IMP

Process View

Mus musculus

10 genes annotated in mouse

positive regulation of lipid storage

Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of lipid storage"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of lipid storage" (in gray)

Name	Description	Probability	Func Analog Organism
Apoe	apolipoprotein E	0.981
Abhd5	abhydrolase domain containing 5	0.906
Lep	leptin	0.893
Vegfa	vascular endothelial growth factor A	0.674
Pparg	peroxisome proliferator activated receptor gamma	0.658
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.640
Cidec	cell death-inducing DFFA-like effector c	0.584	Mouse
Plin1	perilipin 1	0.538
Cav1	caveolin 1, caveolae protein	0.434
Nos3	nitric oxide synthase 3, endothelial cell	0.372
Ghr	growth hormone receptor	0.355
Bcl2	B-cell leukemia/lymphoma 2	0.319
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.300
Apoa1	apolipoprotein A-I	0.299
Adrb3	adrenergic receptor, beta 3	0.228
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.190	Mouse
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.168
Lpl	lipoprotein lipase	0.162
Ldlr	low density lipoprotein receptor	0.161
Wasf2	WAS protein family, member 2	0.155
Tcap	titin-cap	0.154
Ncoa3	nuclear receptor coactivator 3	0.151
Npc1	Niemann Pick type C1	0.138
Cox8b	cytochrome c oxidase, subunit VIIIb	0.120
Lrp1	low density lipoprotein receptor-related protein 1	0.120
Kiss1	KiSS-1 metastasis-suppressor	0.120
Plin4	perilipin 4	0.118
Srf	serum response factor	0.115
Lpin1	lipin 1	0.109
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.100
Pnpla2	patatin-like phospholipase domain containing 2	0.099	Fly
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.095
Adrb2	adrenergic receptor, beta 2	0.090
Fasn	fatty acid synthase	0.081
Otud4	OTU domain containing 4	0.077
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.076
Scd1	stearoyl-Coenzyme A desaturase 1	0.064
Ccl2	chemokine (C-C motif) ligand 2	0.062
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.060
Fabp4	fatty acid binding protein 4, adipocyte	0.058
Nphs2	nephrosis 2 homolog, podocin (human)	0.053
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.050
Hp	haptoglobin	0.049
Plin5	perilipin 5	0.048
Gjb2	gap junction protein, beta 2	0.048
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.046
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.045
Ppara	peroxisome proliferator activated receptor alpha	0.041
Adrb1	adrenergic receptor, beta 1	0.040
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.040
Dhcr7	7-dehydrocholesterol reductase	0.040
2010003K11Rik	RIKEN cDNA 2010003K11 gene	0.037
Por	P450 (cytochrome) oxidoreductase	0.037
Rxrg	retinoid X receptor gamma	0.036
Flii	flightless I homolog (Drosophila)	0.032
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.032
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.030
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.029
Notch2	Notch gene homolog 2 (Drosophila)	0.029
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.028
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.026
Shisa9	shisa homolog 9 (Xenopus laevis)	0.026
Ephx2	epoxide hydrolase 2, cytoplasmic	0.026
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.026
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.026
Lrp10	low-density lipoprotein receptor-related protein 10	0.026
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.026
Fbxo41	F-box protein 41	0.026
Lipe	lipase, hormone sensitive	0.026
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.026
Acacb	acetyl-Coenzyme A carboxylase beta	0.025
Mpped1	metallophosphoesterase domain containing 1	0.025
Fzd4	frizzled homolog 4 (Drosophila)	0.025
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.025
Mapkapk2	MAP kinase-activated protein kinase 2	0.024
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.024
Mt1	metallothionein 1	0.024
Retn	resistin	0.024
Dhcr24	24-dehydrocholesterol reductase	0.023
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.023
Lepr	leptin receptor	0.023
Hpx	hemopexin	0.023
Csrp3	cysteine and glycine-rich protein 3	0.023
Vgll2	vestigial like 2 homolog (Drosophila)	0.022
Bsnd	Bartter syndrome, infantile, with sensorineural deafness (Barttin)	0.022
Hrc	histidine rich calcium binding protein	0.022
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.022
Cfb	complement factor B	0.021
Ranbp9	RAN binding protein 9	0.021
Fgf21	fibroblast growth factor 21	0.021
Gjd3	gap junction protein, delta 3	0.020
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.020
Tlr2	toll-like receptor 2	0.020
Yipf3	Yip1 domain family, member 3	0.020
Angptl4	angiopoietin-like 4	0.020
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.019
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.019
Ninj1	ninjurin 1	0.019
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.019
Gpr26	G protein-coupled receptor 26	0.019
Saa3	serum amyloid A 3	0.018
Tcn2	transcobalamin 2	0.018
Lcat	lecithin cholesterol acyltransferase	0.018
Cd5l	CD5 antigen-like	0.018
Apoc1	apolipoprotein C-I	0.018
Ttn	titin	0.018
Ncf1	neutrophil cytosolic factor 1	0.018
Accn4	amiloride-sensitive cation channel 4, pituitary	0.017
Pcx	pyruvate carboxylase	0.017
F10	coagulation factor X	0.017
Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.017
Nrg4	neuregulin 4	0.017
Grm2	glutamate receptor, metabotropic 2	0.017	Worm
Lgals12	lectin, galactose binding, soluble 12	0.016
Steap4	STEAP family member 4	0.016
Actn2	actinin alpha 2	0.016
Nrap	nebulin-related anchoring protein	0.016
Orm1	orosomucoid 1	0.016
Cd151	CD151 antigen	0.016
Krt79	keratin 79	0.016
Tusc5	tumor suppressor candidate 5	0.016
Htr2a	5-hydroxytryptamine (serotonin) receptor 2A	0.016
Ankrd34a	ankyrin repeat domain 34A	0.016
Hhatl	hedgehog acyltransferase-like	0.016
Epas1	endothelial PAS domain protein 1	0.015
Adipoq	adiponectin, C1Q and collagen domain containing	0.015
Sidt2	SID1 transmembrane family, member 2	0.015
G0s2	G0/G1 switch gene 2	0.015
Hs3st2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	0.015
Clock	circadian locomotor output cycles kaput	0.015
Scarb1	scavenger receptor class B, member 1	0.015	Human Mouse
Pvalb	parvalbumin	0.015
Pcnxl3	pecanex-like 3 (Drosophila)	0.015
Lypd5	Ly6/Plaur domain containing 5	0.015
Il1rn	interleukin 1 receptor antagonist	0.014
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.014
Scd2	stearoyl-Coenzyme A desaturase 2	0.014
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.014
Xdh	xanthine dehydrogenase	0.014
Tbk1	TANK-binding kinase 1	0.014
Men1	multiple endocrine neoplasia 1	0.014
Crat	carnitine acetyltransferase	0.014
Rasgrp2	RAS, guanyl releasing protein 2	0.014
Cdhr5	cadherin-related family member 5	0.014
Ldb3	LIM domain binding 3	0.014
Tmem45b	transmembrane protein 45b	0.014
Slc38a3	solute carrier family 38, member 3	0.013
Myo1c	myosin IC	0.013
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.013
Plbd1	phospholipase B domain containing 1	0.013
Lcn2	lipocalin 2	0.013
Prkci	protein kinase C, iota	0.013
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.013
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.013
Serinc1	serine incorporator 1	0.013
Kpna1	karyopherin (importin) alpha 1	0.013
Dag1	dystroglycan 1	0.013
Myl3	myosin, light polypeptide 3	0.013
Ckm	creatine kinase, muscle	0.012
Tnnt3	troponin T3, skeletal, fast	0.012
Nus1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	0.012
Aldob	aldolase B, fructose-bisphosphate	0.012
Mlxipl	MLX interacting protein-like	0.012
Pcyt2	phosphate cytidylyltransferase 2, ethanolamine	0.012
Mlycd	malonyl-CoA decarboxylase	0.012
Gns	glucosamine (N-acetyl)-6-sulfatase	0.012
Tmem132d	transmembrane protein 132D	0.011
Trim54	tripartite motif-containing 54	0.011
Apoc3	apolipoprotein C-III	0.011
Cpne5	copine V	0.011
Tgm2	transglutaminase 2, C polypeptide	0.011
Fabp1	fatty acid binding protein 1, liver	0.011
Clec4n	C-type lectin domain family 4, member n	0.011
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.011
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.011
Fsd2	fibronectin type III and SPRY domain containing 2	0.011
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
Igfbp1	insulin-like growth factor binding protein 1	0.011
Myof	myoferlin	0.011
C3	complement component 3	0.010	Human
Rap1b	RAS related protein 1b	0.010
Nucb1	nucleobindin 1	0.010
Smagp	small cell adhesion glycoprotein	0.010
Acly	ATP citrate lyase	0.010
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.010
Sh3tc1	SH3 domain and tetratricopeptide repeats 1	0.010
Cyp51	cytochrome P450, family 51	0.010
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.010