Mus musculus

52 known processes

Plau

plasminogen activator, urokinase

(Aliases: uPA,u-PA)

Plau biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
branching involved in salivary gland morphogenesis GO:0060445 26 0.981
Mouse
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.951
Mouse
morphogenesis of a branching structure GO:0001763 203 0.855
Mouse
keratinocyte migration GO:0051546 3 0.808
mapk cascade GO:0000165 281 0.752
Mouse
mesenchymal epithelial cell signaling GO:0060638 9 0.723
Mouse
mononuclear cell migration GO:0071674 8 0.664
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.641
Mouse
muscle cell differentiation GO:0042692 261 0.628
Mouse
hemostasis GO:0007599 78 0.614
salivary gland development GO:0007431 37 0.608
Mouse
leukocyte migration GO:0050900 124 0.605
Mouse
positive regulation of programmed cell death GO:0043068 218 0.603
blood vessel morphogenesis GO:0048514 285 0.602
Rat
cation homeostasis GO:0055080 212 0.570
cytokine production GO:0001816 319 0.557
negative regulation of response to wounding GO:1903035 77 0.553
response to molecule of bacterial origin GO:0002237 143 0.525
Rat
regulation of apoptotic signaling pathway GO:2001233 197 0.521
Mouse
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.519
Mouse
chemotaxis GO:0006935 247 0.507
calcium ion transport GO:0006816 159 0.501
regulation of system process GO:0044057 200 0.486
response to lipopolysaccharide GO:0032496 128 0.476
Rat
cellular response to lipid GO:0071396 145 0.474
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.470
Mouse
placenta blood vessel development GO:0060674 31 0.456
Mouse
cellular homeostasis GO:0019725 240 0.452
Mouse Rat
placenta development GO:0001890 140 0.447
Mouse
positive regulation of defense response GO:0031349 124 0.445
wound healing GO:0042060 157 0.444
extrinsic apoptotic signaling pathway GO:0097191 126 0.443
Mouse
positive regulation of cell death GO:0010942 224 0.442
apoptotic signaling pathway GO:0097190 306 0.410
Mouse
regulation of protein transport GO:0051223 163 0.407
cell differentiation involved in embryonic placenta development GO:0060706 26 0.406
Mouse
regulation of organ morphogenesis GO:2000027 144 0.401
Mouse Rat
cation transport GO:0006812 399 0.390
synaptic transmission GO:0007268 329 0.388
response to decreased oxygen levels GO:0036293 59 0.387
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.382
Mouse
positive regulation of inflammatory response GO:0050729 47 0.375
activation of mapk activity GO:0000187 59 0.373
Mouse
cellular response to biotic stimulus GO:0071216 92 0.368
Rat
regulation of mapk cascade GO:0043408 248 0.366
Mouse
negative regulation of protein processing GO:0010955 79 0.363
regulation of transferase activity GO:0051338 263 0.359
Mouse
regulation of defense response GO:0031347 233 0.358
positive regulation of transferase activity GO:0051347 167 0.353
Mouse
regulation of response to wounding GO:1903034 189 0.351
exocrine system development GO:0035272 45 0.351
Mouse
salivary gland morphogenesis GO:0007435 33 0.347
Mouse
cellular amine metabolic process GO:0044106 44 0.341
myoblast proliferation GO:0051450 11 0.334
Mouse
positive regulation of vasoconstriction GO:0045907 4 0.334
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.332
Mouse
regulation of inflammatory response GO:0050727 147 0.327
myoblast differentiation GO:0045445 52 0.327
Mouse
response to organic cyclic compound GO:0014070 198 0.320
Rat
regulation of protein kinase activity GO:0045859 232 0.318
Mouse
regulation of multi organism process GO:0043900 111 0.316
Rat
morphogenesis of a branching epithelium GO:0061138 193 0.316
Mouse
coagulation GO:0050817 78 0.315
divalent inorganic cation homeostasis GO:0072507 138 0.313
regulation of cytokine production GO:0001817 266 0.306
divalent inorganic cation transport GO:0072511 178 0.303
ameboidal type cell migration GO:0001667 128 0.302
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.300
positive regulation of mapk cascade GO:0043410 170 0.295
Mouse
regulation of ion transport GO:0043269 215 0.293
negative regulation of cell proliferation GO:0008285 296 0.284
blood coagulation GO:0007596 76 0.281
extracellular matrix organization GO:0030198 147 0.277
positive regulation of kinase activity GO:0033674 155 0.265
Mouse
regulation of fat cell differentiation GO:0045598 81 0.264
regulation of ovulation GO:0060278 3 0.262
Rat
response to oxygen levels GO:0070482 62 0.254
cytokine secretion GO:0050663 72 0.250
regulation of map kinase activity GO:0043405 120 0.249
Mouse
negative regulation of blood pressure GO:0045776 22 0.248
inflammatory response GO:0006954 244 0.248
labyrinthine layer development GO:0060711 49 0.247
Mouse
myeloid cell differentiation GO:0030099 233 0.241
smooth muscle contraction GO:0006939 44 0.238
angiogenesis GO:0001525 201 0.237
Rat
ion transmembrane transport GO:0034220 361 0.234
reactive oxygen species biosynthetic process GO:1903409 8 0.232
regulation of cell activation GO:0050865 289 0.229
divalent metal ion transport GO:0070838 172 0.226
cellular divalent inorganic cation homeostasis GO:0072503 127 0.224
positive regulation of cytokine production GO:0001819 174 0.222
regulation of body fluid levels GO:0050878 162 0.220
gland development GO:0048732 330 0.219
Mouse Rat
multi multicellular organism process GO:0044706 109 0.215
Mouse Rat
cellular response to lipopolysaccharide GO:0071222 77 0.214
Rat
defense response to bacterium GO:0042742 119 0.211
anatomical structure homeostasis GO:0060249 145 0.208
Mouse
regulation of establishment of protein localization GO:0070201 181 0.206
cellular amino acid metabolic process GO:0006520 103 0.205
immune response activating signal transduction GO:0002757 116 0.204
negative regulation of secretion GO:0051048 61 0.203
positive regulation of ion transport GO:0043270 65 0.203
positive regulation of angiogenesis GO:0045766 46 0.202
negative regulation of cellular protein metabolic process GO:0032269 247 0.202
cellular calcium ion homeostasis GO:0006874 119 0.202
response to organophosphorus GO:0046683 22 0.202
fibrinolysis GO:0042730 3 0.201
cellular ion homeostasis GO:0006873 165 0.201
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.199
membrane organization GO:0061024 245 0.198
antibacterial peptide secretion GO:0002779 1 0.194
negative regulation of cytokine production GO:0001818 84 0.193
regulation of secretion GO:0051046 274 0.193
cellular response to molecule of bacterial origin GO:0071219 83 0.191
Rat
antibacterial peptide biosynthetic process GO:0002780 2 0.190
amine metabolic process GO:0009308 45 0.190
regulation of hemostasis GO:1900046 28 0.189
skeletal system morphogenesis GO:0048705 203 0.187
negative regulation of proteolysis GO:0045861 74 0.184
response to organonitrogen compound GO:0010243 246 0.184
Rat
transmembrane transport GO:0055085 412 0.182
calcium ion transport into cytosol GO:0060402 48 0.182
reactive oxygen species metabolic process GO:0072593 84 0.181
Rat
positive regulation of protein kinase activity GO:0045860 144 0.180
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.178
regulation of morphogenesis of a branching structure GO:0060688 53 0.175
Mouse
regulation of protein localization GO:0032880 231 0.174
defense response to other organism GO:0098542 197 0.174
cell adhesion GO:0007155 329 0.168
Human
negative regulation of coagulation GO:0050819 11 0.165
t cell activation GO:0042110 289 0.163
kidney development GO:0001822 213 0.162
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.160
calcium ion homeostasis GO:0055074 127 0.159
negative regulation of protein modification process GO:0031400 163 0.159
lipid biosynthetic process GO:0008610 179 0.155
leukocyte mediated immunity GO:0002443 174 0.154
protein catabolic process GO:0030163 221 0.152
peptide metabolic process GO:0006518 46 0.149
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.147
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.147
vascular endothelial growth factor production GO:0010573 13 0.147
regulation of blood pressure GO:0008217 93 0.144
response to peptide hormone GO:0043434 127 0.144
immune response regulating signaling pathway GO:0002764 125 0.144
regulation of chemotaxis GO:0050920 53 0.142
muscle contraction GO:0006936 101 0.139
liver development GO:0001889 66 0.138
Mouse Rat
positive regulation of map kinase activity GO:0043406 84 0.138
Mouse
regulation of cellular response to stress GO:0080135 159 0.138
granulocyte migration GO:0097530 43 0.138
muscle cell cellular homeostasis GO:0046716 12 0.137
Mouse
regulation of vasculature development GO:1901342 88 0.135
regulation of cellular amine metabolic process GO:0033238 20 0.134
nitric oxide metabolic process GO:0046209 25 0.134
protein secretion GO:0009306 111 0.133
response to catecholamine GO:0071869 4 0.132
response to hypoxia GO:0001666 58 0.129
nucleobase containing small molecule metabolic process GO:0055086 352 0.129
response to purine containing compound GO:0014074 28 0.127
muscle system process GO:0003012 141 0.127
regulation of synaptic plasticity GO:0048167 87 0.126
immune effector process GO:0002252 321 0.126
positive regulation of protein phosphorylation GO:0001934 242 0.125
Mouse
fat cell differentiation GO:0045444 160 0.124
positive regulation of protein modification process GO:0031401 299 0.122
Mouse
multicellular organismal homeostasis GO:0048871 164 0.122
myotube differentiation GO:0014902 105 0.122
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.121
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.121
blood circulation GO:0008015 195 0.120
interleukin 10 secretion GO:0072608 4 0.120
positive regulation of response to wounding GO:1903036 66 0.120
tumor necrosis factor production GO:0032640 50 0.120
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.118
defense response to gram positive bacterium GO:0050830 50 0.117
cellular macromolecule catabolic process GO:0044265 206 0.117
g protein coupled receptor signaling pathway GO:0007186 243 0.117
regulation of kinase activity GO:0043549 249 0.116
Mouse
metal ion homeostasis GO:0055065 189 0.116
regulation of transmembrane transport GO:0034762 128 0.116
multicellular organism growth GO:0035264 161 0.115
antimicrobial peptide biosynthetic process GO:0002777 2 0.114
regulation of innate immune response GO:0045088 91 0.114
regulation of leukocyte proliferation GO:0070663 121 0.112
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling GO:0060665 5 0.111
Mouse
cellular ketone metabolic process GO:0042180 84 0.111
regulation of protein processing GO:0070613 96 0.111
regulation of metal ion transport GO:0010959 106 0.110
negative regulation of immune system process GO:0002683 209 0.106
positive regulation of synaptic plasticity GO:0031915 4 0.104
antimicrobial peptide production GO:0002775 2 0.104
regulation of tube size GO:0035150 57 0.102
purine containing compound catabolic process GO:0072523 213 0.102
macromolecule catabolic process GO:0009057 281 0.101
aromatic compound catabolic process GO:0019439 286 0.100
epithelium migration GO:0090132 63 0.100
extracellular structure organization GO:0043062 148 0.100
cellular response to hormone stimulus GO:0032870 150 0.100
ribonucleotide metabolic process GO:0009259 291 0.100
protein processing GO:0016485 163 0.099
tissue remodeling GO:0048771 102 0.098
positive regulation of nervous system development GO:0051962 221 0.097
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.096
protein maturation GO:0051604 176 0.096
prostaglandin metabolic process GO:0006693 11 0.095
cellular amide metabolic process GO:0043603 58 0.094
regulation of anatomical structure size GO:0090066 178 0.092
regulation of macrophage chemotaxis GO:0010758 8 0.091
digestive tract development GO:0048565 190 0.091
antibacterial peptide production GO:0002778 2 0.091
regulation of protein kinase b signaling GO:0051896 56 0.091
embryonic placenta development GO:0001892 98 0.091
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.090
response to steroid hormone GO:0048545 56 0.090
regulation of cytokine secretion GO:0050707 61 0.090
biomineral tissue development GO:0031214 64 0.090
regulation of protein secretion GO:0050708 82 0.089
organic anion transport GO:0015711 137 0.088
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.088
regulation of ion transmembrane transport GO:0034765 119 0.087
small molecule biosynthetic process GO:0044283 132 0.087
positive regulation of acute inflammatory response GO:0002675 16 0.087
second messenger mediated signaling GO:0019932 73 0.086
negative regulation of molecular function GO:0044092 258 0.085
regulation of interleukin 6 production GO:0032675 55 0.084
fibroblast growth factor production GO:0090269 4 0.084
negative regulation of wound healing GO:0061045 14 0.084
nitrogen compound transport GO:0071705 271 0.084
regulation of muscle system process GO:0090257 80 0.084
cellular protein catabolic process GO:0044257 155 0.083
regulation of cell migration GO:0030334 219 0.083
Human Rat
positive regulation of monocyte chemotaxis GO:0090026 2 0.083
vasoconstriction GO:0042310 27 0.082
production of molecular mediator of immune response GO:0002440 103 0.082
positive regulation of fat cell differentiation GO:0045600 32 0.082
connective tissue development GO:0061448 179 0.082
response to light stimulus GO:0009416 135 0.081
cellular response to growth factor stimulus GO:0071363 197 0.081
Rat
response to radiation GO:0009314 165 0.081
digestion GO:0007586 40 0.081
regulation of proteolysis GO:0030162 164 0.080
anion transport GO:0006820 177 0.080
regulation of blood circulation GO:1903522 93 0.079
developmental growth involved in morphogenesis GO:0060560 138 0.079
negative regulation of cell motility GO:2000146 61 0.079
regulation of cell motility GO:2000145 236 0.078
Human Rat
stem cell differentiation GO:0048863 268 0.078
organic acid transport GO:0015849 101 0.077
negative regulation of fat cell differentiation GO:0045599 36 0.076
positive regulation of apoptotic process GO:0043065 217 0.075
regulation of lymphocyte proliferation GO:0050670 117 0.075
positive regulation of innate immune response GO:0045089 80 0.073
cell chemotaxis GO:0060326 81 0.073
regulation of cell adhesion GO:0030155 154 0.072
Human
multicellular organismal signaling GO:0035637 91 0.072
digestive system development GO:0055123 200 0.071
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.071
organic hydroxy compound transport GO:0015850 93 0.070
cellular response to organic cyclic compound GO:0071407 87 0.070
Rat
cellular response to glucocorticoid stimulus GO:0071385 13 0.070
positive regulation of cellular amine metabolic process GO:0033240 5 0.070
cytoplasmic transport GO:0016482 234 0.070
protein modification by small protein conjugation or removal GO:0070647 207 0.070
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.070
branching morphogenesis of an epithelial tube GO:0048754 159 0.070
tissue regeneration GO:0042246 22 0.070
Mouse Rat
ovulation GO:0030728 15 0.069
Rat
i kappab kinase nf kappab signaling GO:0007249 85 0.069
renal system development GO:0072001 225 0.069
circulatory system process GO:0003013 197 0.069
axonogenesis GO:0007409 274 0.069
negative regulation of protein metabolic process GO:0051248 282 0.069
regulation of interleukin 12 production GO:0032655 30 0.067
positive regulation of proteolysis GO:0045862 85 0.067
negative regulation of cellular amine metabolic process GO:0033239 1 0.067
regulation of protein maturation GO:1903317 96 0.067
interspecies interaction between organisms GO:0044419 83 0.067
multicellular organismal metabolic process GO:0044236 28 0.067
glycosyl compound metabolic process GO:1901657 246 0.067
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.067
Mouse
alcohol metabolic process GO:0006066 116 0.066
cytosolic calcium ion transport GO:0060401 48 0.066
nucleoside metabolic process GO:0009116 246 0.066
regulation of vascular endothelial growth factor production GO:0010574 13 0.065
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.065
peptidyl amino acid modification GO:0018193 336 0.065
wnt signaling pathway GO:0016055 188 0.065
oligodendrocyte differentiation GO:0048709 53 0.065
muscle cell development GO:0055001 133 0.065
lipid transport GO:0006869 98 0.065
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.064
regulation of peptidase activity GO:0052547 96 0.063
t cell extravasation GO:0072683 4 0.063
protein kinase b signaling GO:0043491 74 0.063
negative regulation of protein maturation GO:1903318 79 0.063
carbohydrate derivative biosynthetic process GO:1901137 183 0.062
respiratory system development GO:0060541 190 0.062
epithelial cell development GO:0002064 159 0.062
modification dependent protein catabolic process GO:0019941 133 0.062
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.062
negative regulation of secretion by cell GO:1903531 54 0.062
lymphocyte proliferation GO:0046651 164 0.062
cellular metal ion homeostasis GO:0006875 151 0.062
plasma membrane organization GO:0007009 90 0.061
regulation of stress activated mapk cascade GO:0032872 69 0.061
protein oligomerization GO:0051259 67 0.061
appendage development GO:0048736 166 0.061
ubiquitin dependent protein catabolic process GO:0006511 129 0.061
regulation of neuron differentiation GO:0045664 281 0.060
negative regulation of muscle contraction GO:0045932 12 0.060
positive regulation vascular endothelial growth factor production GO:0010575 10 0.060
endocytosis GO:0006897 168 0.060
positive regulation of cytokine secretion GO:0050715 41 0.060
regulation of epithelial cell proliferation GO:0050678 141 0.059
Rat
peptidyl tyrosine modification GO:0018212 145 0.059
amide transport GO:0042886 138 0.059
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.059
cartilage development GO:0051216 140 0.059
ribonucleotide catabolic process GO:0009261 208 0.058
interleukin 6 production GO:0032635 58 0.058
sequestering of metal ion GO:0051238 19 0.057
neuron neuron synaptic transmission GO:0007270 69 0.057
endochondral bone morphogenesis GO:0060350 50 0.056
negative regulation of defense response GO:0031348 77 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.056
organonitrogen compound biosynthetic process GO:1901566 192 0.056
regulation of cellular catabolic process GO:0031329 242 0.056
transepithelial chloride transport GO:0030321 4 0.055
regulation of tumor necrosis factor production GO:0032680 49 0.055
response to dexamethasone GO:0071548 8 0.055
myeloid leukocyte migration GO:0097529 57 0.055
activation of immune response GO:0002253 138 0.055
regulation of coagulation GO:0050818 31 0.054
response to tumor necrosis factor GO:0034612 26 0.054
interleukin 12 production GO:0032615 32 0.054
regulation of angiogenesis GO:0045765 81 0.054
purine ribonucleoside metabolic process GO:0046128 241 0.054
development of primary female sexual characteristics GO:0046545 73 0.053
regulation of neurotransmitter levels GO:0001505 87 0.053
glial cell differentiation GO:0010001 131 0.053
positive regulation of cell motility GO:2000147 116 0.052
Rat
regulation of hormone levels GO:0010817 211 0.052
nucleotide catabolic process GO:0009166 217 0.052
response to peptidoglycan GO:0032494 9 0.052
leukocyte differentiation GO:0002521 342 0.051
positive regulation of cell migration GO:0030335 109 0.051
Rat
regulation of secretion by cell GO:1903530 249 0.051
positive regulation of homeostatic process GO:0032846 64 0.050
regulation of lymphocyte activation GO:0051249 240 0.050
endomembrane system organization GO:0010256 147 0.050
regulation of muscle contraction GO:0006937 49 0.049
heterocycle catabolic process GO:0046700 280 0.049
interleukin 5 secretion GO:0072603 2 0.049
peptidyl tyrosine phosphorylation GO:0018108 143 0.049
trabecula formation GO:0060343 24 0.049
long term synaptic potentiation GO:0060291 25 0.049
organic hydroxy compound biosynthetic process GO:1901617 77 0.049
regulation of adaptive immune response GO:0002819 90 0.049
regulation of wnt signaling pathway GO:0030111 123 0.049
negative regulation of macrophage apoptotic process GO:2000110 3 0.049
response to inorganic substance GO:0010035 96 0.048
neuron projection guidance GO:0097485 141 0.048
positive regulation of cell activation GO:0050867 158 0.048
cellular response to ketone GO:1901655 12 0.048
bone morphogenesis GO:0060349 78 0.048
hair cycle phase GO:0044851 16 0.048
cellular response to external stimulus GO:0071496 88 0.047
regulation of interleukin 13 secretion GO:2000665 2 0.047
regulation of blood vessel size GO:0050880 56 0.047
cytokine mediated signaling pathway GO:0019221 115 0.047
regulation of reproductive process GO:2000241 66 0.047
Rat
regulation of t cell proliferation GO:0042129 92 0.047
columnar cuboidal epithelial cell maturation GO:0002069 4 0.047
positive regulation of blood circulation GO:1903524 22 0.047
intracellular protein transport GO:0006886 204 0.047
interleukin 13 secretion GO:0072611 2 0.047
ceramide metabolic process GO:0006672 31 0.047
transmission of nerve impulse GO:0019226 76 0.047
striated muscle cell development GO:0055002 125 0.046
macrophage chemotaxis GO:0048246 14 0.046
regulation of vasoconstriction GO:0019229 14 0.046
regulation of homeostatic process GO:0032844 182 0.046
dna metabolic process GO:0006259 303 0.046
leukocyte activation involved in immune response GO:0002366 126 0.046
regulation of cell projection organization GO:0031344 206 0.046
epithelial cell proliferation GO:0050673 174 0.046
Rat
positive regulation of wnt signaling pathway GO:0030177 45 0.046
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.046
cation transmembrane transport GO:0098655 266 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.045
positive regulation of cell development GO:0010720 237 0.044
response to vitamin d GO:0033280 3 0.044
protein ubiquitination GO:0016567 171 0.044
regulation of blood coagulation GO:0030193 28 0.044
eosinophil degranulation GO:0043308 1 0.044
regulation of transporter activity GO:0032409 57 0.044
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.044
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.044
Rat
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.043
trabecula morphogenesis GO:0061383 40 0.043
epithelial tube morphogenesis GO:0060562 303 0.043
response to camp GO:0051591 14 0.043
nephron morphogenesis GO:0072028 69 0.043
forebrain development GO:0030900 302 0.043
positive regulation of protein transport GO:0051222 93 0.043
bone trabecula morphogenesis GO:0061430 12 0.043
regulation of monocyte extravasation GO:2000437 2 0.043
purine nucleotide metabolic process GO:0006163 302 0.042
regulation of wound healing GO:0061041 40 0.042
cardiac muscle tissue development GO:0048738 130 0.042
positive regulation of glial cell proliferation GO:0060252 4 0.041
positive regulation of interleukin 12 production GO:0032735 21 0.041
response to amine GO:0014075 16 0.041
negative regulation of ion transport GO:0043271 28 0.041
regulation of receptor binding GO:1900120 4 0.041
regulation of cytokine production involved in immune response GO:0002718 26 0.040
eosinophil activation involved in immune response GO:0002278 1 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
positive regulation of coagulation GO:0050820 13 0.040
striated muscle tissue development GO:0014706 293 0.040
muscle tissue development GO:0060537 308 0.040
leukocyte chemotaxis GO:0030595 69 0.039
urogenital system development GO:0001655 261 0.039
positive regulation of immunological synapse formation GO:2000522 1 0.039
negative regulation of inflammatory response GO:0050728 61 0.039
interleukin 1 beta production GO:0032611 30 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
modification dependent macromolecule catabolic process GO:0043632 133 0.039
regulation of steroid biosynthetic process GO:0050810 26 0.039
skeletal system development GO:0001501 356 0.038
regulation of alpha beta t cell activation GO:0046634 53 0.038
proteasomal protein catabolic process GO:0010498 98 0.038
sensory perception of pain GO:0019233 47 0.038
labyrinthine layer blood vessel development GO:0060716 21 0.038
Mouse
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.038
cytokine metabolic process GO:0042107 71 0.038
regulation of tissue remodeling GO:0034103 38 0.038
regulation of systemic arterial blood pressure GO:0003073 61 0.037
negative regulation of phosphorylation GO:0042326 166 0.037
nucleotide metabolic process GO:0009117 332 0.037
amino acid transmembrane transport GO:0003333 37 0.037
positive regulation of leukocyte proliferation GO:0070665 73 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.037
organelle localization GO:0051640 179 0.037
lung development GO:0030324 164 0.037
negative regulation of cell adhesion GO:0007162 45 0.037
carboxylic acid transport GO:0046942 100 0.037
regulation of intracellular transport GO:0032386 159 0.037
sensory perception GO:0007600 245 0.037
jnk cascade GO:0007254 72 0.036
metanephros development GO:0001656 79 0.036
nuclear transport GO:0051169 139 0.036
negative regulation of hemostasis GO:1900047 11 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
serotonin transport GO:0006837 11 0.036
response to growth factor GO:0070848 198 0.036
Rat
gliogenesis GO:0042063 141 0.036
positive regulation of muscle contraction GO:0045933 10 0.036
positive regulation of chemotaxis GO:0050921 38 0.035
bone development GO:0060348 120 0.035
cellular response to steroid hormone stimulus GO:0071383 33 0.035
regulation of oxidoreductase activity GO:0051341 15 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.035
regulation of lipid biosynthetic process GO:0046890 54 0.035
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.034
superoxide metabolic process GO:0006801 27 0.034
regulation of gliogenesis GO:0014013 50 0.034
protein targeting GO:0006605 143 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
interaction with host GO:0051701 22 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
protein modification by small protein conjugation GO:0032446 187 0.034
eye photoreceptor cell differentiation GO:0001754 41 0.034
positive regulation of lymphocyte proliferation GO:0050671 70 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
defense response to gram negative bacterium GO:0050829 28 0.033
regulation of cysteine type endopeptidase activity GO:2000116 65 0.033
negative regulation of apoptotic signaling pathway GO:2001234 104 0.033
Mouse
synaptic transmission glutamatergic GO:0035249 36 0.033
regulation of calcium ion transport GO:0051924 69 0.033
organic acid biosynthetic process GO:0016053 86 0.033
response to corticosteroid GO:0031960 20 0.033
response to alcohol GO:0097305 48 0.033
multicellular organismal catabolic process GO:0044243 7 0.033
epithelial cell migration GO:0010631 63 0.032
alpha amino acid catabolic process GO:1901606 18 0.032
single organism nuclear import GO:1902593 95 0.032
positive regulation of brown fat cell differentiation GO:0090336 4 0.032
oxidation reduction process GO:0055114 342 0.032
fatty acid derivative biosynthetic process GO:1901570 15 0.032
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.032
vascular process in circulatory system GO:0003018 62 0.032
positive regulation of lipid transport GO:0032370 22 0.032
modification by symbiont of host morphology or physiology GO:0044003 4 0.032
regulation of organelle organization GO:0033043 289 0.032

Plau disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.059
inherited metabolic disorder DOID:655 0 0.032