Mus musculus

36 known processes

Plat

plasminogen activator, tissue

(Aliases: AW212668,AU020998,tPA,MGC18508,D8Ertd2e)

Plat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ossification GO:0001503 216 0.727
chemotaxis GO:0006935 247 0.712
cell adhesion GO:0007155 329 0.698
blood vessel morphogenesis GO:0048514 285 0.694
regulation of angiogenesis GO:0045765 81 0.678
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.664
Mouse
angiogenesis GO:0001525 201 0.599
cell matrix adhesion GO:0007160 68 0.532
monocarboxylic acid metabolic process GO:0032787 191 0.451
response to organonitrogen compound GO:0010243 246 0.439
Rat
mapk cascade GO:0000165 281 0.414
Mouse
positive regulation of cell death GO:0010942 224 0.383
regulation of cell adhesion mediated by integrin GO:0033628 13 0.376
positive regulation of programmed cell death GO:0043068 218 0.373
regulation of ovulation GO:0060278 3 0.373
Rat
cell substrate adhesion GO:0031589 130 0.359
regulation of cell migration GO:0030334 219 0.349
regulation of mapk cascade GO:0043408 248 0.348
Mouse
anatomical structure maturation GO:0071695 49 0.348
regulation of reproductive process GO:2000241 66 0.341
Rat
positive regulation of cell migration GO:0030335 109 0.339
synaptic transmission GO:0007268 329 0.327
Rat
reactive oxygen species metabolic process GO:0072593 84 0.326
response to organic cyclic compound GO:0014070 198 0.324
Rat
regulation of cell substrate adhesion GO:0010810 73 0.323
ameboidal type cell migration GO:0001667 128 0.323
amine metabolic process GO:0009308 45 0.315
positive regulation of mapk cascade GO:0043410 170 0.310
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.309
response to hyperoxia GO:0055093 2 0.305
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.295
ovulation GO:0030728 15 0.286
Rat
developmental maturation GO:0021700 193 0.284
positive regulation of inflammatory response GO:0050729 47 0.276
regulation of vasculature development GO:1901342 88 0.275
trabecula morphogenesis GO:0061383 40 0.272
positive regulation of angiogenesis GO:0045766 46 0.269
regulation of cell adhesion GO:0030155 154 0.263
regulation of apoptotic signaling pathway GO:2001233 197 0.258
Mouse
response to growth factor GO:0070848 198 0.250
cellular response to organic cyclic compound GO:0071407 87 0.250
Rat
cellular amine metabolic process GO:0044106 44 0.250
regulation of cellular ketone metabolic process GO:0010565 66 0.249
response to increased oxygen levels GO:0036296 2 0.230
nitrogen compound transport GO:0071705 271 0.229
regulation of cell motility GO:2000145 236 0.225
positive regulation of cellular amine metabolic process GO:0033240 5 0.224
response to nicotine GO:0035094 6 0.221
inflammatory response GO:0006954 244 0.216
positive regulation of protein phosphorylation GO:0001934 242 0.212
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.206
wound healing GO:0042060 157 0.205
Mouse Rat
tissue migration GO:0090130 68 0.198
skeletal system morphogenesis GO:0048705 203 0.197
anatomical structure homeostasis GO:0060249 145 0.195
Mouse
response to lipopolysaccharide GO:0032496 128 0.194
fatty acid metabolic process GO:0006631 121 0.190
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.190
regulation of cell activation GO:0050865 289 0.187
lipid biosynthetic process GO:0008610 179 0.187
negative regulation of cell migration GO:0030336 59 0.182
regulation of ion transmembrane transport GO:0034765 119 0.179
regulation of neuron differentiation GO:0045664 281 0.174
male gamete generation GO:0048232 285 0.174
leukocyte chemotaxis GO:0030595 69 0.172
regulation of reactive oxygen species metabolic process GO:2000377 40 0.167
cellular response to biotic stimulus GO:0071216 92 0.167
muscle tissue development GO:0060537 308 0.166
response to molecule of bacterial origin GO:0002237 143 0.163
cellular response to lipid GO:0071396 145 0.159
Rat
positive regulation of smooth muscle cell migration GO:0014911 4 0.158
organ growth GO:0035265 117 0.157
cellular ketone metabolic process GO:0042180 84 0.156
cellular response to fluid shear stress GO:0071498 4 0.154
developmental growth involved in morphogenesis GO:0060560 138 0.149
myeloid leukocyte migration GO:0097529 57 0.149
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.149
Mouse
urogenital system development GO:0001655 261 0.148
tissue remodeling GO:0048771 102 0.145
coagulation GO:0050817 78 0.144
Mouse
peptide transport GO:0015833 133 0.144
morphogenesis of a branching structure GO:0001763 203 0.144
Mouse
prostaglandin metabolic process GO:0006693 11 0.143
regulation of wound healing GO:0061041 40 0.137
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.135
muscle system process GO:0003012 141 0.134
epithelium migration GO:0090132 63 0.133
epithelial cell migration GO:0010631 63 0.130
regulation of peptidase activity GO:0052547 96 0.128
endothelial cell migration GO:0043542 44 0.128
positive regulation of cell motility GO:2000147 116 0.127
sphingolipid metabolic process GO:0006665 45 0.126
regulation of map kinase activity GO:0043405 120 0.123
Mouse
labyrinthine layer development GO:0060711 49 0.123
Mouse
response to acid chemical GO:0001101 111 0.122
negative regulation of molecular function GO:0044092 258 0.120
ras protein signal transduction GO:0007265 77 0.119
regulation of chemotaxis GO:0050920 53 0.119
positive regulation of muscle contraction GO:0045933 10 0.118
positive regulation of protein modification process GO:0031401 299 0.118
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.117
salivary gland development GO:0007431 37 0.116
Mouse
cellular amino acid metabolic process GO:0006520 103 0.116
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.116
regulation of neuron projection development GO:0010975 169 0.115
positive regulation of apoptotic process GO:0043065 217 0.114
metal ion homeostasis GO:0055065 189 0.114
regulation of hydrolase activity GO:0051336 246 0.114
kidney development GO:0001822 213 0.111
cellular lipid metabolic process GO:0044255 323 0.110
spermatogenesis GO:0007283 284 0.109
epithelial cell proliferation GO:0050673 174 0.109
regulation of receptor activity GO:0010469 41 0.107
leukocyte migration GO:0050900 124 0.106
Mouse
positive regulation of synaptic plasticity GO:0031915 4 0.106
negative regulation of cell proliferation GO:0008285 296 0.105
neuron projection guidance GO:0097485 141 0.105
regulation of rho protein signal transduction GO:0035023 71 0.105
regulation of ion transport GO:0043269 215 0.104
ribose phosphate metabolic process GO:0019693 291 0.104
activation of mapk activity GO:0000187 59 0.104
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.103
fibrinolysis GO:0042730 3 0.102
Mouse
regulation of fatty acid metabolic process GO:0019217 28 0.102
regulation of system process GO:0044057 200 0.101
antibacterial peptide secretion GO:0002779 1 0.101
fat cell differentiation GO:0045444 160 0.100
rho protein signal transduction GO:0007266 32 0.100
placenta development GO:0001890 140 0.098
Mouse
renal system development GO:0072001 225 0.098
positive regulation of nervous system development GO:0051962 221 0.098
response to peptide hormone GO:0043434 127 0.096
Rat
integrin mediated signaling pathway GO:0007229 27 0.095
cation transport GO:0006812 399 0.095
smooth muscle cell migration GO:0014909 10 0.094
extracellular matrix organization GO:0030198 147 0.092
hemostasis GO:0007599 78 0.091
Mouse
icosanoid metabolic process GO:0006690 33 0.090
cell chemotaxis GO:0060326 81 0.089
biomineral tissue development GO:0031214 64 0.089
regulation of epithelial cell migration GO:0010632 35 0.089
blood coagulation GO:0007596 76 0.088
Mouse
response to alkaloid GO:0043279 34 0.088
negative regulation of cell motility GO:2000146 61 0.088
ribonucleotide metabolic process GO:0009259 291 0.087
regulation of coagulation GO:0050818 31 0.087
Mouse
positive regulation of proteolysis GO:0045862 85 0.087
axon guidance GO:0007411 141 0.086
regulation of inflammatory response GO:0050727 147 0.086
purine ribonucleotide metabolic process GO:0009150 290 0.085
heat generation GO:0031649 13 0.085
regulation of ras protein signal transduction GO:0046578 114 0.085
regulation of multi organism process GO:0043900 111 0.083
Rat
positive regulation of cell adhesion GO:0045785 80 0.083
negative regulation of behavior GO:0048521 14 0.083
regulation of cell projection organization GO:0031344 206 0.083
carboxylic acid biosynthetic process GO:0046394 86 0.083
cartilage development GO:0051216 140 0.083
cellular response to cytokine stimulus GO:0071345 189 0.082
gliogenesis GO:0042063 141 0.082
carbohydrate homeostasis GO:0033500 128 0.082
ion transmembrane transport GO:0034220 361 0.082
divalent inorganic cation homeostasis GO:0072507 138 0.081
oxidation reduction process GO:0055114 342 0.081
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.081
purine containing compound metabolic process GO:0072521 311 0.081
regulation of secretion GO:0051046 274 0.081
regulation of blood pressure GO:0008217 93 0.080
organic acid biosynthetic process GO:0016053 86 0.080
immune effector process GO:0002252 321 0.080
regulation of protein serine threonine kinase activity GO:0071900 157 0.079
Mouse
blood circulation GO:0008015 195 0.079
regulation of membrane potential GO:0042391 192 0.078
unsaturated fatty acid metabolic process GO:0033559 31 0.078
kidney epithelium development GO:0072073 121 0.077
positive regulation of kinase activity GO:0033674 155 0.077
Mouse
multi multicellular organism process GO:0044706 109 0.077
Mouse
nucleotide metabolic process GO:0009117 332 0.077
axonogenesis GO:0007409 274 0.076
regulation of epithelial cell proliferation GO:0050678 141 0.076
regulation of hepatocyte proliferation GO:2000345 6 0.075
vasoconstriction GO:0042310 27 0.074
negative regulation of immune system process GO:0002683 209 0.074
cellular response to lipopolysaccharide GO:0071222 77 0.074
response to nutrient levels GO:0031667 109 0.074
developmental cell growth GO:0048588 84 0.073
small gtpase mediated signal transduction GO:0007264 97 0.073
regulation of acute inflammatory response GO:0002673 27 0.072
cellular response to oxidative stress GO:0034599 76 0.071
circulatory system process GO:0003013 197 0.071
sprouting angiogenesis GO:0002040 26 0.071
fever generation GO:0001660 7 0.071
single organismal cell cell adhesion GO:0016337 131 0.070
bone mineralization GO:0030282 54 0.070
regulation of action potential GO:0098900 4 0.070
response to nitric oxide GO:0071731 4 0.070
defense response to other organism GO:0098542 197 0.069
glucose homeostasis GO:0042593 128 0.069
response to oxygen levels GO:0070482 62 0.068
regulation of hormone levels GO:0010817 211 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
granulocyte chemotaxis GO:0071621 39 0.068
negative regulation of response to wounding GO:1903035 77 0.068
Mouse
striated muscle tissue development GO:0014706 293 0.068
positive regulation of brown fat cell differentiation GO:0090336 4 0.067
response to monosaccharide GO:0034284 67 0.067
positive regulation of behavior GO:0048520 40 0.067
neuron death GO:0070997 154 0.067
regulation of tube size GO:0035150 57 0.067
regulation of cellular amine metabolic process GO:0033238 20 0.067
response to decreased oxygen levels GO:0036293 59 0.066
regulation of transferase activity GO:0051338 263 0.066
Mouse
negative regulation of coagulation GO:0050819 11 0.066
Mouse
t cell activation GO:0042110 289 0.065
protein processing GO:0016485 163 0.065
Human
cell growth GO:0016049 130 0.065
icosanoid biosynthetic process GO:0046456 15 0.065
calcium ion transport GO:0006816 159 0.064
positive regulation of protein kinase activity GO:0045860 144 0.064
Mouse
synaptic transmission glutamatergic GO:0035249 36 0.064
Rat
cellular calcium ion homeostasis GO:0006874 119 0.063
catecholamine secretion GO:0050432 15 0.062
skeletal system development GO:0001501 356 0.062
regulation of fibroblast growth factor production GO:0090270 4 0.062
multicellular organismal homeostasis GO:0048871 164 0.062
peptidyl amino acid modification GO:0018193 336 0.061
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.061
memory GO:0007613 58 0.061
positive regulation of map kinase activity GO:0043406 84 0.061
Mouse
positive regulation of homeostatic process GO:0032846 64 0.060
cellular response to ammonium ion GO:0071242 2 0.060
positive regulation of response to wounding GO:1903036 66 0.059
placenta blood vessel development GO:0060674 31 0.058
Mouse
response to steroid hormone GO:0048545 56 0.058
Rat
regulation of neuron death GO:1901214 134 0.058
fatty acid derivative metabolic process GO:1901568 33 0.058
muscle contraction GO:0006936 101 0.057
multicellular organismal signaling GO:0035637 91 0.057
salivary gland morphogenesis GO:0007435 33 0.057
Mouse
response to catecholamine GO:0071869 4 0.057
organic hydroxy compound transport GO:0015850 93 0.057
regulation of protein kinase activity GO:0045859 232 0.057
Mouse
epithelial tube morphogenesis GO:0060562 303 0.056
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.056
negative regulation of hydrolase activity GO:0051346 71 0.055
granulocyte migration GO:0097530 43 0.055
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.054
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.054
negative regulation of cell adhesion GO:0007162 45 0.054
regulation of response to wounding GO:1903034 189 0.053
Mouse
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.053
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.053
regulation of monooxygenase activity GO:0032768 7 0.053
regulation of bone remodeling GO:0046850 28 0.053
nitric oxide metabolic process GO:0046209 25 0.053
extracellular structure organization GO:0043062 148 0.052
hindbrain development GO:0030902 128 0.052
regulation of fat cell differentiation GO:0045598 81 0.052
positive regulation of neuron differentiation GO:0045666 141 0.052
single organism cell adhesion GO:0098602 156 0.051
purine nucleoside metabolic process GO:0042278 241 0.050
small molecule biosynthetic process GO:0044283 132 0.050
divalent metal ion transport GO:0070838 172 0.050
fatty acid derivative biosynthetic process GO:1901570 15 0.050
cellular homeostasis GO:0019725 240 0.050
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.050
Human
regulation of neurotransmitter levels GO:0001505 87 0.050
regulation of kinase activity GO:0043549 249 0.050
Mouse
response to amino acid GO:0043200 37 0.049
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.049
regulation of tissue remodeling GO:0034103 38 0.049
camera type eye development GO:0043010 266 0.048
response to oxidative stress GO:0006979 123 0.048
embryonic placenta development GO:0001892 98 0.048
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.048
nephron development GO:0072006 109 0.048
response to inorganic substance GO:0010035 96 0.048
heart morphogenesis GO:0003007 178 0.048
muscle cell differentiation GO:0042692 261 0.048
Mouse
regulation of organelle organization GO:0033043 289 0.047
peptide secretion GO:0002790 114 0.047
negative regulation of ion transport GO:0043271 28 0.047
cytokine production GO:0001816 319 0.047
multicellular organism growth GO:0035264 161 0.047
cellular response to extracellular stimulus GO:0031668 81 0.046
cellular metal ion homeostasis GO:0006875 151 0.046
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.046
aromatic compound catabolic process GO:0019439 286 0.046
reactive nitrogen species metabolic process GO:2001057 0 0.046
organonitrogen compound catabolic process GO:1901565 264 0.046
female gamete generation GO:0007292 74 0.045
Rat
unsaturated fatty acid biosynthetic process GO:0006636 15 0.045
response to reactive oxygen species GO:0000302 56 0.045
actin cytoskeleton organization GO:0030036 220 0.045
smooth muscle contraction GO:0006939 44 0.045
telencephalon development GO:0021537 186 0.045
negative regulation of fat cell differentiation GO:0045599 36 0.045
regulation of blood circulation GO:1903522 93 0.045
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.044
trabecula formation GO:0060343 24 0.044
glycosyl compound metabolic process GO:1901657 246 0.044
nucleotide catabolic process GO:0009166 217 0.044
regulation of anatomical structure size GO:0090066 178 0.043
negative regulation of cation channel activity GO:2001258 1 0.043
protein catabolic process GO:0030163 221 0.043
cellular response to monosaccharide stimulus GO:0071326 47 0.043
cellular chemical homeostasis GO:0055082 215 0.043
regulation of neuron apoptotic process GO:0043523 122 0.043
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.043
regulation of homeostatic process GO:0032844 182 0.042
organic anion transport GO:0015711 137 0.042
regulation of cellular component biogenesis GO:0044087 181 0.042
mesenchyme development GO:0060485 152 0.041
response to transforming growth factor beta GO:0071559 88 0.041
maternal process involved in female pregnancy GO:0060135 32 0.041
blood vessel endothelial cell migration GO:0043534 23 0.041
cardiac muscle tissue development GO:0048738 130 0.041
organonitrogen compound biosynthetic process GO:1901566 192 0.041
multicellular organismal response to stress GO:0033555 62 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
Human
nitric oxide biosynthetic process GO:0006809 25 0.041
regulation of synaptic plasticity GO:0048167 87 0.040
Rat
transmission of nerve impulse GO:0019226 76 0.040
regulation of cellular response to growth factor stimulus GO:0090287 82 0.040
branching morphogenesis of an epithelial tube GO:0048754 159 0.040
nucleoside metabolic process GO:0009116 246 0.040
positive regulation of epithelial cell migration GO:0010634 19 0.040
response to alcohol GO:0097305 48 0.040
Rat
wnt signaling pathway GO:0016055 188 0.039
negative regulation of vasculature development GO:1901343 26 0.039
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
monoamine transport GO:0015844 33 0.039
cyclic nucleotide metabolic process GO:0009187 59 0.039
brown fat cell differentiation GO:0050873 36 0.038
regulation of blood coagulation GO:0030193 28 0.038
Mouse
ureteric bud development GO:0001657 94 0.038
response to extracellular stimulus GO:0009991 127 0.038
regulation of cell cycle GO:0051726 281 0.038
regulation of defense response GO:0031347 233 0.038
positive regulation of cell development GO:0010720 237 0.038
positive regulation of cell substrate adhesion GO:0010811 47 0.037
female gonad development GO:0008585 71 0.037
positive regulation of chemotaxis GO:0050921 38 0.037
extrinsic apoptotic signaling pathway GO:0097191 126 0.037
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.037
positive regulation of binding GO:0051099 49 0.037
membrane lipid metabolic process GO:0006643 53 0.037
response to light stimulus GO:0009416 135 0.037
response to hepatocyte growth factor GO:0035728 2 0.037
regulation of nucleotide metabolic process GO:0006140 169 0.036
response to low density lipoprotein particle GO:0055098 2 0.036
muscle cell migration GO:0014812 19 0.036
tissue regeneration GO:0042246 22 0.036
Mouse
pallium development GO:0021543 120 0.036
positive regulation of hydrolase activity GO:0051345 148 0.036
neuronal action potential GO:0019228 54 0.036
transmembrane transport GO:0055085 412 0.036
purine ribonucleoside catabolic process GO:0046130 205 0.036
regulation of muscle contraction GO:0006937 49 0.036
positive regulation of cell projection organization GO:0031346 95 0.035
regulation of peptidyl serine phosphorylation GO:0033135 39 0.035
cognition GO:0050890 149 0.035
positive regulation of vasoconstriction GO:0045907 4 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
negative regulation of proteolysis GO:0045861 74 0.035
Human
negative regulation of wound healing GO:0061045 14 0.035
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.035
regulation of synaptic transmission glutamatergic GO:0051966 19 0.035
carboxylic acid transport GO:0046942 100 0.035
peptidyl serine phosphorylation GO:0018105 74 0.034
branching involved in salivary gland morphogenesis GO:0060445 26 0.034
Mouse
ribonucleoside catabolic process GO:0042454 206 0.034
cellular protein catabolic process GO:0044257 155 0.034
gland development GO:0048732 330 0.034
Mouse
intussusceptive angiogenesis GO:0002041 2 0.034
macromolecule catabolic process GO:0009057 281 0.034
regulation of hemostasis GO:1900046 28 0.034
Mouse
positive regulation of transferase activity GO:0051347 167 0.033
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
cation homeostasis GO:0055080 212 0.033
skin development GO:0043588 220 0.033
gtp catabolic process GO:0006184 143 0.033
neuron neuron synaptic transmission GO:0007270 69 0.033
Rat
regulation of purine nucleotide metabolic process GO:1900542 169 0.033
response to hypoxia GO:0001666 58 0.033
positive regulation of leukocyte differentiation GO:1902107 86 0.033
sensory system development GO:0048880 3 0.033
cellular response to external stimulus GO:0071496 88 0.033
regulation of smooth muscle contraction GO:0006940 22 0.033
forebrain development GO:0030900 302 0.033
endocytosis GO:0006897 168 0.032
morphogenesis of a branching epithelium GO:0061138 193 0.032
Mouse
positive regulation of phospholipase activity GO:0010518 3 0.032
negative regulation of protein processing GO:0010955 79 0.032
Human
muscle adaptation GO:0043500 39 0.032
regulation of organ morphogenesis GO:2000027 144 0.032
Mouse
purine nucleoside catabolic process GO:0006152 205 0.032
learning or memory GO:0007611 148 0.031
regulation of ras gtpase activity GO:0032318 88 0.031
hair follicle development GO:0001942 85 0.031
nucleoside catabolic process GO:0009164 206 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.031
negative regulation of cellular amine metabolic process GO:0033239 1 0.031
guanosine containing compound metabolic process GO:1901068 144 0.031
regulation of eosinophil migration GO:2000416 2 0.031
negative regulation of blood coagulation GO:0030195 11 0.031
Mouse
epidermis development GO:0008544 187 0.031
monocarboxylic acid biosynthetic process GO:0072330 61 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
positive regulation of acute inflammatory response GO:0002675 16 0.031
tissue homeostasis GO:0001894 115 0.031
regulation of heat generation GO:0031650 8 0.031
organophosphate catabolic process GO:0046434 232 0.030
negative regulation of protein maturation GO:1903318 79 0.030
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.030
regulation of fever generation GO:0031620 6 0.030
regulation of blood vessel size GO:0050880 56 0.030
peptidyl serine modification GO:0018209 83 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
ribonucleotide catabolic process GO:0009261 208 0.030
neuron projection extension GO:1990138 64 0.029
connective tissue development GO:0061448 179 0.029
liver development GO:0001889 66 0.029
Mouse
stem cell differentiation GO:0048863 268 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
positive regulation of blood circulation GO:1903524 22 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.029
positive regulation of neuron projection development GO:0010976 79 0.029
antibacterial peptide biosynthetic process GO:0002780 2 0.029
negative regulation of chemotaxis GO:0050922 11 0.029
protein maturation GO:0051604 176 0.029
Human
membrane organization GO:0061024 245 0.028
positive regulation of smooth muscle contraction GO:0045987 7 0.028
antimicrobial peptide biosynthetic process GO:0002777 2 0.028
regulation of extent of cell growth GO:0061387 52 0.028
lateral line system development GO:0048925 1 0.028
bone resorption GO:0045453 38 0.028
prostanoid biosynthetic process GO:0046457 8 0.028
mesenchymal cell development GO:0014031 93 0.028
phagocytosis GO:0006909 66 0.028
retina development in camera type eye GO:0060041 119 0.028
metencephalon development GO:0022037 89 0.027
cellular response to epinephrine stimulus GO:0071872 3 0.027
growth involved in heart morphogenesis GO:0003241 4 0.027
regulation of cell cycle process GO:0010564 160 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
regeneration GO:0031099 38 0.027
Mouse
regulation of metal ion transport GO:0010959 106 0.027
lipid oxidation GO:0034440 29 0.027
morphogenesis of embryonic epithelium GO:0016331 159 0.027
cellular response to decreased oxygen levels GO:0036294 18 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
regulation of cell size GO:0008361 72 0.026
mesonephric tubule development GO:0072164 94 0.026
regulation of serotonin uptake GO:0051611 2 0.026
cellular response to inorganic substance GO:0071241 37 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
sequestering of metal ion GO:0051238 19 0.026
regulation of cytoskeleton organization GO:0051493 122 0.026
respiratory system development GO:0060541 190 0.026
regulation of cell shape GO:0008360 39 0.026
canonical wnt signaling pathway GO:0060070 130 0.026
regulation of sphingolipid biosynthetic process GO:0090153 1 0.026
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.026
peptide hormone secretion GO:0030072 109 0.026
organic acid transport GO:0015849 101 0.026
fibroblast growth factor production GO:0090269 4 0.025
response to iron ion GO:0010039 4 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.025
axon ensheathment GO:0008366 76 0.025
lymphocyte differentiation GO:0030098 242 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
response to radiation GO:0009314 165 0.025
heart trabecula morphogenesis GO:0061384 26 0.025
lymphocyte migration GO:0072676 26 0.025
regulation of fatty acid oxidation GO:0046320 10 0.025
negative regulation of protein modification process GO:0031400 163 0.025
negative regulation of cellular catabolic process GO:0031330 47 0.025
bone development GO:0060348 120 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
regulation of postsynaptic membrane potential GO:0060078 48 0.025
regulation of cellular component size GO:0032535 121 0.025
positive regulation of axon extension GO:0045773 20 0.025
response to ammonium ion GO:0060359 21 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
glomerulus development GO:0032835 40 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
regulation of cytokine production GO:0001817 266 0.024

Plat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.260
nervous system disease DOID:863 0 0.260
central nervous system disease DOID:331 0 0.140
disease of mental health DOID:150 0 0.073
neurodegenerative disease DOID:1289 0 0.057
retinal disease DOID:5679 0 0.042
retinal degeneration DOID:8466 0 0.042
sensory system disease DOID:0050155 0 0.042
eye and adnexa disease DOID:1492 0 0.042
eye disease DOID:5614 0 0.042