IMP

Process View

Mus musculus

15 genes annotated in mouse

Multi-species View

interleukin 2 biosynthetic process

GO:0042094

The chemical reactions and pathways resulting in the formation of interleukin-2.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 2 biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "interleukin 2 biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Stat5b	signal transducer and activator of transcription 5B	0.981
Foxp3	forkhead box P3	0.955
Stat5a	signal transducer and activator of transcription 5A	0.945
Il1r1	interleukin 1 receptor, type I	0.896	Mouse
Cd80	CD80 antigen	0.794
Il6	interleukin 6	0.541
Tnf	tumor necrosis factor	0.403
Irf9	interferon regulatory factor 9	0.399
Stat3	signal transducer and activator of transcription 3	0.372	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.283
Sh2d1a	SH2 domain protein 1A	0.278
Nlrp3	NLR family, pyrin domain containing 3	0.276
Il1b	interleukin 1 beta	0.274	Human
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.228
Il27ra	interleukin 27 receptor, alpha	0.217
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.186
Il1a	interleukin 1 alpha	0.181	Human
Batf	basic leucine zipper transcription factor, ATF-like	0.172
Il6st	interleukin 6 signal transducer	0.165
Il4	interleukin 4	0.140
Stat6	signal transducer and activator of transcription 6	0.138	Mouse
Icos	inducible T-cell co-stimulator	0.133	Mouse
Cd5	CD5 antigen	0.132
Il10	interleukin 10	0.129
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.125	Mouse
Il4ra	interleukin 4 receptor, alpha	0.123
Ccr2	chemokine (C-C motif) receptor 2	0.120
Pdcd1	programmed cell death 1	0.103
Gli2	GLI-Kruppel family member GLI2	0.093
Cd7	CD7 antigen	0.093
Akt1	thymoma viral proto-oncogene 1	0.092	Mouse
Cd6	CD6 antigen	0.091
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.083
Arid1b	AT rich interactive domain 1B (SWI-like)	0.082
Fasl	Fas ligand (TNF superfamily, member 6)	0.080
Il2ra	interleukin 2 receptor, alpha chain	0.080
Il1rl1	interleukin 1 receptor-like 1	0.078	Mouse
Cd28	CD28 antigen	0.077
Trim21	tripartite motif-containing 21	0.077
Prlr	prolactin receptor	0.076
Ptgs2	prostaglandin-endoperoxide synthase 2	0.073
Traf1	TNF receptor-associated factor 1	0.072
Nckap1l	NCK associated protein 1 like	0.070
Cxcr6	chemokine (C-X-C motif) receptor 6	0.067
Ccr7	chemokine (C-C motif) receptor 7	0.067
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.066
Socs1	suppressor of cytokine signaling 1	0.065
Fas	Fas (TNF receptor superfamily member 6)	0.062
Sell	selectin, lymphocyte	0.062
Gimap7	GTPase, IMAP family member 7	0.057
Pparg	peroxisome proliferator activated receptor gamma	0.057
Ghr	growth hormone receptor	0.055
Il2rb	interleukin 2 receptor, beta chain	0.053
Ifng	interferon gamma	0.050
Prf1	perforin 1 (pore forming protein)	0.050
Prkcq	protein kinase C, theta	0.049
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.049
Il33	interleukin 33	0.041
Lepr	leptin receptor	0.041
Xcl1	chemokine (C motif) ligand 1	0.040
Il1r2	interleukin 1 receptor, type II	0.037	Mouse
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.036
Mmp12	matrix metallopeptidase 12	0.036
Il18r1	interleukin 18 receptor 1	0.036	Mouse
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.035
Rc3h1	RING CCCH (C3H) domains 1	0.034
Nfil3	nuclear factor, interleukin 3, regulated	0.034
Akt2	thymoma viral proto-oncogene 2	0.032	Mouse
Clec4n	C-type lectin domain family 4, member n	0.031
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.031
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.031
Il1rap	interleukin 1 receptor accessory protein	0.030
Rel	reticuloendotheliosis oncogene	0.030
Cxcl9	chemokine (C-X-C motif) ligand 9	0.029
Sh2d2a	SH2 domain protein 2A	0.029
Itk	IL2-inducible T-cell kinase	0.028
Il2	interleukin 2	0.027
Gzma	granzyme A	0.027
Ubd	ubiquitin D	0.026
Cd3d	CD3 antigen, delta polypeptide	0.026	Mouse
Gbp1	guanylate binding protein 1	0.025
Mobp	myelin-associated oligodendrocytic basic protein	0.023
Ccrl2	chemokine (C-C motif) receptor-like 2	0.023
Ttc7	tetratricopeptide repeat domain 7	0.023
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.022
Ahr	aryl-hydrocarbon receptor	0.022
Mapkapk2	MAP kinase-activated protein kinase 2	0.021
Ar	androgen receptor	0.021
Rhoh	ras homolog gene family, member H	0.021
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.021
Rgs1	regulator of G-protein signaling 1	0.021
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.021
Clec4e	C-type lectin domain family 4, member e	0.020
Btk	Bruton agammaglobulinemia tyrosine kinase	0.020
Asprv1	aspartic peptidase, retroviral-like 1	0.020
Cd3e	CD3 antigen, epsilon polypeptide	0.020
Tlr4	toll-like receptor 4	0.020
Smad4	MAD homolog 4 (Drosophila)	0.019
Hpgds	hematopoietic prostaglandin D synthase	0.019
Plp1	proteolipid protein (myelin) 1	0.019
Capn1	calpain 1	0.019
Il21r	interleukin 21 receptor	0.019
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.018
Ikzf3	IKAROS family zinc finger 3	0.018
Il18rap	interleukin 18 receptor accessory protein	0.018	Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.018
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.018
Cxcr2	chemokine (C-X-C motif) receptor 2	0.018
Lif	leukemia inhibitory factor	0.018
Stx11	syntaxin 11	0.018
Pdcd1lg2	programmed cell death 1 ligand 2	0.017	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.017
Parp14	poly (ADP-ribose) polymerase family, member 14	0.017
LOC677008	natural killer cell receptor 2B4-like	0.017
Ccl4	chemokine (C-C motif) ligand 4	0.017
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.016
Gfi1	growth factor independent 1	0.016
Trp53	transformation related protein 53	0.016
Cst7	cystatin F (leukocystatin)	0.016
Lcp2	lymphocyte cytosolic protein 2	0.016
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.016
Gzmb	granzyme B	0.015
Ccl22	chemokine (C-C motif) ligand 22	0.015
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.015
Fpr2	formyl peptide receptor 2	0.015
Cd40	CD40 antigen	0.015
Smad1	MAD homolog 1 (Drosophila)	0.015
Cd96	CD96 antigen	0.015
Ccr9	chemokine (C-C motif) receptor 9	0.015
Gbp6	guanylate binding protein 6	0.014
Tollip	toll interacting protein	0.014
Cxcl2	chemokine (C-X-C motif) ligand 2	0.014
Inhba	inhibin beta-A	0.014
Ncoa3	nuclear receptor coactivator 3	0.014
Foxo1	forkhead box O1	0.014
Smad3	MAD homolog 3 (Drosophila)	0.013
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.013
Itgae	integrin alpha E, epithelial-associated	0.013
Birc3	baculoviral IAP repeat-containing 3	0.013
Crb2	crumbs homolog 2 (Drosophila)	0.013
Cd8a	CD8 antigen, alpha chain	0.013
Ccl3	chemokine (C-C motif) ligand 3	0.013
Tapbpl	TAP binding protein-like	0.013
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.012
Cd160	CD160 antigen	0.012
Stap1	signal transducing adaptor family member 1	0.012
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.012
Il10ra	interleukin 10 receptor, alpha	0.012
Ctsw	cathepsin W	0.012
Lta	lymphotoxin A	0.012
Spna1	spectrin alpha 1	0.012
Irf4	interferon regulatory factor 4	0.011	Human
Ifnar2	interferon (alpha and beta) receptor 2	0.011
Naip6	NLR family, apoptosis inhibitory protein 6	0.011
Socs2	suppressor of cytokine signaling 2	0.011
Has2	hyaluronan synthase 2	0.011
Txk	TXK tyrosine kinase	0.011
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.011
Sp110	Sp110 nuclear body protein	0.011
Ccl24	chemokine (C-C motif) ligand 24	0.011
Ldb3	LIM domain binding 3	0.011
Casp1	caspase 1	0.010
Slamf6	SLAM family member 6	0.010
Zap70	zeta-chain (TCR) associated protein kinase	0.010
Wrn	Werner syndrome homolog (human)	0.010
Cd27	CD27 antigen	0.010
BC021614	cDNA sequence BC021614	0.010