Mus musculus

237 known processes

Nr1h3

nuclear receptor subfamily 1, group H, member 3

(Aliases: AU018371,RLD1,LXR,Unr1)

Nr1h3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cholesterol homeostasis GO:0042632 44 0.830
acylglycerol homeostasis GO:0055090 16 0.731
sterol homeostasis GO:0055092 45 0.599
lipid homeostasis GO:0055088 63 0.571
cellular lipid metabolic process GO:0044255 323 0.513
glycerolipid metabolic process GO:0046486 122 0.476
Human
triglyceride metabolic process GO:0006641 51 0.431
Human
lipid catabolic process GO:0016042 69 0.390
acylglycerol metabolic process GO:0006639 55 0.381
Human
organic hydroxy compound transport GO:0015850 93 0.351
monocarboxylic acid metabolic process GO:0032787 191 0.316
Human
anion transport GO:0006820 177 0.313
lipid localization GO:0010876 126 0.297
protein lipid complex subunit organization GO:0071825 12 0.265
Mouse
regulation of fatty acid metabolic process GO:0019217 28 0.257
Human
regulation of defense response GO:0031347 233 0.256
regulation of lipoprotein lipase activity GO:0051004 4 0.246
Human
small molecule catabolic process GO:0044282 71 0.246
regulation of cellular ketone metabolic process GO:0010565 66 0.239
Human
regulation of lipid metabolic process GO:0019216 118 0.236
Human
cation transport GO:0006812 399 0.213
innate immune response GO:0045087 157 0.199
response to organic cyclic compound GO:0014070 198 0.192
Human
fatty acid metabolic process GO:0006631 121 0.191
Human
positive regulation of lipid storage GO:0010884 10 0.190
Mouse
regulation of secretion GO:0051046 274 0.183
cellular ketone metabolic process GO:0042180 84 0.182
Human
regulation of homeostatic process GO:0032844 182 0.181
organic acid transport GO:0015849 101 0.181
positive regulation of defense response GO:0031349 124 0.173
Human
carbohydrate derivative biosynthetic process GO:1901137 183 0.173
maintenance of location GO:0051235 89 0.170
response to molecule of bacterial origin GO:0002237 143 0.158
cellular response to hormone stimulus GO:0032870 150 0.157
Rat
triglyceride homeostasis GO:0070328 15 0.153
nucleoside phosphate metabolic process GO:0006753 338 0.153
regulation of cell activation GO:0050865 289 0.152
regulation of cytokine production GO:0001817 266 0.143
regulation of leukocyte differentiation GO:1902105 159 0.141
organ growth GO:0035265 117 0.136
intracellular receptor signaling pathway GO:0030522 74 0.134
camera type eye development GO:0043010 266 0.134
metal ion homeostasis GO:0055065 189 0.132
sterol transport GO:0015918 38 0.131
cholesterol metabolic process GO:0008203 56 0.125
cellular amine metabolic process GO:0044106 44 0.124
amine metabolic process GO:0009308 45 0.123
immune effector process GO:0002252 321 0.123
sterol metabolic process GO:0016125 58 0.122
regulation of lymphocyte activation GO:0051249 240 0.120
cholesterol storage GO:0010878 4 0.119
rhythmic process GO:0048511 174 0.119
regulation of cholesterol homeostasis GO:2000188 9 0.119
organic anion transport GO:0015711 137 0.118
lipid transport GO:0006869 98 0.118
dna metabolic process GO:0006259 303 0.111
carboxylic acid transport GO:0046942 100 0.110
positive regulation of innate immune response GO:0045089 80 0.109
Human
alpha amino acid metabolic process GO:1901605 59 0.108
purine ribonucleotide metabolic process GO:0009150 290 0.108
cellular response to cytokine stimulus GO:0071345 189 0.108
regulation of cellular amino acid metabolic process GO:0006521 5 0.104
response to organonitrogen compound GO:0010243 246 0.104
Rat
regulation of hormone levels GO:0010817 211 0.103
gland development GO:0048732 330 0.103
reactive oxygen species biosynthetic process GO:1903409 8 0.101
cellular chemical homeostasis GO:0055082 215 0.101
regulation of cell migration GO:0030334 219 0.100
protein glycosylation GO:0006486 55 0.099
regulation of membrane potential GO:0042391 192 0.097
nucleobase containing small molecule metabolic process GO:0055086 352 0.096
cyclic nucleotide metabolic process GO:0009187 59 0.095
steroid metabolic process GO:0008202 119 0.093
activation of immune response GO:0002253 138 0.093
Human
synaptic transmission GO:0007268 329 0.090
purine nucleotide metabolic process GO:0006163 302 0.090
positive regulation of cellular amine metabolic process GO:0033240 5 0.088
immune response regulating signaling pathway GO:0002764 125 0.088
Human
transmembrane transport GO:0055085 412 0.088
positive regulation of homeostatic process GO:0032846 64 0.087
Human
carbohydrate metabolic process GO:0005975 230 0.087
leukocyte differentiation GO:0002521 342 0.084
organic acid catabolic process GO:0016054 51 0.084
negative regulation of immune system process GO:0002683 209 0.084
regulation of plasma lipoprotein particle levels GO:0097006 23 0.084
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.084
Human
ribose phosphate metabolic process GO:0019693 291 0.083
nucleotide metabolic process GO:0009117 332 0.083
macromolecule glycosylation GO:0043413 55 0.082
lipid biosynthetic process GO:0008610 179 0.082
Human
organonitrogen compound biosynthetic process GO:1901566 192 0.082
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.081
negative regulation of protein metabolic process GO:0051248 282 0.081
response to peptide hormone GO:0043434 127 0.081
Rat
regulation of body fluid levels GO:0050878 162 0.079
myeloid cell differentiation GO:0030099 233 0.079
cytokine production GO:0001816 319 0.077
purine nucleotide biosynthetic process GO:0006164 65 0.076
regulation of secretion by cell GO:1903530 249 0.076
regulation of cellular catabolic process GO:0031329 242 0.076
alcohol metabolic process GO:0006066 116 0.075
regulation of proteolysis GO:0030162 164 0.075
erythrocyte differentiation GO:0030218 88 0.075
reactive nitrogen species metabolic process GO:2001057 0 0.075
cellular lipid catabolic process GO:0044242 52 0.073
positive regulation of cell death GO:0010942 224 0.073
plasma lipoprotein particle clearance GO:0034381 13 0.073
cell adhesion GO:0007155 329 0.072
g protein coupled receptor signaling pathway GO:0007186 243 0.072
multi multicellular organism process GO:0044706 109 0.072
Worm
bone morphogenesis GO:0060349 78 0.071
spermatogenesis GO:0007283 284 0.070
divalent inorganic cation transport GO:0072511 178 0.069
cholesterol transport GO:0030301 38 0.066
spermatid differentiation GO:0048515 115 0.066
positive regulation of protein modification process GO:0031401 299 0.066
regulation of purine nucleotide metabolic process GO:1900542 169 0.065
response to growth factor GO:0070848 198 0.065
high density lipoprotein particle assembly GO:0034380 3 0.065
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.065
positive regulation of lipid metabolic process GO:0045834 40 0.064
Human
positive regulation of triglyceride lipase activity GO:0061365 3 0.064
Human
regulation of blood pressure GO:0008217 93 0.064
skeletal system morphogenesis GO:0048705 203 0.064
regulation of triglyceride biosynthetic process GO:0010866 10 0.063
Human
hormone secretion GO:0046879 128 0.062
acylglycerol biosynthetic process GO:0046463 18 0.061
Human
fatty acid catabolic process GO:0009062 25 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.061
cardiac muscle tissue development GO:0048738 130 0.061
epithelial cell proliferation GO:0050673 174 0.060
cholesterol efflux GO:0033344 24 0.060
cellular response to lipopolysaccharide GO:0071222 77 0.060
peptidyl amino acid modification GO:0018193 336 0.059
immune response activating signal transduction GO:0002757 116 0.059
Human
cellular amino acid metabolic process GO:0006520 103 0.059
glycosylation GO:0070085 62 0.059
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.059
defense response to other organism GO:0098542 197 0.059
neutral lipid metabolic process GO:0006638 57 0.059
Human
lipoprotein metabolic process GO:0042157 43 0.059
oxidation reduction process GO:0055114 342 0.058
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.057
digestion GO:0007586 40 0.057
epithelial cell development GO:0002064 159 0.055
regulation of response to wounding GO:1903034 189 0.054
myeloid leukocyte differentiation GO:0002573 119 0.054
extracellular structure organization GO:0043062 148 0.054
appendage development GO:0048736 166 0.053
glycoprotein biosynthetic process GO:0009101 89 0.053
blood circulation GO:0008015 195 0.053
t cell activation GO:0042110 289 0.052
positive regulation of transferase activity GO:0051347 167 0.052
positive regulation of cytokine production GO:0001819 174 0.052
negative regulation of nervous system development GO:0051961 156 0.052
response to acid chemical GO:0001101 111 0.052
plasma lipoprotein particle organization GO:0071827 11 0.052
Mouse
carboxylic acid catabolic process GO:0046395 51 0.052
ion transmembrane transport GO:0034220 361 0.052
macromolecule catabolic process GO:0009057 281 0.051
lymphocyte differentiation GO:0030098 242 0.051
female sex differentiation GO:0046660 84 0.051
purine containing compound metabolic process GO:0072521 311 0.051
drug catabolic process GO:0042737 2 0.049
purine containing compound biosynthetic process GO:0072522 70 0.049
glycoprotein metabolic process GO:0009100 116 0.048
regulation of ion transport GO:0043269 215 0.048
regulation of lymphocyte mediated immunity GO:0002706 84 0.048
monocarboxylic acid transport GO:0015718 44 0.048
cation homeostasis GO:0055080 212 0.048
cholesterol esterification GO:0034435 3 0.048
embryonic appendage morphogenesis GO:0035113 126 0.047
regulation of mapk cascade GO:0043408 248 0.047
lipid modification GO:0030258 65 0.047
cellular response to organonitrogen compound GO:0071417 145 0.047
Rat
calcium ion homeostasis GO:0055074 127 0.047
negative regulation of cell development GO:0010721 169 0.046
cellular water homeostasis GO:0009992 2 0.046
positive regulation of sterol transport GO:0032373 9 0.046
bone development GO:0060348 120 0.046
cellular ion homeostasis GO:0006873 165 0.045
cellular response to biotic stimulus GO:0071216 92 0.045
divalent metal ion transport GO:0070838 172 0.045
regulation of reproductive process GO:2000241 66 0.045
positive regulation of lipoprotein lipase activity GO:0051006 3 0.045
Human
regulation of organelle organization GO:0033043 289 0.044
membrane organization GO:0061024 245 0.044
production of molecular mediator of immune response GO:0002440 103 0.044
ossification GO:0001503 216 0.044
urogenital system development GO:0001655 261 0.043
anatomical structure homeostasis GO:0060249 145 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.043
Rat
cytoplasmic transport GO:0016482 234 0.043
organophosphate biosynthetic process GO:0090407 122 0.043
germ cell development GO:0007281 185 0.042
cellular macromolecule catabolic process GO:0044265 206 0.042
endocytosis GO:0006897 168 0.042
Human
lipid storage GO:0019915 36 0.042
positive regulation of camp mediated signaling GO:0043950 3 0.042
extrinsic apoptotic signaling pathway GO:0097191 126 0.041
response to extracellular stimulus GO:0009991 127 0.041
protein localization to organelle GO:0033365 185 0.041
regulation of cellular amine metabolic process GO:0033238 20 0.040
female gonad development GO:0008585 71 0.040
regulation of system process GO:0044057 200 0.040
neuron migration GO:0001764 122 0.040
sequestering of calcium ion GO:0051208 18 0.040
positive regulation of cholesterol transport GO:0032376 9 0.039
cyclic purine nucleotide metabolic process GO:0052652 43 0.039
regulation of triglyceride metabolic process GO:0090207 17 0.039
Human
multicellular organismal homeostasis GO:0048871 164 0.039
positive regulation of apoptotic signaling pathway GO:2001235 95 0.039
response to lipopolysaccharide GO:0032496 128 0.039
positive regulation of lipid transport GO:0032370 22 0.039
nucleotide biosynthetic process GO:0009165 78 0.038
negative regulation of molecular function GO:0044092 258 0.038
positive regulation of triglyceride metabolic process GO:0090208 9 0.038
Human
leukocyte mediated immunity GO:0002443 174 0.038
amino acid transport GO:0006865 61 0.038
cellular calcium ion homeostasis GO:0006874 119 0.038
reverse cholesterol transport GO:0043691 6 0.038
negative regulation of cytokine production GO:0001818 84 0.038
regulation of lipid transport GO:0032368 36 0.038
cellular response to lipid GO:0071396 145 0.037
digestive tract morphogenesis GO:0048546 147 0.037
development of primary sexual characteristics GO:0045137 143 0.037
regulation of cholesterol transport GO:0032374 17 0.037
sterol esterification GO:0034434 3 0.037
limb development GO:0060173 166 0.037
myeloid dendritic cell differentiation GO:0043011 16 0.037
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.037
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.037
phospholipid metabolic process GO:0006644 87 0.037
skeletal system development GO:0001501 356 0.036
ribonucleoside metabolic process GO:0009119 245 0.036
regulation of t cell activation GO:0050863 170 0.036
phospholipid transport GO:0015914 21 0.036
regulation of protein transport GO:0051223 163 0.036
anion transmembrane transport GO:0098656 71 0.036
positive regulation of kinase activity GO:0033674 155 0.036
regulation of protein kinase activity GO:0045859 232 0.036
calcium ion transport GO:0006816 159 0.035
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.035
positive regulation of growth GO:0045927 104 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
ras protein signal transduction GO:0007265 77 0.035
negative regulation of defense response GO:0031348 77 0.034
regulation of transferase activity GO:0051338 263 0.034
cofactor metabolic process GO:0051186 80 0.034
regulation of cellular component biogenesis GO:0044087 181 0.034
Mouse
insulin secretion GO:0030073 89 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
regulation of nucleotide metabolic process GO:0006140 169 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
regulation of intracellular transport GO:0032386 159 0.033
nitrogen compound transport GO:0071705 271 0.033
regulation of innate immune response GO:0045088 91 0.033
Human
purine ribonucleotide biosynthetic process GO:0009152 59 0.033
cellular homeostasis GO:0019725 240 0.033
regulation of adaptive immune response GO:0002819 90 0.033
carboxylic acid biosynthetic process GO:0046394 86 0.032
Human
monocarboxylic acid catabolic process GO:0072329 27 0.032
neuron apoptotic process GO:0051402 142 0.032
regulation of leukocyte proliferation GO:0070663 121 0.032
response to transforming growth factor beta GO:0071559 88 0.032
cellular response to molecule of bacterial origin GO:0071219 83 0.032
gastrulation GO:0007369 116 0.032
response to nutrient levels GO:0031667 109 0.032
leukocyte activation involved in immune response GO:0002366 126 0.031
glycerolipid biosynthetic process GO:0045017 50 0.031
Human
tissue remodeling GO:0048771 102 0.031
regulation of protein localization GO:0032880 231 0.031
male sex differentiation GO:0046661 109 0.031
retina development in camera type eye GO:0060041 119 0.031
negative regulation of protein processing GO:0010955 79 0.031
organic cyclic compound catabolic process GO:1901361 295 0.030
cellular metal ion homeostasis GO:0006875 151 0.030
regulation of leukocyte mediated immunity GO:0002703 104 0.030
regulation of hormone secretion GO:0046883 88 0.030
i kappab kinase nf kappab signaling GO:0007249 85 0.030
regulation of cytokine biosynthetic process GO:0042035 59 0.030
inflammatory response GO:0006954 244 0.030
regulation of female gonad development GO:2000194 7 0.030
regulation of lymphocyte proliferation GO:0050670 117 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
organophosphate ester transport GO:0015748 28 0.029
embryonic limb morphogenesis GO:0030326 126 0.029
myeloid cell homeostasis GO:0002262 114 0.029
anion homeostasis GO:0055081 16 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
alcohol biosynthetic process GO:0046165 43 0.029
modification by symbiont of host morphology or physiology GO:0044003 4 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
Human
lymphocyte mediated immunity GO:0002449 139 0.029
regulation of endocytosis GO:0030100 69 0.028
Human
cytokine mediated signaling pathway GO:0019221 115 0.028
regulation of nucleotide biosynthetic process GO:0030808 34 0.028
osteoclast differentiation GO:0030316 62 0.028
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.028
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.028
positive regulation of immune effector process GO:0002699 107 0.028
protein catabolic process GO:0030163 221 0.028
positive regulation of cholesterol homeostasis GO:2000189 2 0.028
Human
connective tissue development GO:0061448 179 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.028
lateral mesoderm morphogenesis GO:0048369 3 0.028
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.028
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
regulation of hydrolase activity GO:0051336 246 0.028
Human
lateral inhibition GO:0046331 1 0.027
steroid esterification GO:0034433 3 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
circadian rhythm GO:0007623 114 0.027
humoral immune response GO:0006959 57 0.027
positive regulation of cell activation GO:0050867 158 0.027
cation transmembrane transport GO:0098655 266 0.027
regulation of cellular response to stress GO:0080135 159 0.027
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
positive regulation of map kinase activity GO:0043406 84 0.027
regulation of inflammatory response GO:0050727 147 0.027
small molecule biosynthetic process GO:0044283 132 0.027
Human
regulation of tube size GO:0035150 57 0.027
spermatid development GO:0007286 108 0.027
lymphocyte proliferation GO:0046651 164 0.027
regulation of neuron death GO:1901214 134 0.027
drug metabolic process GO:0017144 4 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
toll like receptor signaling pathway GO:0002224 38 0.026
Human
valine metabolic process GO:0006573 4 0.026
fatty acid oxidation GO:0019395 28 0.026
phospholipid homeostasis GO:0055091 6 0.026
intracellular protein transport GO:0006886 204 0.026
cognition GO:0050890 149 0.026
alpha beta t cell activation GO:0046631 91 0.026
short chain fatty acid catabolic process GO:0019626 2 0.026
positive regulation of leukocyte mediated immunity GO:0002705 70 0.026
male gamete generation GO:0048232 285 0.026
forebrain development GO:0030900 302 0.026
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.026
wound healing GO:0042060 157 0.026
amide transport GO:0042886 138 0.026
response to monosaccharide GO:0034284 67 0.025
regulation of lipid biosynthetic process GO:0046890 54 0.025
Human
morphogenesis of a branching structure GO:0001763 203 0.025
neutral lipid biosynthetic process GO:0046460 18 0.025
Human
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
sequestering of metal ion GO:0051238 19 0.025
ribose phosphate biosynthetic process GO:0046390 59 0.025
axonogenesis GO:0007409 274 0.025
gonad development GO:0008406 141 0.025
odontogenesis GO:0042476 78 0.025
female gamete generation GO:0007292 74 0.024
male gonad development GO:0008584 88 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
cell activation involved in immune response GO:0002263 126 0.024
regulation of organ morphogenesis GO:2000027 144 0.024
sulfur compound metabolic process GO:0006790 100 0.024
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.024
Human
regulation of establishment of protein localization GO:0070201 181 0.024
stem cell maintenance GO:0019827 130 0.024
response to vitamin a GO:0033189 1 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
immunoglobulin mediated immune response GO:0016064 69 0.024
development of primary female sexual characteristics GO:0046545 73 0.024
embryonic hemopoiesis GO:0035162 23 0.024
ovarian follicle development GO:0001541 40 0.024
extracellular matrix organization GO:0030198 147 0.024
oogenesis GO:0048477 56 0.024
positive regulation of neuron differentiation GO:0045666 141 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
positive regulation of lipid biosynthetic process GO:0046889 18 0.024
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
regulation of embryonic development GO:0045995 71 0.023
negative regulation of cell motility GO:2000146 61 0.023
phospholipid transfer to membrane GO:0006649 2 0.023
tissue homeostasis GO:0001894 115 0.023
cell type specific apoptotic process GO:0097285 268 0.023
myeloid leukocyte activation GO:0002274 83 0.023
response to steroid hormone GO:0048545 56 0.023
Human
regulation of binding GO:0051098 111 0.023
regulation of lipase activity GO:0060191 15 0.023
Human
glycerolipid catabolic process GO:0046503 16 0.023
defense response to bacterium GO:0042742 119 0.023
intestinal cholesterol absorption GO:0030299 5 0.023
circulatory system process GO:0003013 197 0.023
sensory organ morphogenesis GO:0090596 242 0.023
regulation of t cell proliferation GO:0042129 92 0.023
regulation of fatty acid biosynthetic process GO:0042304 12 0.023
Human
peptidyl tyrosine modification GO:0018212 145 0.023
protein processing GO:0016485 163 0.022
protein localization to vacuole GO:0072665 4 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.022
multicellular organism growth GO:0035264 161 0.022
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.022
blood vessel morphogenesis GO:0048514 285 0.022
regulation of neuron differentiation GO:0045664 281 0.022
lateral mesodermal cell differentiation GO:0048371 3 0.022
regulation of neuron projection development GO:0010975 169 0.022
intestinal epithelial structure maintenance GO:0060729 4 0.022
regulation of ras protein signal transduction GO:0046578 114 0.022
hair follicle development GO:0001942 85 0.022
peptide transport GO:0015833 133 0.022
leukocyte proliferation GO:0070661 172 0.022
hormone mediated signaling pathway GO:0009755 23 0.022
regulation of sterol transport GO:0032371 17 0.022
regulation of protein secretion GO:0050708 82 0.022
glycerophospholipid metabolic process GO:0006650 71 0.022
negative regulation of cell activation GO:0050866 111 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
tolerance induction to self antigen GO:0002513 4 0.021
nitric oxide metabolic process GO:0046209 25 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.021
positive regulation of cytokine biosynthetic process GO:0042108 40 0.021
positive regulation of t cell activation GO:0050870 101 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
lymphocyte activation involved in immune response GO:0002285 93 0.021
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.021
positive regulation of fatty acid metabolic process GO:0045923 8 0.021
Human
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.021
regulation of protein binding GO:0043393 60 0.021
bone resorption GO:0045453 38 0.021
carbohydrate transport GO:0008643 62 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
glucose homeostasis GO:0042593 128 0.020
negative regulation of transferase activity GO:0051348 85 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
protein secretion GO:0009306 111 0.020
response to sterol GO:0036314 4 0.020
chemotaxis GO:0006935 247 0.020
regulation of cell projection organization GO:0031344 206 0.020
regulation of ion homeostasis GO:2000021 64 0.020
regulation of anatomical structure size GO:0090066 178 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of metal ion transport GO:0010959 106 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
response to hyperoxia GO:0055093 2 0.020
sterol transmembrane transport GO:0035382 2 0.020
positive regulation of fatty acid oxidation GO:0046321 4 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
digestive tract development GO:0048565 190 0.020
regulation of map kinase activity GO:0043405 120 0.019
hexose transport GO:0008645 56 0.019
chromatin organization GO:0006325 206 0.019
positive regulation of nervous system development GO:0051962 221 0.019
response to estrogen GO:0043627 24 0.019
regulation of blood vessel size GO:0050880 56 0.019
response to oxygen levels GO:0070482 62 0.019
negative regulation of kinase activity GO:0033673 81 0.019
protein targeting to vacuole GO:0006623 3 0.019
covalent chromatin modification GO:0016569 163 0.019
coagulation GO:0050817 78 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
nuclear division GO:0000280 158 0.019
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.019
embryonic digit morphogenesis GO:0042733 56 0.019
negative regulation of response to wounding GO:1903035 77 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
negative regulation of sterol transport GO:0032372 4 0.019
regulation of t cell differentiation GO:0045580 83 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
positive regulation of secretion by cell GO:1903532 114 0.019
Mouse
response to cholesterol GO:0070723 4 0.019
organic acid biosynthetic process GO:0016053 86 0.019
Human
negative regulation of epithelial cell proliferation GO:0050680 64 0.019
negative regulation of protein transport GO:0051224 46 0.019
actin filament organization GO:0007015 113 0.019
protein homooligomerization GO:0051260 43 0.019
apoptotic signaling pathway GO:0097190 306 0.019
negative regulation of cholesterol transport GO:0032375 4 0.019
regulation of fatty acid beta oxidation GO:0031998 1 0.019
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.018
positive regulation of protein transport GO:0051222 93 0.018
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.018
striated muscle tissue development GO:0014706 293 0.018
regulation of morphogenesis of a branching structure GO:0060688 53 0.018
heart growth GO:0060419 45 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018

Nr1h3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.077
inherited metabolic disorder DOID:655 0 0.068
lipid metabolism disorder DOID:3146 0 0.068
immune system disease DOID:2914 0 0.058
disease of anatomical entity DOID:7 0 0.058
lymphatic system disease DOID:75 0 0.035
nervous system disease DOID:863 0 0.030
central nervous system disease DOID:331 0 0.029
familial hypercholesterolemia DOID:13810 0 0.024
familial hyperlipidemia DOID:1168 0 0.024