Mus musculus

97 known processes

Mmp2

matrix metallopeptidase 2

(Aliases: Clg4a,GelA,MMP-2)

Mmp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular matrix organization GO:0030198 147 0.956
Mouse
regulation of removal of superoxide radicals GO:2000121 4 0.951
skeletal system development GO:0001501 356 0.933
multicellular organismal catabolic process GO:0044243 7 0.930
extracellular structure organization GO:0043062 148 0.923
Mouse
regulation of cellular response to oxidative stress GO:1900407 19 0.809
Mouse
skeletal system morphogenesis GO:0048705 203 0.792
bone development GO:0060348 120 0.784
Mouse
lung development GO:0030324 164 0.754
bone morphogenesis GO:0060349 78 0.694
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.689
collagen fibril organization GO:0030199 32 0.676
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.636
elastic fiber assembly GO:0048251 4 0.611
fat cell differentiation GO:0045444 160 0.598
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.569
small gtpase mediated signal transduction GO:0007264 97 0.567
removal of superoxide radicals GO:0019430 12 0.521
connective tissue development GO:0061448 179 0.511
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.498
regulation of peptidase activity GO:0052547 96 0.481
regulation of cell substrate adhesion GO:0010810 73 0.469
cellular response to superoxide GO:0071451 14 0.444
cartilage development GO:0051216 140 0.439
Mouse
cellular response to oxygen radical GO:0071450 14 0.437
regulation of cell adhesion GO:0030155 154 0.409
Rat
response to growth factor GO:0070848 198 0.374
negative regulation of cell adhesion GO:0007162 45 0.369
Rat
respiratory system development GO:0060541 190 0.368
regulation of cartilage development GO:0061035 44 0.365
response to oxygen radical GO:0000305 16 0.352
cell adhesion GO:0007155 329 0.351
Rat
regulation of biomineral tissue development GO:0070167 33 0.349
negative regulation of cell proliferation GO:0008285 296 0.342
chondrocyte differentiation GO:0002062 72 0.335
biomineral tissue development GO:0031214 64 0.331
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.330
respiratory tube development GO:0030323 167 0.329
embryonic skeletal system development GO:0048706 120 0.323
cellular response to growth factor stimulus GO:0071363 197 0.313
antibacterial peptide secretion GO:0002779 1 0.313
Mouse
digestive system development GO:0055123 200 0.302
Human
response to amino acid GO:0043200 37 0.302
response to oxidative stress GO:0006979 123 0.297
Mouse Rat
cell matrix adhesion GO:0007160 68 0.295
response to superoxide GO:0000303 16 0.295
ovarian follicle development GO:0001541 40 0.293
Rat
formation of primary germ layer GO:0001704 77 0.282
Human
defense response to gram positive bacterium GO:0050830 50 0.277
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.262
Mouse
growth plate cartilage development GO:0003417 14 0.256
Mouse
basement membrane organization GO:0071711 8 0.251
Mouse
endoderm formation GO:0001706 20 0.243
Human
sensory perception GO:0007600 245 0.236
actin cytoskeleton organization GO:0030036 220 0.236
oxidation reduction process GO:0055114 342 0.231
renal system development GO:0072001 225 0.231
endochondral bone morphogenesis GO:0060350 50 0.222
Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.218
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.206
head morphogenesis GO:0060323 34 0.200
ras protein signal transduction GO:0007265 77 0.197
cell substrate adhesion GO:0031589 130 0.194
superoxide metabolic process GO:0006801 27 0.193
glycoprotein metabolic process GO:0009100 116 0.188
digestive tract development GO:0048565 190 0.188
Human
odontogenesis GO:0042476 78 0.186
Mouse
development of primary female sexual characteristics GO:0046545 73 0.178
Rat
positive regulation of proteolysis GO:0045862 85 0.172
regulation of proteolysis GO:0030162 164 0.170
regulation of hydrolase activity GO:0051336 246 0.170
trabecula formation GO:0060343 24 0.169
antibacterial peptide biosynthetic process GO:0002780 2 0.168
Mouse
regulation of angiogenesis GO:0045765 81 0.166
multicellular organismal homeostasis GO:0048871 164 0.162
blood vessel morphogenesis GO:0048514 285 0.162
Rat
replacement ossification GO:0036075 26 0.159
Mouse
appendage morphogenesis GO:0035107 149 0.159
protein hydroxylation GO:0018126 4 0.150
regulation of cellular component biogenesis GO:0044087 181 0.147
chemotaxis GO:0006935 247 0.146
Zebrafish Mouse
positive regulation of bone remodeling GO:0046852 13 0.146
negative regulation of intracellular signal transduction GO:1902532 167 0.146
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.145
Rat
digestive tract morphogenesis GO:0048546 147 0.138
Human
regulation of neuron differentiation GO:0045664 281 0.137
ossification GO:0001503 216 0.135
development of primary sexual characteristics GO:0045137 143 0.132
Rat
regulation of mapk cascade GO:0043408 248 0.130
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.130
anatomical structure homeostasis GO:0060249 145 0.129
regulation of hormone levels GO:0010817 211 0.127
protein catabolic process GO:0030163 221 0.126
Mouse
endoderm development GO:0007492 45 0.125
Human
spinal cord development GO:0021510 81 0.121
astrocyte cell migration GO:0043615 3 0.120
lung saccule development GO:0060430 7 0.120
embryonic skeletal system morphogenesis GO:0048704 91 0.117
regulation of cellular response to growth factor stimulus GO:0090287 82 0.117
bone mineralization GO:0030282 54 0.116
Mouse
axonogenesis GO:0007409 274 0.115
Zebrafish
organelle assembly GO:0070925 177 0.114
nuclear transport GO:0051169 139 0.114
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.112
gonad development GO:0008406 141 0.106
Rat
positive regulation of cellular component biogenesis GO:0044089 94 0.106
bone resorption GO:0045453 38 0.105
cellular response to abiotic stimulus GO:0071214 56 0.104
positive regulation of bone resorption GO:0045780 13 0.104
sequestering of bmp in extracellular matrix GO:0035582 3 0.104
positive regulation of hydrolase activity GO:0051345 148 0.104
regulation of response to reactive oxygen species GO:1901031 9 0.103
myeloid leukocyte migration GO:0097529 57 0.102
Mouse
regulation of organelle organization GO:0033043 289 0.102
positive regulation of cell substrate adhesion GO:0010811 47 0.101
regulation of response to oxidative stress GO:1902882 19 0.100
Mouse
stem cell differentiation GO:0048863 268 0.100
trabecula morphogenesis GO:0061383 40 0.100
macromolecule catabolic process GO:0009057 281 0.100
Mouse
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.097
peptidyl amino acid modification GO:0018193 336 0.097
response to hypoxia GO:0001666 58 0.096
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.096
response to decreased oxygen levels GO:0036293 59 0.093
positive regulation of mapk cascade GO:0043410 170 0.092
sensory perception of mechanical stimulus GO:0050954 107 0.092
response to estrogen GO:0043627 24 0.092
Rat
signal transduction in absence of ligand GO:0038034 55 0.090
sensory organ morphogenesis GO:0090596 242 0.090
rho protein signal transduction GO:0007266 32 0.089
cellular component assembly involved in morphogenesis GO:0010927 139 0.088
regulation of cell migration GO:0030334 219 0.088
Mouse Rat
negative regulation of nervous system development GO:0051961 156 0.087
regulation of cell motility GO:2000145 236 0.087
Mouse Rat
tissue remodeling GO:0048771 102 0.086
Rat
sensory perception of sound GO:0007605 97 0.086
regulation of cytokine production GO:0001817 266 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.083
hormone secretion GO:0046879 128 0.081
ovulation cycle GO:0042698 59 0.080
Rat
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.080
ameboidal type cell migration GO:0001667 128 0.080
positive regulation of nervous system development GO:0051962 221 0.078
cardiac muscle tissue development GO:0048738 130 0.078
tissue migration GO:0090130 68 0.078
regulation of apoptotic signaling pathway GO:2001233 197 0.077
limb development GO:0060173 166 0.077
antimicrobial peptide secretion GO:0002776 1 0.076
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.076
response to transforming growth factor beta GO:0071559 88 0.075
regulation of bone mineralization GO:0030500 31 0.075
protein heterooligomerization GO:0051291 14 0.075
fibril organization GO:0097435 2 0.072
heart morphogenesis GO:0003007 178 0.071
negative regulation of molecular function GO:0044092 258 0.071
cellular response to organonitrogen compound GO:0071417 145 0.070
regulation of rho protein signal transduction GO:0035023 71 0.070
retina development in camera type eye GO:0060041 119 0.069
muscle tissue development GO:0060537 308 0.067
positive regulation of cell adhesion GO:0045785 80 0.067
protein processing GO:0016485 163 0.066
male gamete generation GO:0048232 285 0.066
regulation of tissue remodeling GO:0034103 38 0.066
regulation of actin cytoskeleton organization GO:0032956 84 0.066
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.065
collagen metabolic process GO:0032963 17 0.064
muscle cell development GO:0055001 133 0.064
epithelial cell proliferation GO:0050673 174 0.063
negative regulation of cartilage development GO:0061037 17 0.062
epithelial cell migration GO:0010631 63 0.061
response to organonitrogen compound GO:0010243 246 0.060
spermatogenesis GO:0007283 284 0.059
immune effector process GO:0002252 321 0.058
retinal ganglion cell axon guidance GO:0031290 18 0.058
Zebrafish
antimicrobial peptide biosynthetic process GO:0002777 2 0.058
Mouse
interspecies interaction between organisms GO:0044419 83 0.057
protein heterotrimerization GO:0070208 8 0.057
salivary gland development GO:0007431 37 0.056
face morphogenesis GO:0060325 29 0.056
response to thyroid hormone GO:0097066 2 0.056
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.056
protein maturation GO:0051604 176 0.055
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.055
inner ear morphogenesis GO:0042472 101 0.054
cell type specific apoptotic process GO:0097285 268 0.054
morphogenesis of embryonic epithelium GO:0016331 159 0.053
regulation of stem cell differentiation GO:2000736 50 0.053
cell chemotaxis GO:0060326 81 0.053
Mouse
limb morphogenesis GO:0035108 149 0.053
reactive oxygen species metabolic process GO:0072593 84 0.053
positive regulation of cell migration GO:0030335 109 0.052
Rat
exocrine system development GO:0035272 45 0.051
response to organic cyclic compound GO:0014070 198 0.050
Rat
response to inorganic substance GO:0010035 96 0.050
Rat
cellular response to acid chemical GO:0071229 68 0.049
tissue homeostasis GO:0001894 115 0.049
cytokine production GO:0001816 319 0.048
response to hyperoxia GO:0055093 2 0.048
Rat
single organism cell adhesion GO:0098602 156 0.048
detection of abiotic stimulus GO:0009582 60 0.048
positive regulation of cell projection organization GO:0031346 95 0.047
face development GO:0060324 38 0.047
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.046
cell substrate adherens junction assembly GO:0007045 19 0.046
cardiocyte differentiation GO:0035051 87 0.046
negative regulation of cell substrate adhesion GO:0010812 16 0.046
neuron migration GO:0001764 122 0.045
muscle tissue morphogenesis GO:0060415 53 0.045
negative regulation of cell cycle GO:0045786 123 0.045
bone trabecula formation GO:0060346 9 0.044
regulation of cell projection organization GO:0031344 206 0.043
inflammatory response GO:0006954 244 0.043
response to radiation GO:0009314 165 0.043
Rat
endothelial cell migration GO:0043542 44 0.042
positive regulation of apoptotic process GO:0043065 217 0.042
Mouse Rat
positive regulation of neuron differentiation GO:0045666 141 0.042
retinal blood vessel morphogenesis GO:0061304 3 0.042
intracellular protein transport GO:0006886 204 0.042
purine containing compound metabolic process GO:0072521 311 0.042
cellular ketone metabolic process GO:0042180 84 0.042
endodermal cell differentiation GO:0035987 14 0.042
Human
positive regulation of cytokine production GO:0001819 174 0.041
mucopolysaccharide metabolic process GO:1903510 25 0.041
cell growth GO:0016049 130 0.041
kidney development GO:0001822 213 0.041
membrane protein proteolysis GO:0033619 10 0.041
regulation of ossification GO:0030278 112 0.041
cardiac muscle cell development GO:0055013 39 0.040
leukocyte chemotaxis GO:0030595 69 0.040
Mouse
nucleotide sugar metabolic process GO:0009225 4 0.040
sulfur compound metabolic process GO:0006790 100 0.040
skin development GO:0043588 220 0.040
mitotic nuclear division GO:0007067 48 0.040
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.039
positive regulation of peptidase activity GO:0010952 49 0.039
proteoglycan metabolic process GO:0006029 38 0.039
response to oxygen levels GO:0070482 62 0.039
protein import into nucleus GO:0006606 95 0.039
epithelial to mesenchymal transition GO:0001837 47 0.039
nucleotide metabolic process GO:0009117 332 0.039
protein localization to nucleus GO:0034504 121 0.038
glucose transport GO:0015758 56 0.038
negative regulation of gastrulation GO:2000542 3 0.038
regulation of establishment of protein localization GO:0070201 181 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
cholesterol homeostasis GO:0042632 44 0.037
negative regulation of apoptotic signaling pathway GO:2001234 104 0.037
endocrine process GO:0050886 39 0.037
regulation of actin filament based process GO:0032970 99 0.037
branching morphogenesis of an epithelial tube GO:0048754 159 0.037
cellular response to oxidative stress GO:0034599 76 0.037
Mouse
cell cell adhesion GO:0098609 41 0.036
mesodermal cell migration GO:0008078 4 0.036
negative regulation of hydrolase activity GO:0051346 71 0.036
regulation of endopeptidase activity GO:0052548 89 0.036
developmental maturation GO:0021700 193 0.036
positive regulation of programmed cell death GO:0043068 218 0.035
Mouse Rat
production of molecular mediator of immune response GO:0002440 103 0.035
Mouse
response to reactive oxygen species GO:0000302 56 0.035
Rat
cellular response to external stimulus GO:0071496 88 0.035
filopodium assembly GO:0046847 19 0.035
negative regulation of alcohol biosynthetic process GO:1902931 4 0.035
embryonic limb morphogenesis GO:0030326 126 0.035
tendon development GO:0035989 6 0.035
striated muscle tissue development GO:0014706 293 0.035
cellular response to thyroid hormone stimulus GO:0097067 1 0.034
positive regulation of tissue remodeling GO:0034105 19 0.034
positive regulation of phospholipase activity GO:0010518 3 0.034
gastrulation GO:0007369 116 0.034
Human
negative regulation of odontogenesis GO:0042483 3 0.034
bmp signaling pathway GO:0030509 93 0.033
cartilage condensation GO:0001502 18 0.033
endochondral bone growth GO:0003416 19 0.033
Mouse
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.033
mesonephric tubule morphogenesis GO:0072171 63 0.032
synapse organization GO:0050808 125 0.032
ventral spinal cord development GO:0021517 48 0.032
peptidyl tyrosine phosphorylation GO:0018108 143 0.032
regulation of bmp signaling pathway GO:0030510 60 0.032
regulation of organ morphogenesis GO:2000027 144 0.032
rhythmic process GO:0048511 174 0.032
Rat
lateral inhibition GO:0046331 1 0.032
killing by host of symbiont cells GO:0051873 11 0.031
regulation of response to wounding GO:1903034 189 0.031
negative regulation of immune system process GO:0002683 209 0.031
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
epithelial cell development GO:0002064 159 0.031
embryonic organ morphogenesis GO:0048562 276 0.031
mitotic cell cycle GO:0000278 195 0.031
negative regulation of proteolysis GO:0045861 74 0.030
aminoglycan metabolic process GO:0006022 34 0.030
single organismal cell cell adhesion GO:0016337 131 0.030
negative regulation of chondrocyte differentiation GO:0032331 13 0.030
camera type eye development GO:0043010 266 0.030
synapse assembly GO:0007416 56 0.030
defense response to other organism GO:0098542 197 0.030
Mouse
ribose phosphate metabolic process GO:0019693 291 0.030
protein localization to membrane GO:0072657 108 0.030
regulation of cellular response to stress GO:0080135 159 0.029
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.029
regulation of blood pressure GO:0008217 93 0.029
actomyosin structure organization GO:0031032 56 0.029
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.029
cellular response to bmp stimulus GO:0071773 14 0.029
glucose homeostasis GO:0042593 128 0.029
nuclear membrane organization GO:0071763 4 0.028
cardiac chamber development GO:0003205 108 0.028
ureteric bud development GO:0001657 94 0.028
mitotic cell cycle process GO:1903047 159 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
hydrogen peroxide metabolic process GO:0042743 16 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
establishment or maintenance of cell polarity GO:0007163 86 0.028
formation of radial glial scaffolds GO:0021943 4 0.028
localization within membrane GO:0051668 4 0.028
negative regulation of protein processing GO:0010955 79 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.027
negative regulation of protein maturation GO:1903318 79 0.027
cardiac chamber morphogenesis GO:0003206 93 0.027
regulation of muscle adaptation GO:0043502 31 0.027
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.027
cellular modified amino acid metabolic process GO:0006575 63 0.027
cellular amine metabolic process GO:0044106 44 0.027
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.027
negative regulation of bmp signaling pathway GO:0030514 35 0.027
heart trabecula formation GO:0060347 14 0.026
cardiac ventricle morphogenesis GO:0003208 50 0.026
adult behavior GO:0030534 135 0.026
axon guidance GO:0007411 141 0.026
Zebrafish
extracellular matrix assembly GO:0085029 12 0.026
regulation of morphogenesis of a branching structure GO:0060688 53 0.025
smooth muscle tissue development GO:0048745 22 0.025
striated muscle cell development GO:0055002 125 0.025
positive regulation of glucose transport GO:0010828 16 0.025
response to acid chemical GO:0001101 111 0.025
mesenchymal cell differentiation GO:0048762 107 0.024
transmembrane transport GO:0055085 412 0.024
positive regulation of fatty acid oxidation GO:0046321 4 0.024
chondrocyte development GO:0002063 24 0.024
negative regulation of mitotic cell cycle GO:0045930 58 0.024
tendon cell differentiation GO:0035990 4 0.024
cardiac ventricle development GO:0003231 83 0.024
actin polymerization or depolymerization GO:0008154 54 0.024
regulation of protein localization to nucleus GO:1900180 60 0.024
negative regulation of biomineral tissue development GO:0070168 11 0.024
positive regulation of kinase activity GO:0033674 155 0.024
blood vessel endothelial cell migration GO:0043534 23 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.024
embryonic appendage morphogenesis GO:0035113 126 0.023
cytoplasmic transport GO:0016482 234 0.023
innate immune response GO:0045087 157 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
positive regulation of lipid metabolic process GO:0045834 40 0.023
negative regulation of growth GO:0045926 99 0.023
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.023
endothelial cell proliferation GO:0001935 27 0.023
positive regulation of stem cell proliferation GO:2000648 59 0.023
regulation of superoxide metabolic process GO:0090322 8 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
Rat
organelle fission GO:0048285 170 0.023
positive regulation of synaptic plasticity GO:0031915 4 0.023
regulation of cytoskeleton organization GO:0051493 122 0.022
regulation of protein catabolic process GO:0042176 108 0.022
regulation of neuron migration GO:2001222 22 0.022
regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000165 1 0.022
positive regulation of phospholipase c activity GO:0010863 2 0.022
meiotic nuclear division GO:0007126 115 0.022
regulation of protein processing GO:0070613 96 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
meiotic cell cycle GO:0051321 122 0.022
urogenital system development GO:0001655 261 0.022
Rat
negative regulation of multi organism process GO:0043901 68 0.022
response to nutrient levels GO:0031667 109 0.022
focal adhesion assembly GO:0048041 19 0.022
carbohydrate metabolic process GO:0005975 230 0.022
female sex differentiation GO:0046660 84 0.021
Rat
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.021
cytokine mediated signaling pathway GO:0019221 115 0.021
response to low density lipoprotein particle GO:0055098 2 0.021
positive regulation of transferase activity GO:0051347 167 0.021
negative regulation of prostatic bud formation GO:0060686 4 0.021
negative regulation of bone mineralization GO:0030502 10 0.021
negative regulation of macrophage chemotaxis GO:0010760 1 0.021
Mouse
establishment of protein localization to organelle GO:0072594 118 0.021
dendritic spine maintenance GO:0097062 4 0.021
mesenchymal epithelial cell signaling GO:0060638 9 0.021
regulation of homeostatic process GO:0032844 182 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
negative regulation of coagulation GO:0050819 11 0.020
regulation of system process GO:0044057 200 0.020
Rat
defense response to bacterium GO:0042742 119 0.020
Mouse
regulation of organ formation GO:0003156 34 0.020
bone remodeling GO:0046849 53 0.020
regulation of secretion by cell GO:1903530 249 0.020
positive regulation of protein transport GO:0051222 93 0.020
neural tube closure GO:0001843 90 0.020
adherens junction organization GO:0034332 28 0.020
regulation of cell cycle GO:0051726 281 0.019
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.019
nuclear import GO:0051170 95 0.019
peptide secretion GO:0002790 114 0.019
Mouse
response to erythropoietin GO:0036017 1 0.019
learning GO:0007612 98 0.019
female gonad development GO:0008585 71 0.019
Rat
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.019
cell recognition GO:0008037 83 0.019
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
palate development GO:0060021 76 0.019
positive regulation of bone mineralization GO:0030501 12 0.019
protein oligomerization GO:0051259 67 0.019
tyrosine phosphorylation of stat protein GO:0007260 23 0.019
response to steroid hormone GO:0048545 56 0.019
Rat
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.019
appendage development GO:0048736 166 0.019
positive regulation of cardioblast differentiation GO:0051891 3 0.019
steroid metabolic process GO:0008202 119 0.019
response to extracellular stimulus GO:0009991 127 0.019
mesoderm formation GO:0001707 62 0.019
nephron tubule morphogenesis GO:0072078 68 0.019
negative regulation of ossification GO:0030279 49 0.018
protein localization to organelle GO:0033365 185 0.018
male gonad development GO:0008584 88 0.018
cell fate specification GO:0001708 72 0.018
negative regulation of lipoprotein lipase activity GO:0051005 1 0.018
peptidyl proline hydroxylation GO:0019511 3 0.018
regulation of gastrulation GO:0010470 16 0.018
regulation of t cell proliferation GO:0042129 92 0.018
stem cell development GO:0048864 219 0.018
negative regulation of fibroblast proliferation GO:0048147 14 0.018
positive regulation of protein modification process GO:0031401 299 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
regulation of fat cell differentiation GO:0045598 81 0.018
Mouse
forebrain development GO:0030900 302 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
membrane protein ectodomain proteolysis GO:0006509 7 0.017
response to catecholamine GO:0071869 4 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
regulation of hormone secretion GO:0046883 88 0.017
craniofacial suture morphogenesis GO:0097094 10 0.017
antibacterial peptide production GO:0002778 2 0.017
Mouse
neuron apoptotic process GO:0051402 142 0.017
regulation of glucose transport GO:0010827 32 0.017
metanephric glomerulus morphogenesis GO:0072275 3 0.017
blood circulation GO:0008015 195 0.017
Rat
carbohydrate homeostasis GO:0033500 128 0.017
adherens junction assembly GO:0034333 22 0.017
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.017
plasma membrane organization GO:0007009 90 0.017
negative regulation of cell migration GO:0030336 59 0.017
Mouse
phospholipid metabolic process GO:0006644 87 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
Mouse
negative regulation of cardiac muscle tissue development GO:0055026 8 0.017
peptide metabolic process GO:0006518 46 0.017
Mouse
dna metabolic process GO:0006259 303 0.017
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.016
negative regulation of cell motility GO:2000146 61 0.016
Mouse
sensory perception of temperature stimulus GO:0050951 9 0.016
negative regulation of reproductive process GO:2000242 31 0.016

Mmp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.907
musculoskeletal system disease DOID:17 0 0.907
connective tissue disease DOID:65 0 0.907
bone development disease DOID:0080006 0 0.428
bone disease DOID:0080001 0 0.428
retinal disease DOID:5679 0 0.265
sensory system disease DOID:0050155 0 0.265
eye and adnexa disease DOID:1492 0 0.265
nervous system disease DOID:863 0 0.265
eye disease DOID:5614 0 0.265
muscular disease DOID:0080000 0 0.197
myopathy DOID:423 0 0.067
congenital muscular dystrophy DOID:0050557 0 0.067
muscular dystrophy DOID:9884 0 0.067
muscle tissue disease DOID:66 0 0.067
osteochondrodysplasia DOID:2256 0 0.054
retinal degeneration DOID:8466 0 0.053
osteogenesis imperfecta DOID:12347 0 0.052
bone remodeling disease DOID:0080005 0 0.027
heart disease DOID:114 0 0.026
cardiovascular system disease DOID:1287 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
osteoporosis DOID:11476 0 0.023
bone resorption disease DOID:0080011 0 0.023
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
neuropathy DOID:870 0 0.019
cardiomyopathy DOID:0050700 0 0.016
dilated cardiomyopathy DOID:12930 0 0.016
intrinsic cardiomyopathy DOID:0060036 0 0.016