|
|
dna metabolic process
|
GO:0006259 |
303 |
0.996
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.989
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.974
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.963
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.959
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.953
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.915
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.913
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.904
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.903
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.900
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.870
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.868
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.868
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.867
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.852
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.852
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.851
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.850
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.830
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.816
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.803
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.790
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.788
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.764
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.762
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.762
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.760
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.757
|
Mouse |
|
|
methylation
|
GO:0032259 |
134 |
0.754
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.751
|
Human Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.747
|
Human Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.745
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.741
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.741
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.737
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.731
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.729
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.727
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.721
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.701
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.698
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.696
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.694
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.693
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.676
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.672
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.671
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.663
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.648
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.632
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.624
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.619
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.615
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.612
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.611
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.598
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.591
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.586
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.586
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.585
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.581
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.566
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.566
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.565
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.564
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.559
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.539
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.533
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.533
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.530
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.528
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.522
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.522
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.516
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.514
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.512
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.512
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.509
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.509
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.506
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.505
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.501
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.500
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.496
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.483
|
|
|
|
regulation of dna methylation
|
GO:0044030 |
12 |
0.475
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.471
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.469
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.467
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.467
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.464
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.463
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.455
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.449
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.446
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.443
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.440
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.438
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.435
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.434
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.426
|
Human Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.420
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.414
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.407
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.406
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.405
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.404
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.404
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.404
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.403
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.403
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.402
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.401
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.398
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.395
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.391
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.389
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.388
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.387
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.385
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.384
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.382
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.382
|
Mouse |
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
20 |
0.381
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.381
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.380
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.379
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.377
|
Mouse |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.375
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.374
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.367
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.367
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.362
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.362
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.360
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.358
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.353
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.351
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.349
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.346
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.341
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.336
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.334
|
|
|
|
regulation of transcription during meiosis
|
GO:0051037 |
1 |
0.334
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.334
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.333
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.331
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.330
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.330
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.329
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.329
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.328
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.327
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.325
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.324
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.322
|
Human Mouse |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.322
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.320
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.319
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.319
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.317
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.316
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.315
|
Human Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.315
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.315
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.314
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.312
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.311
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.311
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.311
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.308
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.302
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.298
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.297
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.296
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.293
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.292
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.291
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.291
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.290
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.290
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.290
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.288
|
Mouse |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.288
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.286
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.284
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.283
|
|
|
|
positive regulation of atp biosynthetic process
|
GO:2001171 |
2 |
0.280
|
|
|
|
histone h3 k36 methylation
|
GO:0010452 |
6 |
0.280
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.279
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.277
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.275
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.274
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.273
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.272
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.271
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.270
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.269
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.268
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.266
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.266
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.261
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.261
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.260
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.257
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.256
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.254
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.254
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.254
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.253
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.252
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.251
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.250
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.249
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.249
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
22 |
0.248
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.247
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.247
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.245
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.244
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.244
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.243
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.242
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.242
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.241
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.240
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.239
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.239
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.238
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.237
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.236
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.236
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.236
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.235
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
4 |
0.235
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.234
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.234
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.233
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.232
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.232
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.229
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.229
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.229
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.228
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.227
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.223
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.223
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.223
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.222
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.221
|
Mouse |
|
|
lactation
|
GO:0007595 |
25 |
0.221
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.220
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.216
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.215
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.214
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.212
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.210
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.210
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
19 |
0.210
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.210
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.210
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.209
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.209
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.209
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.207
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.206
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.205
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.205
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.204
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.204
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.204
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.204
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.203
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.202
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.202
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.201
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.199
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.197
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.197
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.196
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.193
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.193
|
Human |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.192
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.192
|
|
|
|
neuron fate specification
|
GO:0048665 |
30 |
0.191
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.190
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.188
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.187
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.186
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.186
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.186
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.184
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.183
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
57 |
0.181
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.181
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.179
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.176
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.175
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.175
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.175
|
|
|
|
dna hypermethylation
|
GO:0044026 |
3 |
0.175
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.174
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.174
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.173
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.172
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.172
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.172
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.171
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.171
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.171
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.170
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.170
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.170
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.169
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.167
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.167
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.165
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902231 |
6 |
0.165
|
|
|
|
regulation of protein sumoylation
|
GO:0033233 |
4 |
0.164
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.163
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.163
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.162
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.161
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.161
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.160
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.158
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.157
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.157
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.156
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.155
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.155
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.155
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.154
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.154
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.153
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.153
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.153
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.153
|
|
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.153
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.153
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.152
|
Human Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.152
|
|
|
|
positive regulation of lipid storage
|
GO:0010884 |
10 |
0.151
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.150
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.150
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.149
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.148
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.147
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.145
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.145
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.145
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.145
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.144
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.144
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.144
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.143
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.143
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.142
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.141
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.140
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.140
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.140
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.140
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.139
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.139
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.139
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.139
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.138
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.138
|
|
|
|
smoothened signaling pathway involved in dorsal ventral neural tube patterning
|
GO:0060831 |
12 |
0.138
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.138
|
|
|
|
regulation of mammary gland involution
|
GO:1903519 |
4 |
0.137
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.136
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.136
|
|
|
|
mammary gland involution
|
GO:0060056 |
9 |
0.134
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.134
|
Mouse |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.134
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.134
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.133
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.133
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.133
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.132
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.131
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.131
|
|
|
|
positive regulation of triglyceride metabolic process
|
GO:0090208 |
9 |
0.131
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.131
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.131
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.131
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.131
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.130
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.129
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.129
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.129
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.129
|
|
|
|
histone h3 k9 trimethylation
|
GO:0036124 |
6 |
0.129
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.129
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.129
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.129
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.129
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.128
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.128
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.128
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.128
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.127
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.126
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.126
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
6 |
0.126
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.125
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.124
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.124
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.124
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.124
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.123
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.123
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.122
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.122
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
19 |
0.121
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.120
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.120
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.120
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.118
|
|
|
|
cellular response to prostaglandin stimulus
|
GO:0071379 |
2 |
0.117
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.117
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.117
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.117
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.115
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
18 |
0.114
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.114
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.114
|
|
|
|
luteinization
|
GO:0001553 |
8 |
0.114
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.113
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.112
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.112
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.112
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.111
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.111
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.110
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.110
|
|
|
|
response to ischemia
|
GO:0002931 |
14 |
0.110
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.109
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.109
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.109
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.109
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.108
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.108
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.108
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.108
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.106
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.105
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.105
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.104
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.104
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.104
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.104
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.103
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.103
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.103
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.102
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.102
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.102
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.102
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.101
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.100
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.100
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902229 |
14 |
0.099
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.097
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.097
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.096
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.096
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.096
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.096
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.096
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.096
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.095
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.095
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
48 |
0.095
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.093
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.093
|
|
|
|
positive regulation of protein sumoylation
|
GO:0033235 |
3 |
0.092
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.091
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.091
|
|
|
|
pigment cell differentiation
|
GO:0050931 |
27 |
0.091
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.091
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.091
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.090
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.090
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.090
|
|
|
|
dna packaging
|
GO:0006323 |
30 |
0.090
|
|
