Mus musculus

48 known processes

Nphp4

nephronophthisis 4 (juvenile) homolog (human)

(Aliases: 4930564O18Rik,nmf192)

Nphp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intermediate filament organization GO:0045109 15 0.998
intermediate filament cytoskeleton organization GO:0045104 26 0.989
intermediate filament bundle assembly GO:0045110 3 0.985
microtubule based process GO:0007017 236 0.980
protein refolding GO:0042026 1 0.961
retina homeostasis GO:0001895 23 0.960
cell cell recognition GO:0009988 44 0.959
peripheral nervous system axon regeneration GO:0014012 2 0.950
keratinocyte development GO:0003334 10 0.941
microtubule based movement GO:0007018 84 0.938
regulation of epidermal cell differentiation GO:0045604 21 0.921
wound healing GO:0042060 157 0.908
microtubule cytoskeleton organization GO:0000226 157 0.906
sperm egg recognition GO:0035036 37 0.879
single fertilization GO:0007338 82 0.861
axon guidance GO:0007411 141 0.848
binding of sperm to zona pellucida GO:0007339 34 0.831
tubulin complex biogenesis GO:0072668 2 0.829
regulation of schwann cell proliferation GO:0010624 2 0.824
keratinocyte differentiation GO:0030216 48 0.818
schwann cell proliferation GO:0014010 2 0.808
regulation of body fluid levels GO:0050878 162 0.790
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.783
protein transmembrane transport GO:0071806 8 0.780
regulation of transferase activity GO:0051338 263 0.773
locomotory behavior GO:0007626 195 0.770
Worm
intermediate filament based process GO:0045103 27 0.768
spindle assembly GO:0051225 13 0.757
protein targeting to mitochondrion GO:0006626 6 0.720
hair follicle morphogenesis GO:0031069 29 0.713
epidermis development GO:0008544 187 0.708
response to radiation GO:0009314 165 0.699
mitochondrion organization GO:0007005 134 0.698
multicellular organismal water homeostasis GO:0050891 23 0.697
positive regulation of glial cell proliferation GO:0060252 4 0.675
camera type eye development GO:0043010 266 0.664
regulation of keratinocyte differentiation GO:0045616 11 0.659
neuron projection guidance GO:0097485 141 0.647
cellular response to topologically incorrect protein GO:0035967 25 0.641
response to uv a GO:0070141 1 0.633
response to light stimulus GO:0009416 135 0.632
transmembrane transport GO:0055085 412 0.623
photoreceptor cell differentiation GO:0046530 52 0.623
regulation of transposition GO:0010528 2 0.621
neurofilament cytoskeleton organization GO:0060052 10 0.610
photoreceptor cell development GO:0042461 40 0.610
protein processing GO:0016485 163 0.609
fertilization GO:0009566 127 0.605
lens development in camera type eye GO:0002088 62 0.600
response to topologically incorrect protein GO:0035966 25 0.579
cell recognition GO:0008037 83 0.575
urogenital system development GO:0001655 261 0.561
protein maturation GO:0051604 176 0.550
organelle assembly GO:0070925 177 0.549
Worm
nonmotile primary cilium assembly GO:0035058 8 0.536
Worm
cellular response to interleukin 4 GO:0071353 21 0.535
negative regulation of apoptotic signaling pathway GO:2001234 104 0.534
vesicle uncoating GO:0072319 4 0.526
positive regulation of lipid kinase activity GO:0090218 11 0.519
regulation of water loss via skin GO:0033561 16 0.517
cytoskeleton dependent intracellular transport GO:0030705 50 0.498
response to interleukin 4 GO:0070670 23 0.490
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.486
striatal medium spiny neuron differentiation GO:0021773 2 0.486
axon cargo transport GO:0008088 33 0.472
lens morphogenesis in camera type eye GO:0002089 24 0.468
chemotaxis GO:0006935 247 0.460
phospholipid metabolic process GO:0006644 87 0.454
water homeostasis GO:0030104 27 0.444
positive regulation of transferase activity GO:0051347 167 0.439
skin development GO:0043588 220 0.436
positive regulation of glutamate receptor signaling pathway GO:1900451 3 0.428
cilium assembly GO:0042384 81 0.428
Worm
microtubule based transport GO:0010970 50 0.428
layer formation in cerebral cortex GO:0021819 13 0.425
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.425
establishment of protein localization to mitochondrion GO:0072655 11 0.424
response to temperature stimulus GO:0009266 55 0.418
cellular lipid metabolic process GO:0044255 323 0.414
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.413
regulation of cysteine type endopeptidase activity GO:2000116 65 0.408
photoreceptor cell maintenance GO:0045494 19 0.403
thermosensory behavior GO:0040040 1 0.395
peripheral nervous system neuron axonogenesis GO:0048936 3 0.374
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.368
dendritic spine development GO:0060996 30 0.365
epithelial cell development GO:0002064 159 0.363
protein import into nucleus translocation GO:0000060 12 0.359
regeneration GO:0031099 38 0.344
keratinization GO:0031424 9 0.338
multicellular organismal homeostasis GO:0048871 164 0.308
cell type specific apoptotic process GO:0097285 268 0.306
regulation of epidermis development GO:0045682 33 0.298
skin morphogenesis GO:0043589 38 0.283
regulation of dendritic spine morphogenesis GO:0061001 17 0.277
epithelium migration GO:0090132 63 0.276
spermatogenesis GO:0007283 284 0.269
positive regulation of gene silencing by mirna GO:2000637 1 0.268
regulation of synaptic plasticity GO:0048167 87 0.260
molting cycle GO:0042303 90 0.256
positive regulation of dendrite development GO:1900006 21 0.249
cellular response to cytokine stimulus GO:0071345 189 0.248
regulation of axon diameter GO:0031133 6 0.247
positive regulation of cell projection organization GO:0031346 95 0.239
protein targeting to er GO:0045047 2 0.239
regulation of cell projection size GO:0032536 6 0.236
motor neuron migration GO:0097475 4 0.230
regulation of long term synaptic depression GO:1900452 3 0.223
epithelial cell migration GO:0010631 63 0.221
posttranscriptional regulation of gene expression GO:0010608 155 0.216
regulation of protein kinase activity GO:0045859 232 0.215
establishment of endothelial blood brain barrier GO:0014045 3 0.211
proteasome assembly GO:0043248 1 0.209
cilium morphogenesis GO:0060271 102 0.206
Worm
microtubule organizing center organization GO:0031023 28 0.205
negative regulation of transferase activity GO:0051348 85 0.204
defecation GO:0030421 1 0.201
negative regulation of cellular component organization GO:0051129 194 0.200
nuclear transport GO:0051169 139 0.199
mitochondrial transport GO:0006839 36 0.197
organelle disassembly GO:1903008 2 0.197
positive regulation of kinase activity GO:0033674 155 0.193
actin cytoskeleton organization GO:0030036 220 0.187
establishment of skin barrier GO:0061436 14 0.186
long term synaptic potentiation GO:0060291 25 0.186
protein localization to mitochondrion GO:0070585 15 0.183
regulation of kinase activity GO:0043549 249 0.182
digestive system development GO:0055123 200 0.181
actin filament based movement GO:0030048 23 0.179
actin mediated cell contraction GO:0070252 15 0.179
establishment of protein localization to organelle GO:0072594 118 0.177
regulation of gliogenesis GO:0014013 50 0.177
regulation of synaptic vesicle priming GO:0010807 4 0.172
regulation of canonical wnt signaling pathway GO:0060828 82 0.171
kidney development GO:0001822 213 0.170
striated muscle myosin thick filament assembly GO:0071688 1 0.170
regulation of neuron migration GO:2001222 22 0.167
positive regulation of lipid metabolic process GO:0045834 40 0.166
zymogen activation GO:0031638 41 0.164
extrinsic apoptotic signaling pathway GO:0097191 126 0.163
meiotic nuclear division GO:0007126 115 0.159
organophosphate catabolic process GO:0046434 232 0.157
epidermis morphogenesis GO:0048730 33 0.156
regulation of lipid kinase activity GO:0043550 14 0.155
regulation of protein serine threonine kinase activity GO:0071900 157 0.154
regulation of lipid metabolic process GO:0019216 118 0.152
anatomical structure homeostasis GO:0060249 145 0.152
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.151
midgut development GO:0007494 4 0.143
negative regulation of inclusion body assembly GO:0090084 1 0.138
ribonucleoside monophosphate catabolic process GO:0009158 57 0.136
wnt signaling pathway GO:0016055 188 0.136
positive regulation of cell growth GO:0030307 33 0.134
lateral ventricle development GO:0021670 11 0.133
regulation of blood volume by renin angiotensin GO:0002016 7 0.133
positive regulation of creb transcription factor activity GO:0032793 4 0.131
neuron migration GO:0001764 122 0.129
circulatory system process GO:0003013 197 0.127
thymus development GO:0048538 41 0.126
protein depolymerization GO:0051261 34 0.126
cerebral cortex development GO:0021987 86 0.125
protein import GO:0017038 101 0.125
regulation of endopeptidase activity GO:0052548 89 0.124
ensheathment of neurons GO:0007272 76 0.124
dendritic spine morphogenesis GO:0060997 22 0.124
regulation of cytoskeleton organization GO:0051493 122 0.124
desmosome organization GO:0002934 5 0.121
intracellular protein transport GO:0006886 204 0.120
cerebral cortex radial glia guided migration GO:0021801 17 0.118
apoptotic signaling pathway GO:0097190 306 0.117
cellular component assembly involved in morphogenesis GO:0010927 139 0.114
Worm
clathrin coat assembly GO:0048268 2 0.112
actin filament organization GO:0007015 113 0.112
protein targeting GO:0006605 143 0.111
glutamate receptor signaling pathway GO:0007215 35 0.111
somatic cell dna recombination GO:0016444 51 0.111
substrate dependent cell migration GO:0006929 18 0.108
positive regulation of membrane potential GO:0045838 15 0.107
posttranscriptional gene silencing GO:0016441 10 0.105
neuroblast differentiation GO:0014016 2 0.102
c4 dicarboxylate transport GO:0015740 3 0.099
neuron apoptotic process GO:0051402 142 0.099
cytokine biosynthetic process GO:0042089 68 0.099
negative regulation of transposition GO:0010529 2 0.099
sensory organ morphogenesis GO:0090596 242 0.097
neurotransmitter transport GO:0006836 76 0.096
blood coagulation GO:0007596 76 0.095
axonogenesis GO:0007409 274 0.093
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.093
regulation of defense response GO:0031347 233 0.092
membrane organization GO:0061024 245 0.091
myosin filament organization GO:0031033 3 0.088
tissue regeneration GO:0042246 22 0.087
extracellular structure organization GO:0043062 148 0.086
cytoplasmic transport GO:0016482 234 0.084
mating GO:0007618 27 0.083
Worm
positive regulation of mapk cascade GO:0043410 170 0.081
placenta development GO:0001890 140 0.081
regulation of actin filament bundle assembly GO:0032231 18 0.081
digestive tract morphogenesis GO:0048546 147 0.081
establishment of protein localization to endoplasmic reticulum GO:0072599 2 0.081
cellular protein complex assembly GO:0043623 116 0.080
dna replication GO:0006260 52 0.080
uterus morphogenesis GO:0061038 2 0.078
centrosome cycle GO:0007098 23 0.077
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.076
purine nucleoside monophosphate metabolic process GO:0009126 81 0.076
protein folding GO:0006457 28 0.075
protein targeting to membrane GO:0006612 20 0.075
epithelial cell proliferation GO:0050673 174 0.074
negative regulation of neuron apoptotic process GO:0043524 92 0.074
lipoprotein catabolic process GO:0042159 7 0.073
regulation of organelle organization GO:0033043 289 0.073
cellular response to organic cyclic compound GO:0071407 87 0.072
i kappab kinase nf kappab signaling GO:0007249 85 0.072
regulation of cell cycle GO:0051726 281 0.071
fasciculation of motor neuron axon GO:0097156 2 0.071
triglyceride biosynthetic process GO:0019432 17 0.068
neuromuscular process controlling balance GO:0050885 59 0.068
t cell differentiation in thymus GO:0033077 77 0.068
rna interference GO:0016246 2 0.067
respiratory system development GO:0060541 190 0.067
regulation of cell projection organization GO:0031344 206 0.067
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.066
intrinsic apoptotic signaling pathway GO:0097193 132 0.066
male mating behavior GO:0060179 6 0.066
Worm
dna metabolic process GO:0006259 303 0.065
oocyte anterior posterior axis specification GO:0007314 2 0.065
response to endoplasmic reticulum stress GO:0034976 53 0.065
positive regulation of schwann cell proliferation GO:0010625 1 0.065
polarity specification of proximal distal axis GO:0010085 2 0.064
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.062
smad protein signal transduction GO:0060395 21 0.062
rna dependent dna replication GO:0006278 3 0.062
renal outer medulla development GO:0072054 2 0.062
regulation of glutamate receptor signaling pathway GO:1900449 16 0.060
ventricular system development GO:0021591 27 0.060
protein import into nucleus GO:0006606 95 0.060
multicellular organismal signaling GO:0035637 91 0.060
apoptotic process involved in morphogenesis GO:0060561 25 0.060
regulation of glial cell differentiation GO:0045685 41 0.060
endocytosis GO:0006897 168 0.060
hair follicle development GO:0001942 85 0.060
regulation of epithelial cell proliferation GO:0050678 141 0.059
cellular response to oxidative stress GO:0034599 76 0.058
de novo protein folding GO:0006458 9 0.058
negative regulation of neuron projection regeneration GO:0070571 3 0.058
protein export from nucleus GO:0006611 20 0.058
positive regulation of dendritic spine development GO:0060999 12 0.057
regulation of muscle system process GO:0090257 80 0.057
regulation of myelination GO:0031641 20 0.057
regulation of epithelial to mesenchymal transition GO:0010717 22 0.057
hemostasis GO:0007599 78 0.056
platelet aggregation GO:0070527 20 0.056
leukocyte apoptotic process GO:0071887 71 0.056
response to tumor necrosis factor GO:0034612 26 0.054
positive regulation of neuron projection development GO:0010976 79 0.054
regulation of apoptotic signaling pathway GO:2001233 197 0.053
positive regulation of gliogenesis GO:0014015 27 0.053
lung field specification GO:0060424 3 0.053
regulation of protein import into nucleus GO:0042306 52 0.053
single organismal cell cell adhesion GO:0016337 131 0.052
spinal cord development GO:0021510 81 0.052
endodermal digestive tract morphogenesis GO:0061031 4 0.052
neuromuscular process GO:0050905 99 0.052
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.052
positive regulation of cytoplasmic transport GO:1903651 40 0.052
positive regulation of homeostatic process GO:0032846 64 0.051
macromolecular complex disassembly GO:0032984 43 0.051
regulation of clathrin mediated endocytosis GO:2000369 4 0.051
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.051
purine ribonucleotide catabolic process GO:0009154 208 0.051
purine nucleoside monophosphate catabolic process GO:0009128 58 0.051
positive regulation of protein phosphorylation GO:0001934 242 0.050
regulation of epidermal cell division GO:0010482 3 0.050
atp metabolic process GO:0046034 75 0.050
retina development in camera type eye GO:0060041 119 0.050
axial mesoderm morphogenesis GO:0048319 5 0.050
purine nucleotide metabolic process GO:0006163 302 0.049
peripheral nervous system development GO:0007422 53 0.049
immunoglobulin production GO:0002377 73 0.048
morphogenesis of a branching structure GO:0001763 203 0.048
cardiac cell fate specification GO:0060912 2 0.048
male meiosis GO:0007140 37 0.048
posttranslational protein targeting to membrane GO:0006620 2 0.048
central nervous system vasculogenesis GO:0022009 3 0.048
embryonic eye morphogenesis GO:0048048 29 0.046
regulation of cell size GO:0008361 72 0.046
regulation of protein transport GO:0051223 163 0.046
telomere maintenance via telomerase GO:0007004 1 0.046
canonical wnt signaling pathway GO:0060070 130 0.045
ear development GO:0043583 200 0.045
cellular response to heat GO:0034605 15 0.045
axial mesoderm development GO:0048318 8 0.045
positive regulation of growth GO:0045927 104 0.045
dendritic spine organization GO:0097061 26 0.045
reactive nitrogen species metabolic process GO:2001057 0 0.044
brain morphogenesis GO:0048854 32 0.044
posttranscriptional gene silencing by rna GO:0035194 10 0.044
digestive tract development GO:0048565 190 0.044
protein localization to nucleus GO:0034504 121 0.043
telomere maintenance GO:0000723 19 0.043
tumor necrosis factor biosynthetic process GO:0042533 10 0.043
male gamete generation GO:0048232 285 0.043
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.043
dna catabolic process GO:0006308 19 0.043
determination of adult lifespan GO:0008340 11 0.043
Worm
glial cell proliferation GO:0014009 10 0.043
regulation of transporter activity GO:0032409 57 0.043
regulation of hydrolase activity GO:0051336 246 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.042
action potential GO:0001508 78 0.042
positive regulation of hair cycle GO:0042635 7 0.042
axial mesoderm formation GO:0048320 3 0.042
cellular response to lipid GO:0071396 145 0.042
regulation of cell cycle process GO:0010564 160 0.041
embryonic camera type eye development GO:0031076 36 0.041
4 hydroxyproline metabolic process GO:0019471 5 0.040
synaptic vesicle priming GO:0016082 8 0.040
regulation of neurotransmitter levels GO:0001505 87 0.040
response to yeast GO:0001878 6 0.040
positive regulation of nervous system development GO:0051962 221 0.039
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.039
forebrain development GO:0030900 302 0.039
regulation of long term synaptic potentiation GO:1900271 4 0.039
multicellular organismal aging GO:0010259 24 0.039
Worm
dendrite development GO:0016358 115 0.039
receptor mediated endocytosis GO:0006898 51 0.039
tissue homeostasis GO:0001894 115 0.039
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 9 0.039
telomere maintenance via telomere lengthening GO:0010833 4 0.038
cell cycle g2 m phase transition GO:0044839 20 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
inter male aggressive behavior GO:0002121 3 0.038
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
reactive oxygen species metabolic process GO:0072593 84 0.038
regulation of intracellular transport GO:0032386 159 0.038
endothelial cell migration GO:0043542 44 0.037
nuclear import GO:0051170 95 0.037
fasciculation of sensory neuron axon GO:0097155 3 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
spindle organization GO:0007051 28 0.036
positive regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000969 3 0.036
anion transport GO:0006820 177 0.036
renal system development GO:0072001 225 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
regulation of inflammatory response GO:0050727 147 0.036
response to oxygen levels GO:0070482 62 0.036
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.036
regulation of oxidative stress induced cell death GO:1903201 14 0.036
regulation of cell growth GO:0001558 91 0.035
positive regulation of epidermis development GO:0045684 13 0.035
regulation of protein maturation GO:1903317 96 0.035
response to inorganic substance GO:0010035 96 0.035
response to heat GO:0009408 27 0.035
regulation of system process GO:0044057 200 0.035
cytokine metabolic process GO:0042107 71 0.035
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.034
embryonic placenta development GO:0001892 98 0.034
nephron development GO:0072006 109 0.034
notochord cell development GO:0060035 1 0.034
g0 to g1 transition GO:0045023 3 0.034
regulation of stress activated mapk cascade GO:0032872 69 0.034
regulation of protein targeting GO:1903533 61 0.034
coagulation GO:0050817 78 0.034
negative regulation of protein phosphorylation GO:0001933 126 0.033
leukocyte proliferation GO:0070661 172 0.033
neuron recognition GO:0008038 25 0.033
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.033
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.033
positive regulation of protein modification process GO:0031401 299 0.032
inclusion body assembly GO:0070841 3 0.032
axon ensheathment GO:0008366 76 0.032
renal inner medulla development GO:0072053 3 0.032
connective tissue development GO:0061448 179 0.032
positive regulation of interleukin 1 production GO:0032732 17 0.032
protein localization to plasma membrane GO:0072659 57 0.032
positive regulation of synapse structural plasticity GO:0051835 1 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
postsynaptic membrane organization GO:0001941 18 0.031
response to unfolded protein GO:0006986 21 0.031
regulation of oligodendrocyte differentiation GO:0048713 23 0.031
foregut regionalization GO:0060423 3 0.031
neuronal action potential GO:0019228 54 0.031
pronephros development GO:0048793 5 0.031
positive regulation of interleukin 1 beta production GO:0032731 16 0.031
negative regulation of oxidative stress induced cell death GO:1903202 9 0.031
meiotic cell cycle GO:0051321 122 0.030
blood circulation GO:0008015 195 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
actin filament bundle assembly GO:0051017 40 0.030
negative regulation of organelle organization GO:0010639 90 0.030
pole plasm assembly GO:0007315 2 0.030
olfactory learning GO:0008355 2 0.030
pallium development GO:0021543 120 0.030
regulation of triglyceride metabolic process GO:0090207 17 0.029
long term synaptic depression GO:0060292 13 0.029
regulation of hormone levels GO:0010817 211 0.029
epithelial cell morphogenesis GO:0003382 41 0.029
heart morphogenesis GO:0003007 178 0.029
positive regulation of interferon gamma production GO:0032729 39 0.029
cerebral cortex radially oriented cell migration GO:0021799 31 0.029
regulation of peptidase activity GO:0052547 96 0.028
mesenchymal cell development GO:0014031 93 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.028
positive regulation of striated muscle contraction GO:0045989 3 0.028
regulation of cytokine biosynthetic process GO:0042035 59 0.028
regulation of interleukin 1 beta production GO:0032651 25 0.028
tissue migration GO:0090130 68 0.028
positive regulation of dna replication GO:0045740 9 0.027
protein heterooligomerization GO:0051291 14 0.027
cell maturation GO:0048469 127 0.027
telencephalon cell migration GO:0022029 55 0.027
detection of stimulus GO:0051606 84 0.027
lateral motor column neuron migration GO:0097477 3 0.027
regulation of neuron death GO:1901214 134 0.026
positive regulation of posttranscriptional gene silencing GO:0060148 1 0.026
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.026
cellular homeostasis GO:0019725 240 0.026
regulation of protein localization GO:0032880 231 0.026
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.026
regulation of actin cytoskeleton organization GO:0032956 84 0.026
radial glia guided migration of purkinje cell GO:0021942 6 0.026
regulation of protein import into nucleus translocation GO:0033158 2 0.026
metanephros development GO:0001656 79 0.025
regulation of cell migration GO:0030334 219 0.025
brain renin angiotensin system GO:0002035 5 0.025
calcium ion transport GO:0006816 159 0.025
negative regulation of cellular response to oxidative stress GO:1900408 10 0.025
nucleoside monophosphate catabolic process GO:0009125 59 0.025
response to calcium ion GO:0051592 20 0.025
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.025
endoplasmic reticulum unfolded protein response GO:0030968 19 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
homeostasis of number of cells GO:0048872 210 0.025
epithelial to mesenchymal transition GO:0001837 47 0.025
regulation of receptor activity GO:0010469 41 0.025
transmission of nerve impulse GO:0019226 76 0.024
cellular lipid catabolic process GO:0044242 52 0.024
skeletal myofibril assembly GO:0014866 4 0.024
neurotransmitter uptake GO:0001504 14 0.024
negative regulation of protein processing GO:0010955 79 0.024
hepatocyte apoptotic process GO:0097284 11 0.024
mating behavior GO:0007617 20 0.024
Worm
myelination GO:0042552 74 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
response to organic cyclic compound GO:0014070 198 0.023
regulation of macrophage activation GO:0043030 17 0.023
negative regulation of molecular function GO:0044092 258 0.023
neutral lipid biosynthetic process GO:0046460 18 0.023
er nucleus signaling pathway GO:0006984 27 0.023
regulation of stem cell differentiation GO:2000736 50 0.023
response to cold GO:0009409 19 0.023
myosin filament assembly GO:0031034 2 0.023
positive regulation of cardiac muscle contraction GO:0060452 2 0.023
regulation of homeostatic process GO:0032844 182 0.023
hindbrain morphogenesis GO:0021575 46 0.022
regulation of triglyceride biosynthetic process GO:0010866 10 0.022
regulation of behavioral fear response GO:2000822 2 0.022
negative regulation of hydrolase activity GO:0051346 71 0.022
purine containing compound catabolic process GO:0072523 213 0.022
glycerolipid biosynthetic process GO:0045017 50 0.022
spermatid differentiation GO:0048515 115 0.022
gene silencing GO:0016458 38 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.022
long term memory GO:0007616 15 0.022
uterus development GO:0060065 16 0.022
triglyceride metabolic process GO:0006641 51 0.022
regulation of synapse structural plasticity GO:0051823 4 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
single organism nuclear import GO:1902593 95 0.022
atp catabolic process GO:0006200 55 0.022

Nphp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nephronophthisis DOID:12712 0 0.996
disease of anatomical entity DOID:7 0 0.497
nervous system disease DOID:863 0 0.497
joubert syndrome DOID:0050777 0 0.459
sensory system disease DOID:0050155 0 0.106
eye and adnexa disease DOID:1492 0 0.106
eye disease DOID:5614 0 0.106
neuromuscular disease DOID:440 0 0.085
charcot marie tooth disease DOID:10595 0 0.085
neuropathy DOID:870 0 0.085
central nervous system disease DOID:331 0 0.079
myopathy DOID:423 0 0.047
muscular disease DOID:0080000 0 0.047
heart disease DOID:114 0 0.047
cardiomyopathy DOID:0050700 0 0.047
intrinsic cardiomyopathy DOID:0060036 0 0.047
cardiovascular system disease DOID:1287 0 0.047
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.047
musculoskeletal system disease DOID:17 0 0.047
muscle tissue disease DOID:66 0 0.047
brain disease DOID:936 0 0.029