Mus musculus

232 known processes

Prkcd

protein kinase C, delta

(Aliases: PKCdelta,PKC[d],Pkcd,AI385711,D14Ertd420e)

Prkcd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune response activating signal transduction GO:0002757 116 0.935
interleukin 5 secretion GO:0072603 2 0.918
Mouse
amine metabolic process GO:0009308 45 0.896
Human
activation of immune response GO:0002253 138 0.886
regulation of lymphocyte proliferation GO:0050670 117 0.852
Mouse
lymphocyte proliferation GO:0046651 164 0.839
interleukin 10 secretion GO:0072608 4 0.836
Mouse
toll like receptor signaling pathway GO:0002224 38 0.824
regulation of cellular amine metabolic process GO:0033238 20 0.822
Human
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.816
myeloid cell differentiation GO:0030099 233 0.806
positive regulation of rac gtpase activity GO:0032855 14 0.745
ras protein signal transduction GO:0007265 77 0.730
cellular amine metabolic process GO:0044106 44 0.688
Human
regulation of rho gtpase activity GO:0032319 58 0.686
cellular amino acid metabolic process GO:0006520 103 0.664
negative regulation of cell activation GO:0050866 111 0.652
cellular ketone metabolic process GO:0042180 84 0.645
epidermis development GO:0008544 187 0.637
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.632
regulation of kinase activity GO:0043549 249 0.626
Human Rat
small gtpase mediated signal transduction GO:0007264 97 0.611
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.610
cell adhesion GO:0007155 329 0.608
negative regulation of cell proliferation GO:0008285 296 0.599
hemostasis GO:0007599 78 0.599
immune response regulating signaling pathway GO:0002764 125 0.592
negative regulation of b cell proliferation GO:0030889 13 0.586
b cell receptor signaling pathway GO:0050853 20 0.582
positive regulation of rho gtpase activity GO:0032321 41 0.580
cell chemotaxis GO:0060326 81 0.575
b cell proliferation GO:0042100 53 0.551
regulation of leukocyte proliferation GO:0070663 121 0.549
Mouse
glial cell apoptotic process GO:0034349 3 0.524
Human
positive regulation of protein modification process GO:0031401 299 0.513
Human Mouse Rat
peptidyl amino acid modification GO:0018193 336 0.509
apoptotic signaling pathway GO:0097190 306 0.506
regulation of ion transport GO:0043269 215 0.505
Human Mouse
cellular response to biotic stimulus GO:0071216 92 0.495
negative regulation of homeostatic process GO:0032845 71 0.476
regulation of hydrolase activity GO:0051336 246 0.466
Mouse
purine nucleotide catabolic process GO:0006195 211 0.461
Mouse
innate immune response activating signal transduction GO:0002758 50 0.447
negative regulation of lymphocyte activation GO:0051250 91 0.439
regulation of cell adhesion GO:0030155 154 0.438
cellular chemical homeostasis GO:0055082 215 0.430
positive regulation of gtp catabolic process GO:0033126 85 0.426
Mouse
glycosyl compound metabolic process GO:1901657 246 0.416
Mouse
regulation of transferase activity GO:0051338 263 0.415
Human Rat
lymphocyte differentiation GO:0030098 242 0.414
Mouse
response to organic cyclic compound GO:0014070 198 0.413
Mouse Rat
ion transmembrane transport GO:0034220 361 0.411
positive regulation of cellular catabolic process GO:0031331 148 0.411
Human Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.411
leukocyte activation involved in immune response GO:0002366 126 0.404
Mouse
t cell differentiation GO:0030217 174 0.400
Mouse
t cell differentiation in thymus GO:0033077 77 0.387
negative regulation of protein metabolic process GO:0051248 282 0.384
positive regulation of protein phosphorylation GO:0001934 242 0.375
Mouse Rat
regulation of interleukin 5 secretion GO:2000662 2 0.374
Mouse
negative regulation of protein modification process GO:0031400 163 0.370
skin development GO:0043588 220 0.369
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.368
Mouse
calcium ion transport into cytosol GO:0060402 48 0.366
regulation of cellular catabolic process GO:0031329 242 0.365
Human Yeast Mouse
response to peptide GO:1901652 136 0.365
maintenance of location GO:0051235 89 0.364
mammary gland epithelium development GO:0061180 65 0.362
negative regulation of cellular amine metabolic process GO:0033239 1 0.359
negative regulation of immune system process GO:0002683 209 0.359
rho protein signal transduction GO:0007266 32 0.350
t cell receptor signaling pathway GO:0050852 46 0.349
sequestering of calcium ion GO:0051208 18 0.340
nucleoside catabolic process GO:0009164 206 0.339
Mouse
defense response to other organism GO:0098542 197 0.339
regulation of interleukin 13 secretion GO:2000665 2 0.338
Mouse
metal ion homeostasis GO:0055065 189 0.337
regulation of interleukin 10 secretion GO:2001179 4 0.336
Mouse
endocytosis GO:0006897 168 0.335
macromolecule catabolic process GO:0009057 281 0.334
Yeast Mouse
cellular metal ion homeostasis GO:0006875 151 0.330
guanosine containing compound metabolic process GO:1901068 144 0.326
Mouse
germ cell development GO:0007281 185 0.326
Mouse
regulation of map kinase activity GO:0043405 120 0.324
Human Rat
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.322
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.317
Mouse
activation of innate immune response GO:0002218 56 0.316
regulation of protein serine threonine kinase activity GO:0071900 157 0.310
Human Rat
calcium ion transport GO:0006816 159 0.309
organonitrogen compound catabolic process GO:1901565 264 0.306
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.299
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.299
Mouse
myeloid leukocyte activation GO:0002274 83 0.297
Human
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.296
sensory organ morphogenesis GO:0090596 242 0.294
Mouse
regulation of protein kinase activity GO:0045859 232 0.293
Human Rat
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.292
Mouse
regulation of body fluid levels GO:0050878 162 0.290
antigen receptor mediated signaling pathway GO:0050851 64 0.280
leukocyte proliferation GO:0070661 172 0.276
regulation of proteolysis GO:0030162 164 0.274
Mouse
gtp catabolic process GO:0006184 143 0.272
Mouse
interleukin 12 production GO:0032615 32 0.271
response to organonitrogen compound GO:0010243 246 0.267
i kappab kinase nf kappab signaling GO:0007249 85 0.266
positive regulation of gtpase activity GO:0043547 85 0.265
Mouse
regulation of protein catabolic process GO:0042176 108 0.263
Mouse
cellular ion homeostasis GO:0006873 165 0.258
regulation of secretion GO:0051046 274 0.257
Mouse
b cell homeostasis GO:0001782 34 0.257
organic cyclic compound catabolic process GO:1901361 295 0.249
Yeast Mouse
macromolecule methylation GO:0043414 120 0.247
alpha beta t cell differentiation GO:0046632 69 0.246
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.244
Mouse
dephosphorylation GO:0016311 129 0.243
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.240
lateral inhibition GO:0046331 1 0.239
regulation of gtp catabolic process GO:0033124 113 0.239
Mouse
innate immune response GO:0045087 157 0.236
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.234
Mouse
divalent metal ion transport GO:0070838 172 0.234
inflammatory response GO:0006954 244 0.233
Mouse
negative regulation of t cell activation GO:0050868 65 0.229
regulation of cellular ketone metabolic process GO:0010565 66 0.227
positive regulation of mapk cascade GO:0043410 170 0.227
Rat
positive regulation of defense response GO:0031349 124 0.227
transmembrane transport GO:0055085 412 0.226
Mouse
positive regulation of programmed cell death GO:0043068 218 0.221
single organism cell adhesion GO:0098602 156 0.219
ribonucleotide catabolic process GO:0009261 208 0.218
Mouse
extracellular structure organization GO:0043062 148 0.217
regulation of t cell activation GO:0050863 170 0.213
Mouse
gland development GO:0048732 330 0.210
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.210
Mouse
leukocyte migration GO:0050900 124 0.209
positive regulation of apoptotic process GO:0043065 217 0.209
regulation of cytokine production GO:0001817 266 0.208
Mouse
b cell activation GO:0042113 161 0.207
ribose phosphate metabolic process GO:0019693 291 0.207
Mouse
regulation of mapk cascade GO:0043408 248 0.207
Human Rat
regulation of b cell activation GO:0050864 81 0.205
actin filament polymerization GO:0030041 44 0.204
homeostasis of number of cells GO:0048872 210 0.200
response to molecule of bacterial origin GO:0002237 143 0.199
lymphocyte homeostasis GO:0002260 64 0.196
cellular response to lipopolysaccharide GO:0071222 77 0.192
interferon beta biosynthetic process GO:0045350 4 0.192
interleukin 13 secretion GO:0072611 2 0.190
Mouse
purine nucleoside metabolic process GO:0042278 241 0.188
Mouse
coagulation GO:0050817 78 0.188
regulation of leukocyte differentiation GO:1902105 159 0.187
Mouse
regulation of protein localization GO:0032880 231 0.185
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.185
Human
regulation of cellular component biogenesis GO:0044087 181 0.184
cation transport GO:0006812 399 0.184
Mouse
divalent inorganic cation transport GO:0072511 178 0.183
regulation of b cell proliferation GO:0030888 39 0.182
ribonucleotide metabolic process GO:0009259 291 0.181
Mouse
immune effector process GO:0002252 321 0.180
regulation of metal ion transport GO:0010959 106 0.179
Mouse
gtp metabolic process GO:0046039 144 0.179
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.179
cellular divalent inorganic cation homeostasis GO:0072503 127 0.177
purine nucleotide metabolic process GO:0006163 302 0.176
Mouse
response to peptide hormone GO:0043434 127 0.173
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.171
Mouse
cellular response to ethanol GO:0071361 3 0.169
lipid localization GO:0010876 126 0.169
Human
positive regulation of nucleotide catabolic process GO:0030813 88 0.169
Mouse
positive regulation of interleukin 12 production GO:0032735 21 0.168
leukocyte differentiation GO:0002521 342 0.168
Mouse
negative regulation of kinase activity GO:0033673 81 0.167
Human
regulation of ras gtpase activity GO:0032318 88 0.166
Mouse
negative regulation of interleukin 10 secretion GO:2001180 2 0.164
axonogenesis GO:0007409 274 0.163
regulation of innate immune response GO:0045088 91 0.162
purine ribonucleotide metabolic process GO:0009150 290 0.162
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.161
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.161
Mouse
negative regulation of molecular function GO:0044092 258 0.159
Human Mouse
regulation of cell cycle GO:0051726 281 0.159
negative regulation of cellular protein metabolic process GO:0032269 247 0.159
adaptive immune response GO:0002250 155 0.158
cellular calcium ion homeostasis GO:0006874 119 0.153
purine nucleoside triphosphate catabolic process GO:0009146 203 0.152
Mouse
heterocycle catabolic process GO:0046700 280 0.152
Yeast Mouse
sequestering of metal ion GO:0051238 19 0.152
regulation of membrane potential GO:0042391 192 0.151
cation homeostasis GO:0055080 212 0.149
regulation of response to wounding GO:1903034 189 0.148
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.148
Mouse
ribonucleoside metabolic process GO:0009119 245 0.147
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.147
Mouse
leukocyte homeostasis GO:0001776 79 0.146
aromatic compound catabolic process GO:0019439 286 0.146
Yeast Mouse
germinal center formation GO:0002467 16 0.145
regulation of vesicle mediated transport GO:0060627 139 0.144
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.142
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.141
purine nucleoside triphosphate metabolic process GO:0009144 226 0.141
Mouse
peptidyl serine phosphorylation GO:0018105 74 0.140
Mouse
regulation of cell activation GO:0050865 289 0.139
purine containing compound metabolic process GO:0072521 311 0.138
Mouse
extracellular matrix organization GO:0030198 147 0.138
ribonucleoside triphosphate catabolic process GO:0009203 199 0.137
Mouse
regulation of protein complex assembly GO:0043254 83 0.137
t cell activation GO:0042110 289 0.133
Mouse
myeloid dendritic cell differentiation GO:0043011 16 0.132
peptidyl tyrosine modification GO:0018212 145 0.132
positive regulation of cytokine biosynthetic process GO:0042108 40 0.131
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.130
Mouse
ribonucleoside catabolic process GO:0042454 206 0.129
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.129
keratinocyte differentiation GO:0030216 48 0.129
positive regulation of cell migration GO:0030335 109 0.128
lipid transport GO:0006869 98 0.126
Human
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.124
Rat
circulatory system process GO:0003013 197 0.124
regulation of alpha beta t cell proliferation GO:0046640 18 0.124
marginal zone b cell differentiation GO:0002315 2 0.123
b cell mediated immunity GO:0019724 71 0.122
cytosolic calcium ion homeostasis GO:0051480 70 0.122
regulation of cell motility GO:2000145 236 0.121
regulation of cellular component size GO:0032535 121 0.119
regulation of alpha beta t cell differentiation GO:0046637 35 0.119
Mouse
protein autophosphorylation GO:0046777 61 0.118
Rat
cellular homeostasis GO:0019725 240 0.117
cell substrate adhesion GO:0031589 130 0.117
regulation of purine nucleotide metabolic process GO:1900542 169 0.116
Mouse
regulation of defense response GO:0031347 233 0.116
positive regulation of cell death GO:0010942 224 0.114
multicellular organismal homeostasis GO:0048871 164 0.113
anion transport GO:0006820 177 0.113
Human Rat
leukocyte chemotaxis GO:0030595 69 0.113
cellular response to molecule of bacterial origin GO:0071219 83 0.112
heart contraction GO:0060047 93 0.112
regulation of nucleotide catabolic process GO:0030811 122 0.112
Mouse
cytokine production GO:0001816 319 0.111
response to oxidative stress GO:0006979 123 0.111
Rat
positive regulation of map kinase activity GO:0043406 84 0.110
Rat
t cell activation involved in immune response GO:0002286 43 0.110
Mouse
alpha beta t cell activation GO:0046631 91 0.109
Mouse
calcium ion homeostasis GO:0055074 127 0.107
peptidyl serine modification GO:0018209 83 0.106
Mouse
response to inorganic substance GO:0010035 96 0.106
Rat
pattern recognition receptor signaling pathway GO:0002221 47 0.106
tissue remodeling GO:0048771 102 0.105
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.104
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 6 0.104
regulation of myeloid cell differentiation GO:0045637 96 0.103
cellular protein complex assembly GO:0043623 116 0.103
nuclear division GO:0000280 158 0.102
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.102
bone resorption GO:0045453 38 0.101
carboxylic acid transport GO:0046942 100 0.100
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.100
Mouse
positive regulation of cytokine production GO:0001819 174 0.100
Mouse
positive regulation of innate immune response GO:0045089 80 0.099
cell type specific apoptotic process GO:0097285 268 0.099
Human
regulation of neuron death GO:1901214 134 0.098
glycosyl compound catabolic process GO:1901658 206 0.098
Mouse
regulation of cell migration GO:0030334 219 0.098
regulation of nucleotide metabolic process GO:0006140 169 0.098
Mouse
cytoplasmic transport GO:0016482 234 0.097
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.097
negative regulation of cytokine production GO:0001818 84 0.096
regulation of secretion by cell GO:1903530 249 0.096
Mouse
organophosphate catabolic process GO:0046434 232 0.096
Human Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.096
Human
regulation of actin filament polymerization GO:0030833 38 0.095
regulation of transmembrane transport GO:0034762 128 0.095
positive regulation of organelle organization GO:0010638 128 0.094
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.094
release of sequestered calcium ion into cytosol GO:0051209 42 0.093
substrate adhesion dependent cell spreading GO:0034446 30 0.093
inorganic ion transmembrane transport GO:0098660 234 0.093
nitrogen compound transport GO:0071705 271 0.092
Rat
cellular response to cytokine stimulus GO:0071345 189 0.091
Mouse
leukocyte mediated immunity GO:0002443 174 0.090
nucleotide catabolic process GO:0009166 217 0.089
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.089
glucose metabolic process GO:0006006 92 0.089
Mouse
actin cytoskeleton organization GO:0030036 220 0.089
negative regulation of lymphocyte proliferation GO:0050672 45 0.089
lymphocyte activation involved in immune response GO:0002285 93 0.088
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.088
Mouse
calcium ion transmembrane transport GO:0070588 85 0.088
learning or memory GO:0007611 148 0.088
divalent inorganic cation homeostasis GO:0072507 138 0.087
cellular lipid metabolic process GO:0044255 323 0.087
Human
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.087
positive regulation of nucleotide metabolic process GO:0045981 114 0.086
Mouse
b cell activation involved in immune response GO:0002312 50 0.086
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.086
protein catabolic process GO:0030163 221 0.085
Mouse
regulation of zinc ion transmembrane transport GO:0071580 2 0.085
cognition GO:0050890 149 0.085
epithelial tube morphogenesis GO:0060562 303 0.085
regulation of hormone levels GO:0010817 211 0.085
regulation of lipid transport GO:0032368 36 0.084
Human
nucleoside phosphate catabolic process GO:1901292 222 0.083
Mouse
regulation of actin filament length GO:0030832 45 0.083
organelle fission GO:0048285 170 0.083
regulation of alpha beta t cell activation GO:0046634 53 0.083
Mouse
neuron apoptotic process GO:0051402 142 0.083
nucleoside phosphate metabolic process GO:0006753 338 0.082
Mouse
blood vessel morphogenesis GO:0048514 285 0.082
positive regulation of secretion by cell GO:1903532 114 0.081
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.080
response to lipopolysaccharide GO:0032496 128 0.080
myeloid leukocyte differentiation GO:0002573 119 0.080
single organismal cell cell adhesion GO:0016337 131 0.080
myeloid cell activation involved in immune response GO:0002275 34 0.079
positive regulation of cellular amine metabolic process GO:0033240 5 0.079
Human
regulation of organ morphogenesis GO:2000027 144 0.079
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.078
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.078
Mouse
epidermal growth factor receptor signaling pathway GO:0007173 28 0.078
angiogenesis GO:0001525 201 0.078
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.078
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.078
protein kinase b signaling GO:0043491 74 0.077
Mouse
glycerolipid metabolic process GO:0046486 122 0.076
regulation of hepatocyte proliferation GO:2000345 6 0.076
positive regulation of protein kinase activity GO:0045860 144 0.076
Rat
myeloid dendritic cell activation GO:0001773 25 0.076
response to radiation GO:0009314 165 0.075
forebrain development GO:0030900 302 0.075
regulation of b cell differentiation GO:0045577 23 0.075
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.073
wound healing GO:0042060 157 0.073
positive regulation of secretion GO:0051047 130 0.073
Mouse
protein methylation GO:0006479 81 0.073
phospholipid metabolic process GO:0006644 87 0.072
Human
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.072
cation transmembrane transport GO:0098655 266 0.072
phagocytosis GO:0006909 66 0.072
positive regulation of cell motility GO:2000147 116 0.072
skeletal muscle fiber development GO:0048741 58 0.071
cellular response to extracellular stimulus GO:0031668 81 0.071
Rat
epithelial cell proliferation GO:0050673 174 0.071
posttranscriptional regulation of gene expression GO:0010608 155 0.071
regulation of toll like receptor signaling pathway GO:0034121 20 0.071
regulation of lymphocyte activation GO:0051249 240 0.071
Mouse
b cell apoptotic process GO:0001783 19 0.071
cellular response to insulin stimulus GO:0032869 78 0.070
regulation of cell shape GO:0008360 39 0.070
nucleobase containing small molecule metabolic process GO:0055086 352 0.070
Mouse
cell division GO:0051301 120 0.070
regulation of nucleoside metabolic process GO:0009118 130 0.070
Mouse
myeloid leukocyte migration GO:0097529 57 0.070
negative regulation of phosphorus metabolic process GO:0010563 184 0.069
cytosolic calcium ion transport GO:0060401 48 0.069
ensheathment of neurons GO:0007272 76 0.069
Mouse
development of primary sexual characteristics GO:0045137 143 0.069
positive regulation of transferase activity GO:0051347 167 0.069
Rat
negative regulation of interleukin 13 secretion GO:2000666 1 0.068
axon guidance GO:0007411 141 0.068
synaptic transmission GO:0007268 329 0.068
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.067
regulation of insulin receptor signaling pathway GO:0046626 21 0.067
locomotory behavior GO:0007626 195 0.067
regulation of calcium ion transport GO:0051924 69 0.067
positive regulation of apoptotic signaling pathway GO:2001235 95 0.067
activation of rac gtpase activity GO:0032863 2 0.066
humoral immune response GO:0006959 57 0.066
cellular response to oxidative stress GO:0034599 76 0.066
defense response to protozoan GO:0042832 25 0.066
immunoglobulin secretion GO:0048305 17 0.065
necroptotic process GO:0070266 21 0.065
nucleotide metabolic process GO:0009117 332 0.065
Mouse
regulation of binding GO:0051098 111 0.065
cellular response to dna damage stimulus GO:0006974 207 0.065
Human
negative regulation of tumor necrosis factor biosynthetic process GO:0042536 1 0.065
intrinsic apoptotic signaling pathway GO:0097193 132 0.064
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.064
positive regulation of cell development GO:0010720 237 0.064
regulation of cytokine secretion involved in immune response GO:0002739 4 0.064
organic acid transport GO:0015849 101 0.064
Rat
positive regulation of kinase activity GO:0033674 155 0.063
Rat
digestive system development GO:0055123 200 0.063
amide transport GO:0042886 138 0.063
t helper cell differentiation GO:0042093 28 0.063
Mouse
ossification GO:0001503 216 0.062
Mouse
nucleocytoplasmic transport GO:0006913 139 0.062
cytokine biosynthetic process GO:0042089 68 0.062
Mouse
regulation of ion transmembrane transporter activity GO:0032412 54 0.062
circadian rhythm GO:0007623 114 0.062
odontogenesis GO:0042476 78 0.061
chromatin modification GO:0016568 187 0.061
regulation of anatomical structure size GO:0090066 178 0.061
histamine production involved in inflammatory response GO:0002349 1 0.061
regulation of organelle organization GO:0033043 289 0.061
covalent chromatin modification GO:0016569 163 0.061
positive regulation of leukocyte apoptotic process GO:2000108 21 0.060
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.060
regulation of neutrophil differentiation GO:0045658 2 0.060
regulation of reactive oxygen species metabolic process GO:2000377 40 0.060
Human
embryonic epithelial tube formation GO:0001838 130 0.059
negative regulation of interleukin 13 production GO:0032696 2 0.059
lipid biosynthetic process GO:0008610 179 0.059
Human
developmental programmed cell death GO:0010623 41 0.059
dendritic cell differentiation GO:0097028 26 0.059
positive regulation of homeostatic process GO:0032846 64 0.059
peptidyl tyrosine phosphorylation GO:0018108 143 0.059
spleen development GO:0048536 39 0.058
negative regulation of interleukin 5 secretion GO:2000663 1 0.058
female gamete generation GO:0007292 74 0.058
regulation of rho protein signal transduction GO:0035023 71 0.058
peptidyl tyrosine dephosphorylation GO:0035335 23 0.058
neuron death GO:0070997 154 0.058
regulated secretory pathway GO:0045055 32 0.058
cellular response to peptide GO:1901653 92 0.058
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.057
regulation of antimicrobial humoral response GO:0002759 3 0.057
organonitrogen compound biosynthetic process GO:1901566 192 0.057
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.056
Mouse
nik nf kappab signaling GO:0038061 14 0.056
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.056
positive regulation of ras gtpase activity GO:0032320 65 0.056
Mouse
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.056
inner ear receptor cell development GO:0060119 39 0.056
positive regulation of antimicrobial peptide production GO:0002225 1 0.055
cell matrix adhesion GO:0007160 68 0.055
establishment of protein localization to organelle GO:0072594 118 0.055
purine ribonucleoside catabolic process GO:0046130 205 0.055
Mouse
regulation of establishment of protein localization GO:0070201 181 0.054
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.054
intracellular protein transport GO:0006886 204 0.054
Mouse
hepaticobiliary system development GO:0061008 67 0.054
regulation of cysteine type endopeptidase activity GO:2000116 65 0.054
Mouse
regulation of actin polymerization or depolymerization GO:0008064 45 0.053
pallium development GO:0021543 120 0.053
granulocyte chemotaxis GO:0071621 39 0.053
nucleoside triphosphate catabolic process GO:0009143 205 0.053
Mouse
regulation of transporter activity GO:0032409 57 0.053
Human
regulation of t cell differentiation GO:0045580 83 0.053
Mouse
protein alkylation GO:0008213 81 0.052
dendrite development GO:0016358 115 0.052
activation of mapk activity GO:0000187 59 0.052
negative regulation of leukocyte proliferation GO:0070664 46 0.052
establishment of tissue polarity GO:0007164 28 0.051
positive regulation of intracellular transport GO:0032388 70 0.051
Mouse
negative regulation of regulatory t cell differentiation GO:0045590 2 0.051
forebrain cell migration GO:0021885 58 0.051
positive regulation of leukocyte proliferation GO:0070665 73 0.051
Mouse
positive regulation of b cell proliferation GO:0030890 24 0.051
cellular response to lipid GO:0071396 145 0.050
regulation of neuron differentiation GO:0045664 281 0.050
Mouse
gonad development GO:0008406 141 0.050
hormone secretion GO:0046879 128 0.050
organic hydroxy compound metabolic process GO:1901615 203 0.050
Human
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.050
neutrophil chemotaxis GO:0030593 36 0.050
genetic imprinting GO:0071514 27 0.050
positive regulation of chemotaxis GO:0050921 38 0.050
mature b cell differentiation involved in immune response GO:0002313 9 0.050
regulation of homotypic cell cell adhesion GO:0034110 13 0.050
dna modification GO:0006304 50 0.049
l amino acid transport GO:0015807 32 0.049
regulation of ion transmembrane transport GO:0034765 119 0.049
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.049
lymphocyte apoptotic process GO:0070227 54 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
Mouse
regulation of interleukin 10 biosynthetic process GO:0045074 1 0.048
response to growth factor GO:0070848 198 0.048
Mouse
protein import into nucleus GO:0006606 95 0.048
dna methylation GO:0006306 43 0.048
positive regulation of protein catabolic process GO:0045732 60 0.048
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.048
Mouse
negative regulation of mast cell proliferation GO:0070667 1 0.048
blood circulation GO:0008015 195 0.048
peptidyl lysine modification GO:0018205 77 0.048
regulation of cell substrate adhesion GO:0010810 73 0.047
cellular amide metabolic process GO:0043603 58 0.047
Human
molting cycle GO:0042303 90 0.047
Mouse
multicellular organism growth GO:0035264 161 0.047
compound eye development GO:0048749 1 0.047
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.047
carbohydrate metabolic process GO:0005975 230 0.047
Mouse
positive regulation of osteoclast differentiation GO:0045672 15 0.047
regulation of cytokine production involved in immune response GO:0002718 26 0.047
Mouse
regulation of translation GO:0006417 71 0.046

Prkcd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.167
Human
musculoskeletal system disease DOID:17 0 0.167
connective tissue disease DOID:65 0 0.167
primary immunodeficiency disease DOID:612 0 0.164
Human
immune system disease DOID:2914 0 0.164
Human
b cell deficiency DOID:2115 0 0.164
Human
disease of metabolism DOID:0014667 0 0.116
bone disease DOID:0080001 0 0.095
nervous system disease DOID:863 0 0.094
bone inflammation disease DOID:3342 0 0.093
arthritis DOID:848 0 0.093
blood protein disease DOID:620 0 0.092
Human
agammaglobulinemia DOID:2583 0 0.092
Human
hematopoietic system disease DOID:74 0 0.092
Human
hypersensitivity reaction disease DOID:0060056 0 0.064
hypersensitivity reaction type ii disease DOID:417 0 0.064