Mus musculus

191 known processes

Pmaip1

phorbol-12-myristate-13-acetate-induced protein 1

(Aliases: Noxa)

Pmaip1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.943
cellular response to gamma radiation GO:0071480 4 0.873
protein insertion into mitochondrial membrane GO:0051204 4 0.802
release of cytochrome c from mitochondria GO:0001836 23 0.797
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.552
mitochondrial membrane organization GO:0007006 26 0.545
regulation of pigment cell differentiation GO:0050932 7 0.498
apoptotic mitochondrial changes GO:0008637 48 0.492
regulation of mitochondrion organization GO:0010821 27 0.451
spermatogenesis GO:0007283 284 0.410
mitochondrial outer membrane permeabilization GO:0097345 10 0.398
regulation of nucleoside metabolic process GO:0009118 130 0.388
regulation of mitochondrial membrane potential GO:0051881 17 0.364
fertilization GO:0009566 127 0.363
mitochondrial fusion GO:0008053 9 0.361
sequestering of calcium ion GO:0051208 18 0.360
establishment of protein localization to mitochondrion GO:0072655 11 0.356
cytosolic calcium ion transport GO:0060401 48 0.354
positive regulation of cellular catabolic process GO:0031331 148 0.346
regulation of melanocyte differentiation GO:0045634 7 0.345
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.343
lymphocyte homeostasis GO:0002260 64 0.335
positive regulation of mitochondrion organization GO:0010822 17 0.320
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.319
response to endoplasmic reticulum stress GO:0034976 53 0.298
regulation of hydrolase activity GO:0051336 246 0.296
regulation of purine nucleotide metabolic process GO:1900542 169 0.294
positive regulation of mitochondrial membrane permeability GO:0035794 12 0.283
purine nucleotide catabolic process GO:0006195 211 0.283
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.277
positive regulation of cellular amine metabolic process GO:0033240 5 0.270
negative regulation of retinal cell programmed cell death GO:0046671 2 0.268
sphingolipid metabolic process GO:0006665 45 0.263
organelle fusion GO:0048284 28 0.261
positive regulation of neuron apoptotic process GO:0043525 25 0.259
ribonucleotide catabolic process GO:0009261 208 0.259
sequestering of metal ion GO:0051238 19 0.258
regulation of mitochondrial membrane permeability GO:0046902 17 0.257
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.256
Human
germ cell development GO:0007281 185 0.256
dephosphorylation GO:0016311 129 0.254
actin cytoskeleton organization GO:0030036 220 0.254
positive regulation of smooth muscle cell migration GO:0014911 4 0.251
apoptotic process involved in mammary gland involution GO:0060057 4 0.248
positive regulation of skeletal muscle fiber development GO:0048743 3 0.236
spermatid differentiation GO:0048515 115 0.235
glycoprotein biosynthetic process GO:0009101 89 0.235
regulation of cellular amino acid metabolic process GO:0006521 5 0.235
signal transduction by p53 class mediator GO:0072331 51 0.233
regulation of membrane potential GO:0042391 192 0.233
cellular amino acid metabolic process GO:0006520 103 0.229
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 14 0.229
purine nucleoside catabolic process GO:0006152 205 0.229
regulation of ion transport GO:0043269 215 0.229
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.227
Human
regulation of cellular amine metabolic process GO:0033238 20 0.225
guanosine containing compound metabolic process GO:1901068 144 0.225
purine nucleotide metabolic process GO:0006163 302 0.223
vesicle organization GO:0016050 60 0.223
cellular lipid metabolic process GO:0044255 323 0.221
positive regulation of gtpase activity GO:0043547 85 0.220
nucleoside catabolic process GO:0009164 206 0.219
aromatic compound catabolic process GO:0019439 286 0.217
extrinsic apoptotic signaling pathway GO:0097191 126 0.217
Human
regulation of gtp catabolic process GO:0033124 113 0.217
response to radiation GO:0009314 165 0.216
amine metabolic process GO:0009308 45 0.216
peptidyl serine phosphorylation GO:0018105 74 0.215
cellular response to starvation GO:0009267 57 0.215
Human
gtp metabolic process GO:0046039 144 0.214
purine ribonucleoside metabolic process GO:0046128 241 0.212
calcium ion transport GO:0006816 159 0.208
cellular response to amino acid stimulus GO:0071230 29 0.208
t cell homeostatic proliferation GO:0001777 4 0.207
nucleoside triphosphate metabolic process GO:0009141 230 0.207
membrane fusion GO:0061025 38 0.206
cellular metal ion homeostasis GO:0006875 151 0.205
regulation of cellular ketone metabolic process GO:0010565 66 0.205
urogenital system development GO:0001655 261 0.204
cation transport GO:0006812 399 0.203
regulation of ion homeostasis GO:2000021 64 0.203
nucleotide metabolic process GO:0009117 332 0.202
purine containing compound catabolic process GO:0072523 213 0.202
protein localization to membrane GO:0072657 108 0.201
positive regulation of hydrolase activity GO:0051345 148 0.200
activation of cysteine type endopeptidase activity GO:0097202 27 0.199
positive regulation of mammary gland involution GO:1903521 4 0.198
embryonic limb morphogenesis GO:0030326 126 0.195
negative regulation of cellular amine metabolic process GO:0033239 1 0.194
mitochondrial transport GO:0006839 36 0.194
cochlear nucleus development GO:0021747 4 0.192
purine ribonucleotide metabolic process GO:0009150 290 0.190
cellular amine metabolic process GO:0044106 44 0.189
purine ribonucleoside catabolic process GO:0046130 205 0.189
regulation of cellular catabolic process GO:0031329 242 0.188
negative regulation of b cell apoptotic process GO:0002903 7 0.188
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.187
positive regulation of nucleotide catabolic process GO:0030813 88 0.187
leukocyte homeostasis GO:0001776 79 0.186
carbohydrate derivative biosynthetic process GO:1901137 183 0.186
necrotic cell death GO:0070265 30 0.184
negative regulation of homeostatic process GO:0032845 71 0.184
negative regulation of cell cycle GO:0045786 123 0.184
establishment of protein localization to membrane GO:0090150 54 0.183
positive regulation of nucleoside metabolic process GO:0045979 91 0.183
liposaccharide metabolic process GO:1903509 27 0.183
negative regulation of calcium ion transport into cytosol GO:0010523 2 0.182
purine nucleoside metabolic process GO:0042278 241 0.181
nucleotide catabolic process GO:0009166 217 0.181
response to amino acid GO:0043200 37 0.181
ribonucleoside catabolic process GO:0042454 206 0.180
regulation of mammary gland involution GO:1903519 4 0.180
regulation of nucleotide metabolic process GO:0006140 169 0.180
ribonucleoside triphosphate catabolic process GO:0009203 199 0.180
regulation of cell cycle GO:0051726 281 0.180
glycosyl compound catabolic process GO:1901658 206 0.180
guanosine containing compound catabolic process GO:1901069 144 0.179
apoptotic signaling pathway GO:0097190 306 0.179
regulation of neuron death GO:1901214 134 0.177
mitochondrion organization GO:0007005 134 0.177
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.176
Human
female gonad development GO:0008585 71 0.175
cellular response to oxidative stress GO:0034599 76 0.175
gtp catabolic process GO:0006184 143 0.175
nucleoside phosphate metabolic process GO:0006753 338 0.173
nucleobase containing small molecule metabolic process GO:0055086 352 0.172
zymogen activation GO:0031638 41 0.172
nucleoside triphosphate catabolic process GO:0009143 205 0.170
organophosphate catabolic process GO:0046434 232 0.170
cellular ketone metabolic process GO:0042180 84 0.169
cellular nitrogen compound catabolic process GO:0044270 280 0.169
regulation of calcium ion transport into cytosol GO:0010522 31 0.169
cell aging GO:0007569 35 0.167
intrinsic apoptotic signaling pathway GO:0097193 132 0.167
nucleoside phosphate catabolic process GO:1901292 222 0.166
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.166
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.166
hepatocyte apoptotic process GO:0097284 11 0.164
positive regulation of gtp catabolic process GO:0033126 85 0.164
purine nucleoside triphosphate metabolic process GO:0009144 226 0.162
mesonephric epithelium development GO:0072163 94 0.162
reactive oxygen species metabolic process GO:0072593 84 0.161
Human
regulation of nucleotide catabolic process GO:0030811 122 0.160
cation homeostasis GO:0055080 212 0.160
t cell homeostasis GO:0043029 35 0.160
negative regulation of osteoblast proliferation GO:0033689 4 0.160
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 4 0.160
renal system process GO:0003014 48 0.159
cellular response to light stimulus GO:0071482 19 0.158
purine ribonucleotide catabolic process GO:0009154 208 0.158
ribose phosphate metabolic process GO:0019693 291 0.157
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.157
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.156
cell adhesion GO:0007155 329 0.156
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.156
organic cyclic compound catabolic process GO:1901361 295 0.154
metal ion homeostasis GO:0055065 189 0.154
embryonic appendage morphogenesis GO:0035113 126 0.152
kidney development GO:0001822 213 0.152
cerebral cortex development GO:0021987 86 0.151
ribonucleoside metabolic process GO:0009119 245 0.151
regulation of neuron apoptotic process GO:0043523 122 0.151
ovarian follicle development GO:0001541 40 0.151
renal tubule morphogenesis GO:0061333 72 0.147
divalent metal ion transport GO:0070838 172 0.147
forebrain development GO:0030900 302 0.146
actin filament organization GO:0007015 113 0.146
regulation of neuron differentiation GO:0045664 281 0.145
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.144
negative regulation of phosphate metabolic process GO:0045936 184 0.143
response to light stimulus GO:0009416 135 0.143
muscle cell differentiation GO:0042692 261 0.143
ribonucleoside triphosphate metabolic process GO:0009199 220 0.143
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.142
regulation of homeostatic process GO:0032844 182 0.142
skeletal muscle fiber development GO:0048741 58 0.141
membrane lipid metabolic process GO:0006643 53 0.141
protein oligomerization GO:0051259 67 0.140
Human
response to osmotic stress GO:0006970 21 0.140
muscle cell development GO:0055001 133 0.140
positive regulation of apoptotic signaling pathway GO:2001235 95 0.139
purine nucleoside triphosphate catabolic process GO:0009146 203 0.138
nucleoside metabolic process GO:0009116 246 0.138
glycolipid metabolic process GO:0006664 25 0.137
pigment metabolic process GO:0042440 32 0.137
viral process GO:0016032 41 0.136
metencephalon development GO:0022037 89 0.135
positive regulation of striated muscle cell differentiation GO:0051155 35 0.135
positive regulation of endopeptidase activity GO:0010950 43 0.135
cellular chemical homeostasis GO:0055082 215 0.135
positive regulation of neuron death GO:1901216 28 0.135
appendage morphogenesis GO:0035107 149 0.135
membrane organization GO:0061024 245 0.135
regulation of fibroblast proliferation GO:0048145 34 0.134
regulation of cell motility GO:2000145 236 0.134
blood vessel remodeling GO:0001974 33 0.132
cellular homeostasis GO:0019725 240 0.132
limb development GO:0060173 166 0.132
negative regulation of cell proliferation GO:0008285 296 0.132
cell junction organization GO:0034330 77 0.131
ribonucleotide metabolic process GO:0009259 291 0.131
odontogenesis GO:0042476 78 0.131
renal system development GO:0072001 225 0.130
fibroblast proliferation GO:0048144 35 0.129
regulation of organelle organization GO:0033043 289 0.129
regulation of b cell apoptotic process GO:0002902 13 0.129
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.128
epithelial tube morphogenesis GO:0060562 303 0.128
kidney morphogenesis GO:0060993 83 0.128
pigment cell differentiation GO:0050931 27 0.127
morphogenesis of a branching structure GO:0001763 203 0.127
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.127
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 3 0.126
regulation of intracellular transport GO:0032386 159 0.126
negative regulation of mitotic cell cycle GO:0045930 58 0.126
heterocycle catabolic process GO:0046700 280 0.125
positive regulation of peptidase activity GO:0010952 49 0.125
regulation of apoptotic signaling pathway GO:2001233 197 0.124
positive regulation of nucleotide metabolic process GO:0045981 114 0.124
viral genome replication GO:0019079 17 0.124
response to gamma radiation GO:0010332 22 0.124
cell substrate adhesion GO:0031589 130 0.123
release of sequestered calcium ion into cytosol GO:0051209 42 0.123
cellular response to extracellular stimulus GO:0031668 81 0.123
Human
adherens junction assembly GO:0034333 22 0.123
response to acid chemical GO:0001101 111 0.122
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.121
positive regulation of nervous system development GO:0051962 221 0.121
regulation of metal ion transport GO:0010959 106 0.121
negative regulation of phosphorylation GO:0042326 166 0.121
regulation of developmental pigmentation GO:0048070 14 0.121
cellular ion homeostasis GO:0006873 165 0.120
divalent inorganic cation transport GO:0072511 178 0.119
cytosolic calcium ion homeostasis GO:0051480 70 0.119
organic hydroxy compound metabolic process GO:1901615 203 0.119
cytoplasmic transport GO:0016482 234 0.118
b cell apoptotic process GO:0001783 19 0.118
cellular calcium ion homeostasis GO:0006874 119 0.117
negative regulation of cellular protein metabolic process GO:0032269 247 0.117
mitotic cell cycle GO:0000278 195 0.117
cellular response to acid chemical GO:0071229 68 0.116
stem cell differentiation GO:0048863 268 0.116
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.116
ectopic germ cell programmed cell death GO:0035234 9 0.114
negative regulation of hydrolase activity GO:0051346 71 0.114
response to decreased oxygen levels GO:0036293 59 0.114
Human
cellular divalent inorganic cation homeostasis GO:0072503 127 0.114
rhythmic process GO:0048511 174 0.114
organ growth GO:0035265 117 0.113
b cell differentiation GO:0030183 78 0.113
neuroepithelial cell differentiation GO:0060563 37 0.113
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.113
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.112
multicellular organismal response to stress GO:0033555 62 0.111
positive regulation of homeostatic process GO:0032846 64 0.111
sensory organ morphogenesis GO:0090596 242 0.111
negative regulation of growth GO:0045926 99 0.110
leukocyte apoptotic process GO:0071887 71 0.110
nuclear division GO:0000280 158 0.109
positive regulation of cell development GO:0010720 237 0.108
multicellular organismal homeostasis GO:0048871 164 0.108
homeostasis of number of cells GO:0048872 210 0.107
ureteric bud development GO:0001657 94 0.106
development of primary male sexual characteristics GO:0046546 88 0.106
regulation of skeletal muscle fiber development GO:0048742 36 0.105
positive regulation of organelle organization GO:0010638 128 0.105
negative regulation of molecular function GO:0044092 258 0.104
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.104
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.104
regulation of peptidyl serine phosphorylation GO:0033135 39 0.102
regulation of cell substrate adhesion GO:0010810 73 0.101
glycosyl compound metabolic process GO:1901657 246 0.101
limb morphogenesis GO:0035108 149 0.101
positive regulation of cell death GO:0010942 224 0.101
negative regulation of protein modification process GO:0031400 163 0.100
mesonephros development GO:0001823 97 0.100
t cell proliferation GO:0042098 120 0.099
mitotic cell cycle process GO:1903047 159 0.099
peptidyl amino acid modification GO:0018193 336 0.099
ear development GO:0043583 200 0.099
negative regulation of neuron death GO:1901215 98 0.098
b cell proliferation GO:0042100 53 0.098
regulation of leukocyte apoptotic process GO:2000106 56 0.097
divalent inorganic cation homeostasis GO:0072507 138 0.097
neuron apoptotic process GO:0051402 142 0.097
b cell homeostasis GO:0001782 34 0.096
interspecies interaction between organisms GO:0044419 83 0.096
regulation of muscle tissue development GO:1901861 97 0.096
carbohydrate derivative catabolic process GO:1901136 231 0.096
positive regulation of muscle tissue development GO:1901863 32 0.095
positive regulation of programmed cell death GO:0043068 218 0.094
striated muscle cell development GO:0055002 125 0.094
protein maturation GO:0051604 176 0.093
programmed necrotic cell death GO:0097300 28 0.093
organelle fission GO:0048285 170 0.093
muscle fiber development GO:0048747 76 0.093
pallium development GO:0021543 120 0.093
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.093
cell division GO:0051301 120 0.092
negative regulation of apoptotic signaling pathway GO:2001234 104 0.092
nephron tubule development GO:0072080 84 0.092
regulation of mitotic cell cycle GO:0007346 126 0.091
t cell differentiation in thymus GO:0033077 77 0.091
positive regulation of cell maturation GO:1903431 4 0.091
regulation of calcium ion transport GO:0051924 69 0.091
myotube differentiation GO:0014902 105 0.091
striated muscle tissue development GO:0014706 293 0.090
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.090
mesenchyme development GO:0060485 152 0.090
cellular pigmentation GO:0033059 20 0.090
regulation of cellular response to stress GO:0080135 159 0.090
female sex differentiation GO:0046660 84 0.089
peptidyl serine modification GO:0018209 83 0.089
regulation of cytoplasmic transport GO:1903649 112 0.089
ossification GO:0001503 216 0.089
cell fate commitment GO:0045165 210 0.089
signal transduction in absence of ligand GO:0038034 55 0.088
regulation of cellular response to oxidative stress GO:1900407 19 0.088
skeletal muscle organ development GO:0060538 163 0.088
melanocyte differentiation GO:0030318 25 0.088
protein localization to organelle GO:0033365 185 0.088
blood vessel morphogenesis GO:0048514 285 0.088
posttranscriptional regulation of gene expression GO:0010608 155 0.087
response to extracellular stimulus GO:0009991 127 0.087
Human
development of primary female sexual characteristics GO:0046545 73 0.087
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.087
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.087
embryonic digit morphogenesis GO:0042733 56 0.086
cell cycle g1 s phase transition GO:0044843 57 0.086
cell cell junction organization GO:0045216 72 0.086
response to organonitrogen compound GO:0010243 246 0.086
negative regulation of nuclear division GO:0051784 19 0.086
hindbrain development GO:0030902 128 0.085
epidermis morphogenesis GO:0048730 33 0.084
regulation of protein maturation GO:1903317 96 0.084
peptidyl threonine modification GO:0018210 31 0.084
positive regulation of calcium ion transport GO:0051928 27 0.084
fear response GO:0042596 33 0.084
viral life cycle GO:0019058 36 0.084
positive regulation of pigment cell differentiation GO:0050942 5 0.083
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.083
pigmentation GO:0043473 71 0.083
male gamete generation GO:0048232 285 0.083
metanephros development GO:0001656 79 0.083
myeloid cell apoptotic process GO:0033028 22 0.083
ovulation cycle GO:0042698 59 0.082
g1 s transition of mitotic cell cycle GO:0000082 57 0.082
positive regulation of neuron differentiation GO:0045666 141 0.082
kidney epithelium development GO:0072073 121 0.082
regulation of tissue remodeling GO:0034103 38 0.081
nephron epithelium morphogenesis GO:0072088 68 0.081
mesonephric tubule development GO:0072164 94 0.081
response to oxygen levels GO:0070482 62 0.081
Human
cell junction assembly GO:0034329 52 0.081
male sex differentiation GO:0046661 109 0.080
skin development GO:0043588 220 0.079
t cell apoptotic process GO:0070231 39 0.079
branching involved in ureteric bud morphogenesis GO:0001658 56 0.079
maintenance of location GO:0051235 89 0.079
single organismal cell cell adhesion GO:0016337 131 0.078
peptidyl threonine phosphorylation GO:0018107 31 0.078
establishment of protein localization to organelle GO:0072594 118 0.078
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.077
mammary gland involution GO:0060056 9 0.077
regulation of cell adhesion GO:0030155 154 0.077
leukocyte differentiation GO:0002521 342 0.077
muscle tissue development GO:0060537 308 0.077
developmental pigmentation GO:0048066 40 0.077
regulation of lymphocyte apoptotic process GO:0070228 41 0.076
t cell activation GO:0042110 289 0.076
secondary metabolic process GO:0019748 18 0.076
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.076
thymocyte apoptotic process GO:0070242 19 0.076
anatomical structure homeostasis GO:0060249 145 0.076
cellular response to radiation GO:0071478 28 0.076
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.075
response to steroid hormone GO:0048545 56 0.075
hair cycle GO:0042633 90 0.075
axonogenesis GO:0007409 274 0.075
angiogenesis GO:0001525 201 0.075
regulation of cell cycle process GO:0010564 160 0.074
mammary gland epithelial cell proliferation GO:0033598 24 0.074
response to alkaloid GO:0043279 34 0.074
regulation of multi organism process GO:0043900 111 0.074
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.074
alpha beta t cell activation GO:0046631 91 0.073
regulation of myotube differentiation GO:0010830 62 0.073
lymphocyte differentiation GO:0030098 242 0.073
regulation of mitotic cell cycle phase transition GO:1901990 73 0.073
negative regulation of anoikis GO:2000811 2 0.073
regulation of cell migration GO:0030334 219 0.073
odontogenesis of dentin containing tooth GO:0042475 66 0.072
response to starvation GO:0042594 65 0.072
Human
negative regulation of cell motility GO:2000146 61 0.071
regulation of protein localization GO:0032880 231 0.071
positive regulation of neuron maturation GO:0014042 2 0.071
nephron development GO:0072006 109 0.071
epithelial cell proliferation GO:0050673 174 0.071
gonad development GO:0008406 141 0.071
negative regulation of ossification GO:0030279 49 0.071
positive regulation of protein phosphorylation GO:0001934 242 0.071
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.071
hypothalamus development GO:0021854 16 0.071
positive regulation of b cell apoptotic process GO:0002904 4 0.070
diencephalon development GO:0021536 63 0.070
nephron morphogenesis GO:0072028 69 0.070
negative regulation of protein processing GO:0010955 79 0.070
male gonad development GO:0008584 88 0.069
mammary gland morphogenesis GO:0060443 54 0.069
positive regulation of cellular response to oxidative stress GO:1900409 6 0.069
positive regulation of apoptotic process GO:0043065 217 0.068
cell type specific apoptotic process GO:0097285 268 0.068
renal tubule development GO:0061326 87 0.068
positive regulation of cytoplasmic transport GO:1903651 40 0.068
regulation of endopeptidase activity GO:0052548 89 0.068
nephron epithelium development GO:0072009 92 0.068
b cell activation GO:0042113 161 0.068
negative regulation of cell development GO:0010721 169 0.067
regulation of cysteine type endopeptidase activity GO:2000116 65 0.067
regulation of ossification GO:0030278 112 0.067
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.066
purine containing compound metabolic process GO:0072521 311 0.066
branching morphogenesis of an epithelial tube GO:0048754 159 0.066
cellular response to oxygen levels GO:0071453 20 0.066
Human
positive regulation of protein modification process GO:0031401 299 0.066
behavioral fear response GO:0001662 28 0.066
negative regulation of neuron apoptotic process GO:0043524 92 0.066
cell growth GO:0016049 130 0.065
myeloid cell homeostasis GO:0002262 114 0.065
lymphocyte apoptotic process GO:0070227 54 0.065
negative regulation of cell migration GO:0030336 59 0.065
oocyte development GO:0048599 33 0.065
regulation of cell cycle phase transition GO:1901987 77 0.064
cellular response to dna damage stimulus GO:0006974 207 0.064
cell matrix adhesion GO:0007160 68 0.064
protein homooligomerization GO:0051260 43 0.064
limbic system development GO:0021761 72 0.063
leukocyte proliferation GO:0070661 172 0.063
gland development GO:0048732 330 0.063
negative regulation of proteolysis GO:0045861 74 0.063
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.063
response to organic cyclic compound GO:0014070 198 0.063
Human
regulation of striated muscle cell differentiation GO:0051153 81 0.063
positive regulation of leukocyte apoptotic process GO:2000108 21 0.063
positive regulation of neuroepithelial cell differentiation GO:1902913 5 0.062
positive regulation of response to oxidative stress GO:1902884 6 0.062
positive regulation of cell motility GO:2000147 116 0.062
regulation of cell cycle g1 s phase transition GO:1902806 35 0.062
negative regulation of cell cycle process GO:0010948 69 0.061
homeostasis of number of cells within a tissue GO:0048873 25 0.061
myotube cell development GO:0014904 60 0.061
neural nucleus development GO:0048857 22 0.061
positive regulation of muscle cell differentiation GO:0051149 39 0.061
digestive tract development GO:0048565 190 0.060
epidermis development GO:0008544 187 0.060
ureteric bud morphogenesis GO:0060675 62 0.060
negative regulation of intracellular transport GO:0032387 38 0.059
single organism cell adhesion GO:0098602 156 0.059
telencephalon development GO:0021537 186 0.059
cd8 positive alpha beta t cell lineage commitment GO:0043375 1 0.058
negative regulation of cell growth GO:0030308 44 0.058
negative regulation of cell cycle phase transition GO:1901988 48 0.057
camera type eye development GO:0043010 266 0.057
regulation of epithelial cell proliferation GO:0050678 141 0.057
neuron migration GO:0001764 122 0.057
appendage development GO:0048736 166 0.056
positive regulation of cell migration GO:0030335 109 0.056
regulation of cell growth GO:0001558 91 0.056
mesonephric tubule morphogenesis GO:0072171 63 0.056
positive regulation of melanocyte differentiation GO:0045636 5 0.056
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 3 0.056
development of primary sexual characteristics GO:0045137 143 0.056
regulation of cell division GO:0051302 76 0.055
tissue remodeling GO:0048771 102 0.055
positive regulation of proteolysis GO:0045862 85 0.055
regulation of osteoblast proliferation GO:0033688 15 0.054
negative regulation of fibroblast proliferation GO:0048147 14 0.054
negative regulation of protein metabolic process GO:0051248 282 0.054
regulation of organ morphogenesis GO:2000027 144 0.054
cell maturation GO:0048469 127 0.053
negative regulation of cellular component organization GO:0051129 194 0.053
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.053
apoptotic process in bone marrow GO:0071839 1 0.053
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.053
apoptotic process involved in embryonic digit morphogenesis GO:1902263 3 0.053
oocyte differentiation GO:0009994 35 0.053
smooth muscle cell migration GO:0014909 10 0.052
post embryonic organ morphogenesis GO:0048563 8 0.052
glomerulus development GO:0032835 40 0.052
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.052
osteoblast proliferation GO:0033687 18 0.051
regulation of response to oxidative stress GO:1902882 19 0.051
tissue homeostasis GO:0001894 115 0.051
cellular response to organonitrogen compound GO:0071417 145 0.051
developmental maturation GO:0021700 193 0.051
response to drug GO:0042493 75 0.050
molting cycle GO:0042303 90 0.050
protein processing GO:0016485 163 0.050
retina development in camera type eye GO:0060041 119 0.048
positive t cell selection GO:0043368 23 0.048

Pmaip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org