IMP

Process View

Mus musculus

4 genes annotated in mouse

columnar cuboidal epithelial cell maturation

GO:0002069

The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "columnar cuboidal epithelial cell maturation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "columnar cuboidal epithelial cell maturation" (in gray)

Name	Description	Probability	Func Analog Organism
Hoxc5	homeobox C5	0.999	Mouse
Hoxb5	homeobox B5	0.999	Mouse
Hoxb3	homeobox B3	0.990
Hoxa5	homeobox A5	0.987
Hoxb6	homeobox B6	0.987	Mouse
Hoxb4	homeobox B4	0.986	Mouse
Hoxc4	homeobox C4	0.984	Mouse
Hoxa9	homeobox A9	0.978
Hoxa2	homeobox A2	0.977
Hoxd9	homeobox D9	0.977
Hoxd3	homeobox D3	0.965
Hoxa10	homeobox A10	0.958
Hoxc8	homeobox C8	0.946	Mouse
Hoxd8	homeobox D8	0.941	Mouse
Hoxc6	homeobox C6	0.916	Mouse
Hoxb2	homeobox B2	0.863
Hoxa4	homeobox A4	0.831	Mouse
Hoxd10	homeobox D10	0.812
Pbx1	pre B-cell leukemia transcription factor 1	0.744
Hoxa11	homeobox A11	0.730
Hoxb9	homeobox B9	0.722
Hoxc9	homeobox C9	0.712
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.644
Hoxb8	homeobox B8	0.601	Mouse
Hoxd4	homeobox D4	0.601	Mouse
Hoxa7	homeobox A7	0.556	Mouse
Sim1	single-minded homolog 1 (Drosophila)	0.539	Mouse
Wt1	Wilms tumor 1 homolog	0.444
Hoxa3	homeobox A3	0.412
Bnc1	basonuclin 1	0.393
Meis1	Meis homeobox 1	0.330
Gdnf	glial cell line derived neurotrophic factor	0.284
Hoxa1	homeobox A1	0.269
Hoxd11	homeobox D11	0.262
Foxd2	forkhead box D2	0.241
Sox7	SRY-box containing gene 7	0.229
Egln1	EGL nine homolog 1 (C. elegans)	0.200
Ebf3	early B-cell factor 3	0.199
Sall3	sal-like 3 (Drosophila)	0.198
Gpr50	G-protein-coupled receptor 50	0.172
Vhl	von Hippel-Lindau tumor suppressor	0.171
Foxd1	forkhead box D1	0.170
Twist2	twist homolog 2 (Drosophila)	0.142
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.128
Sim2	single-minded homolog 2 (Drosophila)	0.121	Mouse
Gata2	GATA binding protein 2	0.119
Dlk1	delta-like 1 homolog (Drosophila)	0.104
Upk3b	uroplakin 3B	0.101
Zfp185	zinc finger protein 185	0.086
Zfp503	zinc finger protein 503	0.084
Ctf1	cardiotrophin 1	0.077
Wnt6	wingless-related MMTV integration site 6	0.072
She	src homology 2 domain-containing transforming protein E	0.071
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.067
Myog	myogenin	0.065
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.064
Efna2	ephrin A2	0.062
Greb1	gene regulated by estrogen in breast cancer protein	0.061
Gm13290	predicted gene 13290	0.060
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.060
Hoxc10	homeobox C10	0.059
Shox2	short stature homeobox 2	0.058
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.056
Foxa2	forkhead box A2	0.054
Hoxb1	homeobox B1	0.049
Myod1	myogenic differentiation 1	0.049
Lhx1	LIM homeobox protein 1	0.047
Tcf21	transcription factor 21	0.047
Plau	plasminogen activator, urokinase	0.047
Tcf15	transcription factor 15	0.047
Rdh10	retinol dehydrogenase 10 (all-trans)	0.046
Foxf1a	forkhead box F1a	0.044
Wnt2b	wingless related MMTV integration site 2b	0.044
Tbx15	T-box 15	0.042
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.041
Wnt1	wingless-related MMTV integration site 1	0.041
Uncx	UNC homeobox	0.040
Hoxa6	homeobox A6	0.040	Mouse
Bcl2	B-cell leukemia/lymphoma 2	0.040
Hbb-b1	hemoglobin, beta adult major chain	0.040
Actn3	actinin alpha 3	0.039
Tgfbr3	transforming growth factor, beta receptor III	0.038
Ihh	Indian hedgehog	0.038
Pax8	paired box gene 8	0.037
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.036
Emid2	EMI domain containing 2	0.036
Tnp2	transition protein 2	0.036
Adra2b	adrenergic receptor, alpha 2b	0.036
Nynrin	NYN domain and retroviral integrase containing	0.035
C1qtnf3	C1q and tumor necrosis factor related protein 3	0.034
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.034
Ank1	ankyrin 1, erythroid	0.032
Dhh	desert hedgehog	0.031
Lef1	lymphoid enhancer binding factor 1	0.031
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.031
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.030
Cdh16	cadherin 16	0.029
Tead3	TEA domain family member 3	0.029
Tbx2	T-box 2	0.029
Aqp7	aquaporin 7	0.028
Zic1	zinc finger protein of the cerebellum 1	0.028
Sult5a1	sulfotransferase family 5A, member 1	0.028
Msi1	Musashi homolog 1(Drosophila)	0.028
Hoxb7	homeobox B7	0.027	Mouse
Pbx3	pre B-cell leukemia transcription factor 3	0.027
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.026
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.026
Clcnka	chloride channel Ka	0.026
Epor	erythropoietin receptor	0.026
Edn3	endothelin 3	0.026
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.026
Nkx6-1	NK6 homeobox 1	0.025
Ggnbp1	gametogenetin binding protein 1	0.025
Fgf8	fibroblast growth factor 8	0.025
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.025
Sh3pxd2a	SH3 and PX domains 2A	0.025
Gli1	GLI-Kruppel family member GLI1	0.024
Stc2	stanniocalcin 2	0.024
Sox3	SRY-box containing gene 3	0.023
Pitx1	paired-like homeodomain transcription factor 1	0.023
Tsga10	testis specific 10	0.023
Hmga2	high mobility group AT-hook 2	0.022
Fgf4	fibroblast growth factor 4	0.022
Arnt	aryl hydrocarbon receptor nuclear translocator	0.022
Lhx9	LIM homeobox protein 9	0.021
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.021
Cdh3	cadherin 3	0.021
En1	engrailed 1	0.021
Fzd4	frizzled homolog 4 (Drosophila)	0.021
Egln3	EGL nine homolog 3 (C. elegans)	0.021
Wasf1	WASP family 1	0.020
Rictor	RPTOR independent companion of MTOR, complex 2	0.020
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.020
Cldn8	claudin 8	0.019
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.019
AI448005	expressed sequence AI448005	0.019
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.019
Pthlh	parathyroid hormone-like peptide	0.019
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.019
Zfp57	zinc finger protein 57	0.019
Tnni1	troponin I, skeletal, slow 1	0.019
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.018
Hoxa13	homeobox A13	0.018
Pou3f3	POU domain, class 3, transcription factor 3	0.018
Casq1	calsequestrin 1	0.018
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.018
Irx3	Iroquois related homeobox 3 (Drosophila)	0.018
Hes2	hairy and enhancer of split 2 (Drosophila)	0.018
Dmpk	dystrophia myotonica-protein kinase	0.018
Mab21l2	mab-21-like 2 (C. elegans)	0.017
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.017
Plac1	placental specific protein 1	0.017
Phlda2	pleckstrin homology-like domain, family A, member 2	0.016
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.016
Hoxc11	homeobox C11	0.016
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.016
Lrp2	low density lipoprotein receptor-related protein 2	0.016
Aplnr	apelin receptor	0.016
Tbx3	T-box 3	0.016
Fzd8	frizzled homolog 8 (Drosophila)	0.016
Col4a4	collagen, type IV, alpha 4	0.016
Ptpru	protein tyrosine phosphatase, receptor type, U	0.016
Myoz1	myozenin 1	0.015
Rgnef	Rho-guanine nucleotide exchange factor	0.015
Gata6	GATA binding protein 6	0.015
Tcfap2c	transcription factor AP-2, gamma	0.015
Wnt11	wingless-related MMTV integration site 11	0.015
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.015
Meis2	Meis homeobox 2	0.015
Fitm1	fat storage-inducing transmembrane protein 1	0.015
Prph	peripherin	0.015
Efna5	ephrin A5	0.015
Des	desmin	0.015
Fgfr2	fibroblast growth factor receptor 2	0.014
Sox13	SRY-box containing gene 13	0.014
Car12	carbonic anyhydrase 12	0.014
Wnt5b	wingless-related MMTV integration site 5B	0.014
Neurog1	neurogenin 1	0.014
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.014
Ncoa2	nuclear receptor coactivator 2	0.014
Tcfap2a	transcription factor AP-2, alpha	0.014
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.014
Sox17	SRY-box containing gene 17	0.014
Pou3f1	POU domain, class 3, transcription factor 1	0.014
Lepr	leptin receptor	0.014
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.013
Mdfi	MyoD family inhibitor	0.013
Msx1	homeobox, msh-like 1	0.013
Nrtn	neurturin	0.013
Efnb1	ephrin B1	0.013
Tsc22d3	TSC22 domain family, member 3	0.013
Alx3	aristaless-like homeobox 3	0.013
Ptch2	patched homolog 2	0.013
Scx	scleraxis	0.013
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.013
Cdh6	cadherin 6	0.013
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.013
Col4a3	collagen, type IV, alpha 3	0.013
Npr1	natriuretic peptide receptor 1	0.013
Pou3f2	POU domain, class 3, transcription factor 2	0.013
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.012
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.012
Foxo4	forkhead box O4	0.012
Grem1	gremlin 1	0.012
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.012
Shisa3	shisa homolog 3 (Xenopus laevis)	0.012
Mecom	MDS1 and EVI1 complex locus	0.012
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.012
Tert	telomerase reverse transcriptase	0.012
Sytl4	synaptotagmin-like 4	0.012
Glra1	glycine receptor, alpha 1 subunit	0.012
Cldn11	claudin 11	0.012
Stc1	stanniocalcin 1	0.012
Foxo1	forkhead box O1	0.012
Otp	orthopedia homolog (Drosophila)	0.012
Nrk	Nik related kinase	0.012
Vgll2	vestigial like 2 homolog (Drosophila)	0.012
Prx	periaxin	0.012
Hoxd1	homeobox D1	0.012
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.011
Axin2	axin2	0.011
Shh	sonic hedgehog	0.011
Msx2	homeobox, msh-like 2	0.011
Dmtf1	cyclin D binding myb-like transcription factor 1	0.011
Pou5f1	POU domain, class 5, transcription factor 1	0.011
Rax	retina and anterior neural fold homeobox	0.011
Cubn	cubilin (intrinsic factor-cobalamin receptor)	0.011
Nhlh1	nescient helix loop helix 1	0.011
Ptrf	polymerase I and transcript release factor	0.011
Slc38a5	solute carrier family 38, member 5	0.011
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.011
Fxyd2	FXYD domain-containing ion transport regulator 2	0.011
Ctnna2	catenin (cadherin associated protein), alpha 2	0.011
Tmem116	transmembrane protein 116	0.011
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.010
Zim1	zinc finger, imprinted 1	0.010
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.010
Emid1	EMI domain containing 1	0.010
Col7a1	collagen, type VII, alpha 1	0.010
Rhcg	Rhesus blood group-associated C glycoprotein	0.010
Cckar	cholecystokinin A receptor	0.010
Mll2	myeloid/lymphoid or mixed-lineage leukemia 2	0.010
Ar	androgen receptor	0.010
Dach1	dachshund 1 (Drosophila)	0.010
BC020535	cDNA sequence BC020535	0.010
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.010
Epo	erythropoietin	0.010