IMP

Process View

Mus musculus

8 genes annotated in mouse

cardiac ventricle formation

The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cardiac ventricle formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cardiac ventricle formation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.999
Pitx2	paired-like homeodomain transcription factor 2	0.998
Pax3	paired box gene 3	0.991
Fgf8	fibroblast growth factor 8	0.989
Hand2	heart and neural crest derivatives expressed transcript 2	0.981
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.981
Hoxa1	homeobox A1	0.953
Tbx1	T-box 1	0.952	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.946
Pitx1	paired-like homeodomain transcription factor 1	0.933
Isl1	ISL1 transcription factor, LIM/homeodomain	0.928
Gata4	GATA binding protein 4	0.924
Fgfr2	fibroblast growth factor receptor 2	0.918
Sall4	sal-like 4 (Drosophila)	0.911
Sox2	SRY-box containing gene 2	0.900	Mouse
Foxc2	forkhead box C2	0.855
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.853
Pax2	paired box gene 2	0.807
Foxc1	forkhead box C1	0.773
Jag1	jagged 1	0.769
Pax6	paired box gene 6	0.762
Tcfap2a	transcription factor AP-2, alpha	0.735
Hand1	heart and neural crest derivatives expressed transcript 1	0.720	Human Mouse
Sox9	SRY-box containing gene 9	0.672	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.641
Bmp4	bone morphogenetic protein 4	0.563
Gli3	GLI-Kruppel family member GLI3	0.551
Mesp1	mesoderm posterior 1	0.538	Human
Eya1	eyes absent 1 homolog (Drosophila)	0.511
Foxg1	forkhead box G1	0.503
Notch1	Notch gene homolog 1 (Drosophila)	0.474
Meox2	mesenchyme homeobox 2	0.470
Vegfa	vascular endothelial growth factor A	0.465
Gsc	goosecoid homeobox	0.450
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.446
Alx4	aristaless-like homeobox 4	0.439
Vangl2	vang-like 2 (van gogh, Drosophila)	0.422
Fgf10	fibroblast growth factor 10	0.404
Tbx3	T-box 3	0.390	Mouse
Gbx2	gastrulation brain homeobox 2	0.356
Tgfb2	transforming growth factor, beta 2	0.338
Prrx1	paired related homeobox 1	0.296
Ptf1a	pancreas specific transcription factor, 1a	0.291	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.284
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.262
Pou5f1	POU domain, class 5, transcription factor 1	0.242
Ntf3	neurotrophin 3	0.241
Tlx3	T-cell leukemia, homeobox 3	0.237
Rarg	retinoic acid receptor, gamma	0.211
Insm1	insulinoma-associated 1	0.209
Msx1	homeobox, msh-like 1	0.205
Hoxa13	homeobox A13	0.185
Nodal	nodal	0.179
Rxra	retinoid X receptor alpha	0.175
Gata6	GATA binding protein 6	0.175
Foxh1	forkhead box H1	0.173
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.157
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.155
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.142
Nos3	nitric oxide synthase 3, endothelial cell	0.140
Wt1	Wilms tumor 1 homolog	0.137
Lmx1b	LIM homeobox transcription factor 1 beta	0.135
Lhx9	LIM homeobox protein 9	0.127
Hoxa3	homeobox A3	0.127
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.123
Emx1	empty spiracles homolog 1 (Drosophila)	0.109
Efnb2	ephrin B2	0.108
Lhx1	LIM homeobox protein 1	0.107
Nkx3-2	NK3 homeobox 2	0.102	Mouse
Sall3	sal-like 3 (Drosophila)	0.095
Ednra	endothelin receptor type A	0.093
Neurog2	neurogenin 2	0.092	Mouse
Tbx5	T-box 5	0.092
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.090
Gli2	GLI-Kruppel family member GLI2	0.089
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.086
Lhx5	LIM homeobox protein 5	0.084
Dll4	delta-like 4 (Drosophila)	0.083
She	src homology 2 domain-containing transforming protein E	0.082
Zeb1	zinc finger E-box binding homeobox 1	0.082
Dlx5	distal-less homeobox 5	0.081
Hoxa2	homeobox A2	0.081
Lmx1a	LIM homeobox transcription factor 1 alpha	0.080
Chrd	chordin	0.079
Rarb	retinoic acid receptor, beta	0.078
Pou4f3	POU domain, class 4, transcription factor 3	0.077
Tcfcp2l1	transcription factor CP2-like 1	0.076
Pax9	paired box gene 9	0.075
Neurod1	neurogenic differentiation 1	0.073	Mouse
Snai1	snail homolog 1 (Drosophila)	0.072
Runx2	runt related transcription factor 2	0.072
Nhlh1	nescient helix loop helix 1	0.072	Mouse
Hoxd13	homeobox D13	0.071
Sox11	SRY-box containing gene 11	0.069
Wnt3a	wingless-related MMTV integration site 3A	0.067
Alx3	aristaless-like homeobox 3	0.066
Myod1	myogenic differentiation 1	0.065
Hoxd3	homeobox D3	0.064
Ebf3	early B-cell factor 3	0.063
En1	engrailed 1	0.060
Pax8	paired box gene 8	0.060
Hoxa4	homeobox A4	0.059
Sox18	SRY-box containing gene 18	0.059	Mouse
Pax1	paired box gene 1	0.057
Sox3	SRY-box containing gene 3	0.057	Mouse
Col22a1	collagen, type XXII, alpha 1	0.056
Atoh7	atonal homolog 7 (Drosophila)	0.055	Mouse
Hoxa11	homeobox A11	0.052
Esrrb	estrogen related receptor, beta	0.052
Smad6	MAD homolog 6 (Drosophila)	0.052
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.051
Fgf3	fibroblast growth factor 3	0.051
Nkx6-1	NK6 homeobox 1	0.051
Pitx3	paired-like homeodomain transcription factor 3	0.049
Hoxd11	homeobox D11	0.048
Gdnf	glial cell line derived neurotrophic factor	0.048
Cdx2	caudal type homeobox 2	0.047
Btbd17	BTB (POZ) domain containing 17	0.046
Hoxd1	homeobox D1	0.046
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.046
Tcf15	transcription factor 15	0.042	Mouse
Hoxb1	homeobox B1	0.041
Neurog3	neurogenin 3	0.040	Mouse
Phox2b	paired-like homeobox 2b	0.040
Lhx3	LIM homeobox protein 3	0.040
T	brachyury	0.040	Mouse
Zic3	zinc finger protein of the cerebellum 3	0.040
Mef2c	myocyte enhancer factor 2C	0.040
Tcf21	transcription factor 21	0.038
Pou4f2	POU domain, class 4, transcription factor 2	0.037
Notch2	Notch gene homolog 2 (Drosophila)	0.037	Mouse
Fgf15	fibroblast growth factor 15	0.037
Prph2	peripherin 2	0.036
Smo	smoothened homolog (Drosophila)	0.036
Arx	aristaless related homeobox	0.036
Gata3	GATA binding protein 3	0.035
Foxf1a	forkhead box F1a	0.035
Fgf4	fibroblast growth factor 4	0.035
Nanog	Nanog homeobox	0.035
Prrx2	paired related homeobox 2	0.034
Hdac7	histone deacetylase 7	0.034
Uncx	UNC homeobox	0.034
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.034
Wnt6	wingless-related MMTV integration site 6	0.033
Gja5	gap junction protein, alpha 5	0.033
Hmx3	H6 homeobox 3	0.032
Arid1a	AT rich interactive domain 1A (SWI-like)	0.032
Pdx1	pancreatic and duodenal homeobox 1	0.032
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.031
Gata1	GATA binding protein 1	0.031
Hes1	hairy and enhancer of split 1 (Drosophila)	0.030
Aplnr	apelin receptor	0.030
Col2a1	collagen, type II, alpha 1	0.030
Sox1	SRY-box containing gene 1	0.029
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.029
Sox7	SRY-box containing gene 7	0.029	Mouse
Nog	noggin	0.029
Tal2	T-cell acute lymphocytic leukemia 2	0.028	Mouse
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.028
Lhx6	LIM homeobox protein 6	0.028
Shox2	short stature homeobox 2	0.027
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.026
Sox4	SRY-box containing gene 4	0.026
Dlx2	distal-less homeobox 2	0.026
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.025
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.025
Rara	retinoic acid receptor, alpha	0.025
Twist2	twist homolog 2 (Drosophila)	0.024	Mouse
Gata2	GATA binding protein 2	0.024
Cldn5	claudin 5	0.024
Sox17	SRY-box containing gene 17	0.024	Mouse
Fgf17	fibroblast growth factor 17	0.024
Robo3	roundabout homolog 3 (Drosophila)	0.024
Ighmbp2	immunoglobulin mu binding protein 2	0.023
Dlx1	distal-less homeobox 1	0.023
Bcl2	B-cell leukemia/lymphoma 2	0.023
Neurod4	neurogenic differentiation 4	0.023	Mouse
Kdr	kinase insert domain protein receptor	0.023
En2	engrailed 2	0.022
Eng	endoglin	0.022
Hoxc6	homeobox C6	0.022
Hdac4	histone deacetylase 4	0.022
Efna2	ephrin A2	0.021
Gdf3	growth differentiation factor 3	0.021
Pou3f3	POU domain, class 3, transcription factor 3	0.021
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.021
Dll1	delta-like 1 (Drosophila)	0.021
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.020
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.020
Hoxc5	homeobox C5	0.020
Hesx1	homeobox gene expressed in ES cells	0.020
Hoxa5	homeobox A5	0.020
Sall1	sal-like 1 (Drosophila)	0.020
Onecut1	one cut domain, family member 1	0.020
Zic1	zinc finger protein of the cerebellum 1	0.020
Hoxa10	homeobox A10	0.019
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.019	Mouse
Gja4	gap junction protein, alpha 4	0.019
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.019	Mouse
Hoxb4	homeobox B4	0.019
Meox1	mesenchyme homeobox 1	0.019
Ret	ret proto-oncogene	0.018
Isl2	insulin related protein 2 (islet 2)	0.018
Mecom	MDS1 and EVI1 complex locus	0.018
Hoxc4	homeobox C4	0.018
Myog	myogenin	0.018
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.018
Adcy4	adenylate cyclase 4	0.018
Pbx1	pre B-cell leukemia transcription factor 1	0.018
Hmx1	H6 homeobox 1	0.017
Scn5a	sodium channel, voltage-gated, type V, alpha	0.017
Cdh5	cadherin 5	0.017
Mnx1	motor neuron and pancreas homeobox 1	0.017
Gata5	GATA binding protein 5	0.017
Egfl7	EGF-like domain 7	0.016
Tgfbr2	transforming growth factor, beta receptor II	0.016
Bdnf	brain derived neurotrophic factor	0.016
Tal1	T-cell acute lymphocytic leukemia 1	0.016	Mouse
Pcdh12	protocadherin 12	0.016
Mmp24	matrix metallopeptidase 24	0.015
Amh	anti-Mullerian hormone	0.015
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.015
Zfpm2	zinc finger protein, multitype 2	0.015
Sim1	single-minded homolog 1 (Drosophila)	0.015
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.014
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.014
Ptprb	protein tyrosine phosphatase, receptor type, B	0.014
Neurog1	neurogenin 1	0.014	Mouse
Lef1	lymphoid enhancer binding factor 1	0.014
Hdac5	histone deacetylase 5	0.013
Acvr1	activin A receptor, type 1	0.013
Foxb1	forkhead box B1	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Foxd2	forkhead box D2	0.013
Tcfap2c	transcription factor AP-2, gamma	0.012
Hoxd12	homeobox D12	0.012
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.012
Myt1	myelin transcription factor 1	0.012
Hoxb3	homeobox B3	0.012
Hoxb13	homeobox B13	0.012
Pou3f4	POU domain, class 3, transcription factor 4	0.012
Ceacam9	carcinoembryonic antigen-related cell adhesion molecule 9	0.012
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.012
Tbx2	T-box 2	0.012	Mouse
Hes5	hairy and enhancer of split 5 (Drosophila)	0.012
Hoxb5	homeobox B5	0.012
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.012
Sim2	single-minded homolog 2 (Drosophila)	0.012
Cer1	cerberus 1 homolog (Xenopus laevis)	0.012
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.011
Gdf11	growth differentiation factor 11	0.011
Emx2	empty spiracles homolog 2 (Drosophila)	0.011
Emid2	EMI domain containing 2	0.011
Hoxd4	homeobox D4	0.011
Bcl6b	B-cell CLL/lymphoma 6, member B	0.011
Fgf18	fibroblast growth factor 18	0.011
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.011
Foxa2	forkhead box A2	0.011
Foxe3	forkhead box E3	0.011
Kcnk3	potassium channel, subfamily K, member 3	0.011
Pou3f2	POU domain, class 3, transcription factor 2	0.011
Tead4	TEA domain family member 4	0.011
Plac1	placental specific protein 1	0.011
Efs	embryonal Fyn-associated substrate	0.010
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.010
Foxb2	forkhead box B2	0.010
Npr3	natriuretic peptide receptor 3	0.010
Esam	endothelial cell-specific adhesion molecule	0.010