Mus musculus

204 known processes

Rxra

retinoid X receptor alpha

(Aliases: 9530071D11Rik,Nr2b1,RXRalpha1)

Rxra biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cardioblast migration to the midline involved in heart field formation GO:0060975 1 1.000
clara cell differentiation GO:0060486 4 1.000
cardioblast migration GO:0003260 1 0.999
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.999
apoptotic process involved in mammary gland involution GO:0060057 4 0.998
gland development GO:0048732 330 0.997
cell migration to the midline involved in heart development GO:0003318 1 0.996
negative regulation of translational initiation GO:0045947 4 0.993
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.993
atrial septum primum morphogenesis GO:0003289 3 0.992
intracellular receptor signaling pathway GO:0030522 74 0.991
limb development GO:0060173 166 0.990
Mouse
pro t cell differentiation GO:0002572 3 0.988
positive regulation of cell death GO:0010942 224 0.988
Rat
cellular amide metabolic process GO:0043603 58 0.988
striated muscle cell proliferation GO:0014855 39 0.987
transcriptional activation by promoter enhancer looping GO:0071733 2 0.987
organ growth GO:0035265 117 0.986
cardiac muscle cell differentiation GO:0055007 69 0.985
regulation of cardioblast differentiation GO:0051890 3 0.985
wnt signaling pathway involved in kidney development GO:0061289 2 0.983
positive regulation of cardioblast differentiation GO:0051891 3 0.983
heart growth GO:0060419 45 0.983
regulation of cholesterol homeostasis GO:2000188 9 0.981
Mouse
ventricular septum morphogenesis GO:0060412 27 0.981
negative regulation of epithelial cell proliferation GO:0050680 64 0.980
gene looping GO:0090202 2 0.980
cell migration involved in heart formation GO:0060974 1 0.979
embryonic placenta development GO:0001892 98 0.978
Mouse
heart morphogenesis GO:0003007 178 0.977
muscle tissue development GO:0060537 308 0.977
stem cell maintenance GO:0019827 130 0.976
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.975
liver development GO:0001889 66 0.975
Rat
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.972
epithelial tube morphogenesis GO:0060562 303 0.972
cardiac right atrium morphogenesis GO:0003213 3 0.972
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.971
cardiac muscle tissue development GO:0048738 130 0.971
positive regulation of mammary gland involution GO:1903521 4 0.970
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.969
cardiac muscle cell proliferation GO:0060038 31 0.969
neuroblast differentiation GO:0014016 2 0.967
cardiac endothelial cell differentiation GO:0003348 4 0.966
lung lobe formation GO:0060464 1 0.966
regulation of organ morphogenesis GO:2000027 144 0.965
regulation of ureteric bud formation GO:0072106 3 0.963
kidney development GO:0001822 213 0.963
regulation of cell proliferation involved in mesonephros development GO:2000606 1 0.962
mesenchyme development GO:0060485 152 0.962
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.960
prostate gland morphogenesis GO:0060512 32 0.959
appendage development GO:0048736 166 0.959
Mouse
chondrocyte hypertrophy GO:0003415 4 0.957
placenta development GO:0001890 140 0.956
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.955
nephron tubule morphogenesis GO:0072078 68 0.954
regulation of fat cell differentiation GO:0045598 81 0.954
regulation of cellular amine metabolic process GO:0033238 20 0.953
negative regulation of cell proliferation GO:0008285 296 0.951
Rat
neuronal action potential GO:0019228 54 0.951
ventricular cardiac muscle cell differentiation GO:0055012 17 0.951
growth plate cartilage chondrocyte development GO:0003431 3 0.949
granulocyte differentiation GO:0030851 17 0.948
positive regulation of ureteric bud formation GO:0072107 3 0.947
fat cell differentiation GO:0045444 160 0.946
lung induction GO:0060492 3 0.945
glandular epithelial cell differentiation GO:0002067 38 0.945
telencephalon development GO:0021537 186 0.943
Mouse
stem cell differentiation GO:0048863 268 0.941
regulation of fatty acid metabolic process GO:0019217 28 0.941
Worm
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.938
positive regulation of heart growth GO:0060421 18 0.937
immune response activating signal transduction GO:0002757 116 0.937
response to leptin GO:0044321 7 0.934
anterior commissure morphogenesis GO:0021960 6 0.934
regulation of nitrogen cycle metabolic process GO:1903314 1 0.933
cell adhesion GO:0007155 329 0.933
cardiac septum development GO:0003279 59 0.930
circadian temperature homeostasis GO:0060086 2 0.930
release of cytochrome c from mitochondria GO:0001836 23 0.929
homeostasis of number of cells GO:0048872 210 0.928
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.928
cellular response to retinoic acid GO:0071300 25 0.923
Mouse
regulation of transcription involved in cell fate commitment GO:0060850 15 0.922
ureter maturation GO:0035799 4 0.921
embryonic appendage morphogenesis GO:0035113 126 0.921
definitive erythrocyte differentiation GO:0060318 7 0.920
negative regulation of leukocyte differentiation GO:1902106 51 0.919
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.919
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.918
nephric duct formation GO:0072179 4 0.917
mammary gland morphogenesis GO:0060443 54 0.917
positive regulation of steroid biosynthetic process GO:0010893 4 0.917
cellular lipid metabolic process GO:0044255 323 0.916
Worm
cardiac cell fate determination GO:0060913 2 0.916
peptidyl amino acid modification GO:0018193 336 0.915
oligodendrocyte differentiation GO:0048709 53 0.915
positive regulation of apoptotic signaling pathway GO:2001235 95 0.914
fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000699 1 0.914
morphogenesis of a branching epithelium GO:0061138 193 0.914
regulation of dna templated transcription in response to stress GO:0043620 9 0.913
immune response regulating signaling pathway GO:0002764 125 0.913
cytokine production GO:0001816 319 0.912
harderian gland development GO:0070384 2 0.911
positive regulation of growth GO:0045927 104 0.910
regulation of establishment of protein localization GO:0070201 181 0.910
forebrain development GO:0030900 302 0.909
Mouse
chondroblast differentiation GO:0060591 2 0.907
cell growth GO:0016049 130 0.906
megakaryocyte differentiation GO:0030219 26 0.906
translational initiation GO:0006413 24 0.906
negative regulation of myeloid cell differentiation GO:0045638 38 0.905
enamel mineralization GO:0070166 7 0.904
striated muscle tissue development GO:0014706 293 0.902
alpha beta t cell differentiation GO:0046632 69 0.901
positive regulation of bile acid biosynthetic process GO:0070859 1 0.897
regulation of cardiac muscle tissue development GO:0055024 31 0.895
positive regulation of transcription via serum response element binding GO:0010735 1 0.894
positive regulation of interleukin 13 production GO:0032736 4 0.894
limb morphogenesis GO:0035108 149 0.892
atrial septum development GO:0003283 12 0.892
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.891
cell fate commitment GO:0045165 210 0.891
epithelial cell proliferation GO:0050673 174 0.891
appendage morphogenesis GO:0035107 149 0.891
regulation of peptide hormone secretion GO:0090276 75 0.890
Mouse
nephron morphogenesis GO:0072028 69 0.889
regulation of cellular ketone metabolic process GO:0010565 66 0.887
Worm
neuron migration GO:0001764 122 0.886
Mouse
growth plate cartilage chondrocyte growth GO:0003430 2 0.879
t cell differentiation GO:0030217 174 0.878
circulatory system process GO:0003013 197 0.877
organic hydroxy compound metabolic process GO:1901615 203 0.877
cardiac muscle tissue growth GO:0055017 37 0.876
nephron epithelium morphogenesis GO:0072088 68 0.876
regulation of apoptotic signaling pathway GO:2001233 197 0.874
amine metabolic process GO:0009308 45 0.871
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.871
response to steroid hormone GO:0048545 56 0.869
Rat
embryonic heart tube development GO:0035050 65 0.867
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.864
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.864
forebrain neuron differentiation GO:0021879 52 0.863
multi multicellular organism process GO:0044706 109 0.863
negative regulation of fibroblast proliferation GO:0048147 14 0.861
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.860
metanephric glomerular mesangium development GO:0072223 3 0.858
regulation of mammary gland involution GO:1903519 4 0.857
multicellular organismal signaling GO:0035637 91 0.856
regulation of binding GO:0051098 111 0.855
myeloid cell differentiation GO:0030099 233 0.854
wound healing GO:0042060 157 0.854
lipid homeostasis GO:0055088 63 0.853
Mouse
brown fat cell differentiation GO:0050873 36 0.850
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.849
mammary gland branching involved in pregnancy GO:0060745 6 0.849
placenta blood vessel development GO:0060674 31 0.847
Mouse
cardiac conduction system development GO:0003161 12 0.844
venous blood vessel morphogenesis GO:0048845 7 0.844
septum primum development GO:0003284 4 0.843
regulation of histone h3 k4 methylation GO:0051569 12 0.842
regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000733 1 0.842
type i pneumocyte differentiation GO:0060509 7 0.838
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.837
canonical wnt signaling pathway involved in metanephric kidney development GO:0061290 2 0.837
cellular response to hormone stimulus GO:0032870 150 0.837
Rat
ureteric bud formation GO:0060676 7 0.835
closure of optic fissure GO:0061386 2 0.835
prostate gland development GO:0030850 48 0.834
cellular response to acid chemical GO:0071229 68 0.834
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.834
negative regulation of glial cell proliferation GO:0060253 4 0.833
regulation of forebrain neuron differentiation GO:2000977 2 0.831
mesenchymal cell development GO:0014031 93 0.830
monocarboxylic acid metabolic process GO:0032787 191 0.830
Worm
digestive tract morphogenesis GO:0048546 147 0.828
Mouse
myeloid cell homeostasis GO:0002262 114 0.828
digestive system development GO:0055123 200 0.828
Mouse Rat
stem cell development GO:0048864 219 0.825
regulation of heart growth GO:0060420 31 0.823
growth involved in heart morphogenesis GO:0003241 4 0.821
blood circulation GO:0008015 195 0.820
cellular response to x ray GO:0071481 2 0.820
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.818
axon guidance GO:0007411 141 0.816
sertoli cell differentiation GO:0060008 18 0.814
regulation of hormone secretion GO:0046883 88 0.814
Mouse
cellular ketone metabolic process GO:0042180 84 0.813
Worm
regulation of t cell activation GO:0050863 170 0.812
atrial septum morphogenesis GO:0060413 11 0.812
mesonephric epithelium development GO:0072163 94 0.811
cell type specific apoptotic process GO:0097285 268 0.810
histone methylation GO:0016571 71 0.808
immune effector process GO:0002252 321 0.808
lymphocyte differentiation GO:0030098 242 0.808
sterol homeostasis GO:0055092 45 0.805
Mouse
pallium development GO:0021543 120 0.802
Mouse
ventricular septum development GO:0003281 42 0.801
hair follicle morphogenesis GO:0031069 29 0.799
carbon catabolite activation of transcription GO:0045991 4 0.799
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.798
antimicrobial peptide production GO:0002775 2 0.797
regulation of definitive erythrocyte differentiation GO:0010724 3 0.797
cellular response to lipid GO:0071396 145 0.796
Mouse
ventricular cardiac myofibril assembly GO:0055005 3 0.792
positive regulation of programmed cell death GO:0043068 218 0.792
Rat
regulation of cardiac muscle tissue growth GO:0055021 26 0.791
cardiocyte differentiation GO:0035051 87 0.790
regulation of myeloid leukocyte differentiation GO:0002761 58 0.789
hair cycle phase GO:0044851 16 0.788
positive regulation of striated muscle cell differentiation GO:0051155 35 0.785
transmission of nerve impulse GO:0019226 76 0.785
extrinsic apoptotic signaling pathway GO:0097191 126 0.785
skeletal muscle organ development GO:0060538 163 0.784
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.781
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.777
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.776
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.775
atrioventricular node development GO:0003162 3 0.773
cardiac septum morphogenesis GO:0060411 46 0.771
embryonic heart tube left right pattern formation GO:0060971 5 0.771
heart field specification GO:0003128 6 0.768
kidney epithelium development GO:0072073 121 0.764
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.763
cerebral cortex development GO:0021987 86 0.762
Mouse
embryonic viscerocranium morphogenesis GO:0048703 8 0.761
leukocyte differentiation GO:0002521 342 0.761
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.761
spermatid differentiation GO:0048515 115 0.760
muscle cell differentiation GO:0042692 261 0.757
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.756
regulation of cytokine production GO:0001817 266 0.755
cellular amine metabolic process GO:0044106 44 0.754
regulation of neuron differentiation GO:0045664 281 0.753
sertoli cell fate commitment GO:0060010 1 0.753
cardiac muscle tissue morphogenesis GO:0055008 44 0.751
blood vessel morphogenesis GO:0048514 285 0.749
Mouse
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.748
negative regulation of immature t cell proliferation GO:0033087 3 0.747
neural crest cell development GO:0014032 48 0.744
hair follicle development GO:0001942 85 0.743
cell migration involved in endocardial cushion formation GO:0003273 3 0.743
embryonic organ morphogenesis GO:0048562 276 0.741
peptide transport GO:0015833 133 0.741
Mouse
lateral mesodermal cell differentiation GO:0048371 3 0.740
negative regulation of neural precursor cell proliferation GO:2000178 18 0.739
regulation of cell activation GO:0050865 289 0.738
small molecule biosynthetic process GO:0044283 132 0.738
hormone secretion GO:0046879 128 0.738
Mouse
negative regulation of macrophage differentiation GO:0045650 4 0.737
urogenital system development GO:0001655 261 0.737
carbohydrate metabolic process GO:0005975 230 0.735
response to retinoic acid GO:0032526 56 0.734
Human Mouse Rat
aortic valve morphogenesis GO:0003180 4 0.734
glutamate metabolic process GO:0006536 9 0.733
regulation of secretion GO:0051046 274 0.732
Mouse
growth plate cartilage development GO:0003417 14 0.731
protein catabolic process GO:0030163 221 0.731
cardiac chamber development GO:0003205 108 0.728
hindbrain development GO:0030902 128 0.727
female genitalia morphogenesis GO:0048807 3 0.724
dsdna loop formation GO:0090579 2 0.724
myelination GO:0042552 74 0.723
Rat
sinoatrial node cell differentiation GO:0060921 3 0.722
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.722
regulation of antimicrobial humoral response GO:0002759 3 0.722
atrioventricular valve formation GO:0003190 5 0.721
macromolecule catabolic process GO:0009057 281 0.721
forebrain neuron fate commitment GO:0021877 13 0.721
mesangial cell differentiation GO:0072007 4 0.721
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.721
organic acid biosynthetic process GO:0016053 86 0.716
endodermal cell fate commitment GO:0001711 12 0.715
endocardial cell differentiation GO:0060956 4 0.715
maternal process involved in female pregnancy GO:0060135 32 0.714
regulation of gliogenesis GO:0014013 50 0.712
axon extension involved in axon guidance GO:0048846 14 0.710
cellular divalent inorganic cation homeostasis GO:0072503 127 0.707
regulation of lymphocyte differentiation GO:0045619 107 0.706
positive regulation of apoptotic process GO:0043065 217 0.702
Rat
regulation of bmp signaling pathway GO:0030510 60 0.698
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.698
mitral valve development GO:0003174 4 0.697
regulation of cellular amino acid metabolic process GO:0006521 5 0.696
tissue regeneration GO:0042246 22 0.694
axon ensheathment GO:0008366 76 0.693
Rat
negative regulation of protein metabolic process GO:0051248 282 0.693
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.692
axonogenesis GO:0007409 274 0.691
cell cycle arrest GO:0007050 37 0.691
renal vesicle induction GO:0072034 3 0.690
retinoic acid receptor signaling pathway GO:0048384 17 0.690
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.688
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.686
trachea formation GO:0060440 3 0.684
regulation of cardiac muscle cell proliferation GO:0060043 23 0.683
secondary heart field specification GO:0003139 6 0.680
cell cell signaling involved in kidney development GO:0060995 2 0.680
apoptotic signaling pathway GO:0097190 306 0.680
t cell activation GO:0042110 289 0.680
regulation of transferase activity GO:0051338 263 0.680
regulation of steroid biosynthetic process GO:0050810 26 0.678
activation of immune response GO:0002253 138 0.673
glutamine family amino acid metabolic process GO:0009064 15 0.673
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.671
pyramidal neuron migration GO:0021852 1 0.671
ureteric bud development GO:0001657 94 0.671
ureteric bud morphogenesis GO:0060675 62 0.668
t cell activation involved in immune response GO:0002286 43 0.667
cholesterol storage GO:0010878 4 0.667
development of primary sexual characteristics GO:0045137 143 0.667
negative regulation of cell proliferation involved in mesonephros development GO:2000607 1 0.665
positive regulation of transcription by glucose GO:0046016 3 0.665
erythrocyte differentiation GO:0030218 88 0.662
regulation of t cell differentiation GO:0045580 83 0.661
positive regulation of cellular amine metabolic process GO:0033240 5 0.659
germ cell development GO:0007281 185 0.659
apoptotic process involved in embryonic digit morphogenesis GO:1902263 3 0.659
forebrain generation of neurons GO:0021872 63 0.659
cardiac ventricle morphogenesis GO:0003208 50 0.658
interleukin 4 production GO:0032633 24 0.658
heart induction GO:0003129 2 0.657
epidermis development GO:0008544 187 0.656
epithelial cell fate commitment GO:0072148 13 0.652
atrial cardiac muscle cell differentiation GO:0055011 2 0.651
regulation of lymphocyte activation GO:0051249 240 0.650
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.649
pituitary gland development GO:0021983 38 0.647
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.644
embryonic heart tube morphogenesis GO:0003143 51 0.644
mesenchymal cell differentiation GO:0048762 107 0.642
cardiac atrium morphogenesis GO:0003209 23 0.641
epithelial cell proliferation involved in prostate gland development GO:0060767 11 0.641
endocrine system development GO:0035270 98 0.640
hindbrain formation GO:0021576 1 0.640
prostate gland epithelium morphogenesis GO:0060740 31 0.639
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.637
outflow tract septum morphogenesis GO:0003148 11 0.636
cardiac muscle tissue regeneration GO:0061026 1 0.636
inflammatory response GO:0006954 244 0.636
Rat
cardiac muscle hypertrophy GO:0003300 23 0.635
myelination in peripheral nervous system GO:0022011 19 0.634
steroid metabolic process GO:0008202 119 0.632
atrioventricular valve morphogenesis GO:0003181 13 0.630
regulation of reproductive process GO:2000241 66 0.630
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.629
renal tubule morphogenesis GO:0061333 72 0.628
determination of heart left right asymmetry GO:0061371 48 0.625
signal transduction in absence of ligand GO:0038034 55 0.625
regulation of homeostatic process GO:0032844 182 0.624
Mouse
metanephric glomerular endothelium development GO:0072264 1 0.624
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.623
lung epithelial cell differentiation GO:0060487 29 0.623
hepaticobiliary system development GO:0061008 67 0.623
Rat
antigen receptor mediated signaling pathway GO:0050851 64 0.621
nephron tubule epithelial cell differentiation GO:0072160 11 0.618
cell proliferation in hindbrain GO:0021534 10 0.618
gabaergic neuron differentiation GO:0097154 11 0.617
primitive erythrocyte differentiation GO:0060319 3 0.614
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.613
protein secretion GO:0009306 111 0.611
histone lysine methylation GO:0034968 50 0.609
prostate glandular acinus development GO:0060525 12 0.609
negative regulation of t cell proliferation GO:0042130 38 0.609
glial cell differentiation GO:0010001 131 0.609
thyroid hormone mediated signaling pathway GO:0002154 3 0.607
neuroblast fate determination GO:0007400 1 0.606
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.605
renal system development GO:0072001 225 0.602
positive regulation of transcription regulatory region dna binding GO:2000679 1 0.599
negative regulation of fat cell differentiation GO:0045599 36 0.599
negative regulation of granulocyte differentiation GO:0030853 3 0.593
regulation of leukocyte differentiation GO:1902105 159 0.590
cardiac chamber morphogenesis GO:0003206 93 0.586
negative regulation of glial cell differentiation GO:0045686 21 0.585
lipid transport GO:0006869 98 0.584
spermatogenesis GO:0007283 284 0.584
neuroblast fate commitment GO:0014017 1 0.584
negative regulation of protein modification process GO:0031400 163 0.582
forelimb morphogenesis GO:0035136 40 0.582
peptidyl lysine modification GO:0018205 77 0.582
pulmonary valve development GO:0003177 5 0.581
cellular amino acid metabolic process GO:0006520 103 0.581
s shaped body morphogenesis GO:0072050 6 0.578
regulation of myotube differentiation GO:0010830 62 0.573
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000703 1 0.569
skeletal muscle cell differentiation GO:0035914 66 0.568
negative regulation of cellular protein metabolic process GO:0032269 247 0.566
white fat cell differentiation GO:0050872 15 0.566
macromolecule methylation GO:0043414 120 0.565
inositol lipid mediated signaling GO:0048017 41 0.565
negative regulation of interferon gamma production GO:0032689 18 0.563
regulation of somitogenesis GO:0014807 6 0.563
negative regulation of female receptivity GO:0007621 2 0.562
outflow tract morphogenesis GO:0003151 53 0.560
respiratory system development GO:0060541 190 0.557
signal transduction involved in dna damage checkpoint GO:0072422 3 0.556
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.555
regulation of protein targeting GO:1903533 61 0.554
cytoplasmic sequestering of transcription factor GO:0042994 5 0.553
heart valve development GO:0003170 23 0.553
response to osmotic stress GO:0006970 21 0.552
phospholipid metabolic process GO:0006644 87 0.550
leukocyte activation involved in immune response GO:0002366 126 0.545
regulation of ammonia assimilation cycle GO:2001248 1 0.544
regulation of muscle tissue development GO:1901861 97 0.543
regulation of thyroid hormone mediated signaling pathway GO:0002155 3 0.543
regulation of epithelial cell proliferation involved in prostate gland development GO:0060768 10 0.539
regulation of cardiac chamber morphogenesis GO:1901219 2 0.539
peptide hormone secretion GO:0030072 109 0.539
Mouse
cholesterol homeostasis GO:0042632 44 0.536
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.535
morphogenesis of a branching structure GO:0001763 203 0.535
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.532
regulation of female receptivity GO:0045924 6 0.531
cellular chemical homeostasis GO:0055082 215 0.531
g protein coupled receptor signaling pathway GO:0007186 243 0.530
metanephric s shaped body morphogenesis GO:0072284 2 0.529
lung epithelium development GO:0060428 37 0.529
hematopoietic progenitor cell differentiation GO:0002244 143 0.528
male gamete generation GO:0048232 285 0.528
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.526
bile acid metabolic process GO:0008206 17 0.525
response to acid chemical GO:0001101 111 0.524
Human Mouse Rat
regulation of feeding behavior GO:0060259 3 0.521
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.519
regulation of protein kinase activity GO:0045859 232 0.518
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.517
regulation of fibroblast proliferation GO:0048145 34 0.517
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.517
regulation of striated muscle cell differentiation GO:0051153 81 0.515
protein methylation GO:0006479 81 0.514
renal tubule development GO:0061326 87 0.513
organ maturation GO:0048799 17 0.513
endodermal cell fate determination GO:0007493 2 0.509
cell substrate adhesion GO:0031589 130 0.508
astrocyte activation GO:0048143 2 0.506
histone h3 k27 methylation GO:0070734 11 0.506
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.506
negative regulation of mesodermal cell fate specification GO:0042662 3 0.506
glial cell derived neurotrophic factor receptor signaling pathway GO:0035860 3 0.505
schwann cell differentiation GO:0014037 26 0.505
mesonephric tubule formation GO:0072172 11 0.504
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.503
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.503
regulation of cell cycle process GO:0010564 160 0.503
negative regulation of intracellular transport GO:0032387 38 0.502
female mating behavior GO:0060180 8 0.502
pulmonary valve morphogenesis GO:0003184 5 0.501
sinoatrial node development GO:0003163 4 0.501
hindlimb morphogenesis GO:0035137 42 0.501
lateral mesoderm morphogenesis GO:0048369 3 0.499
mitral valve morphogenesis GO:0003183 4 0.497
heart trabecula formation GO:0060347 14 0.496
mesonephric tubule development GO:0072164 94 0.495
mesonephric tubule morphogenesis GO:0072171 63 0.495
hormone mediated signaling pathway GO:0009755 23 0.493
positive regulation of lipid biosynthetic process GO:0046889 18 0.492
divalent inorganic cation homeostasis GO:0072507 138 0.491
cardiac atrium development GO:0003230 24 0.491
metanephric comma shaped body morphogenesis GO:0072278 1 0.491
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.487
labyrinthine layer blood vessel development GO:0060716 21 0.486
positive regulation of homeostatic process GO:0032846 64 0.485
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.484
carboxylic acid biosynthetic process GO:0046394 86 0.483
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.483
endocytosis GO:0006897 168 0.482
Worm
cation homeostasis GO:0055080 212 0.482
myeloid cell apoptotic process GO:0033028 22 0.481
lipid biosynthetic process GO:0008610 179 0.479
ossification GO:0001503 216 0.479
circadian regulation of gene expression GO:0032922 48 0.478
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.478
cell differentiation involved in embryonic placenta development GO:0060706 26 0.476
Mouse
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.474
eye photoreceptor cell differentiation GO:0001754 41 0.474
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.474
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.473
regulation of secretion by cell GO:1903530 249 0.470
Mouse
positive regulation of interleukin 5 production GO:0032754 5 0.470
bmp signaling pathway GO:0030509 93 0.470
lung development GO:0030324 164 0.470
wnt signaling pathway GO:0016055 188 0.469
regulation of leukocyte apoptotic process GO:2000106 56 0.468
oxidation reduction process GO:0055114 342 0.466
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.466
production of molecular mediator of immune response GO:0002440 103 0.466
epithelial cell differentiation involved in kidney development GO:0035850 23 0.466
intestinal absorption GO:0050892 13 0.466
epithelial cell development GO:0002064 159 0.465
multicellular organism growth GO:0035264 161 0.464

Rxra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.959
cancer DOID:162 0 0.823
organ system cancer DOID:0050686 0 0.526