IMP
Process View
lung saccule development
The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "lung saccule development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Shh | sonic hedgehog | 0.963 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.901 | Mouse | |
| Bmp4 | bone morphogenetic protein 4 | 0.696 | ||
| Sox9 | SRY-box containing gene 9 | 0.679 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.575 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.423 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.359 | ||
| Fgf8 | fibroblast growth factor 8 | 0.318 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.276 | ||
| Foxc2 | forkhead box C2 | 0.258 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.252 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.220 | Mouse | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.220 | ||
| Rarg | retinoic acid receptor, gamma | 0.210 | ||
| Jag1 | jagged 1 | 0.196 | ||
| Tbx1 | T-box 1 | 0.145 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.123 | ||
| Mmp2 | matrix metallopeptidase 2 | 0.120 | ||
| Idua | iduronidase, alpha-L- | 0.117 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.107 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.104 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.092 | ||
| Tcf21 | transcription factor 21 | 0.084 | ||
| Foxc1 | forkhead box C1 | 0.083 | ||
| Smo | smoothened homolog (Drosophila) | 0.077 | ||
| Gata6 | GATA binding protein 6 | 0.074 | ||
| Gata4 | GATA binding protein 4 | 0.065 | Mouse | |
| Vegfa | vascular endothelial growth factor A | 0.059 | ||
| Tbx3 | T-box 3 | 0.059 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.057 | ||
| Nog | noggin | 0.055 | ||
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.052 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.052 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.046 | ||
| Rxra | retinoid X receptor alpha | 0.042 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.042 | ||
| Hoxa1 | homeobox A1 | 0.040 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.035 | ||
| Fbn1 | fibrillin 1 | 0.033 | ||
| Lox | lysyl oxidase | 0.032 | ||
| Sox4 | SRY-box containing gene 4 | 0.030 | ||
| Npr2 | natriuretic peptide receptor 2 | 0.029 | ||
| Dek | DEK oncogene (DNA binding) | 0.028 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.026 | Mouse | |
| Tbx5 | T-box 5 | 0.026 | ||
| Sod3 | superoxide dismutase 3, extracellular | 0.025 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.025 | ||
| Sorbs3 | sorbin and SH3 domain containing 3 | 0.025 | ||
| Fgf10 | fibroblast growth factor 10 | 0.025 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.024 | ||
| Fbln5 | fibulin 5 | 0.024 | Mouse | |
| Pax2 | paired box gene 2 | 0.023 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.023 | ||
| Msx1 | homeobox, msh-like 1 | 0.022 | ||
| Mesp1 | mesoderm posterior 1 | 0.022 | ||
| Acvr1 | activin A receptor, type 1 | 0.021 | ||
| Pax3 | paired box gene 3 | 0.021 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.021 | ||
| Eln | elastin | 0.020 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.020 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.020 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.018 | ||
| Fgfrl1 | fibroblast growth factor receptor-like 1 | 0.017 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.017 | ||
| Tbx2 | T-box 2 | 0.017 | ||
| Meox2 | mesenchyme homeobox 2 | 0.017 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.016 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.016 | ||
| Npr3 | natriuretic peptide receptor 3 | 0.015 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.015 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.015 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.015 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.015 | ||
| Prrx1 | paired related homeobox 1 | 0.015 | ||
| Pcdh12 | protocadherin 12 | 0.015 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.014 | ||
| Foxe1 | forkhead box E1 | 0.014 | ||
| Fgf3 | fibroblast growth factor 3 | 0.014 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.014 | ||
| Nkx2-6 | NK2 transcription factor related, locus 6 (Drosophila) | 0.014 | Mouse | |
| Pthlh | parathyroid hormone-like peptide | 0.013 | ||
| Gja1 | gap junction protein, alpha 1 | 0.013 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.013 | ||
| Prrx2 | paired related homeobox 2 | 0.012 | ||
| Fbln1 | fibulin 1 | 0.012 | Mouse | |
| Col2a1 | collagen, type II, alpha 1 | 0.012 | ||
| Efnb2 | ephrin B2 | 0.011 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.011 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.011 | ||
| Hoxa13 | homeobox A13 | 0.011 | ||
| Mrc2 | mannose receptor, C type 2 | 0.011 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.011 | ||
| Nf1 | neurofibromatosis 1 | 0.010 |