cell development GO:0014032 48 0.165
phenol containing compound biosynthetic process GO:0046189 21 0.164
nuclear division GO:0000280 158 0.164
negative regulation of jak stat cascade GO:0046426 7 0.163
camera type eye development GO:0043010 266 0.161
gliogenesis GO:0042063 141 0.161
leukocyte proliferation GO:0070661 172 0.160
mast cell differentiation GO:0060374 5 0.160
blastocyst development GO:0001824 80 0.160
neuron migration GO:0001764 122 0.160
erythrocyte differentiation GO:0030218 88 0.159
second messenger mediated signaling GO:0019932 73 0.158
cellular response to metal ion GO:0071248 31 0.158
cell fate determination GO:0001709 32 0.158
cardiac chamber development GO:0003205 108 0.157
response to inorganic substance GO:0010035 96 0.157
cell differentiation involved in embryonic placenta development GO:0060706 26 0.157
positive regulation of apoptotic process GO:0043065 217 0.157
digestion GO:0007586 40 0.156
lung development GO:0030324 164 0.156
neuron projection extension GO:1990138 64 0.156
thymus development GO:0048538 41 0.156
leukocyte migration GO:0050900 124 0.154
embryonic skeletal system morphogenesis GO:0048704 91 0.153
Zebrafish
b cell activation GO:0042113 161 0.152
negative regulation of myeloid cell differentiation GO:0045638 38 0.152
negative regulation of muscle cell apoptotic process GO:0010656 9 0.151
establishment of monopolar cell polarity GO:0061162 8 0.151
cellular response to bmp stimulus GO:0071773 14 0.150
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.150
fear response GO:0042596 33 0.150
b cell proliferation GO:0042100 53 0.150
calcium mediated signaling GO:0019722 46 0.149
polarity specification of proximal distal axis GO:0010085 2 0.149
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.149
Fly
kidney morphogenesis GO:0060993 83 0.149
extracellular matrix organization GO:0030198 147 0.149
response to calcium ion GO:0051592 20 0.148
extracellular structure organization GO:0043062 148 0.148
establishment of epithelial cell polarity GO:0090162 10 0.147
histone modification GO:0016570 159 0.147
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.146
negative regulation of cellular component organization GO:0051129 194 0.146
regulation of histone modification GO:0031056 56 0.146
regulation of mitosis GO:0007088 29 0.146
positive regulation of cell motility GO:2000147 116 0.145
limb development GO:0060173 166 0.145
respiratory tube development GO:0030323 167 0.145
multicellular organismal signaling GO:0035637 91 0.144
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.143
jak stat cascade GO:0007259 42 0.142
energy derivation by oxidation of organic compounds GO:0015980 77 0.141
Mouse
organ growth GO:0035265 117 0.141
cardiac muscle cell development GO:0055013 39 0.140
kidney development GO:0001822 213 0.139
mechanoreceptor differentiation GO:0042490 67 0.139
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.137
b cell differentiation GO:0030183 78 0.137
enteroendocrine cell differentiation GO:0035883 16 0.137
metencephalon development GO:0022037 89 0.136
pharynx development GO:0060465 1 0.135
regulation of lymphocyte activation GO:0051249 240 0.134
tissue homeostasis GO:0001894 115 0.134
regulation of mitotic cell cycle GO:0007346 126 0.133
heart formation GO:0060914 16 0.133
hematopoietic progenitor cell differentiation GO:0002244 143 0.133
peptide transport GO:0015833 133 0.132
endothelial cell differentiation GO:0045446 41 0.132
regulation of neuron differentiation GO:0045664 281 0.131
Worm Fly
labyrinthine layer development GO:0060711 49 0.131
organelle localization GO:0051640 179 0.131
embryonic heart tube development GO:0035050 65 0.129
amacrine cell differentiation GO:0035881 5 0.129
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.127
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.127
regulation of canonical wnt signaling pathway GO:0060828 82 0.126
skeletal system morphogenesis GO:0048705 203 0.126
Zebrafish
synapse organization GO:0050808 125 0.126
negative regulation of intracellular signal transduction GO:1902532 167 0.126
Human
mammary placode formation GO:0060596 4 0.124
heart morphogenesis GO:0003007 178 0.123
response to transforming growth factor beta GO:0071559 88 0.122
Mouse
regulation of cardiac muscle cell apoptotic process GO:0010665 9 0.120
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.120
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.120
positive regulation of nervous system development GO:0051962 221 0.120
central nervous system neuron differentiation GO:0021953 162 0.118
carbohydrate metabolic process GO:0005975 230 0.118
glial cell development GO:0021782 54 0.117
nephron morphogenesis GO:0072028 69 0.117
coronary vasculature morphogenesis GO:0060977 9 0.116
negative regulation of cytokine production GO:0001818 84 0.116
regulation of transmembrane transport GO:0034762 128 0.116
organonitrogen compound biosynthetic process GO:1901566 192 0.116
sinoatrial node cell differentiation GO:0060921 3 0.115
his purkinje system cell differentiation GO:0060932 2 0.115
catecholamine metabolic process GO:0006584 30 0.114
megakaryocyte differentiation GO:0030219 26 0.114
regulation of cell motility GO:2000145 236 0.114
Worm
chromatin organization GO:0006325 206 0.114
sympathetic nervous system development GO:0048485 22 0.113
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.112
Mouse
pancreas development GO:0031016 57 0.111
phenol containing compound metabolic process GO:0018958 60 0.111
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.111
neural precursor cell proliferation GO:0061351 121 0.111
protein modification by small protein conjugation GO:0032446 187 0.111
muscle cell development GO:0055001 133 0.110
mapk cascade GO:0000165 281 0.109
Human
pericardium development GO:0060039 16 0.109
positive regulation of cell division GO:0051781 31 0.109
transmission of nerve impulse GO:0019226 76 0.109
protein acylation GO:0043543 64 0.108
regulation of osteoblast differentiation GO:0045667 67 0.107
negative regulation of striated muscle cell apoptotic process GO:0010664 8 0.106
muscle cell apoptotic process GO:0010657 18 0.106
heart valve formation GO:0003188 10 0.106
epithelial to mesenchymal transition GO:0001837 47 0.106
stem cell maintenance GO:0019827 130 0.105
Mouse
muscle cell differentiation GO:0042692 261 0.105
spinal cord association neuron differentiation GO:0021527 14 0.105
neuronal action potential GO:0019228 54 0.105
endocrine pancreas development GO:0031018 29 0.105
oligodendrocyte differentiation GO:0048709 53 0.104
regulation of chromatin organization GO:1902275 57 0.104
organic hydroxy compound biosynthetic process GO:1901617 77 0.104
terpenoid biosynthetic process GO:0016114 7 0.104
notch signaling pathway GO:0007219 71 0.104
regulation of cell adhesion GO:0030155 154 0.103
regulation of transporter activity GO:0032409 57 0.103
tumor necrosis factor production GO:0032640 50 0.103
response to organonitrogen compound GO:0010243 246 0.102
blood circulation GO:0008015 195 0.102
positive regulation of lymphocyte activation GO:0051251 140 0.102
peptidyl lysine acetylation GO:0018394 45 0.101
negative regulation of dna binding GO:0043392 20 0.100
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.100
regulation of epithelial to mesenchymal transition GO:0010717 22 0.099
mitochondrion localization GO:0051646 9 0.099
response to extracellular stimulus GO:0009991 127 0.099
mesenchymal cell proliferation GO:0010463 44 0.099
cell recognition GO:0008037 83 0.099
organelle fission GO:0048285 170 0.097
regulation of membrane potential GO:0042391 192 0.097
regulation of cell cycle GO:0051726 281 0.097
Human
peroxisome proliferator activated receptor signaling pathway GO:0035357 9 0.096
endodermal cell fate specification GO:0001714 4 0.096
monosaccharide metabolic process GO:0005996 106 0.095
positive regulation of myeloid cell differentiation GO:0045639 43 0.095
response to metal ion GO:0010038 47 0.094
negative regulation of organelle organization GO:0010639 90 0.094
positive regulation of nuclear division GO:0051785 27 0.094
respiratory system process GO:0003016 25 0.093
mitotic cell cycle process GO:1903047 159 0.092
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.092
lymphocyte activation involved in immune response GO:0002285 93 0.092
single organism cell adhesion GO:0098602 156 0.092
regulation of cell projection organization GO:0031344 206 0.091
Fly
regulation of t cell activation GO:0050863 170 0.091
dorsal spinal cord development GO:0021516 20 0.091
odontogenesis of dentin containing tooth GO:0042475 66 0.090
generation of precursor metabolites and energy GO:0006091 103 0.090
Mouse
cell differentiation in spinal cord GO:0021515 53 0.089
morphogenesis of a branching structure GO:0001763 203 0.089
developmental maturation GO:0021700 193 0.089
striated muscle cell apoptotic process GO:0010658 12 0.089
sensory organ morphogenesis GO:0090596 242 0.089
glial cell fate commitment GO:0021781 14 0.089
urogenital system development GO:0001655 261 0.089
digestive tract morphogenesis GO:0048546 147 0.089
metanephros development GO:0001656 79 0.089
axon ensheathment GO:0008366 76 0.089
dna recombination GO:0006310 92 0.088
regulation of peptidyl lysine acetylation GO:2000756 22 0.088
hematopoietic stem cell differentiation GO:0060218 8 0.088
cellular response to extracellular stimulus GO:0031668 81 0.088
telencephalon development GO:0021537 186 0.087
ossification GO:0001503 216 0.087
anion transport GO:0006820 177 0.087
regulation of carbohydrate metabolic process GO:0006109 75 0.086
tube closure GO:0060606 91 0.086
single organismal cell cell adhesion GO:0016337 131 0.086
negative regulation of protein modification process GO:0031400 163 0.085
regulation of synapse maturation GO:0090128 9 0.085
myeloid leukocyte differentiation GO:0002573 119 0.084
peripheral nervous system neuron development GO:0048935 9 0.084
regulation of striated muscle cell apoptotic process GO:0010662 11 0.084
regulation of circadian rhythm GO:0042752 58 0.083
primitive hemopoiesis GO:0060215 7 0.083
regulation of nuclear division GO:0051783 56 0.082
somatic diversification of immune receptors GO:0002200 53 0.082
interferon gamma production GO:0032609 67 0.082
response to bmp GO:0071772 14 0.082
renal system development GO:0072001 225 0.081
formation of organ boundary GO:0010160 1 0.081
energy reserve metabolic process GO:0006112 39 0.081
cardioblast proliferation GO:0003263 8 0.081
leukocyte activation involved in immune response GO:0002366 126 0.081
regulation of cardiac chamber morphogenesis GO:1901219 2 0.081
organophosphate biosynthetic process GO:0090407 122 0.080
cardiac muscle tissue development GO:0048738 130 0.080
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.080
Mouse
regulation of semaphorin plexin signaling pathway GO:2001260 1 0.080
ion transmembrane transport GO:0034220 361 0.080
embryonic genitalia morphogenesis GO:0030538 4 0.080
protein modification by small protein conjugation or removal GO:0070647 207 0.079
alpha beta t cell differentiation GO:0046632 69 0.079
negative regulation of cellular protein metabolic process GO:0032269 247 0.078
establishment of apical basal cell polarity GO:0035089 7 0.078
fertilization GO:0009566 127 0.078
positive regulation of cell development GO:0010720 237 0.077
peptide secretion GO:0002790 114 0.077
negative regulation of muscle tissue development GO:1901862 20 0.077
cellular homeostasis GO:0019725 240 0.077
respiratory gaseous exchange GO:0007585 43 0.077
regulation of type b pancreatic cell apoptotic process GO:2000674 5 0.076

Mecom disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org