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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cellular response to oxidative stress"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cellular response to oxidative stress" (in gray)

Name	Description	Probability	Func Analog Organism
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.996
Mapk14	mitogen-activated protein kinase 14	0.918	Fly
Bax	BCL2-associated X protein	0.866	Mouse
Mmp2	matrix metallopeptidase 2	0.809	Mouse
Kit	kit oncogene	0.460
Vegfa	vascular endothelial growth factor A	0.399
Lox	lysyl oxidase	0.381
Trp53	transformation related protein 53	0.374
Mapk11	mitogen-activated protein kinase 11	0.361	Fly
Fbn1	fibrillin 1	0.322
Apoe	apolipoprotein E	0.298
Trib3	tribbles homolog 3 (Drosophila)	0.287
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.274
Bcl2	B-cell leukemia/lymphoma 2	0.253	Mouse
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.237
Ltbp2	latent transforming growth factor beta binding protein 2	0.227	Mouse
Prnp	prion protein	0.216
Mfn2	mitofusin 2	0.215
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.191
Pten	phosphatase and tensin homolog	0.179
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.176
Aebp1	AE binding protein 1	0.137
Mitf	microphthalmia-associated transcription factor	0.129
S1pr2	sphingosine-1-phosphate receptor 2	0.121
Mapkapk2	MAP kinase-activated protein kinase 2	0.119
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.119
Ldlr	low density lipoprotein receptor	0.117
Lyst	lysosomal trafficking regulator	0.110
Gab1	growth factor receptor bound protein 2-associated protein 1	0.110
Cyld	cylindromatosis (turban tumor syndrome)	0.109
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.107
Bag3	BCL2-associated athanogene 3	0.106
Rps3	ribosomal protein S3	0.104
Rpgrip1l	Rpgrip1-like	0.102
Bak1	BCL2-antagonist/killer 1	0.099	Mouse
Kitl	kit ligand	0.096
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.095
Vcp	valosin containing protein	0.090
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.090
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.088
Tcrb	T-cell receptor beta chain	0.082
Ep300	E1A binding protein p300	0.079
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.076
Vhl	von Hippel-Lindau tumor suppressor	0.074
Slc12a6	solute carrier family 12, member 6	0.071
Fbln5	fibulin 5	0.071
Clec4e	C-type lectin domain family 4, member e	0.070
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.070
Atf2	activating transcription factor 2	0.069
Sftpd	surfactant associated protein D	0.068
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.068
Tgfb1	transforming growth factor, beta 1	0.067
Hspa5	heat shock protein 5	0.064
Phlda3	pleckstrin homology-like domain, family A, member 3	0.063
Pcolce	procollagen C-endopeptidase enhancer protein	0.063
Idua	iduronidase, alpha-L-	0.063
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.062
Mfap4	microfibrillar-associated protein 4	0.058
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.057
Sox10	SRY-box containing gene 10	0.054
Il1rn	interleukin 1 receptor antagonist	0.052
Edn1	endothelin 1	0.052
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.051
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.051
Cul7	cullin 7	0.049
Thbs2	thrombospondin 2	0.048
Gpx1	glutathione peroxidase 1	0.047
Sva	seminal vesicle antigen	0.046
Grb2	growth factor receptor bound protein 2	0.046
Loxl1	lysyl oxidase-like 1	0.045
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.045
Htra3	HtrA serine peptidase 3	0.044
Tgfbr2	transforming growth factor, beta receptor II	0.042
Lrp2	low density lipoprotein receptor-related protein 2	0.042
Col1a2	collagen, type I, alpha 2	0.042
Tlr4	toll-like receptor 4	0.041
Chi3l1	chitinase 3-like 1	0.041
Timp2	tissue inhibitor of metalloproteinase 2	0.041
Sebox	SEBOX homeobox	0.039
Ret	ret proto-oncogene	0.038
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.038
Rarb	retinoic acid receptor, beta	0.036
Sqstm1	sequestosome 1	0.036
Fpr2	formyl peptide receptor 2	0.036
Mmp3	matrix metallopeptidase 3	0.036
Sykb	spleen tyrosine kinase	0.035
Emp2	epithelial membrane protein 2	0.034
Bst1	bone marrow stromal cell antigen 1	0.034
Stat3	signal transducer and activator of transcription 3	0.034
Tgfb3	transforming growth factor, beta 3	0.034
Aars	alanyl-tRNA synthetase	0.034
Gaa	glucosidase, alpha, acid	0.034
Rplp0	ribosomal protein, large, P0	0.033
S1pr3	sphingosine-1-phosphate receptor 3	0.033
Axin1	axin 1	0.033
Selp	selectin, platelet	0.033
Aplp2	amyloid beta (A4) precursor-like protein 2	0.032
Mmp8	matrix metallopeptidase 8	0.032	Mouse
Cd151	CD151 antigen	0.031
Ccr2	chemokine (C-C motif) receptor 2	0.031
Kif27	kinesin family member 27	0.031
Sprr2h	small proline-rich protein 2H	0.031
Ece1	endothelin converting enzyme 1	0.031
Cd248	CD248 antigen, endosialin	0.030
Mn1	meningioma 1	0.029
Prdx1	peroxiredoxin 1	0.029
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.029
Smo	smoothened homolog (Drosophila)	0.029
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.029
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.029
Ccl2	chemokine (C-C motif) ligand 2	0.028
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.028
Il6	interleukin 6	0.028
Igfbp6	insulin-like growth factor binding protein 6	0.028
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.028
Mfap5	microfibrillar associated protein 5	0.028
Htra1	HtrA serine peptidase 1	0.027
Il1b	interleukin 1 beta	0.027
Lama5	laminin, alpha 5	0.027
Hsph1	heat shock 105kDa/110kDa protein 1	0.026
Alas2	aminolevulinic acid synthase 2, erythroid	0.026
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.026
Timp3	tissue inhibitor of metalloproteinase 3	0.026
Casp3	caspase 3	0.026
Angptl2	angiopoietin-like 2	0.026
Becn1	beclin 1, autophagy related	0.026
Plaa	phospholipase A2, activating protein	0.026
Wisp2	WNT1 inducible signaling pathway protein 2	0.025
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.025
C5ar1	complement component 5a receptor 1	0.025
Notch2	Notch gene homolog 2 (Drosophila)	0.025
Lamc2	laminin, gamma 2	0.024
Timp1	tissue inhibitor of metalloproteinase 1	0.024
Myo7a	myosin VIIA	0.024
Saa3	serum amyloid A 3	0.024
Rpl8	ribosomal protein L8	0.024
Rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.024
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.024
Prelp	proline arginine-rich end leucine-rich repeat	0.023
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.023
Fpr1	formyl peptide receptor 1	0.023
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.023
Il6st	interleukin 6 signal transducer	0.023
Rpl6	ribosomal protein L6	0.022
Fxyd1	FXYD domain-containing ion transport regulator 1	0.022
Rps3a	ribosomal protein S3A	0.022
Rps2	ribosomal protein S2	0.022
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.022
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.022
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.022
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.022
Mgp	matrix Gla protein	0.022
Tal1	T-cell acute lymphocytic leukemia 1	0.021
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.021
Lpl	lipoprotein lipase	0.021
Trim47	tripartite motif-containing 47	0.021
Slc12a4	solute carrier family 12, member 4	0.021
Spp1	secreted phosphoprotein 1	0.021
Bgn	biglycan	0.020
Ngp	neutrophilic granule protein	0.020
Srpx	sushi-repeat-containing protein	0.020
Cdh1	cadherin 1	0.020
Chrnb1	cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)	0.020
Krt6a	keratin 6A	0.020
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.019
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.019
Figf	c-fos induced growth factor	0.019
Mag	myelin-associated glycoprotein	0.019
Ctsb	cathepsin B	0.019
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.019
Mkl2	MKL/myocardin-like 2	0.019
Gdnf	glial cell line derived neurotrophic factor	0.019
Tagln	transgelin	0.019
Rpl7a	ribosomal protein L7A	0.019
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.019
Slfn4	schlafen 4	0.019
Glrp1	glutamine repeat protein 1	0.018
Mapk9	mitogen-activated protein kinase 9	0.018
Chd2	chromodomain helicase DNA binding protein 2	0.018
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.018
Mfrp	membrane-type frizzled-related protein	0.018
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.018
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.018
Gm10393	predicted gene 10393	0.018
Ctsd	cathepsin D	0.018
Cxcr4	chemokine (C-X-C motif) receptor 4	0.018
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.018
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.018
Msln	mesothelin	0.017
Gdpd5	glycerophosphodiester phosphodiesterase domain containing 5	0.017
Gpx3	glutathione peroxidase 3	0.017	Mouse
Ngf	nerve growth factor	0.017
Bcl2l1	BCL2-like 1	0.017	Mouse
Bcl6	B-cell leukemia/lymphoma 6	0.017
Srpx2	sushi-repeat-containing protein, X-linked 2	0.017
Dpt	dermatopontin	0.017
Prrx2	paired related homeobox 2	0.017
Leprel2	leprecan-like 2	0.017
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.017
Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	0.016
Il17a	interleukin 17A	0.016
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.016
Prrx1	paired related homeobox 1	0.016
Ednra	endothelin receptor type A	0.016	Mouse
Tnnt2	troponin T2, cardiac	0.016
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.016
Tuba1a	tubulin, alpha 1A	0.016
Ptgis	prostaglandin I2 (prostacyclin) synthase	0.016
Cav1	caveolin 1, caveolae protein	0.016
Col6a1	collagen, type VI, alpha 1	0.016
Cst8	cystatin 8 (cystatin-related epididymal spermatogenic)	0.016
Foxi3	forkhead box I3	0.016
Dnm1l	dynamin 1-like	0.016
Ltbp3	latent transforming growth factor beta binding protein 3	0.016	Mouse
Mrvi1	MRV integration site 1	0.016
Olfml3	olfactomedin-like 3	0.016
Agtr2	angiotensin II receptor, type 2	0.015
Gba	glucosidase, beta, acid	0.015
Mt1	metallothionein 1	0.015
Wt1	Wilms tumor 1 homolog	0.015
Ulk4	unc-51-like kinase 4 (C. elegans)	0.015
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.015
Igh	immunoglobulin heavy chain complex	0.015
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.015
Cd44	CD44 antigen	0.015
Wbp7	WW domain binding protein 7	0.015
Dpep1	dipeptidase 1 (renal)	0.015
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.015
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.015
Tpm2	tropomyosin 2, beta	0.015
Ubc	ubiquitin C	0.015
Ch25h	cholesterol 25-hydroxylase	0.015
Rps5	ribosomal protein S5	0.015
Sulf1	sulfatase 1	0.015
Msr1	macrophage scavenger receptor 1	0.015
Prkce	protein kinase C, epsilon	0.015
Hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.015
Tcn2	transcobalamin 2	0.015
Stk4	serine/threonine kinase 4	0.015
Gypa	glycophorin A	0.014
Ptgs2	prostaglandin-endoperoxide synthase 2	0.014
Cdk5rap3	CDK5 regulatory subunit associated protein 3	0.014
Fcgr1	Fc receptor, IgG, high affinity I	0.014
Ythdc1	YTH domain containing 1	0.014
Ppia	peptidylprolyl isomerase A	0.014
Copz2	coatomer protein complex, subunit zeta 2	0.014
Mmp9	matrix metallopeptidase 9	0.014	Mouse
Gpx5	glutathione peroxidase 5	0.014	Mouse
Pdgfa	platelet derived growth factor, alpha	0.014
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.014
Ptgds	prostaglandin D2 synthase (brain)	0.014
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.014
Fkbp10	FK506 binding protein 10	0.014
Pax3	paired box gene 3	0.014
Mt2	metallothionein 2	0.014
Lamp1	lysosomal-associated membrane protein 1	0.014
Ptger3	prostaglandin E receptor 3 (subtype EP3)	0.014
Scara3	scavenger receptor class A, member 3	0.013
Il1a	interleukin 1 alpha	0.013
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.013
Prkci	protein kinase C, iota	0.013
Itgb5	integrin beta 5	0.013
Il1r2	interleukin 1 receptor, type II	0.013
Atf5	activating transcription factor 5	0.013
Plat	plasminogen activator, tissue	0.013
Sh2d1b1	SH2 domain protein 1B1	0.013
Rpl10	ribosomal protein 10	0.013
Tcp11	t-complex protein 11	0.013
Ncoa3	nuclear receptor coactivator 3	0.013
Tmem119	transmembrane protein 119	0.013
Aco1	aconitase 1	0.013
Ftl2	ferritin light chain 2	0.013
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.013
Ccnd1	cyclin D1	0.013
Gzmk	granzyme K	0.013
Psap	prosaposin	0.013
Srsf1	serine/arginine-rich splicing factor 1	0.013
Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	0.013
Rhbdf1	rhomboid family 1 (Drosophila)	0.013
Snta1	syntrophin, acidic 1	0.013
Dcn	decorin	0.013
Rb1	retinoblastoma 1	0.013
Ifngr1	interferon gamma receptor 1	0.013
Sgpl1	sphingosine phosphate lyase 1	0.013
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.013
Psmb3	proteasome (prosome, macropain) subunit, beta type 3	0.013
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.012
Ghrl	ghrelin	0.012
Plxnd1	plexin D1	0.012
Cxcl2	chemokine (C-X-C motif) ligand 2	0.012
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.012
Aga	aspartylglucosaminidase	0.012
Chi3l3	chitinase 3-like 3	0.012
Rara	retinoic acid receptor, alpha	0.012
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.012
Odz1	odd Oz/ten-m homolog 1 (Drosophila)	0.012
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.012
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.012
Cnn1	calponin 1	0.012
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.012
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
Egln1	EGL nine homolog 1 (C. elegans)	0.012
Skil	SKI-like	0.012
Slc26a4	solute carrier family 26, member 4	0.012
Mapk12	mitogen-activated protein kinase 12	0.012	Fly
Amelx	amelogenin X chromosome	0.012
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.012
Ager	advanced glycosylation end product-specific receptor	0.012
Hip1	huntingtin interacting protein 1	0.012
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.012
Col16a1	collagen, type XVI, alpha 1	0.012
Thbd	thrombomodulin	0.012
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.012
Adora2b	adenosine A2b receptor	0.012
Foxo1	forkhead box O1	0.012
Clec4d	C-type lectin domain family 4, member d	0.012
Fcgrt	Fc receptor, IgG, alpha chain transporter	0.012
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.012
Tm4sf1	transmembrane 4 superfamily member 1	0.012
Ccl17	chemokine (C-C motif) ligand 17	0.012
Mcpt2	mast cell protease 2	0.011
Myl9	myosin, light polypeptide 9, regulatory	0.011
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.011
Myc	myelocytomatosis oncogene	0.011
Bmp4	bone morphogenetic protein 4	0.011
Eya1	eyes absent 1 homolog (Drosophila)	0.011
Agtr1a	angiotensin II receptor, type 1a	0.011
Fstl3	follistatin-like 3	0.011
Prl3d1	prolactin family 3, subfamily d, member 1	0.011
Sorbs3	sorbin and SH3 domain containing 3	0.011
Bid	BH3 interacting domain death agonist	0.011
Gcsh	glycine cleavage system protein H (aminomethyl carrier)	0.011
Fhl2	four and a half LIM domains 2	0.011
Hoxa1	homeobox A1	0.011
Ftl1	ferritin light chain 1	0.011
Il18rap	interleukin 18 receptor accessory protein	0.011
Trem3	triggering receptor expressed on myeloid cells 3	0.011
Ccl7	chemokine (C-C motif) ligand 7	0.011
Podxl	podocalyxin-like	0.011
C78513	EST C78513	0.011
Foxc2	forkhead box C2	0.011
Gstm2	glutathione S-transferase, mu 2	0.011
Ush1g	Usher syndrome 1G homolog (human)	0.011
Snca	synuclein, alpha	0.011	Human
Hoxa3	homeobox A3	0.011
Cx3cr1	chemokine (C-X3-C) receptor 1	0.011
Irg1	immunoresponsive gene 1	0.011
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.011
Spink4	serine peptidase inhibitor, Kazal type 4	0.011
Cpxm1	carboxypeptidase X 1 (M14 family)	0.011
Lepre1	leprecan 1	0.011
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.011
Ntn1	netrin 1	0.010
Fgfr1	fibroblast growth factor receptor 1	0.010
Tppp3	tubulin polymerization-promoting protein family member 3	0.010
Calr	calreticulin	0.010
Fancc	Fanconi anemia, complementation group C	0.010
Angptl4	angiopoietin-like 4	0.010
Gpx8	glutathione peroxidase 8 (putative)	0.010
Aldh18a1	aldehyde dehydrogenase 18 family, member A1	0.010
Mettl7a1	methyltransferase like 7A1	0.010
Pxn	paxillin	0.010
Wisp1	WNT1 inducible signaling pathway protein 1	0.010
Btg1	B-cell translocation gene 1, anti-proliferative	0.010
Smad1	MAD homolog 1 (Drosophila)	0.010
Cxcl1	chemokine (C-X-C motif) ligand 1	0.010
B3gnt9-ps	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene	0.010
Tle6	transducin-like enhancer of split 6, homolog of Drosophila E(spl)	0.010
Asb6	ankyrin repeat and SOCS box-containing 6	0.010
Vmn2r26	vomeronasal 2, receptor 26	0.010
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.010
Pkd1	polycystic kidney disease 1 homolog	0.010
Clu	clusterin	0.010
Mrc2	mannose receptor, C type 2	0.010
Bdkrb1	bradykinin receptor, beta 1	0.010
Ltb4r1	leukotriene B4 receptor 1	0.010
Tg	thyroglobulin	0.010
Stom	stomatin	0.010