|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.999
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.998
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.995
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.988
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.988
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.986
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.985
|
Mouse |
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.974
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.971
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.971
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.971
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.957
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.952
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.950
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.950
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.947
|
|
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.942
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.942
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.940
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.935
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.935
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.932
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.927
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.925
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.921
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.921
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.920
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.916
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.908
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.908
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.907
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.905
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.905
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.899
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.897
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.893
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.886
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.884
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.884
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.882
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.877
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.876
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.870
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.866
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.863
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.862
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.860
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.856
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.855
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.854
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.854
|
Mouse |
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.853
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.853
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.853
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.850
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.849
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.846
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.846
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.843
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.842
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.842
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.841
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.837
|
Mouse |
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.837
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.836
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.836
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.835
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.827
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.824
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.824
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.824
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.817
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.815
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.809
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.804
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.803
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.798
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.795
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.795
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.793
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.792
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.788
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.785
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.783
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.782
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.773
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.772
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.772
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.772
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.770
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.769
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.769
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.761
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.756
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.756
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.746
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.743
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.739
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.738
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.733
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.729
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.728
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.726
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.726
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.721
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.720
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.710
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.710
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.706
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.703
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.702
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.700
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.700
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.700
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.699
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.698
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.697
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.697
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.694
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.693
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.691
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.691
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.690
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.685
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.684
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.684
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.683
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.683
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.683
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.679
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.678
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.677
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.677
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.676
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.676
|
Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.674
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.674
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.672
|
|
|
|
icosanoid transport
|
GO:0071715 |
14 |
0.668
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.667
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.667
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.666
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.663
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.660
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.658
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.654
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.651
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.649
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.646
|
|
|
|
fatty acid transport
|
GO:0015908 |
28 |
0.645
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.645
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.640
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.637
|
Mouse |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.637
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.636
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.635
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.630
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.627
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.626
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.623
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.617
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.615
|
|
|
|
negative regulation of odontogenesis of dentin containing tooth
|
GO:0042489 |
1 |
0.612
|
|
|
|
translation
|
GO:0006412 |
93 |
0.611
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.610
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.609
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.608
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.606
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.606
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.604
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.599
|
Mouse Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.596
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.595
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.595
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.594
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.593
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.591
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.590
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.589
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.585
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.585
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.581
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.580
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.576
|
|
|
|
icosanoid secretion
|
GO:0032309 |
12 |
0.575
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.574
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.573
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.569
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.568
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.566
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.563
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.559
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.557
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.555
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.554
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.551
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.551
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.550
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.548
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.548
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.547
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.546
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.542
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.541
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.541
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.541
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.541
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.531
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.528
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.524
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.520
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.514
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.512
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.509
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.504
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.503
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.502
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.501
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.501
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.501
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.500
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.496
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.493
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.492
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.488
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.486
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.486
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.486
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.486
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.485
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.485
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.483
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.483
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.483
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.480
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.478
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.477
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.475
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.474
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.473
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.471
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.471
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.471
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.465
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.465
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.461
|
|
|
|
negative regulation of interleukin 13 secretion
|
GO:2000666 |
1 |
0.461
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.460
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.458
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.454
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.452
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.452
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
4 |
0.450
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.450
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.448
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.448
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.445
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.443
|
|
|
|
regulation of glucose import
|
GO:0046324 |
26 |
0.440
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.438
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.436
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.427
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.427
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.426
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.425
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.424
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.423
|
Fly |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.422
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.420
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.419
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.419
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.418
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.417
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.416
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.415
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.414
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.412
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.410
|
|
|
|
fatty acid derivative transport
|
GO:1901571 |
14 |
0.410
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.408
|
Fly |
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.408
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.408
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.407
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.403
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.403
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.402
|
|
|
|
positive regulation of hair cycle
|
GO:0042635 |
7 |
0.402
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.399
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.398
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.395
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.394
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.393
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.392
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.392
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.390
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.388
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.387
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.382
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.380
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.379
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
8 |
0.378
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.378
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.377
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.374
|
|
|
|
regulation of fever generation
|
GO:0031620 |
6 |
0.372
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.370
|
Mouse |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.369
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.369
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.367
|
Fly |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.367
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.365
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.360
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.357
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.357
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.356
|
|
|
|
regulation of prostaglandin secretion
|
GO:0032306 |
5 |
0.356
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.356
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.356
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.355
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.355
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.354
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.353
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.352
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.351
|
Mouse |
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.350
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.348
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.348
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.346
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.345
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.344
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.342
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.340
|
|
|
|
acid secretion
|
GO:0046717 |
33 |
0.339
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.337
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.335
|
Fly |
|
|
organic acid transport
|
GO:0015849 |
101 |
0.333
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.333
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.331
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.327
|
Fly |
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.323
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.322
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.322
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
8 |
0.321
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.321
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.320
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.320
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.320
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.320
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.318
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.317
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.317
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.315
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.315
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.314
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.313
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
6 |
0.313
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
8 |
0.311
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.311
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.310
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.308
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
11 |
0.307
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.306
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.301
|
Mouse Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.299
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.298
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.296
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.296
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.295
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.291
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.290
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.289
|
|
|
|
positive regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002925 |
6 |
0.289
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.286
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.285
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.284
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.284
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.281
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.281
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.281
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.279
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.278
|
Mouse Fly |
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.278
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.277
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.277
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.274
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.274
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.272
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.270
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.267
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.266
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.264
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.263
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.263
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.261
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.261
|
Mouse |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.261
|
|
|
|
regulation of heat generation
|
GO:0031650 |
8 |
0.260
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.257
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.255
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.252
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.251
|
|
|
|
osteoclast development
|
GO:0036035 |
9 |
0.250
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.249
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.249
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.245
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.245
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.242
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.242
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.241
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.241
|
Mouse |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.239
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.239
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.239
|
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.239
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.238
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.235
|
|
|
|
negative regulation of interleukin 13 production
|
GO:0032696 |
2 |
0.234
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.232
|
|
|
|
retinal cell programmed cell death
|
GO:0046666 |
8 |
0.231
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.230
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.229
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.228
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.227
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.226
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.225
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
6 |
0.225
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.224
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.223
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.222
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.220
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.220
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.218
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.217
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.215
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.213
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.213
|
Mouse |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.211
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.210
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.205
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.204
|
|
|
|
positive regulation of translation
|
GO:0045727 |
19 |
0.201
|
Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.200
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.198
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.197
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.194
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.194
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.191
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
8 |
0.191
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.191
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.191
|
Fly |
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.191
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.190
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.190
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.188
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.187
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.185
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.184
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.182
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.182
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.179
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.179
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.179
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.178
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.178
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.175
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.174
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.173
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.173
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.173
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.172
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.172
|
|
|
|
mature b cell differentiation involved in immune response
|
GO:0002313 |
9 |
0.172
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.171
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.171
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.169
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.169
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.169
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.169
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.168
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.168
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.167
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.166
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.166
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.166
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.165
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.164
|
|
|
|
circadian temperature homeostasis
|
GO:0060086 |
2 |
0.163
|
|
|
|
melanin metabolic process
|
GO:0006582 |
12 |
0.162
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.161
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.161
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.161
|
|
|
|
histamine secretion
|
GO:0001821 |
1 |
0.161
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.161
|
|
