IMP

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Mus musculus

14 genes annotated in mouse

neurotransmitter uptake

The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. It does not occur during cholinergic synaptic transmission. Instead, acetylcholine is enzymatically degraded in the synaptic cleft.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neurotransmitter uptake"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neurotransmitter uptake" (in gray)

Name	Description	Probability	Func Analog Organism
Cry2	cryptochrome 2 (photolyase-like)	0.985
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.980
Per2	period homolog 2 (Drosophila)	0.790
Per1	period homolog 1 (Drosophila)	0.754	Mouse
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.752
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.700	Mouse
Slc12a1	solute carrier family 12, member 1	0.630
Clock	circadian locomotor output cycles kaput	0.615
Plp1	proteolipid protein (myelin) 1	0.583	Mouse
Nos1	nitric oxide synthase 1, neuronal	0.443
Ank1	ankyrin 1, erythroid	0.398
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.268
Cry1	cryptochrome 1 (photolyase-like)	0.233
Lepr	leptin receptor	0.168
Usp2	ubiquitin specific peptidase 2	0.148
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.146
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.126	Mouse
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.125
Nefl	neurofilament, light polypeptide	0.123	Mouse
Vdr	vitamin D receptor	0.123
Nefm	neurofilament, medium polypeptide	0.123	Mouse
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.107
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.105
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.105
Tef	thyrotroph embryonic factor	0.104
Drd2	dopamine receptor D2	0.097
Drd1a	dopamine receptor D1A	0.091
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.091
Ptgs2	prostaglandin-endoperoxide synthase 2	0.088
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.079
Per3	period homolog 3 (Drosophila)	0.078	Mouse
Esrrb	estrogen related receptor, beta	0.077
Nos3	nitric oxide synthase 3, endothelial cell	0.071	Mouse
Snca	synuclein, alpha	0.071	Human
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.068
Umod	uromodulin	0.068
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.066
Adra1a	adrenergic receptor, alpha 1a	0.063
Esr1	estrogen receptor 1 (alpha)	0.063
Mfn2	mitofusin 2	0.062
Ppt1	palmitoyl-protein thioesterase 1	0.061
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.058	Mouse
Ugt8a	UDP galactosyltransferase 8A	0.058
Osta	organic solute transporter alpha	0.057
Nphs2	nephrosis 2 homolog, podocin (human)	0.057
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.056
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.052
Slc22a8	solute carrier family 22 (organic anion transporter), member 8	0.051	Mouse
Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	0.051
Pparg	peroxisome proliferator activated receptor gamma	0.051
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.051	Mouse
Sh3gl2	SH3-domain GRB2-like 2	0.047
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.047
Hrh1	histamine receptor H1	0.046
Nefh	neurofilament, heavy polypeptide	0.044	Mouse
Pax8	paired box gene 8	0.044
Ar	androgen receptor	0.042
Dao	D-amino acid oxidase	0.041
Sult4a1	sulfotransferase family 4A, member 1	0.040
Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	0.040
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.040
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.040
Smyd1	SET and MYND domain containing 1	0.039
Cplx1	complexin 1	0.039
Drd3	dopamine receptor D3	0.039	Mouse
Rph3a	rabphilin 3A	0.038
Mapt	microtubule-associated protein tau	0.037
Timp4	tissue inhibitor of metalloproteinase 4	0.037
Nat8	N-acetyltransferase 8 (GCN5-related, putative)	0.037	Mouse
Pdzd3	PDZ domain containing 3	0.036
Epb4.9	erythrocyte protein band 4.9	0.036
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.035	Mouse
Cnr1	cannabinoid receptor 1 (brain)	0.035
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.034
Lhx3	LIM homeobox protein 3	0.034
Slc18a1	solute carrier family 18 (vesicular monoamine), member 1	0.034	Rat
Snap25	synaptosomal-associated protein 25	0.033
Inadl	InaD-like (Drosophila)	0.033
Scn10a	sodium channel, voltage-gated, type X, alpha	0.032
Nt5e	5' nucleotidase, ecto	0.032
Kl	klotho	0.031
Pick1	protein interacting with C kinase 1	0.031
Glra1	glycine receptor, alpha 1 subunit	0.031
Wt1	Wilms tumor 1 homolog	0.031
Plcb1	phospholipase C, beta 1	0.031
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.030	Mouse
Keg1	kidney expressed gene 1	0.030
Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.030
Csnk1e	casein kinase 1, epsilon	0.029
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.029
Cntn2	contactin 2	0.029
Unc79	unc-79 homolog (C. elegans)	0.029
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.028
Th	tyrosine hydroxylase	0.028
Col4a3	collagen, type IV, alpha 3	0.027
En1	engrailed 1	0.027
Btrc	beta-transducin repeat containing protein	0.027
Npy1r	neuropeptide Y receptor Y1	0.027
Adora2a	adenosine A2a receptor	0.026
Slc5a1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.026
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.026
Gal	galanin	0.026
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.026	Mouse
Calb1	calbindin 1	0.026
Neurod2	neurogenic differentiation 2	0.026
Gfap	glial fibrillary acidic protein	0.025
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.025	Mouse
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.025
C1ql1	complement component 1, q subcomponent-like 1	0.025
Acot3	acyl-CoA thioesterase 3	0.025
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.025
Efhd1	EF hand domain containing 1	0.024
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.024
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.024
Mbp	myelin basic protein	0.023
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.023
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.023
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.023
Hsd3b4	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4	0.023
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.022
Aadat	aminoadipate aminotransferase	0.022
Fgf9	fibroblast growth factor 9	0.022
Gpm6b	glycoprotein m6b	0.021
Avpr2	arginine vasopressin receptor 2	0.021
Lep	leptin	0.021
Emx1	empty spiracles homolog 1 (Drosophila)	0.021
Tmem116	transmembrane protein 116	0.021
Clcnka	chloride channel Ka	0.020
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.020
Fmo2	flavin containing monooxygenase 2	0.020
G6pc	glucose-6-phosphatase, catalytic	0.020
Crx	cone-rod homeobox containing gene	0.020
Dab1	disabled homolog 1 (Drosophila)	0.020
Trh	thyrotropin releasing hormone	0.020
Clstn1	calsyntenin 1	0.019
Irs2	insulin receptor substrate 2	0.019
Slco1a6	solute carrier organic anion transporter family, member 1a6	0.019
Cnnm1	cyclin M1	0.019
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.019
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.019
Acot4	acyl-CoA thioesterase 4	0.019
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.019
Akr1c21	aldo-keto reductase family 1, member C21	0.019
Scnn1g	sodium channel, nonvoltage-gated 1 gamma	0.019
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.018
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.018
Cav1	caveolin 1, caveolae protein	0.018
Cbln3	cerebellin 3 precursor protein	0.018
Nrip3	nuclear receptor interacting protein 3	0.018
Sparcl1	SPARC-like 1	0.018
Neurog3	neurogenin 3	0.018
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.018
Defb11	defensin beta 11	0.018
Hbb-b2	hemoglobin, beta adult minor chain	0.018
Gng3	guanine nucleotide binding protein (G protein), gamma 3	0.018
Mybpc3	myosin binding protein C, cardiac	0.018
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.018	Mouse
Col4a4	collagen, type IV, alpha 4	0.018
Slc12a5	solute carrier family 12, member 5	0.018
Vamp2	vesicle-associated membrane protein 2	0.017
Plau	plasminogen activator, urokinase	0.017
Phkg1	phosphorylase kinase gamma 1	0.017
Crhr2	corticotropin releasing hormone receptor 2	0.017
St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.017
Kcna7	potassium voltage-gated channel, shaker-related subfamily, member 7	0.016
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.016	Mouse
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.016
Insr	insulin receptor	0.016
Crhr1	corticotropin releasing hormone receptor 1	0.016
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.016
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.016
Tuba1a	tubulin, alpha 1A	0.016
Vegfa	vascular endothelial growth factor A	0.016
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.016
Grid2	glutamate receptor, ionotropic, delta 2	0.016
Ina	internexin neuronal intermediate filament protein, alpha	0.016	Mouse
Htr5b	5-hydroxytryptamine (serotonin) receptor 5B	0.016
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.015
Lrp2	low density lipoprotein receptor-related protein 2	0.015
Pdzk1	PDZ domain containing 1	0.015
Dnase1	deoxyribonuclease I	0.015
Mapk10	mitogen-activated protein kinase 10	0.015
Sncb	synuclein, beta	0.015
Gja3	gap junction protein, alpha 3	0.015
Frmd5	FERM domain containing 5	0.015
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.015
Cml2	camello-like 2	0.015	Mouse
Srrm3	serine/arginine repetitive matrix 3	0.015
Stmn2	stathmin-like 2	0.015
Fgf1	fibroblast growth factor 1	0.015
Prph	peripherin	0.015	Mouse
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.015
Slc4a5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	0.015
Plat	plasminogen activator, tissue	0.015
Paqr7	progestin and adipoQ receptor family member VII	0.015
Epas1	endothelial PAS domain protein 1	0.015
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.014
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.014
Atp6v0a4	ATPase, H+ transporting, lysosomal V0 subunit A4	0.014
Adcyap1	adenylate cyclase activating polypeptide 1	0.014
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.014
Gcgr	glucagon receptor	0.014
Gpr37l1	G protein-coupled receptor 37-like 1	0.014
Mobp	myelin-associated oligodendrocytic basic protein	0.014
Krt86	keratin 86	0.014
Slc22a4	solute carrier family 22 (organic cation transporter), member 4	0.014
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.014
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.014
Prkce	protein kinase C, epsilon	0.014
Slc13a3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.014
Slc6a18	solute carrier family 6 (neurotransmitter transporter), member 18	0.014	Mouse
Mmp17	matrix metallopeptidase 17	0.013
Fgf13	fibroblast growth factor 13	0.013
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.013
Slc22a13	solute carrier family 22 (organic cation transporter), member 13	0.013
Ptprn	protein tyrosine phosphatase, receptor type, N	0.013
Bdnf	brain derived neurotrophic factor	0.013
Adra2b	adrenergic receptor, alpha 2b	0.013
Nptx1	neuronal pentraxin 1	0.013
Prr15	proline rich 15	0.013
Cckbr	cholecystokinin B receptor	0.013
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.013
Srrm4	serine/arginine repetitive matrix 4	0.013
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.013
Slc17a3	solute carrier family 17 (sodium phosphate), member 3	0.013
Ntsr2	neurotensin receptor 2	0.013
Gabrr2	gamma-aminobutyric acid (GABA) C receptor, subunit rho 2	0.013
BC027072	cDNA sequence BC027072	0.013
Tmem144	transmembrane protein 144	0.013
Prox1	prospero-related homeobox 1	0.013
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.013
Kcnk3	potassium channel, subfamily K, member 3	0.013
Gad1	glutamic acid decarboxylase 1	0.013
Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.013
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.013
Oprk1	opioid receptor, kappa 1	0.013
Slc7a12	solute carrier family 7 (cationic amino acid transporter, y+ system), member 12	0.012
Actn2	actinin alpha 2	0.012
Mrvi1	MRV integration site 1	0.012
Dhh	desert hedgehog	0.012
Wnt3	wingless-related MMTV integration site 3	0.012
Alk	anaplastic lymphoma kinase	0.012
Dusp15	dual specificity phosphatase-like 15	0.012
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.012
Plin4	perilipin 4	0.012
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.012
Ndrg4	N-myc downstream regulated gene 4	0.012
Oprm1	opioid receptor, mu 1	0.012
Gast	gastrin	0.012
Syp	synaptophysin	0.012
Fxyd7	FXYD domain-containing ion transport regulator 7	0.012
Srcin1	SRC kinase signaling inhibitor 1	0.012
Tph2	tryptophan hydroxylase 2	0.012
Shank3	SH3/ankyrin domain gene 3	0.012
Folr1	folate receptor 1 (adult)	0.012
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.012
Hspb2	heat shock protein 2	0.012
D17H6S56E-3	DNA segment, Chr 17, human D6S56E 3	0.012
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.011
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.011
Syn2	synapsin II	0.011
Slc19a3	solute carrier family 19 (sodium/hydrogen exchanger), member 3	0.011
Vil1	villin 1	0.011
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.011
Cml5	camello-like 5	0.011	Mouse
Celf4	CUGBP, Elav-like family member 4	0.011
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.011
Aqp4	aquaporin 4	0.011
Il6	interleukin 6	0.011
Esrrg	estrogen-related receptor gamma	0.011
Glyctk	glycerate kinase	0.011
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.011
Dmgdh	dimethylglycine dehydrogenase precursor	0.011
Slc2a5	solute carrier family 2 (facilitated glucose transporter), member 5	0.011
Spp2	secreted phosphoprotein 2	0.011
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.011
Mogat2	monoacylglycerol O-acyltransferase 2	0.011
Bsnd	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.011
Mip	major intrinsic protein of eye lens fiber	0.011
Ndp	Norrie disease (pseudoglioma) (human)	0.011
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.011
Prkg1	protein kinase, cGMP-dependent, type I	0.011
Clgn	calmegin	0.011
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.011
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.011
Slc29a2	solute carrier family 29 (nucleoside transporters), member 2	0.011
Pvalb	parvalbumin	0.011
Cmtm5	CKLF-like MARVEL transmembrane domain containing 5	0.011
Calb2	calbindin 2	0.011
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.011
Gjb6	gap junction protein, beta 6	0.011
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.011
Arl4d	ADP-ribosylation factor-like 4D	0.011
Ldlr	low density lipoprotein receptor	0.011
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.011
Hint1	histidine triad nucleotide binding protein 1	0.010
Hao2	hydroxyacid oxidase 2	0.010
Mab21l2	mab-21-like 2 (C. elegans)	0.010
Hspa1l	heat shock protein 1-like	0.010
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.010
Pygm	muscle glycogen phosphorylase	0.010
Agtr1a	angiotensin II receptor, type 1a	0.010
Cubn	cubilin (intrinsic factor-cobalamin receptor)	0.010
Apln	apelin	0.010
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.010
Mfsd4	major facilitator superfamily domain containing 4	0.010
Mog	myelin oligodendrocyte glycoprotein	0.010
Agtr2	angiotensin II receptor, type 2	0.010
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.010