Mus musculus

206 known processes

Phox2b

paired-like homeobox 2b

(Aliases: Pmx2b,NBPhox,Dilp1)

Phox2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral line nerve development GO:0048892 1 0.999
spinal cord development GO:0021510 81 0.986
Mouse
neural crest cell migration GO:0001755 32 0.979
hindbrain morphogenesis GO:0021575 46 0.973
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.973
nerve development GO:0021675 67 0.969
hindbrain development GO:0030902 128 0.965
neuron projection guidance GO:0097485 141 0.965
Mouse Worm
central nervous system neuron differentiation GO:0021953 162 0.961
dorsal spinal cord development GO:0021516 20 0.951
Mouse
cell differentiation in hindbrain GO:0021533 24 0.948
metencephalon development GO:0022037 89 0.946
Mouse
olfactory bulb interneuron differentiation GO:0021889 12 0.939
forebrain neuron differentiation GO:0021879 52 0.927
axon guidance GO:0007411 141 0.926
Mouse Worm
autonomic nervous system development GO:0048483 43 0.922
cranial nerve development GO:0021545 41 0.919
neural crest cell development GO:0014032 48 0.914
noradrenergic neuron differentiation GO:0003357 6 0.908
olfactory lobe development GO:0021988 32 0.906
sympathetic nervous system development GO:0048485 22 0.906
cerebellar cortex formation GO:0021697 22 0.902
ventral spinal cord development GO:0021517 48 0.890
Mouse
subpallium neuron fate commitment GO:0060163 2 0.887
ventral spinal cord interneuron fate commitment GO:0060579 14 0.887
oligodendrocyte differentiation GO:0048709 53 0.877
pituitary gland development GO:0021983 38 0.857
olfactory bulb development GO:0021772 30 0.853
morphogenesis of a branching epithelium GO:0061138 193 0.853
cell differentiation in spinal cord GO:0021515 53 0.850
Mouse
enteric nervous system development GO:0048484 11 0.847
ureteric bud morphogenesis GO:0060675 62 0.847
cerebral cortex cell migration GO:0021795 44 0.841
pallium development GO:0021543 120 0.837
sensory system development GO:0048880 3 0.828
peripheral nervous system development GO:0007422 53 0.828
kidney development GO:0001822 213 0.827
cerebral cortex development GO:0021987 86 0.825
oligodendrocyte cell fate commitment GO:0021779 5 0.824
glial cell differentiation GO:0010001 131 0.819
kidney epithelium development GO:0072073 121 0.815
telencephalon cell migration GO:0022029 55 0.807
spinal cord motor neuron differentiation GO:0021522 35 0.806
Mouse
skeletal system development GO:0001501 356 0.805
Mouse
central nervous system morphogenesis GO:0021551 2 0.800
negative regulation of neuron death GO:1901215 98 0.799
cerebellum development GO:0021549 77 0.794
schwann cell development GO:0014044 22 0.780
positive regulation of neuron differentiation GO:0045666 141 0.777
nephron tubule morphogenesis GO:0072078 68 0.771
forebrain generation of neurons GO:0021872 63 0.770
forebrain cell migration GO:0021885 58 0.764
embryonic organ morphogenesis GO:0048562 276 0.763
Mouse
glial cell development GO:0021782 54 0.760
rhombomere 5 development GO:0021571 4 0.759
parasympathetic nervous system development GO:0048486 19 0.756
stem cell development GO:0048864 219 0.746
skeletal muscle cell differentiation GO:0035914 66 0.746
regulation of cellular amine metabolic process GO:0033238 20 0.744
gliogenesis GO:0042063 141 0.738
astrocyte fate commitment GO:0060018 4 0.737
medulla oblongata development GO:0021550 3 0.727
ameboidal type cell migration GO:0001667 128 0.724
neural crest cell differentiation GO:0014033 54 0.723
rhombomere development GO:0021546 8 0.721
ventral spinal cord interneuron differentiation GO:0021514 16 0.714
limbic system development GO:0021761 72 0.710
cellular amine metabolic process GO:0044106 44 0.707
ear development GO:0043583 200 0.695
sensory organ morphogenesis GO:0090596 242 0.693
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.689
spinal cord association neuron differentiation GO:0021527 14 0.689
regulation of cellular amino acid metabolic process GO:0006521 5 0.679
rhombomere 3 morphogenesis GO:0021658 2 0.676
female gonad development GO:0008585 71 0.676
regulation of cellular ketone metabolic process GO:0010565 66 0.673
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.672
trigeminal nerve development GO:0021559 10 0.669
Mouse
mesenchymal cell differentiation GO:0048762 107 0.669
brain segmentation GO:0035284 3 0.666
telencephalon development GO:0021537 186 0.665
striated muscle tissue development GO:0014706 293 0.662
cell fate specification involved in pattern specification GO:0060573 11 0.653
ventral spinal cord interneuron specification GO:0021521 11 0.647
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.642
digestive system development GO:0055123 200 0.639
glial cell fate specification GO:0021780 5 0.639
cognition GO:0050890 149 0.635
mesonephric tubule morphogenesis GO:0072171 63 0.633
motor neuron axon guidance GO:0008045 26 0.627
nephron morphogenesis GO:0072028 69 0.627
cerebellum morphogenesis GO:0021587 42 0.618
cellular ketone metabolic process GO:0042180 84 0.609
positive regulation of cell development GO:0010720 237 0.606
motor neuron migration GO:0097475 4 0.604
forebrain development GO:0030900 302 0.603
central nervous system segmentation GO:0035283 3 0.595
cell fate specification GO:0001708 72 0.594
mesenchymal cell development GO:0014031 93 0.593
hypothalamus development GO:0021854 16 0.591
spinal cord patterning GO:0021511 25 0.590
cardiac muscle tissue development GO:0048738 130 0.589
chemotaxis GO:0006935 247 0.585
Mouse Worm
regulation of organ morphogenesis GO:2000027 144 0.580
negative regulation of neuron differentiation GO:0045665 101 0.572
rhombomere morphogenesis GO:0021593 2 0.572
muscle tissue morphogenesis GO:0060415 53 0.567
negative regulation of cell proliferation GO:0008285 296 0.567
regulation of neuron differentiation GO:0045664 281 0.565
cellular amino acid metabolic process GO:0006520 103 0.565
embryonic skeletal system development GO:0048706 120 0.564
Mouse
cell proliferation in external granule layer GO:0021924 10 0.558
gland development GO:0048732 330 0.551
lateral motor column neuron migration GO:0097477 3 0.550
skeletal system morphogenesis GO:0048705 203 0.546
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.543
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.542
cell fate commitment GO:0045165 210 0.538
development of primary female sexual characteristics GO:0046545 73 0.535
renal system development GO:0072001 225 0.535
pons development GO:0021548 13 0.534
Mouse
limb development GO:0060173 166 0.534
Mouse
positive regulation of nervous system development GO:0051962 221 0.532
diencephalon development GO:0021536 63 0.530
regulation of neuron projection development GO:0010975 169 0.527
Worm
heart trabecula morphogenesis GO:0061384 26 0.523
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.523
positive regulation of cellular amine metabolic process GO:0033240 5 0.523
mesenchyme development GO:0060485 152 0.521
neuron apoptotic process GO:0051402 142 0.521
ureteric bud development GO:0001657 94 0.520
response to peptide hormone GO:0043434 127 0.518
negative regulation of nervous system development GO:0051961 156 0.517
glial cell fate commitment GO:0021781 14 0.513
cerebellar granule cell precursor proliferation GO:0021930 10 0.511
bmp signaling pathway GO:0030509 93 0.509
cell proliferation in hindbrain GO:0021534 10 0.504
midbrain development GO:0030901 35 0.496
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.487
Mouse
stem cell differentiation GO:0048863 268 0.483
lateral line system development GO:0048925 1 0.473
spinal cord motor neuron migration GO:0097476 4 0.472
appendage morphogenesis GO:0035107 149 0.471
Mouse
cerebellar cortex morphogenesis GO:0021696 32 0.471
regulation of system process GO:0044057 200 0.469
positive regulation of protein modification process GO:0031401 299 0.458
axonogenesis GO:0007409 274 0.448
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.444
urogenital system development GO:0001655 261 0.442
rhombomere 3 development GO:0021569 4 0.440
hippocampus development GO:0021766 52 0.439
regulation of morphogenesis of a branching structure GO:0060688 53 0.438
cardiac muscle cell proliferation GO:0060038 31 0.437
ensheathment of neurons GO:0007272 76 0.436
horizontal cell localization GO:0035852 1 0.434
central nervous system neuron development GO:0021954 67 0.426
dopaminergic neuron differentiation GO:0071542 14 0.424
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.418
regulation of axon extension GO:0030516 43 0.415
Worm
camera type eye development GO:0043010 266 0.415
metanephros development GO:0001656 79 0.414
respiratory system process GO:0003016 25 0.413
oligodendrocyte cell fate specification GO:0021778 5 0.411
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.407
spinal cord dorsal ventral patterning GO:0021513 23 0.405
cerebellar purkinje cell layer development GO:0021680 26 0.405
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.404
cardiac muscle tissue morphogenesis GO:0055008 44 0.402
negative regulation of secretion GO:0051048 61 0.398
adenohypophysis development GO:0021984 14 0.398
brain morphogenesis GO:0048854 32 0.398
axon ensheathment GO:0008366 76 0.395
regulation of respiratory system process GO:0044065 13 0.394
auditory receptor cell fate determination GO:0042668 3 0.393
forebrain morphogenesis GO:0048853 17 0.388
circulatory system process GO:0003013 197 0.388
multicellular organismal signaling GO:0035637 91 0.387
regulation of glial cell differentiation GO:0045685 41 0.384
neuron fate specification GO:0048665 30 0.379
male sex differentiation GO:0046661 109 0.378
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.373
neuromuscular process GO:0050905 99 0.373
forebrain regionalization GO:0021871 25 0.372
regulation of apoptotic signaling pathway GO:2001233 197 0.371
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.367
amine metabolic process GO:0009308 45 0.367
neuron migration GO:0001764 122 0.362
sympathetic ganglion development GO:0061549 9 0.361
synaptic transmission GO:0007268 329 0.361
regulation of neuron death GO:1901214 134 0.359
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.358
cardiac ventricle morphogenesis GO:0003208 50 0.353
positive regulation of angiogenesis GO:0045766 46 0.350
hemangioblast cell differentiation GO:0060217 1 0.345
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.345
striated muscle cell proliferation GO:0014855 39 0.340
cytokine production GO:0001816 319 0.339
peptidyl tyrosine modification GO:0018212 145 0.338
endocrine system development GO:0035270 98 0.337
epithelial tube morphogenesis GO:0060562 303 0.336
mesodermal cell fate specification GO:0007501 11 0.333
cerebral cortex radially oriented cell migration GO:0021799 31 0.329
cerebellar cortex development GO:0021695 48 0.326
regulation of cardiac muscle cell proliferation GO:0060043 23 0.326
telencephalon regionalization GO:0021978 14 0.323
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.321
transmission of nerve impulse GO:0019226 76 0.318
schwann cell differentiation GO:0014037 26 0.316
dentate gyrus development GO:0021542 14 0.311
placenta development GO:0001890 140 0.310
nephron epithelium development GO:0072009 92 0.309
embryonic epithelial tube formation GO:0001838 130 0.305
regulation of kidney development GO:0090183 40 0.304
branching involved in ureteric bud morphogenesis GO:0001658 56 0.303
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.303
negative regulation of epithelial cell proliferation GO:0050680 64 0.301
peptidyl amino acid modification GO:0018193 336 0.296
renal system process GO:0003014 48 0.295
negative regulation of ossification GO:0030279 49 0.293
ear morphogenesis GO:0042471 118 0.293
Mouse
regulation of transferase activity GO:0051338 263 0.290
regionalization GO:0003002 337 0.290
dendrite development GO:0016358 115 0.288
response to acid chemical GO:0001101 111 0.288
eye photoreceptor cell differentiation GO:0001754 41 0.287
detection of external stimulus GO:0009581 61 0.286
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.281
Mouse
cell maturation GO:0048469 127 0.280
cardiac cell fate specification GO:0060912 2 0.278
trabecular meshwork development GO:0002930 2 0.277
muscle cell proliferation GO:0033002 52 0.277
noradrenergic neuron development GO:0003358 3 0.276
odontogenesis GO:0042476 78 0.276
regulation of wnt signaling pathway GO:0030111 123 0.276
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.274
myelination GO:0042552 74 0.271
muscle cell differentiation GO:0042692 261 0.271
regulation of heart growth GO:0060420 31 0.271
cerebellar purkinje cell differentiation GO:0021702 13 0.270
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.270
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.268
hindbrain tangential cell migration GO:0021934 2 0.268
positive regulation of protein phosphorylation GO:0001934 242 0.267
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.266
nephron tubule development GO:0072080 84 0.261
segmentation GO:0035282 93 0.258
negative regulation of immune system process GO:0002683 209 0.257
regulation of gliogenesis GO:0014013 50 0.257
digestive tract development GO:0048565 190 0.256
negative regulation of apoptotic signaling pathway GO:2001234 104 0.255
negative regulation of neuron apoptotic process GO:0043524 92 0.254
regulation of interleukin 6 production GO:0032675 55 0.250
metanephric nephron morphogenesis GO:0072273 19 0.250
preganglionic parasympathetic nervous system development GO:0021783 17 0.248
Mouse
mechanoreceptor differentiation GO:0042490 67 0.247
peptidyl tyrosine phosphorylation GO:0018108 143 0.245
learning or memory GO:0007611 148 0.244
inner ear morphogenesis GO:0042472 101 0.242
Mouse
kidney morphogenesis GO:0060993 83 0.241
metanephric nephron development GO:0072210 34 0.240
innervation GO:0060384 22 0.239
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.237
positive regulation of kidney development GO:0090184 28 0.235
morphogenesis of embryonic epithelium GO:0016331 159 0.233
response to peptide GO:1901652 136 0.233
cardiac muscle cell differentiation GO:0055007 69 0.233
stem cell maintenance GO:0019827 130 0.233
positive regulation of cardiac muscle tissue development GO:0055025 19 0.232
facial nerve morphogenesis GO:0021610 11 0.232
cardiac chamber development GO:0003205 108 0.231
mesonephros development GO:0001823 97 0.229
cellular response to hormone stimulus GO:0032870 150 0.222
connective tissue development GO:0061448 179 0.222
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.220
lymphocyte differentiation GO:0030098 242 0.220
stem cell proliferation GO:0072089 117 0.219
Mouse
regulation of mast cell differentiation GO:0060375 3 0.218
hematopoietic progenitor cell differentiation GO:0002244 143 0.218
epithelial tube formation GO:0072175 130 0.218
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.218
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.213
muscle tissue development GO:0060537 308 0.213
cellular response to acid chemical GO:0071229 68 0.212
carbohydrate transport GO:0008643 62 0.212
determination of heart left right asymmetry GO:0061371 48 0.212
establishment of neuroblast polarity GO:0045200 1 0.211
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.210
negative regulation of synapse maturation GO:2000297 2 0.208
mitral valve morphogenesis GO:0003183 4 0.208
regulation of kinase activity GO:0043549 249 0.204
cranial nerve morphogenesis GO:0021602 26 0.203
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.202
cell type specific apoptotic process GO:0097285 268 0.202
rhombomere 2 development GO:0021568 2 0.198
erk1 and erk2 cascade GO:0070371 77 0.196
blood vessel morphogenesis GO:0048514 285 0.196
Mouse
neuron death GO:0070997 154 0.195
auditory receptor cell fate specification GO:0042667 1 0.194
organic hydroxy compound metabolic process GO:1901615 203 0.194
nephron development GO:0072006 109 0.194
cell fate commitment involved in pattern specification GO:0060581 14 0.193
neural tube development GO:0021915 160 0.193
positive regulation of heart growth GO:0060421 18 0.191
renal tubule development GO:0061326 87 0.191
mesenchymal to epithelial transition GO:0060231 12 0.189
cell migration involved in gastrulation GO:0042074 13 0.189
respiratory gaseous exchange GO:0007585 43 0.185
positive regulation of macrophage colony stimulating factor production GO:1901258 1 0.185
regulation of transcription involved in cell fate commitment GO:0060850 15 0.185
negative regulation of protein metabolic process GO:0051248 282 0.184
visceral motor neuron differentiation GO:0021524 3 0.182
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.182
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.181
embryonic heart tube formation GO:0003144 1 0.179
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.179
regulation of muscle tissue development GO:1901861 97 0.179
wound healing GO:0042060 157 0.178
tissue remodeling GO:0048771 102 0.178
ventricular cardiac muscle tissue development GO:0003229 38 0.177
germ cell development GO:0007281 185 0.177
ectoderm formation GO:0001705 3 0.176
pancreatic pp cell fate commitment GO:0003329 2 0.175
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.175
immature t cell proliferation GO:0033079 8 0.173
positive regulation of protein kinase activity GO:0045860 144 0.172
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.171
somite development GO:0061053 81 0.171
regeneration GO:0031099 38 0.170
adult behavior GO:0030534 135 0.170
respiratory system development GO:0060541 190 0.169
forebrain neuron development GO:0021884 30 0.168
regulation of bmp signaling pathway GO:0030510 60 0.167
cellular response to insulin stimulus GO:0032869 78 0.166
epithelial cell morphogenesis GO:0003382 41 0.166
positive regulation of transferase activity GO:0051347 167 0.166
transmembrane transport GO:0055085 412 0.166
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.165
blood circulation GO:0008015 195 0.164
synapse organization GO:0050808 125 0.164
regulation of cell motility GO:2000145 236 0.163
cardiocyte differentiation GO:0035051 87 0.162
regulation of epithelial cell proliferation GO:0050678 141 0.162
regulation of macrophage colony stimulating factor production GO:1901256 1 0.162
cellular response to growth factor stimulus GO:0071363 197 0.162
signal transduction in absence of ligand GO:0038034 55 0.160
morphogenesis of a branching structure GO:0001763 203 0.159
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.156
cardiac muscle cell myoblast differentiation GO:0060379 8 0.155
paramesonephric duct development GO:0061205 3 0.155
axon target recognition GO:0007412 4 0.155
positive regulation of gliogenesis GO:0014015 27 0.153
regulation of respiratory gaseous exchange GO:0043576 18 0.150
positive regulation of mesonephros development GO:0061213 20 0.149
photoreceptor cell differentiation GO:0046530 52 0.149
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.148
astrocyte differentiation GO:0048708 43 0.147
mitochondrion organization GO:0007005 134 0.147
embryonic eye morphogenesis GO:0048048 29 0.145
appendage development GO:0048736 166 0.145
Mouse
hexose transport GO:0008645 56 0.144
regulation of secretion GO:0051046 274 0.143
gonad development GO:0008406 141 0.141
cardiac muscle tissue growth GO:0055017 37 0.141
regulation of interleukin 1 alpha production GO:0032650 4 0.140
molting cycle GO:0042303 90 0.139
negative regulation of mesodermal cell fate specification GO:0042662 3 0.139
learning GO:0007612 98 0.139
hair cycle GO:0042633 90 0.138
regulation of vasculature development GO:1901342 88 0.137
somatotropin secreting cell differentiation GO:0060126 4 0.136
small gtpase mediated signal transduction GO:0007264 97 0.136
visceral serous pericardium development GO:0061032 2 0.135
developmental growth involved in morphogenesis GO:0060560 138 0.135
Worm
positive regulation of epithelial cell proliferation GO:0050679 68 0.133
female sex differentiation GO:0046660 84 0.133
regulation of positive chemotaxis GO:0050926 7 0.133
embryonic placenta development GO:0001892 98 0.133
mammary gland lobule development GO:0061377 22 0.133
regulation of cell activation GO:0050865 289 0.132
mesodermal cell fate commitment GO:0001710 17 0.131
stem cell fate specification GO:0048866 3 0.131
jak stat cascade GO:0007259 42 0.130
positive regulation of programmed cell death GO:0043068 218 0.129
heart morphogenesis GO:0003007 178 0.128
pyramidal neuron migration GO:0021852 1 0.128
pharynx development GO:0060465 1 0.128
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.128
specification of organ position GO:0010159 3 0.127
regulation of cell size GO:0008361 72 0.126
Worm
apoptotic signaling pathway GO:0097190 306 0.126
carbohydrate homeostasis GO:0033500 128 0.126
positive regulation of neural precursor cell proliferation GO:2000179 42 0.126
positive regulation of fibroblast proliferation GO:0048146 20 0.126
medial motor column neuron differentiation GO:0021526 2 0.126
regulation of extent of cell growth GO:0061387 52 0.124
Worm
oviduct development GO:0060066 3 0.123
organic acid transport GO:0015849 101 0.123
spermatogenesis GO:0007283 284 0.122
neuroblast fate commitment GO:0014017 1 0.122
leukocyte differentiation GO:0002521 342 0.122
regulation of jak stat cascade GO:0046425 34 0.121
t cell activation GO:0042110 289 0.121
regulation of anterior head development GO:2000742 2 0.120
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.120
neuronal action potential GO:0019228 54 0.119
regulation of t cell differentiation GO:0045580 83 0.119
regulation of auditory receptor cell differentiation GO:0045607 4 0.117
positive regulation of protein tyrosine kinase activity GO:0061098 10 0.117
negative regulation of immature t cell proliferation GO:0033087 3 0.116
pancreatic a cell fate commitment GO:0003326 2 0.115
cardiac ventricle development GO:0003231 83 0.115
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.114
trabecula morphogenesis GO:0061383 40 0.114
ventricular septum development GO:0003281 42 0.114
mesoderm development GO:0007498 100 0.114
taste bud development GO:0061193 2 0.114
cation transport GO:0006812 399 0.113
positive regulation of metanephros development GO:0072216 9 0.113
positive regulation of neuron projection regeneration GO:0070572 2 0.113
cerebral cortex tangential migration GO:0021800 7 0.113
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.113
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.112
thalamus development GO:0021794 11 0.112
extracellular matrix organization GO:0030198 147 0.111
endothelium development GO:0003158 45 0.111
cell growth GO:0016049 130 0.110
Worm
regulation of granulocyte colony stimulating factor production GO:0071655 1 0.110
inner ear receptor cell differentiation GO:0060113 61 0.110
cellular response to retinoic acid GO:0071300 25 0.109
oxidation reduction process GO:0055114 342 0.109
locomotory behavior GO:0007626 195 0.109
male gonad development GO:0008584 88 0.109
subpallium development GO:0021544 20 0.108
erbb signaling pathway GO:0038127 32 0.108
specification of organ identity GO:0010092 30 0.108
postganglionic parasympathetic nervous system development GO:0021784 2 0.108
neural retina development GO:0003407 41 0.108
carbohydrate metabolic process GO:0005975 230 0.108
endocardial cell differentiation GO:0060956 4 0.107
neuron recognition GO:0008038 25 0.107
aortic valve morphogenesis GO:0003180 4 0.107
spinal cord motor neuron cell fate specification GO:0021520 13 0.106
developmental induction GO:0031128 34 0.106
regulation of protein tyrosine kinase activity GO:0061097 17 0.106
olfactory learning GO:0008355 2 0.106
somatic motor neuron differentiation GO:0021523 6 0.106
Mouse
positive regulation of cytokine production GO:0001819 174 0.105
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.105
myeloid cell homeostasis GO:0002262 114 0.105
central nervous system neuron axonogenesis GO:0021955 28 0.104
cardiac cell fate determination GO:0060913 2 0.104
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.103
positive regulation of striated muscle tissue development GO:0045844 31 0.103
regulation of cardiac cell fate specification GO:2000043 1 0.103
cranial nerve structural organization GO:0021604 13 0.102
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.102
transcription from rna polymerase iii promoter GO:0006383 3 0.101
t cell differentiation in thymus GO:0033077 77 0.101
oculomotor nerve morphogenesis GO:0021622 2 0.101
Mouse
myelination in peripheral nervous system GO:0022011 19 0.100
negative regulation of muscle cell apoptotic process GO:0010656 9 0.100
monosaccharide transport GO:0015749 58 0.100
regulation of systemic arterial blood pressure GO:0003073 61 0.100
monocarboxylic acid metabolic process GO:0032787 191 0.099
cellular response to lipid GO:0071396 145 0.099
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.099
negative regulation of t cell activation GO:0050868 65 0.098
granulocyte colony stimulating factor production GO:0071611 1 0.098
negative regulation of leukocyte differentiation GO:1902106 51 0.098
regulation of ion homeostasis GO:2000021 64 0.098
negative regulation of protein modification process GO:0031400 163 0.098
anterior head development GO:0097065 2 0.098
small molecule biosynthetic process GO:0044283 132 0.097
glucose transport GO:0015758 56 0.096
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.095
cellular response to organonitrogen compound GO:0071417 145 0.095
positive regulation of secretion GO:0051047 130 0.095
mucosal associated lymphoid tissue development GO:0048537 12 0.095
regulation of neuron apoptotic process GO:0043523 122 0.095
regulation of stat protein import into nucleus GO:2000364 2 0.095
ion transmembrane transport GO:0034220 361 0.095
mesenchyme morphogenesis GO:0072132 32 0.094
positive regulation of map kinase activity GO:0043406 84 0.094
positive regulation of muscle tissue development GO:1901863 32 0.094
regulation of cell growth GO:0001558 91 0.093
Worm
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.093
ganglion development GO:0061548 13 0.092
positive regulation of striated muscle cell differentiation GO:0051155 35 0.092
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.092
positive regulation of neuron maturation GO:0014042 2 0.092
neurotransmitter transport GO:0006836 76 0.092
peripheral nervous system neuron development GO:0048935 9 0.092
neuroblast proliferation GO:0007405 49 0.090

Phox2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.292
cancer DOID:162 0 0.104
organ system cancer DOID:0050686 0 0.104