IMP

Process View

Mus musculus

14 genes annotated in mouse

Multi-species View

regulation of vasoconstriction

GO:0019229

Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of vasoconstriction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of vasoconstriction" (in gray)

Name	Description	Probability	Func Analog Organism
Nos3	nitric oxide synthase 3, endothelial cell	0.861
Per2	period homolog 2 (Drosophila)	0.726
Ar	androgen receptor	0.720
Cry2	cryptochrome 2 (photolyase-like)	0.688
Klk1b5	kallikrein 1-related peptidase b5	0.674	Rat
Apc	adenomatosis polyposis coli	0.502
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.478
Lep	leptin	0.450
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.385
Dmd	dystrophin, muscular dystrophy	0.365
Klk1b21	kallikrein 1-related peptidase b21	0.360	Rat
Tgfbr2	transforming growth factor, beta receptor II	0.359	Mouse
Clock	circadian locomotor output cycles kaput	0.298
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.287	Mouse
Mmp9	matrix metallopeptidase 9	0.265
Klk1b26	kallikrein 1-related petidase b26	0.253	Rat
Col4a3	collagen, type IV, alpha 3	0.215
Pgr	progesterone receptor	0.211
Nos1	nitric oxide synthase 1, neuronal	0.194	Rat
Vegfa	vascular endothelial growth factor A	0.178
Klk1b1	kallikrein 1-related peptidase b1	0.140	Rat
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.130
Cav1	caveolin 1, caveolae protein	0.129
Kl	klotho	0.128
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.112	Mouse
Klk1b11	kallikrein 1-related peptidase b11	0.110	Rat
Klk1b8	kallikrein 1-related peptidase b8	0.109	Rat
Csf1	colony stimulating factor 1 (macrophage)	0.105
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.103
Esr1	estrogen receptor 1 (alpha)	0.102
Smad3	MAD homolog 3 (Drosophila)	0.097
Klk1b16	kallikrein 1-related peptidase b16	0.095	Rat
Lepr	leptin receptor	0.090
Cry1	cryptochrome 1 (photolyase-like)	0.088
Vdr	vitamin D receptor	0.085
Tgfbr1	transforming growth factor, beta receptor I	0.078	Mouse
Ptrf	polymerase I and transcript release factor	0.073
Klk1b24	kallikrein 1-related peptidase b24	0.073	Rat
Cd44	CD44 antigen	0.071
Klk1	kallikrein 1	0.071	Rat
Dtna	dystrobrevin alpha	0.064
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.063	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.062
Insr	insulin receptor	0.060
Ptgs2	prostaglandin-endoperoxide synthase 2	0.058	Rat
Ccr2	chemokine (C-C motif) receptor 2	0.058
Per3	period homolog 3 (Drosophila)	0.058	Mouse
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.057	Mouse
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.053
Per1	period homolog 1 (Drosophila)	0.052	Mouse
Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	0.049
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.048
Plau	plasminogen activator, urokinase	0.046
Ren1	renin 1 structural	0.045
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.045
Klk1b27	kallikrein 1-related peptidase b27	0.043	Rat
Neto1	neuropilin (NRP) and tolloid (TLL)-like 1	0.042
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.041
Grid2	glutamate receptor, ionotropic, delta 2	0.041
Lox	lysyl oxidase	0.040
Klk1b4	kallikrein 1-related pepidase b4	0.039	Rat
Ccl2	chemokine (C-C motif) ligand 2	0.038
Tgfbr3	transforming growth factor, beta receptor III	0.037
Klk1b3	kallikrein 1-related peptidase b3	0.035	Rat
Tlr4	toll-like receptor 4	0.034
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.033	Mouse
Nos2	nitric oxide synthase 2, inducible	0.033
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.032
Fgf2	fibroblast growth factor 2	0.032
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.031
Gja1	gap junction protein, alpha 1	0.031	Rat
Arnt	aryl hydrocarbon receptor nuclear translocator	0.031
Socs5	suppressor of cytokine signaling 5	0.031
Cx3cr1	chemokine (C-X3-C) receptor 1	0.031
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.031
Fzd5	frizzled homolog 5 (Drosophila)	0.030
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.028
Plcb1	phospholipase C, beta 1	0.028
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.028
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.027
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.027
Inha	inhibin alpha	0.027
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.026
Tacr1	tachykinin receptor 1	0.026	Rat
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.026
Cnr1	cannabinoid receptor 1 (brain)	0.026
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.025
Fzd8	frizzled homolog 8 (Drosophila)	0.025
Prkg1	protein kinase, cGMP-dependent, type I	0.024
Epas1	endothelial PAS domain protein 1	0.022
Adipoq	adiponectin, C1Q and collagen domain containing	0.022
Klk1b9	kallikrein 1-related peptidase b9	0.022	Rat
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.022
Spp1	secreted phosphoprotein 1	0.021
Ryr1	ryanodine receptor 1, skeletal muscle	0.021
Usp2	ubiquitin specific peptidase 2	0.020
Tgfb2	transforming growth factor, beta 2	0.020
Becn1	beclin 1, autophagy related	0.020
Fbn1	fibrillin 1	0.020
Ids	iduronate 2-sulfatase	0.020
Fzd4	frizzled homolog 4 (Drosophila)	0.019
Ikzf2	IKAROS family zinc finger 2	0.019
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.019
Csnk1e	casein kinase 1, epsilon	0.019
Gab2	growth factor receptor bound protein 2-associated protein 2	0.019
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.018	Mouse
Plat	plasminogen activator, tissue	0.018
Smad1	MAD homolog 1 (Drosophila)	0.018
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.018
Kcnk3	potassium channel, subfamily K, member 3	0.018
Tgfb1	transforming growth factor, beta 1	0.018
Pam	peptidylglycine alpha-amidating monooxygenase	0.018	Mouse
Amigo1	adhesion molecule with Ig like domain 1	0.018
Slc12a1	solute carrier family 12, member 1	0.017
Ednra	endothelin receptor type A	0.017
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.017
Scrg1	scrapie responsive gene 1	0.017
Adora2a	adenosine A2a receptor	0.017
Fxyd2	FXYD domain-containing ion transport regulator 2	0.017
Snta1	syntrophin, acidic 1	0.017
Grb2	growth factor receptor bound protein 2	0.017
Hrh2	histamine receptor H2	0.017
Lmna	lamin A	0.016
Gdnf	glial cell line derived neurotrophic factor	0.016
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.016
Rac1	RAS-related C3 botulinum substrate 1	0.016
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.016	Mouse
Nhedc2	Na+/H+ exchanger domain containing 2	0.016
Gpr12	G-protein coupled receptor 12	0.016
Vcl	vinculin	0.016
Sstr4	somatostatin receptor 4	0.016
Adra2a	adrenergic receptor, alpha 2a	0.016
Ank1	ankyrin 1, erythroid	0.016
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.016
Pcdh12	protocadherin 12	0.015
Shc1	src homology 2 domain-containing transforming protein C1	0.015	Rat
Il16	interleukin 16	0.015
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.015
Gcet2	germinal center expressed transcript 2	0.015
Hbb-b1	hemoglobin, beta adult major chain	0.015
Ptgir	prostaglandin I receptor (IP)	0.015	Mouse
Nxph1	neurexophilin 1	0.014
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.014
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.014	Mouse
Fgf14	fibroblast growth factor 14	0.014
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.014
Mesp1	mesoderm posterior 1	0.014
Tmed8	transmembrane emp24 domain containing 8	0.014
Drd2	dopamine receptor D2	0.014
Akt2	thymoma viral proto-oncogene 2	0.014
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.014
Pdgfb	platelet derived growth factor, B polypeptide	0.014
Ldlr	low density lipoprotein receptor	0.014
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.014
Npas2	neuronal PAS domain protein 2	0.014
Tshr	thyroid stimulating hormone receptor	0.014
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.013
Gsk3b	glycogen synthase kinase 3 beta	0.013
Fmn1	formin 1	0.013
Cckbr	cholecystokinin B receptor	0.013
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.013
Esr2	estrogen receptor 2 (beta)	0.013
Chrm3	cholinergic receptor, muscarinic 3, cardiac	0.013
Bsn	bassoon	0.013
Syn2	synapsin II	0.013
Ptgs1	prostaglandin-endoperoxide synthase 1	0.013	Rat
Myd88	myeloid differentiation primary response gene 88	0.013
Tm4sf1	transmembrane 4 superfamily member 1	0.013
Gpr37l1	G protein-coupled receptor 37-like 1	0.013
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.013
Phkg1	phosphorylase kinase gamma 1	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.013	Mouse
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.013
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.012
Slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.012
Angpt1	angiopoietin 1	0.012
Agtrap	angiotensin II, type I receptor-associated protein	0.012
Acvrl1	activin A receptor, type II-like 1	0.012	Mouse
Ntsr1	neurotensin receptor 1	0.012
Mkl2	MKL/myocardin-like 2	0.012
Ryr2	ryanodine receptor 2, cardiac	0.012
Egfbp2	epidermal growth factor binding protein type B	0.012
Large	like-glycosyltransferase	0.012
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.012
Ccr9	chemokine (C-C motif) receptor 9	0.011
Lefty1	left right determination factor 1	0.011
Sstr3	somatostatin receptor 3	0.011
Nt5e	5' nucleotidase, ecto	0.011
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.011
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.011
Lrrk1	leucine-rich repeat kinase 1	0.011
Try5	trypsin 5	0.011
Osmr	oncostatin M receptor	0.011
Orai1	ORAI calcium release-activated calcium modulator 1	0.011
Il12a	interleukin 12a	0.011
Hr	hairless	0.011
Dlg4	discs, large homolog 4 (Drosophila)	0.011
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.011
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.011
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.011
Padi2	peptidyl arginine deiminase, type II	0.011
Thbd	thrombomodulin	0.011
Ctsl	cathepsin L	0.011
Cdh23	cadherin 23 (otocadherin)	0.011
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.010
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.010
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.010
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.010	Mouse
Fgf23	fibroblast growth factor 23	0.010
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.010
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.010
Smad7	MAD homolog 7 (Drosophila)	0.010
Igf1	insulin-like growth factor 1	0.010
Galr1	galanin receptor 1	0.010
Calcrl	calcitonin receptor-like	0.010
Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	0.010