Mus musculus

81 known processes

Prrx1

paired related homeobox 1

(Aliases: AI843499,AA755424,K-2,AI385634,Pmx1,A230024N07Rik,Prx1,mHox)

Prrx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
skeletal system development GO:0001501 356 1.000
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
auditory receptor cell fate determination GO:0042668 3 1.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 1.000
stem cell differentiation GO:0048863 268 1.000
Mouse
mesenchyme development GO:0060485 152 1.000
Mouse
embryonic skeletal system development GO:0048706 120 1.000
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 1.000
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 1.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 1.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 1.000
embryonic skeletal system morphogenesis GO:0048704 91 1.000
chondrocyte development GO:0002063 24 1.000
neural tube closure GO:0001843 90 1.000
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 1.000
trachea formation GO:0060440 3 1.000
regionalization GO:0003002 337 1.000
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 1.000
embryonic organ morphogenesis GO:0048562 276 1.000
cell proliferation in hindbrain GO:0021534 10 1.000
metanephric capsule specification GO:0072267 1 1.000
cartilage condensation GO:0001502 18 1.000
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 1.000
embryonic nail plate morphogenesis GO:0035880 3 1.000
embryonic heart tube formation GO:0003144 1 1.000
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 1.000
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 1.000
appendage morphogenesis GO:0035107 149 1.000
bone morphogenesis GO:0060349 78 1.000
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.999
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.999
stem cell development GO:0048864 219 0.999
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.999
regulation of endodermal cell differentiation GO:1903224 2 0.999
negative regulation of gastrulation GO:2000542 3 0.999
pyramidal neuron migration GO:0021852 1 0.999
telencephalon development GO:0021537 186 0.999
chondrocyte differentiation GO:0002062 72 0.999
negative regulation of cell fate specification GO:0009996 4 0.999
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.999
trachea cartilage morphogenesis GO:0060535 4 0.999
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.999
endodermal cell fate commitment GO:0001711 12 0.999
ear morphogenesis GO:0042471 118 0.999
cartilage development GO:0051216 140 0.999
axonogenesis involved in innervation GO:0060385 5 0.999
somitogenesis GO:0001756 69 0.999
cerebellar granule cell precursor proliferation GO:0021930 10 0.999
sinoatrial node cell differentiation GO:0060921 3 0.999
globus pallidus development GO:0021759 2 0.999
skeletal system morphogenesis GO:0048705 203 0.999
primary prostatic bud elongation GO:0060516 2 0.999
branching morphogenesis of an epithelial tube GO:0048754 159 0.998
cartilage morphogenesis GO:0060536 11 0.998
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.998
tendon cell differentiation GO:0035990 4 0.998
cerebral cortex tangential migration GO:0021800 7 0.998
noradrenergic neuron differentiation GO:0003357 6 0.998
Mouse
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.998
appendage development GO:0048736 166 0.998
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.998
endocardial cushion formation GO:0003272 13 0.998
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.998
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.998
renal vesicle induction GO:0072034 3 0.997
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.997
embryonic skeletal joint morphogenesis GO:0060272 11 0.997
epithelial tube morphogenesis GO:0060562 303 0.997
ear development GO:0043583 200 0.997
branching involved in ureteric bud morphogenesis GO:0001658 56 0.997
morphogenesis of a branching epithelium GO:0061138 193 0.997
limb development GO:0060173 166 0.997
endodermal cell fate specification GO:0001714 4 0.997
positive regulation of stem cell proliferation GO:2000648 59 0.997
hindbrain tangential cell migration GO:0021934 2 0.997
Mouse
astrocyte fate commitment GO:0060018 4 0.997
negative regulation of neuron differentiation GO:0045665 101 0.997
Mouse
neural tube formation GO:0001841 108 0.997
axial mesodermal cell fate commitment GO:0048322 1 0.996
bmp signaling pathway involved in heart development GO:0061312 2 0.996
regulation of cartilage development GO:0061035 44 0.996
negative regulation of endodermal cell differentiation GO:1903225 1 0.996
regulation of astrocyte differentiation GO:0048710 20 0.996
cranial suture morphogenesis GO:0060363 8 0.996
regulation of endodermal cell fate specification GO:0042663 2 0.996
embryonic viscerocranium morphogenesis GO:0048703 8 0.996
regulation of neuron projection development GO:0010975 169 0.995
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.995
negative regulation of astrocyte differentiation GO:0048712 10 0.995
pituitary gland development GO:0021983 38 0.995
tendon formation GO:0035992 4 0.995
otic placode formation GO:0043049 1 0.995
neural crest cell fate commitment GO:0014034 1 0.995
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.995
limb morphogenesis GO:0035108 149 0.995
aorta morphogenesis GO:0035909 22 0.995
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.994
tube formation GO:0035148 140 0.994
cerebral cortex neuron differentiation GO:0021895 19 0.994
embryonic camera type eye development GO:0031076 36 0.994
mesenchymal cell development GO:0014031 93 0.994
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.994
ureteric bud development GO:0001657 94 0.994
morphogenesis of a branching structure GO:0001763 203 0.994
osteoblast development GO:0002076 17 0.993
closure of optic fissure GO:0061386 2 0.993
heart valve morphogenesis GO:0003179 21 0.993
bone development GO:0060348 120 0.993
palate development GO:0060021 76 0.993
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.993
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.993
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.993
ventricular zone neuroblast division GO:0021847 3 0.993
neural crest cell migration GO:0001755 32 0.993
Mouse
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.993
olfactory bulb interneuron development GO:0021891 7 0.992
parasympathetic nervous system development GO:0048486 19 0.992
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.992
trophectodermal cellular morphogenesis GO:0001831 3 0.992
cardiac endothelial cell differentiation GO:0003348 4 0.991
retinal bipolar neuron differentiation GO:0060040 5 0.991
neuron projection guidance GO:0097485 141 0.991
Mouse
mammary placode formation GO:0060596 4 0.991
endochondral bone morphogenesis GO:0060350 50 0.991
mammary gland bud morphogenesis GO:0060648 4 0.990
determination of heart left right asymmetry GO:0061371 48 0.990
cell proliferation in midbrain GO:0033278 2 0.990
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.989
olfactory lobe development GO:0021988 32 0.989
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.989
negative regulation of epithelial cell proliferation GO:0050680 64 0.988
mammary gland duct morphogenesis GO:0060603 38 0.988
sensory organ morphogenesis GO:0090596 242 0.988
inner ear morphogenesis GO:0042472 101 0.988
pancreatic pp cell fate commitment GO:0003329 2 0.987
primary neural tube formation GO:0014020 95 0.987
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.986
specification of organ position GO:0010159 3 0.986
telencephalon regionalization GO:0021978 14 0.986
metanephric nephron tubule formation GO:0072289 4 0.986
blood vessel morphogenesis GO:0048514 285 0.985
mesenchymal cell differentiation GO:0048762 107 0.985
Mouse
neural crest formation GO:0014029 2 0.985
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.985
forebrain generation of neurons GO:0021872 63 0.985
anterior commissure morphogenesis GO:0021960 6 0.985
stem cell maintenance GO:0019827 130 0.984
pallium development GO:0021543 120 0.984
mesonephros development GO:0001823 97 0.984
semicircular canal formation GO:0060876 1 0.983
lung development GO:0030324 164 0.983
corticotropin hormone secreting cell differentiation GO:0060128 3 0.983
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.983
gastrulation GO:0007369 116 0.983
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.983
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.982
regulation of neuron maturation GO:0014041 5 0.982
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.982
spinal cord motor neuron differentiation GO:0021522 35 0.981
Mouse
lateral mesodermal cell fate specification GO:0048377 2 0.980
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.979
negative regulation of neuron projection development GO:0010977 50 0.979
diencephalon development GO:0021536 63 0.979
cell proliferation in external granule layer GO:0021924 10 0.979
regulation of smoothened signaling pathway GO:0008589 58 0.978
epithelial to mesenchymal transition GO:0001837 47 0.978
muscle cell proliferation GO:0033002 52 0.977
regulation of bmp signaling pathway GO:0030510 60 0.977
heart field specification GO:0003128 6 0.977
negative regulation of axon extension GO:0030517 19 0.977
efferent axon development in a lateral line nerve GO:0048894 1 0.977
Mouse
kidney morphogenesis GO:0060993 83 0.976
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.976
respiratory system development GO:0060541 190 0.975
Mouse
odontogenesis GO:0042476 78 0.974
negative regulation of stem cell maintenance GO:1902455 4 0.974
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.974
negative regulation of chondrocyte differentiation GO:0032331 13 0.973
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.973
roof plate formation GO:0021509 1 0.973
forebrain neuron differentiation GO:0021879 52 0.973
regulation of skeletal muscle cell differentiation GO:2001014 11 0.972
frontal suture morphogenesis GO:0060364 2 0.972
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.972
activation of meiosis GO:0090427 4 0.972
forebrain cell migration GO:0021885 58 0.972
ascending aorta morphogenesis GO:0035910 3 0.972
chemotaxis GO:0006935 247 0.971
Mouse
negative regulation of glial cell differentiation GO:0045686 21 0.970
telencephalon cell migration GO:0022029 55 0.970
middle ear morphogenesis GO:0042474 23 0.970
chondroblast differentiation GO:0060591 2 0.970
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.970
renal system development GO:0072001 225 0.969
stem cell proliferation GO:0072089 117 0.969
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.969
connective tissue development GO:0061448 179 0.969
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.968
craniofacial suture morphogenesis GO:0097094 10 0.968
cell fate specification GO:0001708 72 0.968
positive regulation of transcription by glucose GO:0046016 3 0.967
floor plate morphogenesis GO:0033505 3 0.967
embryonic epithelial tube formation GO:0001838 130 0.966
rhombomere 3 morphogenesis GO:0021658 2 0.965
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.965
rhombomere 2 development GO:0021568 2 0.965
positive regulation of cartilage development GO:0061036 18 0.965
regulation of cardiac muscle tissue development GO:0055024 31 0.962
morphogenesis of embryonic epithelium GO:0016331 159 0.962
formation of primary germ layer GO:0001704 77 0.961
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.961
branch elongation involved in ureteric bud branching GO:0060681 3 0.961
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 9 0.960
establishment of neuroblast polarity GO:0045200 1 0.960
regulation of organ morphogenesis GO:2000027 144 0.960
prostate gland morphogenesis GO:0060512 32 0.960
branching involved in prostate gland morphogenesis GO:0060442 15 0.959
digestive system development GO:0055123 200 0.959
melanocyte differentiation GO:0030318 25 0.958
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.958
inner cell mass cellular morphogenesis GO:0001828 1 0.958
regulation of odontogenesis GO:0042481 18 0.958
cardiac septum development GO:0003279 59 0.957
cardiac muscle cell differentiation GO:0055007 69 0.957
cardiac left ventricle formation GO:0003218 1 0.956
positive regulation of tendon cell differentiation GO:2001051 1 0.956
axon guidance GO:0007411 141 0.956
Mouse
regulation of glial cell differentiation GO:0045685 41 0.954
vascular wound healing GO:0061042 3 0.954
embryonic genitalia morphogenesis GO:0030538 4 0.954
brain morphogenesis GO:0048854 32 0.952
carbon catabolite repression of transcription GO:0045013 1 0.951
axis elongation involved in somitogenesis GO:0090245 4 0.951
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.951
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.950
hindbrain development GO:0030902 128 0.950
Mouse
neural crest cell development GO:0014032 48 0.950
Mouse
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.950
negative regulation of endodermal cell fate specification GO:0042664 1 0.950
metanephric mesenchyme morphogenesis GO:0072133 4 0.949
sympathetic ganglion development GO:0061549 9 0.949
Mouse
cardiac chamber development GO:0003205 108 0.948
positive regulation of dna templated transcription elongation GO:0032786 2 0.948
cardiogenic plate morphogenesis GO:0003142 1 0.948
embryonic limb morphogenesis GO:0030326 126 0.947
central nervous system neuron development GO:0021954 67 0.946
Mouse
prostate gland stromal morphogenesis GO:0060741 2 0.945
regulation of heart morphogenesis GO:2000826 22 0.945
cardiac muscle cell development GO:0055013 39 0.945
his purkinje system cell differentiation GO:0060932 2 0.944
kidney development GO:0001822 213 0.942
embryonic forelimb morphogenesis GO:0035115 32 0.941
embryonic skeletal joint development GO:0072498 13 0.941
submandibular salivary gland formation GO:0060661 1 0.939
neuron projection extension GO:1990138 64 0.939
epithelial cell proliferation GO:0050673 174 0.939
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.938
cardiac epithelial to mesenchymal transition GO:0060317 18 0.937
forebrain development GO:0030900 302 0.937
salivary gland morphogenesis GO:0007435 33 0.937
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.936
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.935
negative regulation of branching involved in ureteric bud morphogenesis GO:0090191 4 0.934
midbrain hindbrain boundary maturation GO:0021732 1 0.933
regulation of tongue muscle cell differentiation GO:2001035 2 0.933
ossification GO:0001503 216 0.932
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.931
cellular response to bmp stimulus GO:0071773 14 0.931
Mouse
mesenchymal cell proliferation GO:0010463 44 0.929
cellular response to lipid GO:0071396 145 0.929
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.928
negative regulation of prostatic bud formation GO:0060686 4 0.927
cell migration involved in gastrulation GO:0042074 13 0.926
mesoderm formation GO:0001707 62 0.926
digestive tract development GO:0048565 190 0.924
atrioventricular bundle cell differentiation GO:0003167 1 0.923
inner ear receptor cell differentiation GO:0060113 61 0.922
cerebellum development GO:0021549 77 0.921
regulation of cellular amine metabolic process GO:0033238 20 0.920
semicircular canal development GO:0060872 9 0.920
nephron tubule morphogenesis GO:0072078 68 0.919
growth plate cartilage development GO:0003417 14 0.919
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.919
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.919
embryonic eye morphogenesis GO:0048048 29 0.918
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.918
specification of organ identity GO:0010092 30 0.917
autonomic nervous system development GO:0048483 43 0.914
Mouse
otic vesicle development GO:0071599 14 0.914
smooth muscle tissue development GO:0048745 22 0.914
bmp signaling pathway GO:0030509 93 0.913
mammary gland morphogenesis GO:0060443 54 0.913
growth plate cartilage chondrocyte growth GO:0003430 2 0.913
cardiac septum morphogenesis GO:0060411 46 0.913
axial mesodermal cell fate specification GO:0048327 1 0.913
mesenchymal cell proliferation involved in ureteric bud development GO:0072138 3 0.913
heart valve development GO:0003170 23 0.909
regulation of wnt signaling pathway GO:0030111 123 0.908
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.908
muscle fiber development GO:0048747 76 0.907
cell proliferation involved in heart morphogenesis GO:0061323 15 0.907
regulation of retina development in camera type eye GO:1902866 3 0.907
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.907
subpallium development GO:0021544 20 0.906
growth plate cartilage chondrocyte development GO:0003431 3 0.904
mitral valve development GO:0003174 4 0.904
somite development GO:0061053 81 0.904
compound eye development GO:0048749 1 0.904
cellular ketone metabolic process GO:0042180 84 0.904
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.903
positive regulation of axon extension GO:0045773 20 0.901
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.900
rhombomere 3 development GO:0021569 4 0.900
limbic system development GO:0021761 72 0.899
atrioventricular valve morphogenesis GO:0003181 13 0.898
axial mesodermal cell differentiation GO:0048321 1 0.897
cell proliferation in forebrain GO:0021846 30 0.897
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.896
cranial nerve formation GO:0021603 4 0.896
Mouse
oculomotor nerve formation GO:0021623 2 0.894
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.894
positive regulation of ureteric bud formation GO:0072107 3 0.894
olfactory bulb development GO:0021772 30 0.893
axial mesoderm formation GO:0048320 3 0.893
neural tube development GO:0021915 160 0.892
optic vesicle morphogenesis GO:0003404 2 0.892
semicircular canal morphogenesis GO:0048752 7 0.891
forelimb morphogenesis GO:0035136 40 0.891
regulation of vascular wound healing GO:0061043 2 0.890
muscle tissue development GO:0060537 308 0.889
Mouse
neural tube patterning GO:0021532 43 0.889
cochlea morphogenesis GO:0090103 22 0.887
regulation of heart looping GO:1901207 1 0.886
cellular response to retinoic acid GO:0071300 25 0.886
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.885
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.884
neural nucleus development GO:0048857 22 0.883
Mouse
embryonic digit morphogenesis GO:0042733 56 0.883
regulation of skeletal muscle fiber development GO:0048742 36 0.882
positive regulation of mapk cascade GO:0043410 170 0.882
mesoderm development GO:0007498 100 0.880
cardiac muscle tissue development GO:0048738 130 0.880
outer ear morphogenesis GO:0042473 5 0.878
regulation of epithelial cell proliferation GO:0050678 141 0.877
regulation of prostatic bud formation GO:0060685 6 0.877
apoptotic process involved in morphogenesis GO:0060561 25 0.877
ventricular cardiac muscle cell differentiation GO:0055012 17 0.877
primitive streak formation GO:0090009 10 0.876
axis elongation GO:0003401 30 0.875
odontogenesis of dentin containing tooth GO:0042475 66 0.874
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.873
regulation of mesodermal cell fate specification GO:0042661 5 0.873
cardiac right ventricle formation GO:0003219 3 0.873
medulla oblongata development GO:0021550 3 0.872
Mouse
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.871
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.870
endocardial cushion to mesenchymal transition GO:0090500 5 0.869
positive regulation of transcription via serum response element binding GO:0010735 1 0.868
tube closure GO:0060606 91 0.868
epithelial tube formation GO:0072175 130 0.867
subpallium neuron fate commitment GO:0060163 2 0.866
wound healing spreading of cells GO:0044319 8 0.865
negative regulation of cartilage development GO:0061037 17 0.864
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.864
regulation of myotube differentiation GO:0010830 62 0.864
skeletal muscle satellite cell differentiation GO:0014816 6 0.863
urogenital system development GO:0001655 261 0.862
central nervous system neuron differentiation GO:0021953 162 0.862
Mouse
glomerulus vasculature morphogenesis GO:0072103 6 0.862
negative regulation of cell development GO:0010721 169 0.862
Mouse
mammary gland bud formation GO:0060615 2 0.861
ureter smooth muscle development GO:0072191 5 0.861
embryonic appendage morphogenesis GO:0035113 126 0.859
mesonephric tubule morphogenesis GO:0072171 63 0.859
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.859
developmental maturation GO:0021700 193 0.856
cardiac chamber formation GO:0003207 10 0.854
left lung development GO:0060459 4 0.853
somite rostral caudal axis specification GO:0032525 13 0.852
lung induction GO:0060492 3 0.852
heart morphogenesis GO:0003007 178 0.851
mesoderm morphogenesis GO:0048332 64 0.851
cell differentiation in spinal cord GO:0021515 53 0.851
Mouse
lateral mesodermal cell differentiation GO:0048371 3 0.851
negative regulation of gliogenesis GO:0014014 23 0.850
cell proliferation involved in kidney development GO:0072111 14 0.850
endocardial cushion morphogenesis GO:0003203 18 0.849
hypophysis morphogenesis GO:0048850 3 0.848
positive regulation of cardioblast differentiation GO:0051891 3 0.848
tooth mineralization GO:0034505 9 0.845
nephric duct formation GO:0072179 4 0.842
regulation of osteoblast differentiation GO:0045667 67 0.841
granulosa cell differentiation GO:0060014 1 0.839
regulation of myoblast differentiation GO:0045661 29 0.836
positive regulation of epithelial cell proliferation GO:0050679 68 0.835
negative regulation of striated muscle cell differentiation GO:0051154 14 0.834
diencephalon morphogenesis GO:0048852 6 0.834
pattern specification involved in metanephros development GO:0072268 4 0.833
endochondral bone growth GO:0003416 19 0.833
positive regulation of cell development GO:0010720 237 0.831
Mouse
orbitofrontal cortex development GO:0021769 2 0.830
endodermal cell differentiation GO:0035987 14 0.830
regulation of cardiac chamber formation GO:1901210 1 0.830
ectodermal placode formation GO:0060788 16 0.830
lateral mesoderm formation GO:0048370 3 0.829
regulation of epithelial to mesenchymal transition GO:0010717 22 0.829
positive regulation of ossification GO:0045778 47 0.828
face morphogenesis GO:0060325 29 0.827
branching involved in labyrinthine layer morphogenesis GO:0060670 9 0.826
regulation of mapk cascade GO:0043408 248 0.825
midgut development GO:0007494 4 0.825
negative regulation of cell proliferation GO:0008285 296 0.825
Mouse
endocardial cell differentiation GO:0060956 4 0.824
trophectodermal cell differentiation GO:0001829 21 0.823
forebrain morphogenesis GO:0048853 17 0.823
mesodermal cell fate commitment GO:0001710 17 0.820
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.818
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.816
positive regulation of nervous system development GO:0051962 221 0.812
Mouse
cell maturation GO:0048469 127 0.811
positive regulation of vascular wound healing GO:0035470 1 0.811
negative regulation of epidermis development GO:0045683 9 0.810
epithelial cell development GO:0002064 159 0.809
forebrain regionalization GO:0021871 25 0.808
positive regulation of neuron differentiation GO:0045666 141 0.808
Mouse
preganglionic parasympathetic nervous system development GO:0021783 17 0.806
Mouse
positive regulation of odontogenesis GO:0042482 4 0.806
positive regulation of neuron projection regeneration GO:0070572 2 0.805
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.804
regulation of striated muscle cell differentiation GO:0051153 81 0.804
camera type eye development GO:0043010 266 0.803
astrocyte differentiation GO:0048708 43 0.801
cell migration involved in coronary angiogenesis GO:0060981 1 0.799
neural crest cell differentiation GO:0014033 54 0.797
Mouse
epithelial cell fate commitment GO:0072148 13 0.797
positive regulation of wnt signaling pathway GO:0030177 45 0.796
negative regulation of glomerular mesangial cell proliferation GO:0072125 1 0.795
skeletal muscle cell differentiation GO:0035914 66 0.795
Mouse
trabecula morphogenesis GO:0061383 40 0.790
ventricular cardiac myofibril assembly GO:0055005 3 0.790
cardiac chamber morphogenesis GO:0003206 93 0.788
cardiocyte differentiation GO:0035051 87 0.787
lung epithelial cell differentiation GO:0060487 29 0.786
developmental programmed cell death GO:0010623 41 0.785
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.785
cell migration involved in mesendoderm migration GO:0090134 1 0.785
striated muscle cell development GO:0055002 125 0.784
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.783
positive regulation of neuroblast proliferation GO:0002052 19 0.783
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.783
forebrain radial glial cell differentiation GO:0021861 4 0.782
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.782
endoderm formation GO:0001706 20 0.781
pancreatic a cell fate commitment GO:0003326 2 0.780
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.779
hindbrain morphogenesis GO:0021575 46 0.778
regulation of branch elongation involved in ureteric bud branching GO:0072095 3 0.778
atrial septum development GO:0003283 12 0.777
positive regulation of pigment cell differentiation GO:0050942 5 0.777
thalamus development GO:0021794 11 0.777
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.776
cell proliferation involved in mesonephros development GO:0061209 4 0.775
respiratory tube development GO:0030323 167 0.773
endothelial cell fate commitment GO:0060839 2 0.773
rhombomere morphogenesis GO:0021593 2 0.770
positive regulation of urine volume GO:0035810 6 0.770
embryonic neurocranium morphogenesis GO:0048702 3 0.769
glomerulus vasculature development GO:0072012 14 0.767
organ induction GO:0001759 21 0.767
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.765
neuron migration GO:0001764 122 0.765
Mouse
aorta development GO:0035904 23 0.765
cell migration in hindbrain GO:0021535 16 0.763
Mouse
hemangioblast cell differentiation GO:0060217 1 0.761
regulation of canonical wnt signaling pathway GO:0060828 82 0.761
positive regulation of hh target transcription factor activity GO:0007228 3 0.760
hindlimb morphogenesis GO:0035137 42 0.759
semicircular canal fusion GO:0060879 1 0.758
atrioventricular valve development GO:0003171 15 0.757
hippocampus development GO:0021766 52 0.756
endothelium development GO:0003158 45 0.753
oligodendrocyte differentiation GO:0048709 53 0.750
negative regulation of heart looping GO:1901208 1 0.750
trophoblast giant cell differentiation GO:0060707 15 0.748
regulation of auditory receptor cell differentiation GO:0045607 4 0.748
face development GO:0060324 38 0.748
cerebral cortex cell migration GO:0021795 44 0.747
striated muscle tissue development GO:0014706 293 0.744
Mouse
axonogenesis GO:0007409 274 0.743
Mouse
facial nerve morphogenesis GO:0021610 11 0.741
muscle cell fate commitment GO:0042693 11 0.741
otic vesicle morphogenesis GO:0071600 10 0.740
adenohypophysis development GO:0021984 14 0.740
sympathetic nervous system development GO:0048485 22 0.740
Mouse
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.740

Prrx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.927
musculoskeletal system disease DOID:17 0 0.927