Mus musculus

14 known processes

Orai1

ORAI calcium release-activated calcium modulator 1

(Aliases: D730049H07Rik,orai-1,Tmem142a)

Orai1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.773
leukotriene production involved in inflammatory response GO:0002540 2 0.632
ceramide biosynthetic process GO:0046513 20 0.539
leukotriene metabolic process GO:0006691 7 0.492
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.463
regulation of engulfment of apoptotic cell GO:1901074 2 0.432
cellular lipid metabolic process GO:0044255 323 0.378
glycerolipid biosynthetic process GO:0045017 50 0.334
membrane lipid biosynthetic process GO:0046467 32 0.308
glycerolipid metabolic process GO:0046486 122 0.292
fatty acid biosynthetic process GO:0006633 41 0.255
regulation of cell activation GO:0050865 289 0.221
lipoxin a4 biosynthetic process GO:2001303 1 0.212
engulfment of apoptotic cell GO:0043652 3 0.187
adaptive immune response GO:0002250 155 0.180
inflammatory response GO:0006954 244 0.168
lipid biosynthetic process GO:0008610 179 0.166
phosphatidylethanolamine metabolic process GO:0046337 2 0.161
leukotriene biosynthetic process GO:0019370 5 0.161
regulation of vesicle mediated transport GO:0060627 139 0.160
organic acid biosynthetic process GO:0016053 86 0.153
unsaturated fatty acid metabolic process GO:0033559 31 0.141
organophosphate biosynthetic process GO:0090407 122 0.135
endocytosis GO:0006897 168 0.135
protein homotrimerization GO:0070207 4 0.134
fatty acid derivative metabolic process GO:1901568 33 0.132
monocarboxylic acid metabolic process GO:0032787 191 0.131
sphingolipid biosynthetic process GO:0030148 26 0.131
ceramide metabolic process GO:0006672 31 0.128
production of molecular mediator involved in inflammatory response GO:0002532 21 0.128
membrane lipid metabolic process GO:0006643 53 0.126
negative regulation of immune system process GO:0002683 209 0.122
actin cytoskeleton organization GO:0030036 220 0.119
fatty acid derivative biosynthetic process GO:1901570 15 0.116
positive regulation of vasoconstriction GO:0045907 4 0.114
regulation of adaptive immune response GO:0002819 90 0.109
glycerophospholipid metabolic process GO:0006650 71 0.109
monocarboxylic acid biosynthetic process GO:0072330 61 0.108
actin filament organization GO:0007015 113 0.106
membrane organization GO:0061024 245 0.103
carboxylic acid biosynthetic process GO:0046394 86 0.103
response to endoplasmic reticulum stress GO:0034976 53 0.096
phospholipid metabolic process GO:0006644 87 0.095
regulation of body fluid levels GO:0050878 162 0.088
small molecule biosynthetic process GO:0044283 132 0.088
fatty acid metabolic process GO:0006631 121 0.087
icosanoid metabolic process GO:0006690 33 0.086
ossification GO:0001503 216 0.084
negative regulation of adaptive immune response GO:0002820 25 0.082
wound healing GO:0042060 157 0.074
lipoprotein biosynthetic process GO:0042158 33 0.072
phospholipid biosynthetic process GO:0008654 36 0.071
icosanoid biosynthetic process GO:0046456 15 0.070
cellular ketone metabolic process GO:0042180 84 0.068
regulation of cell adhesion GO:0030155 154 0.066
regulation of response to wounding GO:1903034 189 0.066
cytokine production GO:0001816 319 0.065
glycerophospholipid biosynthetic process GO:0046474 32 0.064
circulatory system process GO:0003013 197 0.063
regulation of organelle organization GO:0033043 289 0.063
regulation of cellular ketone metabolic process GO:0010565 66 0.062
regulation of endocytosis GO:0030100 69 0.062
bone mineralization GO:0030282 54 0.061
immune effector process GO:0002252 321 0.060
cellular protein complex assembly GO:0043623 116 0.060
protein lipidation GO:0006497 28 0.059
unsaturated fatty acid biosynthetic process GO:0006636 15 0.059
regulation of anatomical structure size GO:0090066 178 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
regulation of platelet activation GO:0010543 17 0.057
cellular amine metabolic process GO:0044106 44 0.056
heterocycle catabolic process GO:0046700 280 0.056
actin filament polymerization GO:0030041 44 0.056
lipoprotein metabolic process GO:0042157 43 0.055
blood coagulation GO:0007596 76 0.055
ras protein signal transduction GO:0007265 77 0.055
phagocytosis GO:0006909 66 0.054
regulation of cellular component size GO:0032535 121 0.054
regulation of blood coagulation GO:0030193 28 0.054
coagulation GO:0050817 78 0.054
cell adhesion GO:0007155 329 0.049
regulation of secretion GO:0051046 274 0.049
regulation of cellular component biogenesis GO:0044087 181 0.048
negative regulation of cell activation GO:0050866 111 0.048
cellular amino acid metabolic process GO:0006520 103 0.048
intracellular receptor signaling pathway GO:0030522 74 0.047
regulation of system process GO:0044057 200 0.046
regulation of homotypic cell cell adhesion GO:0034110 13 0.045
regulation of blood vessel size GO:0050880 56 0.045
regulation of defense response GO:0031347 233 0.044
regulation of interleukin 6 production GO:0032675 55 0.044
positive regulation of cellular component biogenesis GO:0044089 94 0.044
sensory perception GO:0007600 245 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.043
amine metabolic process GO:0009308 45 0.042
regulation of actin filament based process GO:0032970 99 0.041
long chain fatty acid metabolic process GO:0001676 26 0.041
regulation of blood circulation GO:1903522 93 0.040
endomembrane system organization GO:0010256 147 0.039
lipoxygenase pathway GO:0019372 5 0.038
regulation of intracellular transport GO:0032386 159 0.038
regulation of cytokine production GO:0001817 266 0.038
response to extracellular stimulus GO:0009991 127 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
purine containing compound catabolic process GO:0072523 213 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
regulation of actin filament length GO:0030832 45 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
transmembrane transport GO:0055085 412 0.036
Human
cellular response to inorganic substance GO:0071241 37 0.035
regulation of hemostasis GO:1900046 28 0.035
gland development GO:0048732 330 0.034
regulation of protein kinase activity GO:0045859 232 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.033
ribonucleoside catabolic process GO:0042454 206 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.033
regulation of actin polymerization or depolymerization GO:0008064 45 0.033
mapk cascade GO:0000165 281 0.032
response to hyperoxia GO:0055093 2 0.032
positive regulation of actin filament polymerization GO:0030838 26 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
positive regulation of protein modification process GO:0031401 299 0.032
regulation of tube size GO:0035150 57 0.032
positive regulation of protein complex assembly GO:0031334 45 0.032
vascular process in circulatory system GO:0003018 62 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.031
regulation of mapk cascade GO:0043408 248 0.031
cellular response to calcium ion GO:0071277 14 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
response to inorganic substance GO:0010035 96 0.030
apoptotic signaling pathway GO:0097190 306 0.030
positive regulation of cell activation GO:0050867 158 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
interleukin 6 production GO:0032635 58 0.029
nucleotide metabolic process GO:0009117 332 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
cellular response to molecule of bacterial origin GO:0071219 83 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
regulation of kinase activity GO:0043549 249 0.029
response to nutrient levels GO:0031667 109 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
intracellular protein transport GO:0006886 204 0.028
cellular homeostasis GO:0019725 240 0.028
regulation of homeostatic process GO:0032844 182 0.028
exocytosis GO:0006887 121 0.028
negative regulation of cell adhesion GO:0007162 45 0.028
positive regulation of cytokine production GO:0001819 174 0.028
nitrogen compound transport GO:0071705 271 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
cation transmembrane transport GO:0098655 266 0.028
Human
positive regulation of cell death GO:0010942 224 0.028
gtp metabolic process GO:0046039 144 0.027
response to increased oxygen levels GO:0036296 2 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
myeloid leukocyte activation GO:0002274 83 0.027
ion transmembrane transport GO:0034220 361 0.027
Human
glycosyl compound catabolic process GO:1901658 206 0.027
platelet aggregation GO:0070527 20 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
regulation of transferase activity GO:0051338 263 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
camera type eye development GO:0043010 266 0.025
positive regulation of transferase activity GO:0051347 167 0.025
cytoplasmic transport GO:0016482 234 0.025
striated muscle tissue development GO:0014706 293 0.025
protein oligomerization GO:0051259 67 0.025
negative regulation of protein modification process GO:0031400 163 0.025
regulation of cellular response to stress GO:0080135 159 0.025
biomineral tissue development GO:0031214 64 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
organophosphate catabolic process GO:0046434 232 0.025
leukocyte differentiation GO:0002521 342 0.025
aromatic compound catabolic process GO:0019439 286 0.025
peptidyl amino acid modification GO:0018193 336 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
glycosyl compound metabolic process GO:1901657 246 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
calcium ion transport GO:0006816 159 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
purine containing compound metabolic process GO:0072521 311 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
protein ubiquitination GO:0016567 171 0.023
homotypic cell cell adhesion GO:0034109 28 0.023
macromolecule catabolic process GO:0009057 281 0.023
blood circulation GO:0008015 195 0.023
cell fate commitment GO:0045165 210 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
skin development GO:0043588 220 0.022
regulation of phagocytosis engulfment GO:0060099 5 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
cellular response to lipid GO:0071396 145 0.022
cell activation involved in immune response GO:0002263 126 0.022
compound eye development GO:0048749 1 0.021
t cell differentiation GO:0030217 174 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
Human
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
lateral inhibition GO:0046331 1 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
water homeostasis GO:0030104 27 0.021
cation homeostasis GO:0055080 212 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
innate immune response GO:0045087 157 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
nucleoside catabolic process GO:0009164 206 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
protein localization to plasma membrane GO:0072659 57 0.020
negative regulation of response to wounding GO:1903035 77 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
dna metabolic process GO:0006259 303 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
serotonin secretion involved in inflammatory response GO:0002442 4 0.020
regulation of cell cycle GO:0051726 281 0.020
respiratory tube development GO:0030323 167 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
sensory organ morphogenesis GO:0090596 242 0.020
positive regulation of organelle organization GO:0010638 128 0.019
nucleoside metabolic process GO:0009116 246 0.019
arachidonic acid metabolic process GO:0019369 14 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
spermatogenesis GO:0007283 284 0.019
protein catabolic process GO:0030163 221 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
synaptic transmission GO:0007268 329 0.019
defense response to other organism GO:0098542 197 0.019
spermatid differentiation GO:0048515 115 0.019
actin polymerization or depolymerization GO:0008154 54 0.019
negative regulation of molecular function GO:0044092 258 0.019
sensory perception of pain GO:0019233 47 0.019
vasoconstriction GO:0042310 27 0.019
male gamete generation GO:0048232 285 0.019
stem cell differentiation GO:0048863 268 0.018
organelle localization GO:0051640 179 0.018
response to organonitrogen compound GO:0010243 246 0.018
forebrain development GO:0030900 302 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
leukocyte mediated immunity GO:0002443 174 0.018
response to calcium ion GO:0051592 20 0.018
protein processing GO:0016485 163 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
protein maturation GO:0051604 176 0.018
activation of immune response GO:0002253 138 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
germ cell development GO:0007281 185 0.017
regulation of cell motility GO:2000145 236 0.017
positive regulation of protein transport GO:0051222 93 0.017
chromatin organization GO:0006325 206 0.017
response to oxygen levels GO:0070482 62 0.017
regulated secretory pathway GO:0045055 32 0.017
regulation of exocytosis GO:0017157 61 0.017
single organism cell adhesion GO:0098602 156 0.017
mitotic cell cycle GO:0000278 195 0.017
positive regulation of leukocyte mediated immunity GO:0002705 70 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
negative regulation of protein metabolic process GO:0051248 282 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
multicellular organism growth GO:0035264 161 0.016
myeloid cell differentiation GO:0030099 233 0.016
cellular response to metal ion GO:0071248 31 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
dephosphorylation GO:0016311 129 0.016
protein localization to membrane GO:0072657 108 0.016
regulation of protein processing GO:0070613 96 0.016
regulation of transmembrane transport GO:0034762 128 0.016
cell type specific apoptotic process GO:0097285 268 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
cellular ion homeostasis GO:0006873 165 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
peroxisome proliferator activated receptor signaling pathway GO:0035357 9 0.016
anion transport GO:0006820 177 0.016
b cell activation GO:0042113 161 0.016
positive regulation of secretion GO:0051047 130 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of secretion by cell GO:1903530 249 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
fertilization GO:0009566 127 0.016
regulation of phagocytosis GO:0050764 33 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
Human
positive regulation of blood circulation GO:1903524 22 0.015
regionalization GO:0003002 337 0.015
organic anion transport GO:0015711 137 0.015
response to lipopolysaccharide GO:0032496 128 0.015
immune response activating signal transduction GO:0002757 116 0.015
regulation of production of molecular mediator of immune response GO:0002700 65 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
regulation of ossification GO:0030278 112 0.015
maintenance of location GO:0051235 89 0.015
regulation of protein transport GO:0051223 163 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
homeostasis of number of cells GO:0048872 210 0.015
defense response to bacterium GO:0042742 119 0.015
cation transport GO:0006812 399 0.015
leukocyte degranulation GO:0043299 27 0.015
cellular chemical homeostasis GO:0055082 215 0.015
phagocytosis engulfment GO:0006911 16 0.015
chromatin modification GO:0016568 187 0.015
multicellular organismal water homeostasis GO:0050891 23 0.015
positive regulation of cell development GO:0010720 237 0.015
t cell activation GO:0042110 289 0.015
gtp catabolic process GO:0006184 143 0.015
epithelial cell development GO:0002064 159 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
divalent inorganic cation transport GO:0072511 178 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
regulation of cell projection organization GO:0031344 206 0.015
regulation of ion transmembrane transport GO:0034765 119 0.014
tumor necrosis factor production GO:0032640 50 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
leukocyte homeostasis GO:0001776 79 0.014
urogenital system development GO:0001655 261 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
respiratory system development GO:0060541 190 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
negative regulation of cell cycle GO:0045786 123 0.014
glycoprotein metabolic process GO:0009100 116 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
regulation of multi organism process GO:0043900 111 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
organic hydroxy compound transport GO:0015850 93 0.014
muscle cell development GO:0055001 133 0.014
positive regulation of kinase activity GO:0033674 155 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
protein targeting GO:0006605 143 0.014
membrane invagination GO:0010324 17 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
sphingolipid metabolic process GO:0006665 45 0.014
establishment of vesicle localization GO:0051650 81 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.013
glucose homeostasis GO:0042593 128 0.013
negative regulation of coagulation GO:0050819 11 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
regulation of coagulation GO:0050818 31 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of mast cell activation GO:0033003 21 0.013
cognition GO:0050890 149 0.013
lipid transport GO:0006869 98 0.013
regulation of membrane potential GO:0042391 192 0.013
lipid localization GO:0010876 126 0.013
rho protein signal transduction GO:0007266 32 0.013
blood vessel morphogenesis GO:0048514 285 0.013
negative regulation of cytokine production GO:0001818 84 0.013
skeletal system development GO:0001501 356 0.013
neural tube development GO:0021915 160 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
positive regulation of defense response GO:0031349 124 0.013
transmission of nerve impulse GO:0019226 76 0.013
positive regulation of immune effector process GO:0002699 107 0.012
lung development GO:0030324 164 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
olfactory learning GO:0008355 2 0.012
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
neutrophil chemotaxis GO:0030593 36 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
negative regulation of phagocytosis GO:0050765 4 0.012
regulation of map kinase activity GO:0043405 120 0.012
mitochondrion organization GO:0007005 134 0.012
plasma membrane organization GO:0007009 90 0.012
digestive system development GO:0055123 200 0.012
nucleotide catabolic process GO:0009166 217 0.012
regulation of neuron differentiation GO:0045664 281 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
activation of mapk activity GO:0000187 59 0.012
extracellular matrix organization GO:0030198 147 0.012
response to metal ion GO:0010038 47 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
positive regulation of necrotic cell death GO:0010940 1 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
extracellular structure organization GO:0043062 148 0.012
response to growth factor GO:0070848 198 0.012
carboxylic acid transport GO:0046942 100 0.012
developmental maturation GO:0021700 193 0.012
hormone secretion GO:0046879 128 0.012
learning or memory GO:0007611 148 0.012
regulation of hydrolase activity GO:0051336 246 0.012
negative regulation of nervous system development GO:0051961 156 0.012
regulation of ion transport GO:0043269 215 0.012
Human
axonogenesis GO:0007409 274 0.012
regulation of innate immune response GO:0045088 91 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
gastrulation GO:0007369 116 0.012
cell growth GO:0016049 130 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of t cell activation GO:0050863 170 0.011
negative regulation of cell development GO:0010721 169 0.011
positive regulation of innate immune response GO:0045089 80 0.011
b cell mediated immunity GO:0019724 71 0.011
negative regulation of protein processing GO:0010955 79 0.011
skeletal muscle organ development GO:0060538 163 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
leukocyte migration GO:0050900 124 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
organelle fission GO:0048285 170 0.011
positive regulation of nervous system development GO:0051962 221 0.011
multi multicellular organism process GO:0044706 109 0.011
mitotic cell cycle process GO:1903047 159 0.011
stem cell development GO:0048864 219 0.011
placenta development GO:0001890 140 0.011
mesoderm development GO:0007498 100 0.011
stress activated mapk cascade GO:0051403 80 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
negative regulation of hemostasis GO:1900047 11 0.011
regulation of vasoconstriction GO:0019229 14 0.011
gliogenesis GO:0042063 141 0.011
regulation of proteolysis GO:0030162 164 0.011
pharynx development GO:0060465 1 0.011
serotonin production involved in inflammatory response GO:0002351 4 0.011
regulation of feeding behavior GO:0060259 3 0.011
metal ion homeostasis GO:0055065 189 0.011
positive regulation of adaptive immune response GO:0002821 61 0.011
insulin secretion GO:0030073 89 0.011
microtubule based process GO:0007017 236 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
t cell mediated immunity GO:0002456 50 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
response to acid chemical GO:0001101 111 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
nuclear division GO:0000280 158 0.011
positive regulation of tumor necrosis factor production GO:0032760 30 0.011
telencephalon development GO:0021537 186 0.011
cardiac chamber development GO:0003205 108 0.011
protein localization to organelle GO:0033365 185 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
muscle tissue development GO:0060537 308 0.010
establishment of organelle localization GO:0051656 122 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
response to insulin GO:0032868 100 0.010
locomotory behavior GO:0007626 195 0.010
jnk cascade GO:0007254 72 0.010
myeloid leukocyte mediated immunity GO:0002444 42 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
cellular protein catabolic process GO:0044257 155 0.010
apoptotic cell clearance GO:0043277 17 0.010
response to peptide GO:1901652 136 0.010
osteoclast differentiation GO:0030316 62 0.010
cell substrate adhesion GO:0031589 130 0.010
positive regulation of stress activated mapk cascade GO:0032874 48 0.010
interleukin 8 production GO:0032637 4 0.010
response to peptide hormone GO:0043434 127 0.010
regulation of cytokine production involved in immune response GO:0002718 26 0.010
histone modification GO:0016570 159 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010

Orai1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
cardiovascular system disease DOID:1287 0 0.064
immune system disease DOID:2914 0 0.054
vascular disease DOID:178 0 0.040
artery disease DOID:0050828 0 0.031
nervous system disease DOID:863 0 0.027
musculoskeletal system disease DOID:17 0 0.024
sensory system disease DOID:0050155 0 0.019
hematopoietic system disease DOID:74 0 0.018
connective tissue disease DOID:65 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012