Mus musculus

51 known processes

Nefh

neurofilament, heavy polypeptide

(Aliases: mKIAA0845,Nfh,NF200,NF-H)

Nefh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.381
Mouse
intermediate filament bundle assembly GO:0045110 3 0.284
schwann cell proliferation GO:0014010 2 0.219
Mouse
axon cargo transport GO:0008088 33 0.217
Mouse
ras protein signal transduction GO:0007265 77 0.184
ion transmembrane transport GO:0034220 361 0.181
regulation of neurotransmitter levels GO:0001505 87 0.181
Mouse
camera type eye development GO:0043010 266 0.179
Mouse
skeletal system development GO:0001501 356 0.172
neurofilament cytoskeleton organization GO:0060052 10 0.171
cation transport GO:0006812 399 0.170
nucleoside phosphate metabolic process GO:0006753 338 0.165
cation transmembrane transport GO:0098655 266 0.161
nitrogen compound transport GO:0071705 271 0.159
purine ribonucleoside metabolic process GO:0046128 241 0.155
purine ribonucleotide metabolic process GO:0009150 290 0.149
neuromuscular process GO:0050905 99 0.147
Mouse
regulation of schwann cell proliferation GO:0010624 2 0.137
Mouse
purine nucleotide metabolic process GO:0006163 302 0.136
regulation of hormone levels GO:0010817 211 0.131
nucleobase containing small molecule metabolic process GO:0055086 352 0.122
actin cytoskeleton organization GO:0030036 220 0.122
transmembrane transport GO:0055085 412 0.119
ribonucleotide catabolic process GO:0009261 208 0.117
neurotransmitter transport GO:0006836 76 0.108
Mouse
organophosphate catabolic process GO:0046434 232 0.104
oocyte construction GO:0007308 2 0.104
male meiosis GO:0007140 37 0.099
response to corticosterone GO:0051412 1 0.098
purine containing compound metabolic process GO:0072521 311 0.098
response to organonitrogen compound GO:0010243 246 0.096
intracellular protein transport GO:0006886 204 0.095
cellular amino acid metabolic process GO:0006520 103 0.095
ribose phosphate metabolic process GO:0019693 291 0.093
regulation of ion transport GO:0043269 215 0.091
amide transport GO:0042886 138 0.091
locomotory behavior GO:0007626 195 0.089
spermatogenesis GO:0007283 284 0.088
nucleoside triphosphate catabolic process GO:0009143 205 0.088
organic hydroxy compound metabolic process GO:1901615 203 0.088
anion transport GO:0006820 177 0.088
monosaccharide metabolic process GO:0005996 106 0.086
glial cell development GO:0021782 54 0.082
Mouse
cellular potassium ion transport GO:0071804 43 0.081
embryonic skeletal system development GO:0048706 120 0.079
nucleotide catabolic process GO:0009166 217 0.079
ribonucleotide metabolic process GO:0009259 291 0.078
purine ribonucleotide catabolic process GO:0009154 208 0.078
purine nucleoside triphosphate metabolic process GO:0009144 226 0.077
potassium ion transport GO:0006813 52 0.077
regulation of membrane potential GO:0042391 192 0.076
heterocycle catabolic process GO:0046700 280 0.076
regulation of neuron apoptotic process GO:0043523 122 0.075
Mouse
response to organic cyclic compound GO:0014070 198 0.075
amine metabolic process GO:0009308 45 0.074
inorganic cation transmembrane transport GO:0098662 207 0.074
meiotic nuclear division GO:0007126 115 0.074
sensory organ morphogenesis GO:0090596 242 0.072
glycosyl compound metabolic process GO:1901657 246 0.071
nucleotide metabolic process GO:0009117 332 0.070
negative regulation of cellular component organization GO:0051129 194 0.070
Mouse
cellular ketone metabolic process GO:0042180 84 0.068
hormone secretion GO:0046879 128 0.067
regulation of neurotransmitter transport GO:0051588 35 0.067
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.066
carboxylic acid transport GO:0046942 100 0.066
oocyte axis specification GO:0007309 2 0.066
purine nucleoside triphosphate catabolic process GO:0009146 203 0.064
sulfur compound metabolic process GO:0006790 100 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.064
purine nucleoside catabolic process GO:0006152 205 0.063
male gamete generation GO:0048232 285 0.063
microtubule based movement GO:0007018 84 0.061
Human Mouse
dna metabolic process GO:0006259 303 0.060
organelle fission GO:0048285 170 0.060
aromatic compound catabolic process GO:0019439 286 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.059
cellular response to cytokine stimulus GO:0071345 189 0.059
neurotransmitter secretion GO:0007269 62 0.059
regulation of neurotransmitter uptake GO:0051580 6 0.059
Mouse
establishment of vesicle localization GO:0051650 81 0.058
glycosyl compound catabolic process GO:1901658 206 0.057
regulation of vesicle mediated transport GO:0060627 139 0.057
ribonucleoside triphosphate metabolic process GO:0009199 220 0.057
regulation of organelle organization GO:0033043 289 0.056
pole plasm assembly GO:0007315 2 0.056
response to drug GO:0042493 75 0.056
cell type specific apoptotic process GO:0097285 268 0.056
Mouse
purine nucleotide catabolic process GO:0006195 211 0.056
steroid metabolic process GO:0008202 119 0.055
cellular calcium ion homeostasis GO:0006874 119 0.055
smad protein signal transduction GO:0060395 21 0.055
Mouse
negative regulation of neuron death GO:1901215 98 0.055
Mouse
nucleoside catabolic process GO:0009164 206 0.054
adult behavior GO:0030534 135 0.054
peripheral nervous system axon regeneration GO:0014012 2 0.053
Mouse
potassium ion transmembrane transport GO:0071805 43 0.053
exocytosis GO:0006887 121 0.052
hormone metabolic process GO:0042445 86 0.052
divalent metal ion transport GO:0070838 172 0.051
organic cyclic compound catabolic process GO:1901361 295 0.051
cell division GO:0051301 120 0.051
hexose metabolic process GO:0019318 98 0.051
neuromuscular process controlling balance GO:0050885 59 0.051
Mouse
regulation of protein kinase activity GO:0045859 232 0.051
cytoskeleton dependent intracellular transport GO:0030705 50 0.050
Human Mouse
inorganic ion transmembrane transport GO:0098660 234 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.049
cellular lipid metabolic process GO:0044255 323 0.049
microtubule based process GO:0007017 236 0.049
synaptic vesicle localization GO:0097479 59 0.048
positive regulation of protein phosphorylation GO:0001934 242 0.048
protein processing GO:0016485 163 0.048
asymmetric neuroblast division GO:0055059 1 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
adult locomotory behavior GO:0008344 91 0.047
meiotic cell cycle GO:0051321 122 0.047
negative regulation of protein metabolic process GO:0051248 282 0.047
regulation of hormone secretion GO:0046883 88 0.047
fertilization GO:0009566 127 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.046
cytoplasmic transport GO:0016482 234 0.045
protein maturation GO:0051604 176 0.045
epithelial cell development GO:0002064 159 0.045
Mouse
meiotic cell cycle process GO:1903046 77 0.044
neurotransmitter uptake GO:0001504 14 0.044
Mouse
peptide transport GO:0015833 133 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.043
positive regulation of necrotic cell death GO:0010940 1 0.043
peptide secretion GO:0002790 114 0.043
engulfment of apoptotic cell GO:0043652 3 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
embryonic organ morphogenesis GO:0048562 276 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
transmission of nerve impulse GO:0019226 76 0.041
potassium ion homeostasis GO:0055075 4 0.041
behavioral response to nutrient GO:0051780 1 0.041
intracellular mrna localization GO:0008298 4 0.040
regulation of secretion by cell GO:1903530 249 0.040
mitotic cell cycle process GO:1903047 159 0.040
regulation of proteolysis GO:0030162 164 0.040
peptidyl amino acid modification GO:0018193 336 0.039
regulation of synaptic plasticity GO:0048167 87 0.039
Mouse
carbohydrate metabolic process GO:0005975 230 0.039
ear development GO:0043583 200 0.038
peptide hormone secretion GO:0030072 109 0.038
leukocyte differentiation GO:0002521 342 0.038
gland development GO:0048732 330 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.037
intermediate filament based process GO:0045103 27 0.037
oxidation reduction process GO:0055114 342 0.037
calcium ion dependent exocytosis GO:0017156 35 0.037
regulation of fat cell differentiation GO:0045598 81 0.036
nuclear division GO:0000280 158 0.036
cellular amine metabolic process GO:0044106 44 0.035
myeloid leukocyte differentiation GO:0002573 119 0.035
nucleocytoplasmic transport GO:0006913 139 0.035
glycerolipid metabolic process GO:0046486 122 0.035
germ cell development GO:0007281 185 0.035
regulation of secretion GO:0051046 274 0.035
spermatid development GO:0007286 108 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
purine nucleoside metabolic process GO:0042278 241 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.034
spermatid differentiation GO:0048515 115 0.034
nucleoside monophosphate metabolic process GO:0009123 85 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
membrane tubulation GO:0097320 4 0.034
purine containing compound catabolic process GO:0072523 213 0.034
regulation of kinase activity GO:0043549 249 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
cellular homeostasis GO:0019725 240 0.033
regulation of peptide hormone secretion GO:0090276 75 0.033
negative regulation of neuron apoptotic process GO:0043524 92 0.033
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.033
glial cell differentiation GO:0010001 131 0.033
Mouse
regulation of response to drug GO:2001023 2 0.033
nucleoside metabolic process GO:0009116 246 0.033
bone development GO:0060348 120 0.033
regulation of metal ion transport GO:0010959 106 0.033
positive regulation of cell death GO:0010942 224 0.033
positive regulation of leukocyte differentiation GO:1902107 86 0.032
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
regulation of nucleoside metabolic process GO:0009118 130 0.030
eye photoreceptor cell differentiation GO:0001754 41 0.030
mapk cascade GO:0000165 281 0.030
macromolecule methylation GO:0043414 120 0.030
response to peptide GO:1901652 136 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
neuronal action potential GO:0019228 54 0.029
protein polymerization GO:0051258 57 0.029
vesicle transport along microtubule GO:0047496 9 0.029
reflex GO:0060004 22 0.029
regulation of gtp catabolic process GO:0033124 113 0.029
atp metabolic process GO:0046034 75 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
regulation of voltage gated calcium channel activity GO:1901385 4 0.029
membrane organization GO:0061024 245 0.028
positive regulation of protein modification process GO:0031401 299 0.028
regulation of peptide secretion GO:0002791 77 0.028
regulation of cell cycle GO:0051726 281 0.028
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.027
macromolecule catabolic process GO:0009057 281 0.027
substantia nigra development GO:0021762 2 0.027
insulin secretion GO:0030073 89 0.027
regulation of hydrolase activity GO:0051336 246 0.027
nuclear transport GO:0051169 139 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
maternal determination of anterior posterior axis embryo GO:0008358 2 0.027
respiratory tube development GO:0030323 167 0.027
bergmann glial cell differentiation GO:0060020 6 0.027
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
extracellular matrix organization GO:0030198 147 0.026
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.026
anatomical structure homeostasis GO:0060249 145 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
intermediate filament organization GO:0045109 15 0.026
appendage morphogenesis GO:0035107 149 0.026
regulation of cell migration GO:0030334 219 0.025
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
respiratory system development GO:0060541 190 0.025
regulation of transferase activity GO:0051338 263 0.025
regulation of lipid metabolic process GO:0019216 118 0.025
rho protein signal transduction GO:0007266 32 0.025
glucose metabolic process GO:0006006 92 0.025
oocyte differentiation GO:0009994 35 0.025
divalent inorganic cation homeostasis GO:0072507 138 0.025
divalent inorganic cation transport GO:0072511 178 0.025
immune effector process GO:0002252 321 0.025
multicellular organismal homeostasis GO:0048871 164 0.024
ossification GO:0001503 216 0.024
translation GO:0006412 93 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
fat cell differentiation GO:0045444 160 0.024
response to inorganic substance GO:0010035 96 0.024
negative regulation of cell projection organization GO:0031345 56 0.024
Mouse
defense response to other organism GO:0098542 197 0.024
positive regulation of transferase activity GO:0051347 167 0.024
cellular protein catabolic process GO:0044257 155 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
chemotaxis GO:0006935 247 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
negative regulation of molecular function GO:0044092 258 0.024
protein targeting GO:0006605 143 0.024
regulation of exocytosis GO:0017157 61 0.024
organic anion transport GO:0015711 137 0.023
oocyte anterior posterior axis specification GO:0007314 2 0.023
negative regulation of proteolysis GO:0045861 74 0.023
regulation of nucleocytoplasmic transport GO:0046822 73 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
female sex differentiation GO:0046660 84 0.023
actomyosin structure organization GO:0031032 56 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
development of primary sexual characteristics GO:0045137 143 0.023
positive regulation of glial cell proliferation GO:0060252 4 0.023
Mouse
organelle localization GO:0051640 179 0.023
long term synaptic potentiation GO:0060291 25 0.023
Mouse
nucleoside phosphate biosynthetic process GO:1901293 79 0.023
cellular protein complex assembly GO:0043623 116 0.023
protein ubiquitination GO:0016567 171 0.022
positive regulation of lymphocyte activation GO:0051251 140 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
regulation of ion transmembrane transport GO:0034765 119 0.022
activation of adenylate cyclase activity GO:0007190 4 0.022
atp catabolic process GO:0006200 55 0.022
cell maturation GO:0048469 127 0.022
regulation of neuron death GO:1901214 134 0.022
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
methylation GO:0032259 134 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
sensory perception of umami taste GO:0050917 4 0.021
photoreceptor cell differentiation GO:0046530 52 0.021
amino acid transport GO:0006865 61 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
Mouse
regulation of peptide transport GO:0090087 91 0.021
organic acid transport GO:0015849 101 0.021
establishment of synaptic vesicle localization GO:0097480 57 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
regulation of calcium ion transport GO:0051924 69 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
regulation of chloride transport GO:2001225 2 0.020
gtp metabolic process GO:0046039 144 0.020
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.020
skeletal system morphogenesis GO:0048705 203 0.020
digestive system development GO:0055123 200 0.020
rap protein signal transduction GO:0032486 3 0.020
habituation GO:0046959 3 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
multi organism behavior GO:0051705 62 0.020
single fertilization GO:0007338 82 0.020
positive regulation of nucleotide metabolic process GO:0045981 114 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
calcium ion transmembrane transport GO:0070588 85 0.019
response to mineralocorticoid GO:0051385 1 0.019
microtubule based transport GO:0010970 50 0.019
Human Mouse
endocrine system development GO:0035270 98 0.019
neuron neuron synaptic transmission GO:0007270 69 0.019
ribonucleotide biosynthetic process GO:0009260 59 0.019
carboxylic acid catabolic process GO:0046395 51 0.019
cellular chemical homeostasis GO:0055082 215 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
mitotic cell cycle GO:0000278 195 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
gonad development GO:0008406 141 0.019
heart process GO:0003015 94 0.019
osteoclast differentiation GO:0030316 62 0.019
epithelial cell proliferation GO:0050673 174 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.019
regulation of cell cycle process GO:0010564 160 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
adult walking behavior GO:0007628 41 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
alpha beta t cell differentiation GO:0046632 69 0.018
regulation of mapk cascade GO:0043408 248 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
eye photoreceptor cell development GO:0042462 31 0.018
response to steroid hormone GO:0048545 56 0.018
alcohol metabolic process GO:0006066 116 0.018
anion transmembrane transport GO:0098656 71 0.018
vesicle localization GO:0051648 86 0.018
lung development GO:0030324 164 0.018
skeletal muscle organ development GO:0060538 163 0.018
regulation of transmembrane transport GO:0034762 128 0.018
leukocyte migration GO:0050900 124 0.018
positive regulation of t cell activation GO:0050870 101 0.018
positive regulation of protein kinase activity GO:0045860 144 0.017
kidney development GO:0001822 213 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
vesicle organization GO:0016050 60 0.017
response to amphetamine GO:0001975 16 0.017
dna recombination GO:0006310 92 0.017
mitochondrion distribution GO:0048311 4 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
response to oxygen levels GO:0070482 62 0.017
compound eye development GO:0048749 1 0.017
cytokine mediated signaling pathway GO:0019221 115 0.017
positive regulation of cell development GO:0010720 237 0.017
Mouse
mrna metabolic process GO:0016071 84 0.017
endocytosis GO:0006897 168 0.017
rna interference GO:0016246 2 0.017
circulatory system process GO:0003013 197 0.017
regulation of protein processing GO:0070613 96 0.016
inorganic anion transport GO:0015698 43 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.016
synapsis GO:0007129 34 0.016
response to peptide hormone GO:0043434 127 0.016
calcium ion dependent exocytosis of neurotransmitter GO:0048791 7 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
regulation of protein localization GO:0032880 231 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
negative regulation of protein maturation GO:1903318 79 0.016
protein import into nucleus GO:0006606 95 0.016
regulation of neuron projection development GO:0010975 169 0.016
Mouse
ribonucleoside monophosphate catabolic process GO:0009158 57 0.016
macromolecule glycosylation GO:0043413 55 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.016
acid secretion GO:0046717 33 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
nucleotide biosynthetic process GO:0009165 78 0.016
phospholipid metabolic process GO:0006644 87 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
digestive tract development GO:0048565 190 0.016
l amino acid transport GO:0015807 32 0.016
cytokinetic process GO:0032506 2 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
immunoglobulin mediated immune response GO:0016064 69 0.015
negative regulation of nervous system development GO:0051961 156 0.015
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
palate development GO:0060021 76 0.015
chromatin organization GO:0006325 206 0.015
regulation of neurotransmitter secretion GO:0046928 29 0.015
chromatin modification GO:0016568 187 0.015
axonogenesis GO:0007409 274 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
gliogenesis GO:0042063 141 0.015
Mouse
small molecule catabolic process GO:0044282 71 0.015
peripheral nervous system development GO:0007422 53 0.015
apoptotic signaling pathway GO:0097190 306 0.015
plasma membrane organization GO:0007009 90 0.015
cellular response to peptide GO:1901653 92 0.015
astrocyte development GO:0014002 12 0.015
Mouse
organ growth GO:0035265 117 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
regulation of cell motility GO:2000145 236 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
regulation of organ growth GO:0046620 61 0.015
cerebellar purkinje cell differentiation GO:0021702 13 0.015
negative regulation of growth GO:0045926 99 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
protein catabolic process GO:0030163 221 0.015
nuclear export GO:0051168 34 0.015
erk1 and erk2 cascade GO:0070371 77 0.014
thymus development GO:0048538 41 0.014
cell chemotaxis GO:0060326 81 0.014
positive regulation of cell adhesion GO:0045785 80 0.014
second messenger mediated signaling GO:0019932 73 0.014
centrosome separation GO:0051299 4 0.014
extracellular structure organization GO:0043062 148 0.014
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.014
protein methylation GO:0006479 81 0.014
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.014
cell differentiation in spinal cord GO:0021515 53 0.014
developmental maturation GO:0021700 193 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
regulation of transporter activity GO:0032409 57 0.014
telencephalon development GO:0021537 186 0.014
regulation of protein maturation GO:1903317 96 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
response to histamine GO:0034776 1 0.014
negative regulation of protein processing GO:0010955 79 0.014
striated muscle tissue development GO:0014706 293 0.014
response to insulin GO:0032868 100 0.014
oocyte development GO:0048599 33 0.014
blood circulation GO:0008015 195 0.014
nucleobase containing compound transport GO:0015931 27 0.014
positive regulation of secretion GO:0051047 130 0.014
muscle system process GO:0003012 141 0.014
protein alkylation GO:0008213 81 0.014
regulation of chromosome organization GO:0033044 83 0.014
regulation of system process GO:0044057 200 0.014
organic acid catabolic process GO:0016054 51 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
negative regulation of organelle organization GO:0010639 90 0.014
calcium ion transport GO:0006816 159 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
stem cell development GO:0048864 219 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
regulation of peptidase activity GO:0052547 96 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
endoplasmic reticulum organization GO:0007029 10 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.013
neuron death GO:0070997 154 0.013
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.013
mitotic nuclear division GO:0007067 48 0.013
multicellular organismal response to stress GO:0033555 62 0.013
l alpha amino acid transmembrane transport GO:1902475 23 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.013
mesenchyme development GO:0060485 152 0.013
calcium ion homeostasis GO:0055074 127 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
positive regulation of peptide hormone secretion GO:0090277 31 0.013
regulation of cell projection organization GO:0031344 206 0.013
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
regulation of lyase activity GO:0051339 13 0.013
rna localization GO:0006403 23 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
lipid biosynthetic process GO:0008610 179 0.013
protein oligomerization GO:0051259 67 0.013
ribonucleoprotein complex disassembly GO:0032988 3 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
learning GO:0007612 98 0.013
negative regulation of neuron projection development GO:0010977 50 0.013
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
cholesterol metabolic process GO:0008203 56 0.013
digestive tract morphogenesis GO:0048546 147 0.013
response to osmotic stress GO:0006970 21 0.013
regulation of calcium ion transmembrane transport GO:1903169 20 0.013
endomembrane system organization GO:0010256 147 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.013
metal ion homeostasis GO:0055065 189 0.013
myeloid cell differentiation GO:0030099 233 0.012
forebrain development GO:0030900 302 0.012
lymphocyte differentiation GO:0030098 242 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
carbohydrate homeostasis GO:0033500 128 0.012
nuclear import GO:0051170 95 0.012
blood vessel morphogenesis GO:0048514 285 0.012
regulation of cellular component size GO:0032535 121 0.012
Mouse
t cell activation GO:0042110 289 0.012
striated muscle cell development GO:0055002 125 0.012

Nefh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.013