IMP

Process View

Mus musculus

3 genes annotated in mouse

noradrenergic neuron development

The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "noradrenergic neuron development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "noradrenergic neuron development" (in gray)

Name	Description	Probability	Func Analog Organism
Msx1	homeobox, msh-like 1	0.999
Shh	sonic hedgehog	0.998
Eya1	eyes absent 1 homolog (Drosophila)	0.995
Sox9	SRY-box containing gene 9	0.994
Gli3	GLI-Kruppel family member GLI3	0.992
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.988
Isl1	ISL1 transcription factor, LIM/homeodomain	0.986
Tcfap2a	transcription factor AP-2, alpha	0.985
Hand2	heart and neural crest derivatives expressed transcript 2	0.972
Foxc1	forkhead box C1	0.962
Pax3	paired box gene 3	0.960
Otx2	orthodenticle homolog 2 (Drosophila)	0.955
Tbx1	T-box 1	0.947
Chrd	chordin	0.940
Dlx5	distal-less homeobox 5	0.931
Bmp4	bone morphogenetic protein 4	0.927
Prrx2	paired related homeobox 2	0.921	Mouse
Foxc2	forkhead box C2	0.910
Fgf8	fibroblast growth factor 8	0.900
Fgfr2	fibroblast growth factor receptor 2	0.888
Bmp7	bone morphogenetic protein 7	0.882
Hand1	heart and neural crest derivatives expressed transcript 1	0.854
Ednra	endothelin receptor type A	0.849
Pitx2	paired-like homeodomain transcription factor 2	0.826
Tgfb2	transforming growth factor, beta 2	0.792
Gbx2	gastrulation brain homeobox 2	0.781
Smo	smoothened homolog (Drosophila)	0.758
Ret	ret proto-oncogene	0.699
Fgfr1	fibroblast growth factor receptor 1	0.661
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.638
Gsc	goosecoid homeobox	0.629
Gli2	GLI-Kruppel family member GLI2	0.604
Prrx1	paired related homeobox 1	0.601	Mouse
Runx2	runt related transcription factor 2	0.546
Hoxa1	homeobox A1	0.504
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.499
Msx2	homeobox, msh-like 2	0.481
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.409
Rarb	retinoic acid receptor, beta	0.353
Pax2	paired box gene 2	0.348
Pax6	paired box gene 6	0.347
Fgf10	fibroblast growth factor 10	0.326
Zeb1	zinc finger E-box binding homeobox 1	0.319
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.319
Foxg1	forkhead box G1	0.319
Alx4	aristaless-like homeobox 4	0.279
Phox2b	paired-like homeobox 2b	0.276
Bmp2	bone morphogenetic protein 2	0.222
Ntf3	neurotrophin 3	0.218
Acvr1	activin A receptor, type 1	0.217
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.216
Nog	noggin	0.212
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.201
Neurod1	neurogenic differentiation 1	0.191
Hoxa3	homeobox A3	0.177
Pitx1	paired-like homeodomain transcription factor 1	0.159
Hoxa2	homeobox A2	0.147
Pbx1	pre B-cell leukemia transcription factor 1	0.141
Twist2	twist homolog 2 (Drosophila)	0.141
Fgfr3	fibroblast growth factor receptor 3	0.139
Dlx6	distal-less homeobox 6	0.130
Tbx15	T-box 15	0.130
Neurog2	neurogenin 2	0.116
Sox2	SRY-box containing gene 2	0.116
Mn1	meningioma 1	0.114
Nkx3-2	NK3 homeobox 2	0.113
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.111
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.107
Nrg1	neuregulin 1	0.099
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.097
Sox11	SRY-box containing gene 11	0.095
Rarg	retinoic acid receptor, gamma	0.094
Lhx3	LIM homeobox protein 3	0.091
Gdnf	glial cell line derived neurotrophic factor	0.090
Phox2a	paired-like homeobox 2a	0.078	Mouse
Alx1	ALX homeobox 1	0.075
Chd7	chromodomain helicase DNA binding protein 7	0.075
Lmx1a	LIM homeobox transcription factor 1 alpha	0.073
Nrtn	neurturin	0.072
Vangl2	vang-like 2 (van gogh, Drosophila)	0.064
Dlx2	distal-less homeobox 2	0.063
Pax9	paired box gene 9	0.062
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.058
Jag1	jagged 1	0.058
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.057
En1	engrailed 1	0.055
Hoxb1	homeobox B1	0.050
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.048
Fgf3	fibroblast growth factor 3	0.048
Alx3	aristaless-like homeobox 3	0.048
Lmx1b	LIM homeobox transcription factor 1 beta	0.047
Rara	retinoic acid receptor, alpha	0.046
Col2a1	collagen, type II, alpha 1	0.046
Mesp1	mesoderm posterior 1	0.041
Hoxd13	homeobox D13	0.041
Nkx6-1	NK6 homeobox 1	0.040
Wnt1	wingless-related MMTV integration site 1	0.038
Hoxd11	homeobox D11	0.038
Neurod4	neurogenic differentiation 4	0.034
Meox2	mesenchyme homeobox 2	0.032
Hmx3	H6 homeobox 3	0.028
Foxd2	forkhead box D2	0.028
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.027
Hes1	hairy and enhancer of split 1 (Drosophila)	0.027
Twist1	twist homolog 1 (Drosophila)	0.027
Ece1	endothelin converting enzyme 1	0.025
Bdnf	brain derived neurotrophic factor	0.024
Neurog3	neurogenin 3	0.024
Ebf3	early B-cell factor 3	0.024
Sox10	SRY-box containing gene 10	0.023
Nhlh1	nescient helix loop helix 1	0.023
Hoxd3	homeobox D3	0.023
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.022
Tgfbr2	transforming growth factor, beta receptor II	0.022
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.022
Wnt3a	wingless-related MMTV integration site 3A	0.022
Lrp6	low density lipoprotein receptor-related protein 6	0.021
Fgf15	fibroblast growth factor 15	0.021
Shox2	short stature homeobox 2	0.021
Sox4	SRY-box containing gene 4	0.020
Foxi3	forkhead box I3	0.020
Neurog1	neurogenin 1	0.020
Pou1f1	POU domain, class 1, transcription factor 1	0.019
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.019
Prph	peripherin	0.019
Gata4	GATA binding protein 4	0.019
Hmx2	H6 homeobox 2	0.019
Hes5	hairy and enhancer of split 5 (Drosophila)	0.018
Myod1	myogenic differentiation 1	0.018
Onecut1	one cut domain, family member 1	0.018
Pitx3	paired-like homeodomain transcription factor 3	0.018
Col11a1	collagen, type XI, alpha 1	0.017
Tlx2	T-cell leukemia, homeobox 2	0.017
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.017
Foxd3	forkhead box D3	0.017
Grb10	growth factor receptor bound protein 10	0.016
Pdx1	pancreatic and duodenal homeobox 1	0.016
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.016
Sox3	SRY-box containing gene 3	0.016
Pax1	paired box gene 1	0.016
T	brachyury	0.016
Lhx1	LIM homeobox protein 1	0.015
Ptch1	patched homolog 1	0.015
Bmp5	bone morphogenetic protein 5	0.015
Emx1	empty spiracles homolog 1 (Drosophila)	0.015
Otx1	orthodenticle homolog 1 (Drosophila)	0.015
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.015
Gas1	growth arrest specific 1	0.015
Lhx5	LIM homeobox protein 5	0.015
Fgf4	fibroblast growth factor 4	0.015
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.015
Col9a1	collagen, type IX, alpha 1	0.015
Nf1	neurofibromatosis 1	0.014
Foxd1	forkhead box D1	0.014
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.014
Myog	myogenin	0.014
Rax	retina and anterior neural fold homeobox	0.014
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.014
Tlx3	T-cell leukemia, homeobox 3	0.014
Hoxc8	homeobox C8	0.014
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.014
Zic3	zinc finger protein of the cerebellum 3	0.014
Efna2	ephrin A2	0.014
Ptf1a	pancreas specific transcription factor, 1a	0.013
Uncx	UNC homeobox	0.013
Hmx1	H6 homeobox 1	0.013
Vegfa	vascular endothelial growth factor A	0.013
Bmper	BMP-binding endothelial regulator	0.013
Sox1	SRY-box containing gene 1	0.013
Pou4f3	POU domain, class 4, transcription factor 3	0.013
Ctnnb1	catenin (cadherin associated protein), beta 1	0.013
Slc26a5	solute carrier family 26, member 5	0.012
Mab21l2	mab-21-like 2 (C. elegans)	0.012
Sall3	sal-like 3 (Drosophila)	0.012
Sall4	sal-like 4 (Drosophila)	0.012
En2	engrailed 2	0.012
Lefty1	left right determination factor 1	0.012
Efnb2	ephrin B2	0.011
Hoxd1	homeobox D1	0.011
Trp63	transformation related protein 63	0.011
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.011
Hoxa11	homeobox A11	0.011
Pax7	paired box gene 7	0.011
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.011
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.011
Tal2	T-cell acute lymphocytic leukemia 2	0.011
Ntf5	neurotrophin 5	0.011
Plac1	placental specific protein 1	0.011
Dbh	dopamine beta hydroxylase	0.010
Prop1	paired like homeodomain factor 1	0.010
Fbln1	fibulin 1	0.010
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.010
Hoxa4	homeobox A4	0.010
Etv2	ets variant gene 2	0.010
Barx2	BarH-like homeobox 2	0.010