Mus musculus

142 known processes

Nkx3-2

NK3 homeobox 2

(Aliases: Bapx1,NKX3.2,Nkx-3.2)

Nkx3-2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.940
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.929
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.923
pancreatic pp cell differentiation GO:0003312 2 0.923
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.914
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.911
embryonic heart tube formation GO:0003144 1 0.907
pancreatic pp cell fate commitment GO:0003329 2 0.874
Mouse
astrocyte fate commitment GO:0060018 4 0.835
auditory receptor cell fate determination GO:0042668 3 0.834
hemangioblast cell differentiation GO:0060217 1 0.828
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.825
Mouse
metanephric capsule specification GO:0072267 1 0.818
skeletal system development GO:0001501 356 0.777
positive regulation of transcription via serum response element binding GO:0010735 1 0.776
Mouse
muscle system process GO:0003012 141 0.765
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.745
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.717
positive regulation of glial cell differentiation GO:0045687 21 0.716
Mouse
negative regulation of cell development GO:0010721 169 0.711
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.690
ventral spinal cord interneuron fate commitment GO:0060579 14 0.689
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.687
auditory receptor cell fate specification GO:0042667 1 0.682
ventral spinal cord interneuron fate determination GO:0060580 1 0.680
Mouse
cartilage development GO:0051216 140 0.674
purkinje myocyte differentiation GO:0003168 1 0.672
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.659
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.659
forebrain regionalization GO:0021871 25 0.640
Mouse
positive regulation of transcription by glucose GO:0046016 3 0.629
atrioventricular node cell development GO:0060928 2 0.621
Mouse
cardiac chamber development GO:0003205 108 0.619
Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.616
endodermal cell fate specification GO:0001714 4 0.615
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.609
his purkinje system cell differentiation GO:0060932 2 0.608
Mouse
ventral spinal cord development GO:0021517 48 0.604
Mouse
subpallium neuron fate commitment GO:0060163 2 0.602
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.587
Mouse
regulation of mast cell differentiation GO:0060375 3 0.565
pancreatic a cell fate commitment GO:0003326 2 0.564
Mouse
neuron migration GO:0001764 122 0.563
Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.562
proepicardium development GO:0003342 2 0.556
Mouse
his purkinje system development GO:0003164 4 0.555
Mouse
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.550
chondrocyte differentiation GO:0002062 72 0.546
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.532
skeletal system morphogenesis GO:0048705 203 0.516
embryonic placenta development GO:0001892 98 0.514
globus pallidus development GO:0021759 2 0.511
Mouse
ventricular cardiac myofibril assembly GO:0055005 3 0.511
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.487
muscle contraction GO:0006936 101 0.486
Mouse
cardiac pacemaker cell fate commitment GO:0060927 1 0.482
Mouse
pyramidal neuron migration GO:0021852 1 0.482
spinal cord patterning GO:0021511 25 0.466
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.452
spinal cord development GO:0021510 81 0.449
Mouse
middle ear morphogenesis GO:0042474 23 0.445
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.441
Mouse
cardiac ventricle development GO:0003231 83 0.440
Mouse
negative regulation of gastrulation GO:2000542 3 0.438
regionalization GO:0003002 337 0.437
Mouse
atrioventricular node cell fate commitment GO:0060929 1 0.432
Mouse
digestive tract morphogenesis GO:0048546 147 0.430
Mouse
deltoid tuberosity development GO:0035993 3 0.424
regulation of adaptive immune response GO:0002819 90 0.422
atrial cardiac muscle cell development GO:0055014 2 0.420
Mouse
atrioventricular node cell differentiation GO:0060922 2 0.419
Mouse
cardiac septum development GO:0003279 59 0.418
hindbrain development GO:0030902 128 0.413
renal capsule specification GO:0072130 1 0.410
response to growth factor GO:0070848 198 0.409
atrial cardiac muscle cell differentiation GO:0055011 2 0.407
Mouse
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.399
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.395
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.394
regulation of gliogenesis GO:0014013 50 0.383
Mouse
ear morphogenesis GO:0042471 118 0.380
metanephric capsule formation GO:0072266 1 0.377
forebrain neuron fate commitment GO:0021877 13 0.374
Mouse
t cell differentiation GO:0030217 174 0.362
Mouse
negative regulation of cell fate specification GO:0009996 4 0.360
cell differentiation involved in embryonic placenta development GO:0060706 26 0.357
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.356
cell proliferation in hindbrain GO:0021534 10 0.350
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.349
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.348
cardiac septum morphogenesis GO:0060411 46 0.346
apoptotic process involved in heart morphogenesis GO:0003278 5 0.345
Mouse
endochondral bone morphogenesis GO:0060350 50 0.339
cell fate commitment GO:0045165 210 0.338
Mouse
nitrogen compound transport GO:0071705 271 0.337
embryonic digit morphogenesis GO:0042733 56 0.336
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.335
bone development GO:0060348 120 0.332
regulation of cell cycle GO:0051726 281 0.323
regulation of cardiac muscle cell apoptotic process GO:0010665 9 0.320
Mouse
ectoderm formation GO:0001705 3 0.320
menarche GO:0042696 1 0.316
Mouse
inflammatory response GO:0006954 244 0.307
circulatory system process GO:0003013 197 0.305
Mouse
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.300
connective tissue development GO:0061448 179 0.296
cardiac right ventricle formation GO:0003219 3 0.296
embryonic skeletal system development GO:0048706 120 0.294
cellular amino acid metabolic process GO:0006520 103 0.291
extracellular matrix organization GO:0030198 147 0.286
chondrocyte development GO:0002063 24 0.286
positive regulation of exit from mitosis GO:0031536 1 0.285
sensory perception of mechanical stimulus GO:0050954 107 0.283
regulation of endodermal cell fate specification GO:0042663 2 0.282
prostate gland stromal morphogenesis GO:0060741 2 0.282
ventricular cardiac muscle tissue development GO:0003229 38 0.280
Mouse
regulation of organ morphogenesis GO:2000027 144 0.277
specification of organ position GO:0010159 3 0.275
trachea cartilage morphogenesis GO:0060535 4 0.272
regulation of cellular component biogenesis GO:0044087 181 0.272
Mouse
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.269
appendage development GO:0048736 166 0.267
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.257
cardiac muscle tissue morphogenesis GO:0055008 44 0.256
Mouse
regulation of cartilage development GO:0061035 44 0.255
lung cell differentiation GO:0060479 30 0.254
Mouse
carbon catabolite regulation of transcription GO:0045990 4 0.249
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.247
Mouse
mesoderm development GO:0007498 100 0.246
Fly
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.245
ventral spinal cord interneuron specification GO:0021521 11 0.245
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.245
transdifferentiation GO:0060290 1 0.244
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.243
negative regulation of organelle organization GO:0010639 90 0.242
plasma cell differentiation GO:0002317 3 0.241
Mouse
lung development GO:0030324 164 0.238
Mouse
regulation of neuron differentiation GO:0045664 281 0.228
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.227
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.225
regulation of auditory receptor cell differentiation GO:0045607 4 0.223
vascular wound healing GO:0061042 3 0.222
spinal cord dorsal ventral patterning GO:0021513 23 0.220
Mouse
smoothened signaling pathway GO:0007224 105 0.220
Mouse
sensory perception of sound GO:0007605 97 0.219
blood vessel remodeling GO:0001974 33 0.219
positive regulation of synaptic plasticity GO:0031915 4 0.214
regulation of response to wounding GO:1903034 189 0.213
positive regulation of cell development GO:0010720 237 0.210
Mouse
intestinal epithelial structure maintenance GO:0060729 4 0.210
positive regulation of keratinocyte proliferation GO:0010838 4 0.208
chromatin modification GO:0016568 187 0.207
negative regulation of neuron differentiation GO:0045665 101 0.206
Mouse
tendon formation GO:0035992 4 0.206
multicellular organismal metabolic process GO:0044236 28 0.204
glucose homeostasis GO:0042593 128 0.204
sensory perception GO:0007600 245 0.202
mesonephric tubule development GO:0072164 94 0.201
regulation of lymphocyte mediated immunity GO:0002706 84 0.201
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.200
neural tube closure GO:0001843 90 0.199
negative regulation of synapse maturation GO:2000297 2 0.198
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.197
Mouse
renal capsule morphogenesis GO:0072128 1 0.196
embryonic organ morphogenesis GO:0048562 276 0.196
regulation of organelle organization GO:0033043 289 0.196
cerebral cortex development GO:0021987 86 0.196
Mouse
metencephalon development GO:0022037 89 0.196
muscle tissue morphogenesis GO:0060415 53 0.195
Mouse
limbic system development GO:0021761 72 0.193
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.191
positive regulation of nervous system development GO:0051962 221 0.191
Mouse
autonomic nervous system development GO:0048483 43 0.191
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.189
hematopoietic progenitor cell differentiation GO:0002244 143 0.188
embryonic viscerocranium morphogenesis GO:0048703 8 0.187
cell fate specification involved in pattern specification GO:0060573 11 0.187
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.186
regulation of vascular wound healing GO:0061043 2 0.184
sensory organ morphogenesis GO:0090596 242 0.184
forebrain development GO:0030900 302 0.183
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.182
visceral serous pericardium development GO:0061032 2 0.181
endocrine system development GO:0035270 98 0.180
Mouse
cell fate commitment involved in pattern specification GO:0060581 14 0.177
Mouse
regulation of gastrulation GO:0010470 16 0.177
cartilage condensation GO:0001502 18 0.175
carbon catabolite activation of transcription GO:0045991 4 0.173
negative regulation of immune system process GO:0002683 209 0.172
bone morphogenesis GO:0060349 78 0.172
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.171
leukocyte activation involved in immune response GO:0002366 126 0.170
Mouse
positive regulation of cell death GO:0010942 224 0.170
embryonic heart tube morphogenesis GO:0003143 51 0.168
Mouse
extracellular structure organization GO:0043062 148 0.168
lateral line system development GO:0048925 1 0.167
cardiac chamber formation GO:0003207 10 0.167
Mouse
mammary gland morphogenesis GO:0060443 54 0.167
cellular response to cytokine stimulus GO:0071345 189 0.165
leydig cell differentiation GO:0033327 10 0.163
Mouse
spinal cord motor neuron differentiation GO:0021522 35 0.162
Mouse
epithelial tube morphogenesis GO:0060562 303 0.162
Mouse
gliogenesis GO:0042063 141 0.161
Mouse
regulation of system process GO:0044057 200 0.161
Mouse
respiratory tube development GO:0030323 167 0.161
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.161
t cell activation GO:0042110 289 0.161
Mouse
positive regulation of vascular wound healing GO:0035470 1 0.160
hypophysis morphogenesis GO:0048850 3 0.160
developmental maturation GO:0021700 193 0.160
telencephalon regionalization GO:0021978 14 0.160
ameboidal type cell migration GO:0001667 128 0.159
respiratory system development GO:0060541 190 0.157
Mouse
sclerotome development GO:0061056 4 0.157
somatic sex determination GO:0018993 2 0.156
renal capsule formation GO:0072129 1 0.156
determination of heart left right asymmetry GO:0061371 48 0.155
Mouse
glial cell fate commitment GO:0021781 14 0.154
Mouse
cardiac muscle tissue development GO:0048738 130 0.153
Mouse
bundle of his development GO:0003166 4 0.153
Mouse
cell fate specification GO:0001708 72 0.152
Mouse
pattern specification involved in metanephros development GO:0072268 4 0.152
regulation of wnt signaling pathway GO:0030111 123 0.151
Mouse
striated muscle tissue development GO:0014706 293 0.149
Mouse
embryonic limb morphogenesis GO:0030326 126 0.149
detection of glucose GO:0051594 1 0.148
regulation of cellular response to stress GO:0080135 159 0.148
regulation of cardioblast differentiation GO:0051890 3 0.145
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.145
regulation of neuron projection development GO:0010975 169 0.145
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.145
ventricular septum development GO:0003281 42 0.144
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.144
ear development GO:0043583 200 0.143
biomineral tissue development GO:0031214 64 0.143
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.141
cell type specific apoptotic process GO:0097285 268 0.140
Mouse
digestive tract development GO:0048565 190 0.140
cell differentiation in spinal cord GO:0021515 53 0.139
Mouse
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.138
Mouse
trophoblast giant cell differentiation GO:0060707 15 0.137
cell proliferation involved in heart valve development GO:2000793 2 0.137
central nervous system neuron differentiation GO:0021953 162 0.137
Mouse
ventral spinal cord interneuron differentiation GO:0021514 16 0.136
Mouse
mitral valve morphogenesis GO:0003183 4 0.136
chromatin organization GO:0006325 206 0.135
camera type eye development GO:0043010 266 0.134
wnt signaling pathway GO:0016055 188 0.133
Mouse
metanephric capsule morphogenesis GO:0072265 1 0.133
regulation of endodermal cell differentiation GO:1903224 2 0.133
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.131
negative regulation of cellular component organization GO:0051129 194 0.131
single fertilization GO:0007338 82 0.130
neuron fate specification GO:0048665 30 0.129
Mouse
embryonic heart tube left right pattern formation GO:0060971 5 0.128
Mouse
placenta development GO:0001890 140 0.128
pallium development GO:0021543 120 0.128
Mouse
endomembrane system organization GO:0010256 147 0.128
limb development GO:0060173 166 0.128
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.128
ventricular septum morphogenesis GO:0060412 27 0.128
oligodendrocyte differentiation GO:0048709 53 0.127
Mouse
cellular ketone metabolic process GO:0042180 84 0.127
heart trabecula formation GO:0060347 14 0.126
Mouse
sinoatrial node cell differentiation GO:0060921 3 0.126
branching involved in ureteric bud morphogenesis GO:0001658 56 0.126
organic hydroxy compound metabolic process GO:1901615 203 0.125
female somatic sex determination GO:0019101 1 0.124
regulation of blood circulation GO:1903522 93 0.122
Mouse
rhythmic process GO:0048511 174 0.121
Mouse
endodermal cell fate commitment GO:0001711 12 0.121
skeletal muscle cell differentiation GO:0035914 66 0.121
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.121
forebrain neuron differentiation GO:0021879 52 0.120
Mouse
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.120
negative regulation of chondrocyte differentiation GO:0032331 13 0.120
glomerular mesangial cell development GO:0072144 3 0.120
mesangial cell differentiation GO:0072007 4 0.120
calcium ion transport GO:0006816 159 0.120
Mouse
leukocyte differentiation GO:0002521 342 0.119
Mouse
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.119
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.118
Mouse
glandular epithelial cell differentiation GO:0002067 38 0.117
Mouse
cerebellum development GO:0021549 77 0.117
regulation of synaptic plasticity GO:0048167 87 0.117
diencephalon development GO:0021536 63 0.117
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.116
multicellular organismal response to stress GO:0033555 62 0.115
cardiac conduction system development GO:0003161 12 0.114
Mouse
alpha beta t cell differentiation GO:0046632 69 0.114
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.114
noradrenergic neuron development GO:0003358 3 0.113
cardiocyte differentiation GO:0035051 87 0.113
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.112
Mouse
stem cell proliferation GO:0072089 117 0.112
negative regulation of nervous system development GO:0051961 156 0.112
Mouse
cell adhesion GO:0007155 329 0.112
epithelial tube formation GO:0072175 130 0.111
cell fate determination involved in pattern specification GO:0060582 1 0.111
Mouse
cell activation involved in immune response GO:0002263 126 0.110
Mouse
muscle tissue development GO:0060537 308 0.110
Mouse
multicellular organismal homeostasis GO:0048871 164 0.109
negative regulation of transcription by glucose GO:0045014 1 0.109
collagen metabolic process GO:0032963 17 0.109
midbrain hindbrain boundary maturation GO:0021732 1 0.109
positive regulation of response to wounding GO:1903036 66 0.109
mitral valve development GO:0003174 4 0.109
regulation of stem cell proliferation GO:0072091 78 0.108
ossification GO:0001503 216 0.108
blood circulation GO:0008015 195 0.107
Mouse
endocardial cushion formation GO:0003272 13 0.107
regulation of smoothened signaling pathway GO:0008589 58 0.107
hypothalamus development GO:0021854 16 0.107
Mouse
lung epithelial cell differentiation GO:0060487 29 0.107
Mouse
negative regulation of neuron projection development GO:0010977 50 0.107
bmp signaling pathway GO:0030509 93 0.106
Mouse
granulosa cell differentiation GO:0060014 1 0.106
apoptotic signaling pathway GO:0097190 306 0.106
immune effector process GO:0002252 321 0.105
Mouse
tissue remodeling GO:0048771 102 0.105
cell proliferation in external granule layer GO:0021924 10 0.105
olfactory lobe development GO:0021988 32 0.104
epithelial cell proliferation GO:0050673 174 0.104
Mouse
osteoblast development GO:0002076 17 0.103
heart contraction GO:0060047 93 0.103
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.103
stem cell differentiation GO:0048863 268 0.103
Mouse
telencephalon cell migration GO:0022029 55 0.103
Mouse
tongue development GO:0043586 18 0.103
Mouse
negative regulation of glucokinase activity GO:0033132 4 0.103
cardiac ventricle formation GO:0003211 8 0.102
Mouse
mesoderm morphogenesis GO:0048332 64 0.102
lung epithelium development GO:0060428 37 0.101
Mouse
lymphocyte differentiation GO:0030098 242 0.100
Mouse
artery development GO:0060840 53 0.100
positive regulation of cardioblast differentiation GO:0051891 3 0.099
Mouse
cation homeostasis GO:0055080 212 0.098
collagen biosynthetic process GO:0032964 7 0.098
columnar cuboidal epithelial cell development GO:0002066 29 0.097
cytokine production GO:0001816 319 0.097
endoderm development GO:0007492 45 0.097
Mouse
negative regulation of endodermal cell differentiation GO:1903225 1 0.097
heart valve morphogenesis GO:0003179 21 0.097
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.096
angiogenesis GO:0001525 201 0.096
forebrain cell migration GO:0021885 58 0.094
Mouse
appendage morphogenesis GO:0035107 149 0.094
skin morphogenesis GO:0043589 38 0.093
regulation of protein complex assembly GO:0043254 83 0.093
Mouse
skeletal muscle organ development GO:0060538 163 0.093
positive regulation of sodium ion transport GO:0010765 13 0.093
Mouse
mesonephric epithelium development GO:0072163 94 0.092
primary prostatic bud elongation GO:0060516 2 0.092
embryonic eye morphogenesis GO:0048048 29 0.092
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.091
specification of organ identity GO:0010092 30 0.091
metanephric nephron tubule formation GO:0072289 4 0.090
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.090
stem cell maintenance GO:0019827 130 0.090
neural tube patterning GO:0021532 43 0.090
positive regulation of cartilage development GO:0061036 18 0.090
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.089
endocrine pancreas development GO:0031018 29 0.089
Mouse
regulation of immunoglobulin production GO:0002637 42 0.088
regulation of detection of glucose GO:2000970 1 0.088
renal vesicle induction GO:0072034 3 0.088
regulation of cytokine production GO:0001817 266 0.088
locus ceruleus development GO:0021703 1 0.087
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.087
detection of monosaccharide stimulus GO:0034287 1 0.087
olfactory bulb development GO:0021772 30 0.087
oligodendrocyte development GO:0014003 20 0.086
Mouse
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.086
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.086
dorsal spinal cord development GO:0021516 20 0.085
regulation of histone modification GO:0031056 56 0.085
molting cycle GO:0042303 90 0.084
positive regulation of cell migration GO:0030335 109 0.084
intracellular distribution of mitochondria GO:0048312 1 0.084
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.084
regulation of mitotic cell cycle GO:0007346 126 0.084
regulation of cell motility GO:2000145 236 0.083
renal capsule development GO:0072127 1 0.083
synaptic transmission GO:0007268 329 0.083
face morphogenesis GO:0060325 29 0.083
cerebellar granule cell precursor proliferation GO:0021930 10 0.083
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.082
pancreatic a cell differentiation GO:0003310 7 0.082
Mouse
segmentation GO:0035282 93 0.082
embryonic epithelial tube formation GO:0001838 130 0.082
regulation of multi organism process GO:0043900 111 0.081
regulation of tumor necrosis factor production GO:0032680 49 0.081
glomerular mesangial cell differentiation GO:0072008 3 0.080
glial cell differentiation GO:0010001 131 0.080
Mouse
b cell activation involved in immune response GO:0002312 50 0.080
Mouse
outflow tract morphogenesis GO:0003151 53 0.080
Mouse
cellular homeostasis GO:0019725 240 0.079
amine metabolic process GO:0009308 45 0.079
positive regulation of cytokine production GO:0001819 174 0.078
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.078
Mouse
trachea formation GO:0060440 3 0.078
positive regulation of gliogenesis GO:0014015 27 0.078
Mouse
trophectodermal cell differentiation GO:0001829 21 0.077
regulation of secretion GO:0051046 274 0.077
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.077
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.077
somitogenesis GO:0001756 69 0.077
atrial ventricular junction remodeling GO:0003294 2 0.077
sensory perception of pain GO:0019233 47 0.076
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.075
Mouse
mesodermal cell migration GO:0008078 4 0.075
renal tubule morphogenesis GO:0061333 72 0.075
endocardial cushion to mesenchymal transition GO:0090500 5 0.074
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.074
regulation of cell adhesion GO:0030155 154 0.074
positive regulation of neuroblast proliferation GO:0002052 19 0.074
hippocampus development GO:0021766 52 0.074
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.074
Mouse
forebrain dorsal ventral pattern formation GO:0021798 6 0.073
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.073
carbon catabolite repression of transcription GO:0045013 1 0.073
cellular response to inorganic substance GO:0071241 37 0.073
blood vessel morphogenesis GO:0048514 285 0.073
Mouse
dorsal ventral neural tube patterning GO:0021904 28 0.073
regulation of homeostatic process GO:0032844 182 0.072
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.072
amacrine cell differentiation GO:0035881 5 0.072
negative regulation of epithelial cell proliferation GO:0050680 64 0.072
Mouse
cell maturation GO:0048469 127 0.072
heart valve development GO:0003170 23 0.072
protein acylation GO:0043543 64 0.071
acute inflammatory response GO:0002526 41 0.071
g protein coupled receptor signaling pathway GO:0007186 243 0.071
embryonic camera type eye development GO:0031076 36 0.071
cellular lipid metabolic process GO:0044255 323 0.071
Mouse
b cell mediated immunity GO:0019724 71 0.071
nephron morphogenesis GO:0072028 69 0.071
positive regulation of phospholipase activity GO:0010518 3 0.071
visceral motor neuron differentiation GO:0021524 3 0.069
positive regulation of cell cycle GO:0045787 92 0.069
multicellular organismal macromolecule metabolic process GO:0044259 19 0.069
cellular amine metabolic process GO:0044106 44 0.069
digestive system development GO:0055123 200 0.068
mitochondrion organization GO:0007005 134 0.068
protein catabolic process GO:0030163 221 0.067
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.067
developmental induction GO:0031128 34 0.067
Mouse
epithelial cell morphogenesis GO:0003382 41 0.067
developmental growth involved in morphogenesis GO:0060560 138 0.067
transcription from rna polymerase iii promoter GO:0006383 3 0.067
cardiac pacemaker cell development GO:0060926 5 0.066
Mouse
aortic valve morphogenesis GO:0003180 4 0.066
striated muscle cell development GO:0055002 125 0.066
Mouse
organ growth GO:0035265 117 0.066
Mouse
ovulation cycle GO:0042698 59 0.065
somatic diversification of immune receptors GO:0002200 53 0.065
regulation of transcription by glucose GO:0046015 3 0.065
keratinocyte proliferation GO:0043616 21 0.064
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.064
regulation of reproductive process GO:2000241 66 0.063
somite rostral caudal axis specification GO:0032525 13 0.063
positive regulation of leukocyte mediated immunity GO:0002705 70 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.063
leukocyte mediated immunity GO:0002443 174 0.062
striated muscle cell apoptotic process GO:0010658 12 0.062
Mouse
lipoprotein biosynthetic process GO:0042158 33 0.062
cerebral cortex neuron differentiation GO:0021895 19 0.062
Mouse
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.062
positive regulation of programmed cell death GO:0043068 218 0.062
maintenance of location GO:0051235 89 0.061
glial cell fate specification GO:0021780 5 0.061
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.061
ventricular cardiac muscle cell development GO:0055015 11 0.061
Mouse
positive regulation of dna templated transcription elongation GO:0032786 2 0.061
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.061
tumor necrosis factor production GO:0032640 50 0.061
mitotic cell cycle process GO:1903047 159 0.061
midbrain development GO:0030901 35 0.061
cellular response to amino acid stimulus GO:0071230 29 0.060
neuron fate determination GO:0048664 9 0.059
Mouse
cation transport GO:0006812 399 0.058
Mouse
determination of left right symmetry GO:0007368 80 0.058
embryonic forelimb morphogenesis GO:0035115 32 0.058
renal system process GO:0003014 48 0.058
negative regulation of apoptotic signaling pathway GO:2001234 104 0.058
organonitrogen compound biosynthetic process GO:1901566 192 0.058
regulation of osteoblast differentiation GO:0045667 67 0.058
head morphogenesis GO:0060323 34 0.057
regulation of striated muscle cell apoptotic process GO:0010662 11 0.057
Mouse
cell communication by chemical coupling GO:0010643 2 0.057
mucosal associated lymphoid tissue development GO:0048537 12 0.057
Mouse
neural nucleus development GO:0048857 22 0.056
Mouse
neuron projection guidance GO:0097485 141 0.056
Mouse

Nkx3-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.117
disease of anatomical entity DOID:7 0 0.117
musculoskeletal system disease DOID:17 0 0.117
connective tissue disease DOID:65 0 0.117
nervous system disease DOID:863 0 0.078