Mus musculus

152 known processes

Otx2

orthodenticle homolog 2 (Drosophila)

(Aliases: E130306E05Rik)

Otx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
auditory receptor cell fate determination GO:0042668 3 1.000
midbrain hindbrain boundary morphogenesis GO:0021555 4 1.000
motor neuron migration GO:0097475 4 1.000
regionalization GO:0003002 337 1.000
lateral motor column neuron migration GO:0097477 3 1.000
anterior commissure morphogenesis GO:0021960 6 1.000
regulation of rhodopsin gene expression GO:0007468 3 1.000
Fly
cerebral cortex radially oriented cell migration GO:0021799 31 1.000
spinal cord motor neuron migration GO:0097476 4 1.000
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 1.000
forebrain neuron fate commitment GO:0021877 13 1.000
diencephalon development GO:0021536 63 1.000
neuron fate specification GO:0048665 30 1.000
Worm
cerebral cortex neuron differentiation GO:0021895 19 1.000
embryonic organ morphogenesis GO:0048562 276 1.000
telencephalon development GO:0021537 186 1.000
pituitary gland development GO:0021983 38 1.000
peripheral nervous system neuron axonogenesis GO:0048936 3 1.000
positive regulation of inner ear receptor cell differentiation GO:2000982 1 1.000
brain segmentation GO:0035284 3 1.000
Fly
cell proliferation in forebrain GO:0021846 30 1.000
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
central nervous system neuron differentiation GO:0021953 162 1.000
forebrain neuron differentiation GO:0021879 52 1.000
endodermal cell fate commitment GO:0001711 12 1.000
forebrain regionalization GO:0021871 25 1.000
olfactory lobe development GO:0021988 32 1.000
positive regulation of auditory receptor cell differentiation GO:0045609 1 1.000
neuron projection guidance GO:0097485 141 1.000
Human
gastrulation GO:0007369 116 1.000
spinal cord association neuron differentiation GO:0021527 14 1.000
neural tube closure GO:0001843 90 1.000
forebrain development GO:0030900 302 1.000
metencephalon development GO:0022037 89 1.000
pallium development GO:0021543 120 1.000
forebrain generation of neurons GO:0021872 63 1.000
dentate gyrus development GO:0021542 14 1.000
midbrain hindbrain boundary development GO:0030917 9 1.000
Zebrafish
visceral motor neuron differentiation GO:0021524 3 1.000
positive regulation of rhodopsin gene expression GO:0045872 2 1.000
Fly
cell proliferation in hindbrain GO:0021534 10 1.000
pyramidal neuron migration GO:0021852 1 1.000
appendage development GO:0048736 166 1.000
cell fate specification GO:0001708 72 1.000
neural tube development GO:0021915 160 1.000
Zebrafish
olfactory bulb development GO:0021772 30 1.000
spinal cord development GO:0021510 81 1.000
ventral spinal cord interneuron specification GO:0021521 11 1.000
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 1.000
appendage morphogenesis GO:0035107 149 1.000
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 1.000
nephric duct elongation GO:0035849 1 1.000
bmp signaling pathway GO:0030509 93 1.000
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 1.000
embryonic skeletal system development GO:0048706 120 1.000
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 1.000
cerebellar granule cell precursor proliferation GO:0021930 10 1.000
rostrocaudal neural tube patterning GO:0021903 12 1.000
Zebrafish
ventral spinal cord interneuron fate commitment GO:0060579 14 1.000
cerebral cortex development GO:0021987 86 1.000
hindbrain development GO:0030902 128 1.000
embryonic epithelial tube formation GO:0001838 130 1.000
hindbrain morphogenesis GO:0021575 46 1.000
regulation of heart morphogenesis GO:2000826 22 1.000
central nervous system neuron development GO:0021954 67 1.000
spinal cord motor neuron differentiation GO:0021522 35 1.000
somitogenesis GO:0001756 69 1.000
ventral spinal cord interneuron differentiation GO:0021514 16 1.000
neuron fate determination GO:0048664 9 1.000
retinal ganglion cell axon guidance GO:0031290 18 1.000
cerebral cortex tangential migration GO:0021800 7 1.000
embryonic viscerocranium morphogenesis GO:0048703 8 1.000
cell fate commitment GO:0045165 210 1.000
cerebral cortex gabaergic interneuron migration GO:0021853 6 1.000
cerebral cortex cell migration GO:0021795 44 1.000
limbic system development GO:0021761 72 1.000
granulocyte colony stimulating factor production GO:0071611 1 1.000
embryonic retina morphogenesis in camera type eye GO:0060059 7 1.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 1.000
cranial nerve development GO:0021545 41 1.000
forebrain cell migration GO:0021885 58 1.000
sensory organ morphogenesis GO:0090596 242 1.000
regulation of auditory receptor cell differentiation GO:0045607 4 1.000
hypothalamus development GO:0021854 16 1.000
cell differentiation in hindbrain GO:0021533 24 1.000
neural tube patterning GO:0021532 43 1.000
Zebrafish
cerebellar cortex formation GO:0021697 22 1.000
midbrain development GO:0030901 35 1.000
embryonic skeletal system morphogenesis GO:0048704 91 1.000
epithelial tube formation GO:0072175 130 1.000
neuroblast differentiation GO:0014016 2 1.000
endodermal cell fate specification GO:0001714 4 1.000
axon guidance GO:0007411 141 1.000
Human
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 1.000
cell fate determination GO:0001709 32 1.000
medial motor column neuron differentiation GO:0021526 2 1.000
morphogenesis of embryonic epithelium GO:0016331 159 1.000
metanephric dct cell differentiation GO:0072240 3 1.000
primary neural tube formation GO:0014020 95 1.000
inner ear receptor cell differentiation GO:0060113 61 1.000
oligodendrocyte development GO:0014003 20 1.000
thalamus development GO:0021794 11 1.000
spinal cord motor neuron cell fate specification GO:0021520 13 1.000
regulation of neuron projection development GO:0010975 169 1.000
embryonic heart tube formation GO:0003144 1 1.000
cerebellum development GO:0021549 77 1.000
cerebellar purkinje cell layer development GO:0021680 26 1.000
telencephalon cell migration GO:0022029 55 1.000
stem cell development GO:0048864 219 1.000
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 1.000
hemangioblast cell differentiation GO:0060217 1 1.000
regulation of neuron differentiation GO:0045664 281 1.000
Fly
heart formation GO:0060914 16 1.000
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 1.000
telencephalon regionalization GO:0021978 14 1.000
neural tube formation GO:0001841 108 1.000
spinal cord dorsal ventral patterning GO:0021513 23 1.000
metanephric nephron morphogenesis GO:0072273 19 1.000
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
trabecular meshwork development GO:0002930 2 1.000
neuron projection extension GO:1990138 64 1.000
regulation of bmp signaling pathway GO:0030510 60 1.000
limb morphogenesis GO:0035108 149 1.000
metanephros morphogenesis GO:0003338 24 1.000
cell differentiation in spinal cord GO:0021515 53 1.000
oligodendrocyte cell fate commitment GO:0021779 5 1.000
cardiac cell fate determination GO:0060913 2 1.000
mesoderm development GO:0007498 100 1.000
positive regulation of macrophage colony stimulating factor production GO:1901258 1 1.000
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 1.000
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 1.000
positive regulation of transcription by glucose GO:0046016 3 1.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 1.000
substrate independent telencephalic tangential interneuron migration GO:0021843 8 1.000
formation of primary germ layer GO:0001704 77 1.000
trophectodermal cell differentiation GO:0001829 21 1.000
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 1.000
retina development in camera type eye GO:0060041 119 1.000
Zebrafish Mouse
cerebral cortex radial glia guided migration GO:0021801 17 1.000
hair cell differentiation GO:0035315 40 1.000
cerebellar purkinje cell differentiation GO:0021702 13 1.000
s shaped body morphogenesis GO:0072050 6 1.000
cerebellar cortex development GO:0021695 48 1.000
substrate independent telencephalic tangential migration GO:0021826 8 1.000
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 1.000
ectoderm formation GO:0001705 3 1.000
cell proliferation in external granule layer GO:0021924 10 1.000
forebrain neuron development GO:0021884 30 1.000
forebrain anterior posterior pattern specification GO:0021797 5 1.000
autonomic nervous system development GO:0048483 43 1.000
somatotropin secreting cell differentiation GO:0060126 4 1.000
nerve development GO:0021675 67 1.000
astrocyte fate commitment GO:0060018 4 1.000
horizontal cell localization GO:0035852 1 1.000
forebrain morphogenesis GO:0048853 17 1.000
negative regulation of cell development GO:0010721 169 1.000
epithelial cell differentiation involved in kidney development GO:0035850 23 1.000
stem cell differentiation GO:0048863 268 1.000
rhombomere morphogenesis GO:0021593 2 1.000
gonad morphogenesis GO:0035262 1 1.000
central nervous system projection neuron axonogenesis GO:0021952 21 1.000
negative regulation of neuron differentiation GO:0045665 101 1.000
somatic motor neuron differentiation GO:0021523 6 1.000
photoreceptor cell fate commitment GO:0046552 2 1.000
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 1.000
auditory receptor cell fate specification GO:0042667 1 1.000
ureteric bud morphogenesis GO:0060675 62 1.000
segmentation GO:0035282 93 1.000
paraxial mesodermal cell differentiation GO:0048342 2 1.000
cell fate commitment involved in formation of primary germ layer GO:0060795 26 1.000
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 1.000
peripheral nervous system neuron development GO:0048935 9 1.000
tendon formation GO:0035992 4 1.000
cerebellum morphogenesis GO:0021587 42 1.000
hypothalamus cell differentiation GO:0021979 8 1.000
mesenchyme development GO:0060485 152 1.000
cell fate specification involved in pattern specification GO:0060573 11 1.000
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 1.000
cochlea morphogenesis GO:0090103 22 1.000
digestive tract morphogenesis GO:0048546 147 1.000
determination of heart left right asymmetry GO:0061371 48 1.000
hippocampus development GO:0021766 52 1.000
adenohypophysis development GO:0021984 14 1.000
tendon cell differentiation GO:0035990 4 1.000
brain morphogenesis GO:0048854 32 1.000
pancreatic pp cell fate commitment GO:0003329 2 1.000
epithelial cell maturation involved in prostate gland development GO:0060743 4 1.000
cardiac ventricle morphogenesis GO:0003208 50 1.000
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 1.000
interneuron migration from the subpallium to the cortex GO:0021830 7 1.000
tube formation GO:0035148 140 1.000
closure of optic fissure GO:0061386 2 1.000
positive regulation of keratinocyte proliferation GO:0010838 4 1.000
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 1.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 1.000
digestive system development GO:0055123 200 0.999
eye photoreceptor cell development GO:0042462 31 0.999
Fly
inner cell mass cell differentiation GO:0001826 7 0.999
limb development GO:0060173 166 0.999
regulation of timing of cell differentiation GO:0048505 11 0.999
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.999
neural crest cell development GO:0014032 48 0.999
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.999
endoderm formation GO:0001706 20 0.999
forebrain ventricular zone progenitor cell division GO:0021869 6 0.999
noradrenergic neuron differentiation GO:0003357 6 0.999
regulation of mast cell differentiation GO:0060375 3 0.999
pancreatic a cell fate commitment GO:0003326 2 0.999
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.999
nephron tubule morphogenesis GO:0072078 68 0.999
pancreatic pp cell differentiation GO:0003312 2 0.999
mesenchymal cell development GO:0014031 93 0.999
glial cell fate specification GO:0021780 5 0.999
cerebellar cortex morphogenesis GO:0021696 32 0.999
central nervous system neuron axonogenesis GO:0021955 28 0.999
outflow tract morphogenesis GO:0003151 53 0.999
somite rostral caudal axis specification GO:0032525 13 0.999
astrocyte differentiation GO:0048708 43 0.999
stem cell proliferation GO:0072089 117 0.999
rhombomere development GO:0021546 8 0.999
embryonic heart tube development GO:0035050 65 0.999
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.999
neural precursor cell proliferation GO:0061351 121 0.999
cardioblast proliferation GO:0003263 8 0.999
regulation of timing of neuron differentiation GO:0060164 5 0.999
axis elongation involved in somitogenesis GO:0090245 4 0.999
face morphogenesis GO:0060325 29 0.999
cardiac septum development GO:0003279 59 0.999
cerebral cortex gabaergic interneuron development GO:0021894 6 0.999
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.999
cardiac chamber morphogenesis GO:0003206 93 0.999
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.999
dorsal spinal cord development GO:0021516 20 0.999
trigeminal nerve development GO:0021559 10 0.999
paraxial mesodermal cell fate commitment GO:0048343 2 0.999
mesenchyme morphogenesis GO:0072132 32 0.999
heart morphogenesis GO:0003007 178 0.999
eye photoreceptor cell differentiation GO:0001754 41 0.999
positive regulation of bmp signaling pathway GO:0030513 23 0.999
skeletal system development GO:0001501 356 0.999
regulation of gastrulation GO:0010470 16 0.999
anterior head development GO:0097065 2 0.999
preganglionic parasympathetic nervous system development GO:0021783 17 0.999
positive regulation of glial cell differentiation GO:0045687 21 0.999
retina morphogenesis in camera type eye GO:0060042 45 0.999
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.999
regulation of organ formation GO:0003156 34 0.999
metanephric nephron tubule development GO:0072234 16 0.999
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.999
regulation of vascular wound healing GO:0061043 2 0.999
negative regulation of mesodermal cell fate specification GO:0042662 3 0.999
mesenchymal to epithelial transition GO:0060231 12 0.999
nephron morphogenesis GO:0072028 69 0.999
mesodermal cell differentiation GO:0048333 22 0.998
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.998
olfactory bulb interneuron development GO:0021891 7 0.998
renal vesicle induction GO:0072034 3 0.998
tongue development GO:0043586 18 0.998
regulation of somitogenesis GO:0014807 6 0.998
amacrine cell differentiation GO:0035881 5 0.998
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.998
retinal bipolar neuron differentiation GO:0060040 5 0.998
dendrite development GO:0016358 115 0.998
auditory receptor cell differentiation GO:0042491 37 0.998
digestive tract development GO:0048565 190 0.998
neurohypophysis development GO:0021985 2 0.998
stomach neuroendocrine cell differentiation GO:0061102 2 0.998
regulation of astrocyte differentiation GO:0048710 20 0.998
olfactory bulb interneuron differentiation GO:0021889 12 0.998
pattern specification involved in metanephros development GO:0072268 4 0.998
specification of loop of henle identity GO:0072086 4 0.998
tube closure GO:0060606 91 0.998
parasympathetic nervous system development GO:0048486 19 0.998
metanephric nephron tubule formation GO:0072289 4 0.998
negative regulation of osteoblast differentiation GO:0045668 30 0.998
neural crest cell differentiation GO:0014033 54 0.998
endocrine system development GO:0035270 98 0.998
embryonic heart tube morphogenesis GO:0003143 51 0.998
cell differentiation involved in kidney development GO:0061005 33 0.998
cardiac muscle cell myoblast differentiation GO:0060379 8 0.998
cardiac chamber development GO:0003205 108 0.998
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.998
embryonic eye morphogenesis GO:0048048 29 0.998
negative regulation of glial cell proliferation GO:0060253 4 0.998
specification of nephron tubule identity GO:0072081 5 0.998
lung induction GO:0060492 3 0.998
cardiac septum morphogenesis GO:0060411 46 0.998
transdifferentiation GO:0060290 1 0.998
cell proliferation involved in heart morphogenesis GO:0061323 15 0.998
neural crest cell migration GO:0001755 32 0.998
renal tubule development GO:0061326 87 0.998
regulation of neural retina development GO:0061074 3 0.997
respiratory system development GO:0060541 190 0.997
regulation of anterior head development GO:2000742 2 0.997
renal vesicle morphogenesis GO:0072077 15 0.997
epidermis development GO:0008544 187 0.997
cardiocyte differentiation GO:0035051 87 0.997
proximal distal pattern formation involved in nephron development GO:0072047 5 0.997
gland development GO:0048732 330 0.997
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.997
dopaminergic neuron differentiation GO:0071542 14 0.997
central nervous system segmentation GO:0035283 3 0.997
Fly
somite development GO:0061053 81 0.997
branching involved in ureteric bud morphogenesis GO:0001658 56 0.997
stem cell maintenance GO:0019827 130 0.997
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.997
renal vesicle development GO:0072087 17 0.997
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.997
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.997
lens morphogenesis in camera type eye GO:0002089 24 0.997
camera type eye development GO:0043010 266 0.997
Zebrafish Mouse
renal capsule specification GO:0072130 1 0.997
determination of left right symmetry GO:0007368 80 0.997
regulation of endodermal cell differentiation GO:1903224 2 0.997
muscle tissue morphogenesis GO:0060415 53 0.997
axonogenesis GO:0007409 274 0.997
Human
negative regulation of transcription by glucose GO:0045014 1 0.997
mechanoreceptor differentiation GO:0042490 67 0.997
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.997
developmental growth involved in morphogenesis GO:0060560 138 0.997
mesenchymal cell differentiation GO:0048762 107 0.997
sensory system development GO:0048880 3 0.997
gastrulation with mouth forming second GO:0001702 29 0.996
ear morphogenesis GO:0042471 118 0.996
cell fate commitment involved in pattern specification GO:0060581 14 0.996
mesoderm morphogenesis GO:0048332 64 0.996
neuroendocrine cell differentiation GO:0061101 7 0.996
enteroendocrine cell differentiation GO:0035883 16 0.996
metanephric capsule specification GO:0072267 1 0.996
skeletal system morphogenesis GO:0048705 203 0.996
positive regulation of neural precursor cell proliferation GO:2000179 42 0.996
axial mesodermal cell fate commitment GO:0048322 1 0.996
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.996
loop of henle development GO:0072070 10 0.996
regulation of mechanoreceptor differentiation GO:0045631 5 0.996
striated muscle tissue development GO:0014706 293 0.996
epithelial cell morphogenesis GO:0003382 41 0.996
metanephric loop of henle development GO:0072236 4 0.996
neural plate morphogenesis GO:0001839 9 0.996
glial cell differentiation GO:0010001 131 0.996
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.996
comma shaped body morphogenesis GO:0072049 5 0.996
vestibulocochlear nerve development GO:0021562 7 0.996
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.996
regulation of macrophage colony stimulating factor production GO:1901256 1 0.996
ventricular septum morphogenesis GO:0060412 27 0.995
macrophage colony stimulating factor production GO:0036301 1 0.995
negative regulation of synapse maturation GO:2000297 2 0.995
ascending aorta morphogenesis GO:0035910 3 0.995
rhombomere 2 development GO:0021568 2 0.995
metanephric tubule morphogenesis GO:0072173 9 0.995
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.995
embryonic appendage morphogenesis GO:0035113 126 0.995
glial cell fate commitment GO:0021781 14 0.995
negative regulation of dna binding GO:0043392 20 0.995
cardiac muscle tissue development GO:0048738 130 0.995
primitive streak formation GO:0090009 10 0.995
ear development GO:0043583 200 0.995
epithalamus development GO:0021538 2 0.995
subpallium neuron fate commitment GO:0060163 2 0.995
ventral spinal cord development GO:0021517 48 0.995
metanephric tubule development GO:0072170 18 0.995
positive regulation of anterior head development GO:2000744 2 0.995
cardiac muscle tissue morphogenesis GO:0055008 44 0.995
negative regulation of pancreatic a cell differentiation GO:2000227 1 0.995
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.994
nose development GO:0043584 12 0.994
pattern specification involved in kidney development GO:0061004 8 0.994
somatic stem cell maintenance GO:0035019 47 0.994
inner ear morphogenesis GO:0042472 101 0.994
cerebellar granule cell differentiation GO:0021707 9 0.994
neuroblast proliferation GO:0007405 49 0.994
endocardial cushion morphogenesis GO:0003203 18 0.994
cranial suture morphogenesis GO:0060363 8 0.994
spemann organizer formation GO:0060061 2 0.994
head morphogenesis GO:0060323 34 0.994
locus ceruleus development GO:0021703 1 0.994
cardiac muscle cell differentiation GO:0055007 69 0.994
regulation of cardioblast proliferation GO:0003264 9 0.994
dorsal ventral neural tube patterning GO:0021904 28 0.994
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.994
regulation of glial cell differentiation GO:0045685 41 0.993
positive regulation of stem cell proliferation GO:2000648 59 0.993
cardiac cell fate commitment GO:0060911 10 0.993
forebrain radial glial cell differentiation GO:0021861 4 0.993
pancreas development GO:0031016 57 0.993
regulation of stem cell proliferation GO:0072091 78 0.993
metanephric s shaped body morphogenesis GO:0072284 2 0.993
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.992
blastocyst formation GO:0001825 33 0.992
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.992
hindlimb morphogenesis GO:0035137 42 0.992
pharyngeal system development GO:0060037 17 0.992
negative regulation of glial cell differentiation GO:0045686 21 0.992
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.992
heart field specification GO:0003128 6 0.992
globus pallidus development GO:0021759 2 0.992
camera type eye photoreceptor cell differentiation GO:0060219 15 0.992
trophoblast giant cell differentiation GO:0060707 15 0.991
hypophysis morphogenesis GO:0048850 3 0.991
regulation of stem cell maintenance GO:2000036 17 0.991
negative regulation of astrocyte differentiation GO:0048712 10 0.991
photoreceptor cell differentiation GO:0046530 52 0.991
cardiac right ventricle formation GO:0003219 3 0.991
epithelial tube morphogenesis GO:0060562 303 0.991
regulation of inner ear receptor cell differentiation GO:2000980 5 0.991
regulation of cell division GO:0051302 76 0.991
metanephric renal vesicle morphogenesis GO:0072283 12 0.991
negative regulation of stomach neuroendocrine cell differentiation GO:0061106 1 0.990
sclerotome development GO:0061056 4 0.990
renal system development GO:0072001 225 0.990
oviduct epithelium development GO:0035846 1 0.990
neural retina development GO:0003407 41 0.990
innervation GO:0060384 22 0.990
regulation of chondrocyte differentiation GO:0032330 33 0.990
peripheral nervous system neuron differentiation GO:0048934 9 0.990
regulation of neuron apoptotic process GO:0043523 122 0.990
metanephros development GO:0001656 79 0.990
diencephalon morphogenesis GO:0048852 6 0.990
chondrocyte differentiation GO:0002062 72 0.990
epidermal cell fate specification GO:0009957 1 0.989
fourth ventricle development GO:0021592 2 0.989
regulation of muscle tissue development GO:1901861 97 0.989
carbon catabolite repression of transcription GO:0045013 1 0.989
myelination in peripheral nervous system GO:0022011 19 0.989
cell differentiation involved in embryonic placenta development GO:0060706 26 0.989
regulation of asymmetric cell division GO:0009786 4 0.989
mesonephric tubule morphogenesis GO:0072171 63 0.989
tongue morphogenesis GO:0043587 8 0.989
regulation of endodermal cell fate specification GO:0042663 2 0.989
inner cell mass cell fate commitment GO:0001827 2 0.989
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.988
endoderm development GO:0007492 45 0.988
nephron epithelium morphogenesis GO:0072088 68 0.988
cerebral cortex regionalization GO:0021796 8 0.988
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.988
cardiac chamber formation GO:0003207 10 0.988
embryonic forelimb morphogenesis GO:0035115 32 0.988
midbrain hindbrain boundary maturation GO:0021732 1 0.988
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.987
motor neuron axon guidance GO:0008045 26 0.987
primary prostatic bud elongation GO:0060516 2 0.987
regulation of secondary heart field cardioblast proliferation GO:0003266 9 0.987
negative regulation of cell fate specification GO:0009996 4 0.987
ureteric bud development GO:0001657 94 0.987
nephron development GO:0072006 109 0.986
cardiac neural crest cell development involved in heart development GO:0061308 7 0.986
cerebellum formation GO:0021588 1 0.986
cervix development GO:0060067 2 0.986
mesodermal cell fate commitment GO:0001710 17 0.986
positive regulation of gastrulation GO:2000543 6 0.986
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.986
maintenance of apical basal cell polarity GO:0035090 3 0.986
epithelial to mesenchymal transition GO:0001837 47 0.986
cell migration in hindbrain GO:0021535 16 0.986
cardiac atrium morphogenesis GO:0003209 23 0.986
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.986
skeletal muscle cell differentiation GO:0035914 66 0.986
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.985
stem cell fate specification GO:0048866 3 0.985
histone acetylation GO:0016573 41 0.985
ectodermal placode formation GO:0060788 16 0.985
floor plate morphogenesis GO:0033505 3 0.985
regulation of gliogenesis GO:0014013 50 0.985
chemotaxis GO:0006935 247 0.985
Human
positive regulation of nervous system development GO:0051962 221 0.985
Fly
cardiac neural crest cell differentiation involved in heart development GO:0061307 8 0.985
ureter morphogenesis GO:0072197 4 0.985
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.985
nephron tubule development GO:0072080 84 0.985
atrioventricular valve morphogenesis GO:0003181 13 0.985
angiogenesis GO:0001525 201 0.985
erythrocyte maturation GO:0043249 6 0.985
gabaergic neuron differentiation GO:0097154 11 0.984
deltoid tuberosity development GO:0035993 3 0.984
regulation of interleukin 1 alpha production GO:0032650 4 0.984
proprioception GO:0019230 4 0.984
endocardial cell differentiation GO:0060956 4 0.984
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.984
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.983
mesonephros development GO:0001823 97 0.983
granulosa cell differentiation GO:0060014 1 0.983
regulation of interleukin 1 production GO:0032652 26 0.983
positive regulation of cell death GO:0010942 224 0.983
negative regulation of mesenchymal cell apoptotic process GO:2001054 11 0.982
endocrine pancreas development GO:0031018 29 0.982
mitochondrion distribution GO:0048311 4 0.982
inner ear receptor cell fate commitment GO:0060120 6 0.982
mesenchymal cell proliferation GO:0010463 44 0.982
endocardial cushion development GO:0003197 26 0.981
placenta development GO:0001890 140 0.981
developmental cell growth GO:0048588 84 0.980
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.980
cardiac ventricle development GO:0003231 83 0.980
formation of radial glial scaffolds GO:0021943 4 0.980
spinal cord patterning GO:0021511 25 0.980
rhombomere 3 morphogenesis GO:0021658 2 0.980
regulation of neuroblast proliferation GO:1902692 27 0.980
neuroepithelial cell differentiation GO:0060563 37 0.979
cartilage morphogenesis GO:0060536 11 0.979

Otx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org