Mus musculus

205 known processes

Pou5f1

POU domain, class 5, transcription factor 1

(Aliases: Otf-3,Oct4,Oct3,Oct3/4,Otf-4,Otf3,Oct-3,Oct-4,Otf4,Oct-3/4,Otf3-rs7,Otf3g)

Pou5f1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transdifferentiation GO:0060290 1 1.000
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 1.000
chromatin modification GO:0016568 187 1.000
Human
covalent chromatin modification GO:0016569 163 1.000
Human
inner cell mass cell proliferation GO:0001833 15 1.000
dna metabolic process GO:0006259 303 1.000
chromatin organization GO:0006325 206 1.000
Human
histone modification GO:0016570 159 1.000
olfactory nerve development GO:0021553 3 0.999
blastocyst growth GO:0001832 23 0.998
ureteric bud invasion GO:0072092 3 0.998
negative regulation of gene expression epigenetic GO:0045814 15 0.996
Human
cell fate commitment GO:0045165 210 0.995
blastocyst development GO:0001824 80 0.994
dna alkylation GO:0006305 43 0.994
gene silencing GO:0016458 38 0.994
Human
double strand break repair GO:0006302 48 0.994
bmp signaling pathway GO:0030509 93 0.993
Human
chromatin assembly or disassembly GO:0006333 16 0.992
neuroblast differentiation GO:0014016 2 0.989
neural tube development GO:0021915 160 0.988
dna methylation GO:0006306 43 0.987
camera type eye development GO:0043010 266 0.983
Mouse
olfactory bulb interneuron development GO:0021891 7 0.982
trophectodermal cell differentiation GO:0001829 21 0.980
cardiac cell fate specification GO:0060912 2 0.980
regionalization GO:0003002 337 0.980
digestive tract development GO:0048565 190 0.979
dna methylation involved in gamete generation GO:0043046 15 0.971
dna recombination GO:0006310 92 0.971
eyelid development in camera type eye GO:0061029 9 0.968
protein dna complex subunit organization GO:0071824 28 0.966
pituitary gland development GO:0021983 38 0.963
Mouse
epithelial tube morphogenesis GO:0060562 303 0.961
chromatin silencing GO:0006342 15 0.961
Human
endodermal cell fate commitment GO:0001711 12 0.960
endodermal cell fate specification GO:0001714 4 0.953
Human
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.947
histone acetylation GO:0016573 41 0.947
mesoderm development GO:0007498 100 0.946
neural tube closure GO:0001843 90 0.945
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.935
formation of primary germ layer GO:0001704 77 0.933
ureteric bud elongation GO:0060677 6 0.930
digestive system development GO:0055123 200 0.928
dna repair GO:0006281 107 0.921
negative regulation of mesoderm development GO:2000381 8 0.902
embryonic organ morphogenesis GO:0048562 276 0.900
Mouse
protein acylation GO:0043543 64 0.896
forebrain neuron fate commitment GO:0021877 13 0.894
chromatin remodeling GO:0006338 32 0.889
regulation of cell cycle phase transition GO:1901987 77 0.886
axon guidance GO:0007411 141 0.880
Mouse
muscle cell differentiation GO:0042692 261 0.876
internal protein amino acid acetylation GO:0006475 42 0.875
primary neural tube formation GO:0014020 95 0.874
diencephalon development GO:0021536 63 0.869
Mouse
stem cell development GO:0048864 219 0.866
embryonic eye morphogenesis GO:0048048 29 0.866
tube formation GO:0035148 140 0.862
cardiocyte differentiation GO:0035051 87 0.861
Human
stem cell fate specification GO:0048866 3 0.838
regulation of bmp signaling pathway GO:0030510 60 0.834
blastocyst formation GO:0001825 33 0.834
respiratory system development GO:0060541 190 0.821
Mouse
neuron projection guidance GO:0097485 141 0.821
Mouse
nephron development GO:0072006 109 0.820
Mouse
forebrain generation of neurons GO:0021872 63 0.818
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.812
Mouse
lung development GO:0030324 164 0.812
histone deacetylation GO:0016575 26 0.807
cellular response to lipid GO:0071396 145 0.806
immunoglobulin production GO:0002377 73 0.796
Mouse
forebrain neuron differentiation GO:0021879 52 0.795
Mouse
melanocyte differentiation GO:0030318 25 0.793
axonogenesis GO:0007409 274 0.789
Mouse
dendrite development GO:0016358 115 0.783
organ growth GO:0035265 117 0.775
dna conformation change GO:0071103 37 0.773
dna modification GO:0006304 50 0.771
somatic stem cell maintenance GO:0035019 47 0.768
Human
rostrocaudal neural tube patterning GO:0021903 12 0.766
gastrulation GO:0007369 116 0.766
mesoderm morphogenesis GO:0048332 64 0.765
regulation of cell cycle process GO:0010564 160 0.763
sensory organ morphogenesis GO:0090596 242 0.759
Mouse
macromolecule methylation GO:0043414 120 0.759
developmental induction GO:0031128 34 0.754
Human Mouse
metanephric renal vesicle formation GO:0072093 4 0.753
appendage development GO:0048736 166 0.753
mesonephric tubule development GO:0072164 94 0.746
cardiac cell fate commitment GO:0060911 10 0.742
Human
trophectodermal cellular morphogenesis GO:0001831 3 0.742
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.737
respiratory tube development GO:0030323 167 0.735
regulation of organ morphogenesis GO:2000027 144 0.728
Human
positive regulation of immature t cell proliferation GO:0033091 4 0.725
morphogenesis of embryonic epithelium GO:0016331 159 0.724
regulation of asymmetric cell division GO:0009786 4 0.718
neural tube formation GO:0001841 108 0.716
stem cell maintenance GO:0019827 130 0.715
multi multicellular organism process GO:0044706 109 0.713
regulation of cell cycle g2 m phase transition GO:1902749 10 0.710
cellular response to dna damage stimulus GO:0006974 207 0.709
histone h4 acetylation GO:0043967 10 0.707
peptidyl lysine modification GO:0018205 77 0.694
epithelial tube formation GO:0072175 130 0.693
digestive tract morphogenesis GO:0048546 147 0.688
regulation of mitotic cell cycle phase transition GO:1901990 73 0.686
telencephalon development GO:0021537 186 0.686
Mouse
somatic diversification of immune receptors GO:0002200 53 0.685
methylation GO:0032259 134 0.683
sensory perception of sound GO:0007605 97 0.682
Mouse
stem cell differentiation GO:0048863 268 0.681
ribonucleoside metabolic process GO:0009119 245 0.679
atp dependent chromatin remodeling GO:0043044 9 0.674
tube closure GO:0060606 91 0.671
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.667
cerebral cortex neuron differentiation GO:0021895 19 0.661
embryonic epithelial tube formation GO:0001838 130 0.658
ureteric bud development GO:0001657 94 0.654
embryonic skeletal system development GO:0048706 120 0.635
inner ear morphogenesis GO:0042472 101 0.633
Mouse
olfactory lobe development GO:0021988 32 0.632
striated muscle cell development GO:0055002 125 0.629
negative regulation of metanephros development GO:0072217 6 0.628
neural tube patterning GO:0021532 43 0.625
methylation dependent chromatin silencing GO:0006346 6 0.624
Human
protein deacetylation GO:0006476 32 0.622
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.610
Human
purine nucleoside monophosphate catabolic process GO:0009128 58 0.606
circadian regulation of gene expression GO:0032922 48 0.597
endocrine system development GO:0035270 98 0.596
Mouse
mesoderm formation GO:0001707 62 0.596
negative regulation of ectoderm development GO:2000384 2 0.595
appendage morphogenesis GO:0035107 149 0.593
olfactory bulb interneuron differentiation GO:0021889 12 0.585
skeletal system development GO:0001501 356 0.582
macromolecule deacylation GO:0098732 37 0.573
positive regulation of stem cell proliferation GO:2000648 59 0.572
epithelial to mesenchymal transition GO:0001837 47 0.562
skeletal system morphogenesis GO:0048705 203 0.561
canonical wnt signaling pathway GO:0060070 130 0.558
Human
cardiac chamber development GO:0003205 108 0.549
Mouse
atp catabolic process GO:0006200 55 0.544
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.543
Human
embryonic placenta development GO:0001892 98 0.540
embryonic skeletal system morphogenesis GO:0048704 91 0.539
central nervous system neuron development GO:0021954 67 0.536
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.536
cell cell signaling involved in cell fate commitment GO:0045168 35 0.535
Human Mouse
development of primary sexual characteristics GO:0045137 143 0.532
endocardial cell differentiation GO:0060956 4 0.531
regulation of cardiac muscle tissue development GO:0055024 31 0.530
muscle tissue development GO:0060537 308 0.530
Mouse
dna packaging GO:0006323 30 0.527
cell maturation GO:0048469 127 0.526
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.522
nucleosome positioning GO:0016584 4 0.521
dna methylation involved in embryo development GO:0043045 6 0.517
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.514
neuroepithelial cell differentiation GO:0060563 37 0.511
mesenchymal cell development GO:0014031 93 0.508
regulation of chondrocyte differentiation GO:0032330 33 0.507
heart morphogenesis GO:0003007 178 0.503
Mouse
negative regulation of mesodermal cell fate specification GO:0042662 3 0.501
regulation of cardiac muscle cell proliferation GO:0060043 23 0.500
cardiac muscle tissue development GO:0048738 130 0.500
Mouse
meiosis i GO:0007127 60 0.499
renal vesicle development GO:0072087 17 0.487
posttranscriptional gene silencing GO:0016441 10 0.486
Human
septum primum development GO:0003284 4 0.485
regulation of hippo signaling GO:0035330 1 0.485
hypermethylation of cpg island GO:0044027 3 0.482
forebrain development GO:0030900 302 0.469
Mouse
embryonic camera type eye development GO:0031076 36 0.468
cell fate specification GO:0001708 72 0.466
Human Mouse
regulation of ectoderm development GO:2000383 2 0.465
somatic cell dna recombination GO:0016444 51 0.464
response to ionizing radiation GO:0010212 42 0.463
glial cell differentiation GO:0010001 131 0.461
Mouse
sensory perception of mechanical stimulus GO:0050954 107 0.460
Mouse
epithelial cell development GO:0002064 159 0.459
retina development in camera type eye GO:0060041 119 0.457
Mouse
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.455
somitogenesis GO:0001756 69 0.437
positive regulation of bmp signaling pathway GO:0030513 23 0.436
limb development GO:0060173 166 0.435
multi organism behavior GO:0051705 62 0.434
Mouse
cell fate determination GO:0001709 32 0.433
Human
maintenance of chromatin silencing GO:0006344 2 0.433
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.428
gonad development GO:0008406 141 0.427
tongue development GO:0043586 18 0.424
response to retinoic acid GO:0032526 56 0.422
cochlea development GO:0090102 35 0.420
Mouse
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.419
smoothened signaling pathway GO:0007224 105 0.418
cardiac ventricle development GO:0003231 83 0.416
Mouse
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.413
renal tubule development GO:0061326 87 0.410
Mouse
leukocyte differentiation GO:0002521 342 0.408
Mouse
pigment cell differentiation GO:0050931 27 0.407
nerve development GO:0021675 67 0.400
Mouse
protein deacylation GO:0035601 36 0.399
regulation of mitotic cell cycle GO:0007346 126 0.399
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.399
sensory organ boundary specification GO:0008052 1 0.396
ribonucleotide catabolic process GO:0009261 208 0.395
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.394
limb morphogenesis GO:0035108 149 0.392
mesenchymal cell differentiation GO:0048762 107 0.389
gland development GO:0048732 330 0.386
Mouse
cardiac septum development GO:0003279 59 0.384
positive regulation of growth GO:0045927 104 0.382
Mouse
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.382
regulation of dna recombination GO:0000018 34 0.380
negative regulation of cell proliferation GO:0008285 296 0.380
positive regulation of extracellular matrix organization GO:1903055 4 0.376
renal vesicle formation GO:0072033 8 0.375
male meiosis GO:0007140 37 0.375
positive regulation of cell activation GO:0050867 158 0.375
male gonad development GO:0008584 88 0.374
lung epithelial cell differentiation GO:0060487 29 0.372
nucleoside monophosphate metabolic process GO:0009123 85 0.371
male sex differentiation GO:0046661 109 0.371
histone h4 k12 acetylation GO:0043983 2 0.370
genetic imprinting GO:0071514 27 0.368
regulation of dna methylation GO:0044030 12 0.363
placenta development GO:0001890 140 0.362
ribonucleoside monophosphate catabolic process GO:0009158 57 0.362
erythrocyte differentiation GO:0030218 88 0.361
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.358
multi organism reproductive behavior GO:0044705 29 0.358
nephron epithelium development GO:0072009 92 0.357
Mouse
spinal cord development GO:0021510 81 0.355
olfactory bulb development GO:0021772 30 0.355
cardiac muscle cell differentiation GO:0055007 69 0.355
pigmentation GO:0043473 71 0.354
cardiac chamber formation GO:0003207 10 0.352
purine ribonucleotide metabolic process GO:0009150 290 0.352
renal tubule morphogenesis GO:0061333 72 0.350
lymphocyte differentiation GO:0030098 242 0.349
Mouse
cardiac muscle cell development GO:0055013 39 0.343
regulation of leukocyte differentiation GO:1902105 159 0.339
kidney epithelium development GO:0072073 121 0.338
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.337
cell fate determination involved in pattern specification GO:0060582 1 0.336
urogenital system development GO:0001655 261 0.336
Mouse
reproductive behavior GO:0019098 32 0.334
negative regulation of cell fate specification GO:0009996 4 0.332
striated muscle tissue development GO:0014706 293 0.332
Mouse
negative regulation of cellular component organization GO:0051129 194 0.331
ribonucleoside triphosphate catabolic process GO:0009203 199 0.330
forelimb morphogenesis GO:0035136 40 0.328
neural crest cell migration GO:0001755 32 0.327
chromatin assembly GO:0031497 13 0.325
atp metabolic process GO:0046034 75 0.323
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.319
visceral motor neuron differentiation GO:0021524 3 0.319
regulation of cell activation GO:0050865 289 0.319
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 5 0.318
cellular response to acid chemical GO:0071229 68 0.318
regulation of myeloid cell differentiation GO:0045637 96 0.315
ventricular septum development GO:0003281 42 0.315
mesenchyme development GO:0060485 152 0.311
nucleotide catabolic process GO:0009166 217 0.310
central nervous system neuron differentiation GO:0021953 162 0.306
Mouse
embryonic limb morphogenesis GO:0030326 126 0.303
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.303
regulation of heart growth GO:0060420 31 0.303
neurohypophysis development GO:0021985 2 0.300
Mouse
negative regulation of cell cycle GO:0045786 123 0.299
lipid storage GO:0019915 36 0.298
nucleoside triphosphate catabolic process GO:0009143 205 0.298
isotype switching GO:0045190 36 0.297
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.296
positive regulation of cell cycle GO:0045787 92 0.295
sertoli cell differentiation GO:0060008 18 0.295
lens epithelial cell proliferation GO:0097166 1 0.293
endocardial cushion development GO:0003197 26 0.292
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.292
lung epithelium development GO:0060428 37 0.290
mesonephric epithelium development GO:0072163 94 0.289
hematopoietic progenitor cell differentiation GO:0002244 143 0.288
bone development GO:0060348 120 0.286
chondrocyte differentiation GO:0002062 72 0.286
cardiac muscle tissue morphogenesis GO:0055008 44 0.284
Mouse
nephron tubule morphogenesis GO:0072078 68 0.282
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.279
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.277
Mouse
epithelial cell maturation GO:0002070 15 0.275
positive regulation of chondrocyte differentiation GO:0032332 13 0.273
regulation of mesoderm development GO:2000380 12 0.266
cell differentiation in spinal cord GO:0021515 53 0.266
female sex differentiation GO:0046660 84 0.266
peptidyl lysine acetylation GO:0018394 45 0.263
mesenchymal to epithelial transition GO:0060231 12 0.263
closure of optic fissure GO:0061386 2 0.261
myeloid cell differentiation GO:0030099 233 0.257
renal system development GO:0072001 225 0.257
Mouse
regulation of lens epithelial cell proliferation GO:2001109 1 0.257
endoderm formation GO:0001706 20 0.256
male gamete generation GO:0048232 285 0.255
heart growth GO:0060419 45 0.254
ureteric bud morphogenesis GO:0060675 62 0.252
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.251
locomotory behavior GO:0007626 195 0.251
negative regulation of wnt signaling pathway GO:0030178 73 0.250
multicellular organism growth GO:0035264 161 0.249
Mouse
formation of organ boundary GO:0010160 1 0.249
developmental pigmentation GO:0048066 40 0.248
nucleoside phosphate metabolic process GO:0006753 338 0.246
renal vesicle induction GO:0072034 3 0.245
midbrain hindbrain boundary development GO:0030917 9 0.244
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.243
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.243
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.242
cardiac ventricle formation GO:0003211 8 0.242
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.241
Mouse
multicellular organismal reproductive behavior GO:0033057 23 0.238
germ line sex determination GO:0018992 3 0.235
neural precursor cell proliferation GO:0061351 121 0.234
Mouse
inner cell mass cell differentiation GO:0001826 7 0.234
pharyngeal system development GO:0060037 17 0.232
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.230
astrocyte fate commitment GO:0060018 4 0.229
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.227
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.226
nucleoside monophosphate catabolic process GO:0009125 59 0.225
branching involved in ureteric bud morphogenesis GO:0001658 56 0.225
leukocyte activation involved in immune response GO:0002366 126 0.224
regulation of tongue muscle cell differentiation GO:2001035 2 0.223
ventricular septum morphogenesis GO:0060412 27 0.223
oogenesis GO:0048477 56 0.223
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.222
nucleoside phosphate catabolic process GO:1901292 222 0.222
nuclear division GO:0000280 158 0.222
cardiac ventricle morphogenesis GO:0003208 50 0.220
Mouse
epithelial cell morphogenesis GO:0003382 41 0.218
dna methylation on cytosine GO:0032776 5 0.217
chemotaxis GO:0006935 247 0.217
Mouse
renal vesicle morphogenesis GO:0072077 15 0.216
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.214
gall bladder development GO:0061010 2 0.213
morphogenesis of a branching epithelium GO:0061138 193 0.212
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.211
endocardial cushion formation GO:0003272 13 0.207
regulation of cardiac muscle tissue growth GO:0055021 26 0.206
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.206
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.206
regulation of organ growth GO:0046620 61 0.205
spinal cord motor neuron differentiation GO:0021522 35 0.204
determination of left right asymmetry in nervous system GO:0035545 1 0.204
regulation of response to wounding GO:1903034 189 0.204
negative regulation of protein metabolic process GO:0051248 282 0.203
somite development GO:0061053 81 0.203
pallium development GO:0021543 120 0.203
Mouse
cardiac muscle cell myoblast differentiation GO:0060379 8 0.201
positive regulation of leukocyte mediated immunity GO:0002705 70 0.201
positive regulation of leukocyte differentiation GO:1902107 86 0.200
aorta morphogenesis GO:0035909 22 0.198
regulation of stem cell division GO:2000035 4 0.195
positive regulation of adaptive immune response GO:0002821 61 0.195
inner cell mass cellular morphogenesis GO:0001828 1 0.193
changes to dna methylation involved in embryo development GO:1901538 6 0.193
morphogenesis of a branching structure GO:0001763 203 0.192
myeloid leukocyte differentiation GO:0002573 119 0.191
organophosphate catabolic process GO:0046434 232 0.190
mesonephric tubule morphogenesis GO:0072171 63 0.188
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.186
Mouse
outflow tract morphogenesis GO:0003151 53 0.185
negative regulation of bmp signaling pathway GO:0030514 35 0.185
ribonucleoside monophosphate metabolic process GO:0009161 80 0.183
autonomic nervous system development GO:0048483 43 0.182
adaptive immune response GO:0002250 155 0.182
Mouse
glycosyl compound catabolic process GO:1901658 206 0.182
cardiac muscle cell proliferation GO:0060038 31 0.181
positive regulation of chromatin modification GO:1903310 28 0.181
purine nucleotide catabolic process GO:0006195 211 0.180
positive regulation of striated muscle cell differentiation GO:0051155 35 0.180
nephron morphogenesis GO:0072028 69 0.179
positive regulation of mitotic cell cycle GO:0045931 41 0.178
endoderm development GO:0007492 45 0.178
positive regulation of glial cell proliferation GO:0060252 4 0.174
positive regulation of cardiac muscle tissue development GO:0055025 19 0.174
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.174
intracellular receptor signaling pathway GO:0030522 74 0.174
purine ribonucleotide catabolic process GO:0009154 208 0.174
regulation of striated muscle cell differentiation GO:0051153 81 0.172
glycosyl compound metabolic process GO:1901657 246 0.170
pericardium development GO:0060039 16 0.170
purine nucleoside monophosphate metabolic process GO:0009126 81 0.170
ventral spinal cord interneuron fate commitment GO:0060579 14 0.170
regulation of organ formation GO:0003156 34 0.170
Human
mitotic cell cycle GO:0000278 195 0.170
lymphocyte mediated immunity GO:0002449 139 0.169
Mouse
purine nucleoside metabolic process GO:0042278 241 0.169
endocardium formation GO:0060214 4 0.169
response to fibroblast growth factor GO:0071774 47 0.167
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.166
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.165
cell type specific apoptotic process GO:0097285 268 0.165
Mouse
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.165
Mouse
negative regulation of gastrulation GO:2000542 3 0.164
purine nucleoside triphosphate metabolic process GO:0009144 226 0.164
regulation of stem cell proliferation GO:0072091 78 0.163
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.161
posttranscriptional gene silencing by rna GO:0035194 10 0.160
Human
endodermal cell fate determination GO:0007493 2 0.160
carbohydrate derivative catabolic process GO:1901136 231 0.159
regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification GO:0060807 1 0.159
ribonucleoside triphosphate metabolic process GO:0009199 220 0.158
positive regulation of wnt signaling pathway GO:0030177 45 0.157
embryonic appendage morphogenesis GO:0035113 126 0.156
mitotic cell cycle process GO:1903047 159 0.155
ureter urothelium development GO:0072190 3 0.154
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.153
mesonephros development GO:0001823 97 0.153
notochord morphogenesis GO:0048570 10 0.152
meiotic cell cycle GO:0051321 122 0.152
gene silencing by rna GO:0031047 19 0.152
Human
male germ line sex determination GO:0019100 2 0.151
mesenchyme morphogenesis GO:0072132 32 0.151
regulation of adaptive immune response GO:0002819 90 0.151
mammary gland epithelium development GO:0061180 65 0.151
lung cell differentiation GO:0060479 30 0.150
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.150
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.149
negative regulation of kidney development GO:0090185 15 0.148
stem cell division GO:0017145 30 0.147
development of primary male sexual characteristics GO:0046546 88 0.147
axis elongation GO:0003401 30 0.147
negative regulation of cell cycle phase transition GO:1901988 48 0.146
regulation of lymphocyte mediated immunity GO:0002706 84 0.146
forebrain neuron development GO:0021884 30 0.144
regulation of cardiac cell fate specification GO:2000043 1 0.144
regulation of cardiac chamber morphogenesis GO:1901219 2 0.143
branching morphogenesis of an epithelial tube GO:0048754 159 0.143
regulation of cell cycle GO:0051726 281 0.141
epidermis development GO:0008544 187 0.141
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.141
morphogenesis of an epithelial sheet GO:0002011 27 0.140
b cell activation involved in immune response GO:0002312 50 0.139
male genitalia development GO:0030539 20 0.139
regulation of epithelial cell proliferation GO:0050678 141 0.137
purine ribonucleoside metabolic process GO:0046128 241 0.137
positive regulation of mesonephros development GO:0061213 20 0.136
dna hypermethylation GO:0044026 3 0.136
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.135
negative regulation of chromatin modification GO:1903309 19 0.135
regulation of muscle tissue development GO:1901861 97 0.135
tongue muscle cell differentiation GO:0035981 2 0.134
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.134
negative regulation of heart looping GO:1901208 1 0.134
positive regulation of cellular component biogenesis GO:0044089 94 0.133
metanephric epithelium development GO:0072207 21 0.133
Mouse
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.132
his purkinje system cell differentiation GO:0060932 2 0.131
sinoatrial node cell differentiation GO:0060921 3 0.130
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.130
positive regulation of nervous system development GO:0051962 221 0.130
histone methylation GO:0016571 71 0.129
negative regulation of organelle organization GO:0010639 90 0.129
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.129
proteasomal protein catabolic process GO:0010498 98 0.127
chromatin mediated maintenance of transcription GO:0048096 2 0.127
mesodermal cell differentiation GO:0048333 22 0.127
positive regulation of skeletal muscle fiber differentiation GO:1902811 2 0.127
trophectodermal cell proliferation GO:0001834 2 0.126
limb bud formation GO:0060174 10 0.126
metanephros morphogenesis GO:0003338 24 0.126
peptidyl amino acid modification GO:0018193 336 0.125
cardiac atrium development GO:0003230 24 0.125
retina morphogenesis in camera type eye GO:0060042 45 0.125
cardiac muscle cell fate commitment GO:0060923 6 0.125
positive regulation of neuron differentiation GO:0045666 141 0.125
cell differentiation involved in kidney development GO:0061005 33 0.125
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.124
negative regulation of cell fate commitment GO:0010454 8 0.124
dna dealkylation GO:0035510 11 0.124
somatic diversification of immunoglobulins GO:0016445 43 0.123
positive regulation of muscle cell differentiation GO:0051149 39 0.122
regulation of smoothened signaling pathway GO:0008589 58 0.122
primary prostatic bud elongation GO:0060516 2 0.122
negative regulation of cell development GO:0010721 169 0.122
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.121
kidney development GO:0001822 213 0.121
Mouse
regulation of heart morphogenesis GO:2000826 22 0.120
Human
developmental growth involved in morphogenesis GO:0060560 138 0.120
Mouse

Pou5f1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.609
disease of anatomical entity DOID:7 0 0.609
nervous system disease DOID:863 0 0.609
eye and adnexa disease DOID:1492 0 0.173
eye disease DOID:5614 0 0.173