|
|
defense response to other organism
|
GO:0098542 |
197 |
0.987
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.970
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.950
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.948
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.946
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.914
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.881
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.879
|
Mouse |
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.870
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.865
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.859
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.851
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.835
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.833
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.832
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.798
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.794
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.789
|
Mouse |
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.787
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.785
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.782
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.775
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.753
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.753
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.748
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.731
|
Mouse |
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.723
|
Mouse |
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.717
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.702
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.700
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.679
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.668
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
9 |
0.656
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.655
|
Human Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.647
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.638
|
Human Mouse |
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.631
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.617
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.611
|
Mouse |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.608
|
Human Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.574
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.571
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.565
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.564
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.553
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.549
|
Mouse |
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.542
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.532
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.531
|
Human Mouse |
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.526
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.516
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.511
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.508
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.506
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.505
|
Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.500
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.488
|
Mouse |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.472
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.470
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.462
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.457
|
Human Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.457
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.446
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.440
|
Mouse |
|
|
necroptotic process
|
GO:0070266 |
21 |
0.435
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.428
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.420
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.414
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.412
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.412
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.410
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.403
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.399
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.394
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.391
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.385
|
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.382
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.381
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.378
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.376
|
Mouse |
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.374
|
Mouse |
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.372
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.367
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.360
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.359
|
Human Mouse |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.356
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.351
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.350
|
Mouse |
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.349
|
Mouse |
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.345
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.341
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.328
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.326
|
Human Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.320
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.318
|
Mouse |
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.316
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.315
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.306
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.304
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.301
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.300
|
Mouse |
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.293
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.287
|
Mouse |
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.286
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.284
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.279
|
Mouse |
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.276
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.272
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.272
|
Mouse |
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.268
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.267
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.265
|
Mouse |
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.256
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.254
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.253
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.252
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.250
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.249
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.248
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.245
|
Mouse |
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.245
|
Mouse |
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.242
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.241
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.238
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.235
|
Human |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.234
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.230
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.228
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.228
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.227
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.227
|
|
|
|
chemokine secretion
|
GO:0090195 |
5 |
0.226
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.225
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.220
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.219
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.215
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.213
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.212
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.212
|
Mouse |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.211
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.206
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.205
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.200
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.200
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.199
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.196
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.195
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.190
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.190
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.182
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.182
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.182
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.181
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.180
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.176
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.175
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.170
|
Mouse |
|
|
detection of fungus
|
GO:0016046 |
2 |
0.169
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.164
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.161
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.161
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.159
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.159
|
Human Mouse |
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.158
|
Mouse |
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.156
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.156
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.155
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.152
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.151
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.150
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.150
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.148
|
Mouse |
|
|
positive regulation of toll like receptor 9 signaling pathway
|
GO:0034165 |
2 |
0.148
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.147
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.146
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.146
|
Mouse |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.146
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.145
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.145
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.144
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.143
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.143
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.142
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.140
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.139
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.139
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.139
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.137
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.137
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.136
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.136
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.135
|
Mouse |
|
|
chemokine metabolic process
|
GO:0050755 |
10 |
0.135
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.134
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.133
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.133
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.132
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.132
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.130
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.130
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.130
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.129
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.129
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.128
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.127
|
Mouse |
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.126
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.125
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.125
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.124
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.123
|
Mouse |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.123
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.123
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.122
|
Mouse |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.122
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.122
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.121
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.120
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.120
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.120
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.119
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.118
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.115
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.115
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.114
|
Human Mouse |
|
|
regulation of thymocyte apoptotic process
|
GO:0070243 |
14 |
0.114
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.114
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.113
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.113
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.112
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.112
|
|
|
|
response to atp
|
GO:0033198 |
8 |
0.111
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.110
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.110
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.109
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.109
|
Mouse |
|
|
serotonin secretion by mast cell
|
GO:0002552 |
1 |
0.109
|
|
|
|
interleukin 33 mediated signaling pathway
|
GO:0038172 |
1 |
0.108
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.107
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.107
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.107
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.106
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.106
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.106
|
Mouse |
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.105
|
Mouse |
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.105
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.105
|
Mouse |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.105
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.104
|
|
|
|
regulation of adiponectin secretion
|
GO:0070163 |
2 |
0.104
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.103
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.103
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.102
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.102
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.102
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.101
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.101
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.100
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.099
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.099
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.098
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.098
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.097
|
Human |
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.097
|
Mouse |
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.097
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.095
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.094
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.094
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.091
|
Mouse |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.091
|
Mouse |
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.091
|
|
|
|
positive regulation of interleukin 1 alpha secretion
|
GO:0050717 |
3 |
0.090
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.090
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.089
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.089
|
Human Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.089
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.088
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.087
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.087
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.087
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.087
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.087
|
Human |
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.086
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.086
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.086
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.086
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.085
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.085
|
|
|
|
regulation of interleukin 1 alpha production
|
GO:0032650 |
4 |
0.084
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.083
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.083
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.083
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.083
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.081
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.080
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.080
|
Mouse |
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.080
|
Mouse |
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.080
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.080
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.080
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.080
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.079
|
Human |
|
|
chemokine production
|
GO:0032602 |
34 |
0.079
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.078
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
9 |
0.078
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.078
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.078
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.077
|
|
|
|
negative regulation of activated t cell proliferation
|
GO:0046007 |
7 |
0.077
|
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.077
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.077
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.076
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.076
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.076
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.076
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.075
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.075
|
Mouse |
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.075
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.075
|
Mouse |
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.075
|
Human |
|
|
t cell migration
|
GO:0072678 |
19 |
0.075
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.075
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
14 |
0.075
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.074
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.074
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.074
|
Mouse |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.074
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.074
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.074
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.073
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.073
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.073
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.073
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.073
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.073
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.073
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.073
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.072
|
|
|
|
negative regulation of mast cell degranulation
|
GO:0043305 |
4 |
0.072
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.071
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.071
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.071
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.071
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.070
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.070
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.070
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.069
|
Human |
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.069
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.069
|
Mouse |
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.069
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.068
|
Mouse |
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.068
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.068
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.068
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.068
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.067
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.067
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.067
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.067
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.066
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.066
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
15 |
0.066
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.066
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.066
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.065
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.064
|
|
|
|
regulation of interleukin 1 alpha secretion
|
GO:0050705 |
3 |
0.064
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.064
|
Mouse |
|
|
regulation of action potential
|
GO:0098900 |
4 |
0.064
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.063
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.063
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.063
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.062
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.061
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.061
|
Human |
|
|
negative regulation of chemokine biosynthetic process
|
GO:0045079 |
2 |
0.061
|
|
|
|
pyroptosis
|
GO:0070269 |
8 |
0.060
|
|
|
|
response to host defenses
|
GO:0052200 |
3 |
0.060
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.060
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.059
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.059
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.059
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.059
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.059
|
Mouse |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.058
|
|
|
|
positive regulation of interleukin 1 alpha production
|
GO:0032730 |
4 |
0.058
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.058
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.058
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.057
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.057
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.057
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.057
|
Mouse |
|
|
ectopic germ cell programmed cell death
|
GO:0035234 |
9 |
0.056
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.056
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.056
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.056
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.056
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.056
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.055
|
|
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
3 |
0.055
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.055
|
Mouse |
|
|
dna recombination
|
GO:0006310 |
92 |
0.055
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.055
|
Mouse |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.055
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.055
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.055
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.054
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.054
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.054
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.054
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.054
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.054
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.054
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.053
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.053
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.053
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.053
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.053
|
Mouse |
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.053
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
108 |
0.052
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.051
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.051
|
Human Mouse |
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.051
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.051
|
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
13 |
0.050
|
|
|
|
negative regulation of myeloid dendritic cell activation
|
GO:0030886 |
3 |
0.050
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.050
|
Human |
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.050
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.049
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.049
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.049
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.048
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.048
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.048
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.048
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.048
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.048
|
|
|
|
adiponectin secretion
|
GO:0070162 |
2 |
0.048
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.048
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.047
|
Mouse |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.047
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.047
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.047
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
3 |
0.047
|
|
|
|
cellular response to interferon beta
|
GO:0035458 |
21 |
0.047
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.047
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.047
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
8 |
0.047
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.046
|
Mouse |
|
|
regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002877 |
2 |
0.046
|
|
|
|
purinergic receptor signaling pathway
|
GO:0035587 |
7 |
0.046
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.046
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.046
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.046
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.046
|
|
|
|
chronic inflammatory response to antigenic stimulus
|
GO:0002439 |
3 |
0.045
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.045
|
|
|
|
positive regulation of interleukin 6 secretion
|
GO:2000778 |
1 |
0.045
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.045
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.044
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.044
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.044
|
Mouse |
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.044
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.044
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.044
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.044
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.044
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.043
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.043
|
Mouse |
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.043
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.043
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.043
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.043
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.043
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.043
|
Human |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.043
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.042
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.042
|
|
|
|
neutrophil mediated killing of symbiont cell
|
GO:0070943 |
8 |
0.042
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.042
|
|
|
|
positive regulation of hemostasis
|
GO:1900048 |
10 |
0.042
|
|
|
|
detection of lipopolysaccharide
|
GO:0032497 |
1 |
0.042
|
|
|
|
positive regulation of neutrophil mediated killing of symbiont cell
|
GO:0070961 |
1 |
0.041
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
20 |
0.041
|
Human |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.041
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.041
|
Mouse |
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.041
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.041
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.041
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.041
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.041
|
Mouse |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.041
|
|
