IMP

Process View

Mus musculus

14 genes annotated in mouse

establishment or maintenance of epithelial cell apical basal polarity

Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment or maintenance of epithelial cell apical basal polarity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "establishment or maintenance of epithelial cell apical basal polarity" (in gray)

Name	Description	Probability	Func Analog Organism
Vangl2	vang-like 2 (van gogh, Drosophila)	0.998
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.881	Fly
Pax6	paired box gene 6	0.836
Neurod1	neurogenic differentiation 1	0.698	Mouse
Crb2	crumbs homolog 2 (Drosophila)	0.693
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.466	Fly
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.427	Fly
Ret	ret proto-oncogene	0.412
Mecom	MDS1 and EVI1 complex locus	0.403
Cd151	CD151 antigen	0.395
Otx2	orthodenticle homolog 2 (Drosophila)	0.350
Neurod4	neurogenic differentiation 4	0.340	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.336
Gdnf	glial cell line derived neurotrophic factor	0.284
Neurog2	neurogenin 2	0.267	Mouse
Pdx1	pancreatic and duodenal homeobox 1	0.229
Itga3	integrin alpha 3	0.222
Atoh7	atonal homolog 7 (Drosophila)	0.214	Mouse
Vangl1	vang-like 1 (van gogh, Drosophila)	0.213	Mouse
Prph2	peripherin 2	0.197
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.194
Cask	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.173
Sox11	SRY-box containing gene 11	0.166
Emx2	empty spiracles homolog 2 (Drosophila)	0.166
Foxc2	forkhead box C2	0.157
T	brachyury	0.153
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.148
Irs2	insulin receptor substrate 2	0.145
Lmx1b	LIM homeobox transcription factor 1 beta	0.118	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.116
Wdr1	WD repeat domain 1	0.114
Phox2b	paired-like homeobox 2b	0.099
Ldb1	LIM domain binding 1	0.097
Lhx1	LIM homeobox protein 1	0.093	Mouse
Ptk7	PTK7 protein tyrosine kinase 7	0.092
Dab1	disabled homolog 1 (Drosophila)	0.090
Hand1	heart and neural crest derivatives expressed transcript 1	0.088	Mouse
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.088
Emx1	empty spiracles homolog 1 (Drosophila)	0.083
Shh	sonic hedgehog	0.082
Tcfap2a	transcription factor AP-2, alpha	0.080
Ptf1a	pancreas specific transcription factor, 1a	0.077	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.076
Ina	internexin neuronal intermediate filament protein, alpha	0.075
Pax3	paired box gene 3	0.073
Col4a3	collagen, type IV, alpha 3	0.072
Rac1	RAS-related C3 botulinum substrate 1	0.071
Arx	aristaless related homeobox	0.071
Wt1	Wilms tumor 1 homolog	0.064
Lhx9	LIM homeobox protein 9	0.061	Mouse
Ush1g	Usher syndrome 1G homolog (human)	0.060
Pou4f2	POU domain, class 4, transcription factor 2	0.058
Insm1	insulinoma-associated 1	0.057
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.055
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.053
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.052
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.047
Tlx3	T-cell leukemia, homeobox 3	0.045
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.044
Lhx3	LIM homeobox protein 3	0.043	Mouse
Gata6	GATA binding protein 6	0.043
Crb1	crumbs homolog 1 (Drosophila)	0.043	Mouse
Nkx3-2	NK3 homeobox 2	0.041
Srrm4	serine/arginine repetitive matrix 4	0.040
Pax2	paired box gene 2	0.038
Dlg3	discs, large homolog 3 (Drosophila)	0.036
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.036
Sox2	SRY-box containing gene 2	0.034
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.034
Snai1	snail homolog 1 (Drosophila)	0.033
Nkd1	naked cuticle 1 homolog (Drosophila)	0.033
Gsc	goosecoid homeobox	0.032
Mmp24	matrix metallopeptidase 24	0.031
Rag2	recombination activating gene 2	0.031
Vegfa	vascular endothelial growth factor A	0.031
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.030
Bmp4	bone morphogenetic protein 4	0.030
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.030
Wwtr1	WW domain containing transcription regulator 1	0.029
Myh10	myosin, heavy polypeptide 10, non-muscle	0.029
Kiss1r	KISS1 receptor	0.028
Myh9	myosin, heavy polypeptide 9, non-muscle	0.028
Smad2	MAD homolog 2 (Drosophila)	0.028
Gata1	GATA binding protein 1	0.027
Fzd1	frizzled homolog 1 (Drosophila)	0.027
Lamb1	laminin B1	0.027
Pou4f3	POU domain, class 4, transcription factor 3	0.027
Fgf8	fibroblast growth factor 8	0.026
Cdx2	caudal type homeobox 2	0.025
Zic2	zinc finger protein of the cerebellum 2	0.025
Nkx6-1	NK6 homeobox 1	0.025
Smad4	MAD homolog 4 (Drosophila)	0.024
Lhx6	LIM homeobox protein 6	0.024	Mouse
En1	engrailed 1	0.024
Onecut1	one cut domain, family member 1	0.024
Hoxa1	homeobox A1	0.024
Gbx2	gastrulation brain homeobox 2	0.023
Foxd1	forkhead box D1	0.023
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.023
Shank2	SH3/ankyrin domain gene 2	0.023
Actn4	actinin alpha 4	0.023
Evx1	even skipped homeotic gene 1 homolog	0.023
Tcf15	transcription factor 15	0.023
Msx1	homeobox, msh-like 1	0.023
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.022
Lep	leptin	0.022
Myf5	myogenic factor 5	0.021
Foxg1	forkhead box G1	0.021
Fgf17	fibroblast growth factor 17	0.021
Lamc1	laminin, gamma 1	0.021
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.021
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.020
Grm1	glutamate receptor, metabotropic 1	0.020
Lhx4	LIM homeobox protein 4	0.020	Mouse
Smad1	MAD homolog 1 (Drosophila)	0.019
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.019
Zic3	zinc finger protein of the cerebellum 3	0.019
Trim62	tripartite motif-containing 62	0.019
Fgfr1	fibroblast growth factor receptor 1	0.018
Magel2	melanoma antigen, family L, 2	0.017
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.017
Whrn	whirlin	0.017
Large	like-glycosyltransferase	0.017
Gnrhr	gonadotropin releasing hormone receptor	0.017
Prokr2	prokineticin receptor 2	0.017
Notch2	Notch gene homolog 2 (Drosophila)	0.017
Hoxd11	homeobox D11	0.017
Wnt6	wingless-related MMTV integration site 6	0.017
Parva	parvin, alpha	0.016
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.016
Timp1	tissue inhibitor of metalloproteinase 1	0.016
Tcf3	transcription factor 3	0.016
Adcy1	adenylate cyclase 1	0.016
Gpc3	glypican 3	0.016
Glipr2	GLI pathogenesis-related 2	0.015
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.015
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.015
Neurog3	neurogenin 3	0.015	Mouse
Nsf	N-ethylmaleimide sensitive fusion protein	0.015
Lrrc58	leucine rich repeat containing 58	0.014
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.014	Fly
Efna2	ephrin A2	0.014
Neurog1	neurogenin 1	0.014	Mouse
Prox1	prospero-related homeobox 1	0.014
Hoxd13	homeobox D13	0.014
Utf1	undifferentiated embryonic cell transcription factor 1	0.014
Flnc	filamin C, gamma	0.013
Pou3f4	POU domain, class 3, transcription factor 4	0.013
Pax9	paired box gene 9	0.013
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.013
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Irx2	Iroquois related homeobox 2 (Drosophila)	0.013
Masp1	mannan-binding lectin serine peptidase 1	0.013
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.013
Cul4a	cullin 4A	0.013
Kalrn	kalirin, RhoGEF kinase	0.013
Yap1	yes-associated protein 1	0.013
Fgf15	fibroblast growth factor 15	0.012
Cd4	CD4 antigen	0.012
Nhlh1	nescient helix loop helix 1	0.012	Mouse
Hes5	hairy and enhancer of split 5 (Drosophila)	0.012
Shox2	short stature homeobox 2	0.012
Tcf21	transcription factor 21	0.012
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.012
Fev	FEV (ETS oncogene family)	0.012
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.012
Hmga2	high mobility group AT-hook 2	0.012
Src	Rous sarcoma oncogene	0.012
Dact3	dapper homolog 3, antagonist of beta-catenin (xenopus)	0.012
Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	0.012
Tbx18	T-box18	0.012
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.012
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.011
Hif3a	hypoxia inducible factor 3, alpha subunit	0.011
Rgnef	Rho-guanine nucleotide exchange factor	0.011
Sim1	single-minded homolog 1 (Drosophila)	0.011
Plcg2	phospholipase C, gamma 2	0.011
Igfbpl1	insulin-like growth factor binding protein-like 1	0.011
Sox21	SRY-box containing gene 21	0.011
Cdh4	cadherin 4	0.011
Wwc1	WW, C2 and coiled-coil domain containing 1	0.011
Bcar1	breast cancer anti-estrogen resistance 1	0.011
Dlx1	distal-less homeobox 1	0.011
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.011
Hoxd1	homeobox D1	0.011
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.011
Prkcz	protein kinase C, zeta	0.011
Krt7	keratin 7	0.011
Hes2	hairy and enhancer of split 2 (Drosophila)	0.011
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.011
Tbx15	T-box 15	0.011
Mmp11	matrix metallopeptidase 11	0.011
Sav1	salvador homolog 1 (Drosophila)	0.011
Map4k5	mitogen-activated protein kinase kinase kinase kinase 5	0.011
Zfp598	zinc finger protein 598	0.010
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.010
Gcm1	glial cells missing homolog 1 (Drosophila)	0.010
Tbx2	T-box 2	0.010
Foxf1a	forkhead box F1a	0.010
Cit	citron	0.010
Tgif2	TGFB-induced factor homeobox 2	0.010
Tcfap2c	transcription factor AP-2, gamma	0.010
Ptk2	PTK2 protein tyrosine kinase 2	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.010
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.010
Ssbp3	single-stranded DNA binding protein 3	0.010
Padi3	peptidyl arginine deiminase, type III	0.010
Tal2	T-cell acute lymphocytic leukemia 2	0.010	Mouse
Nphs2	nephrosis 2 homolog, podocin (human)	0.010
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.010