IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

growth plate cartilage chondrocyte development

GO:0003431

The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "growth plate cartilage chondrocyte development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "growth plate cartilage chondrocyte development" (in gray)

Name	Description	Probability	Func Analog Organism
Tgfbr2	transforming growth factor, beta receptor II	1.000
Rarg	retinoic acid receptor, gamma	1.000
Sox9	SRY-box containing gene 9	0.998
Foxc1	forkhead box C1	0.998
Fgfr2	fibroblast growth factor receptor 2	0.998
Bmp4	bone morphogenetic protein 4	0.994
Tgfb2	transforming growth factor, beta 2	0.993
Rarb	retinoic acid receptor, beta	0.992	Mouse
Ednra	endothelin receptor type A	0.978
Vegfa	vascular endothelial growth factor A	0.959
Rara	retinoic acid receptor, alpha	0.959	Mouse
Tbx1	T-box 1	0.954
Rxra	retinoid X receptor alpha	0.949
Acvr1	activin A receptor, type 1	0.940	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.939
Chrd	chordin	0.930
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.926
Ece1	endothelin converting enzyme 1	0.923
Foxc2	forkhead box C2	0.921
Prrx1	paired related homeobox 1	0.904
Eya1	eyes absent 1 homolog (Drosophila)	0.880
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.880
Smo	smoothened homolog (Drosophila)	0.870
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.848
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.832
Tcfap2a	transcription factor AP-2, alpha	0.830
Shh	sonic hedgehog	0.814
Hoxa3	homeobox A3	0.813
Apc	adenomatosis polyposis coli	0.756
Fgfr3	fibroblast growth factor receptor 3	0.722
Bmp7	bone morphogenetic protein 7	0.700
Pten	phosphatase and tensin homolog	0.697
Gli3	GLI-Kruppel family member GLI3	0.665
Pitx2	paired-like homeodomain transcription factor 2	0.627
Tgfbr1	transforming growth factor, beta receptor I	0.626	Mouse
Fgf8	fibroblast growth factor 8	0.616
Jag1	jagged 1	0.577
Nos3	nitric oxide synthase 3, endothelial cell	0.484
Pax3	paired box gene 3	0.439
Gli2	GLI-Kruppel family member GLI2	0.421
Hand2	heart and neural crest derivatives expressed transcript 2	0.404
Dlx5	distal-less homeobox 5	0.387
Hoxa1	homeobox A1	0.374
Pax2	paired box gene 2	0.373
Prrx2	paired related homeobox 2	0.359
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.344	Mouse
Bmp2	bone morphogenetic protein 2	0.309
Ctnnb1	catenin (cadherin associated protein), beta 1	0.254
Bmper	BMP-binding endothelial regulator	0.245
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.238
Meox2	mesenchyme homeobox 2	0.226
Fbn1	fibrillin 1	0.201
Isl1	ISL1 transcription factor, LIM/homeodomain	0.191
Pbx1	pre B-cell leukemia transcription factor 1	0.180
Eng	endoglin	0.175
Runx2	runt related transcription factor 2	0.171
Sox4	SRY-box containing gene 4	0.171
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.153
Rbl2	retinoblastoma-like 2	0.140
Hoxa2	homeobox A2	0.135
Mesp1	mesoderm posterior 1	0.133
Esr1	estrogen receptor 1 (alpha)	0.114
Gja1	gap junction protein, alpha 1	0.112
Tgfbr3	transforming growth factor, beta receptor III	0.109
Ghr	growth hormone receptor	0.109
Nf1	neurofibromatosis 1	0.106
Pax8	paired box gene 8	0.099
Hoxb3	homeobox B3	0.095
Fgfrl1	fibroblast growth factor receptor-like 1	0.094
Mkl2	MKL/myocardin-like 2	0.094
Emx2	empty spiracles homolog 2 (Drosophila)	0.086
Smad4	MAD homolog 4 (Drosophila)	0.083
Msx1	homeobox, msh-like 1	0.082
Ptch1	patched homolog 1	0.072
Gata4	GATA binding protein 4	0.064
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.062
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.062
Csf1	colony stimulating factor 1 (macrophage)	0.061
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.057
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.057
Zeb1	zinc finger E-box binding homeobox 1	0.056
Smad3	MAD homolog 3 (Drosophila)	0.055
Bmp5	bone morphogenetic protein 5	0.055
Twist2	twist homolog 2 (Drosophila)	0.052
Ar	androgen receptor	0.051
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.051
Duox2	dual oxidase 2	0.050
Ret	ret proto-oncogene	0.049
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.048
Vangl2	vang-like 2 (van gogh, Drosophila)	0.048
Idua	iduronidase, alpha-L-	0.047
Shc1	src homology 2 domain-containing transforming protein C1	0.047
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.046
Egfr	epidermal growth factor receptor	0.046
Kif3a	kinesin family member 3A	0.044
Wnt4	wingless-related MMTV integration site 4	0.044
Cdh5	cadherin 5	0.041
Hoxa5	homeobox A5	0.040
Foxg1	forkhead box G1	0.040
Rdh10	retinol dehydrogenase 10 (all-trans)	0.040
Prkg1	protein kinase, cGMP-dependent, type I	0.038
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.038
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.037
Xiap	X-linked inhibitor of apoptosis	0.037
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.036
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.036
Apoe	apolipoprotein E	0.036
Lox	lysyl oxidase	0.035
Smad6	MAD homolog 6 (Drosophila)	0.034
Zfpm2	zinc finger protein, multitype 2	0.033
Alx1	ALX homeobox 1	0.033
Trp53	transformation related protein 53	0.032
Otx2	orthodenticle homolog 2 (Drosophila)	0.030
Fgf10	fibroblast growth factor 10	0.029
Lhx1	LIM homeobox protein 1	0.028
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.028
Col1a1	collagen, type I, alpha 1	0.028
Gsc	goosecoid homeobox	0.028
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.027	Mouse
Ext1	exostoses (multiple) 1	0.025
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.025
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.024
Chd7	chromodomain helicase DNA binding protein 7	0.023
Fgf9	fibroblast growth factor 9	0.022
Dbp	D site albumin promoter binding protein	0.021
Fzd4	frizzled homolog 4 (Drosophila)	0.021
Igf1	insulin-like growth factor 1	0.021
Tef	thyrotroph embryonic factor	0.020
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.020
Ntf3	neurotrophin 3	0.020
Prdm16	PR domain containing 16	0.020
Gpc3	glypican 3	0.019
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.019
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.019
Hipk3	homeodomain interacting protein kinase 3	0.019
Pkd1	polycystic kidney disease 1 homolog	0.019
Itga8	integrin alpha 8	0.018
Foxi3	forkhead box I3	0.018
Plxnd1	plexin D1	0.018
Pthlh	parathyroid hormone-like peptide	0.018
Mapk8	mitogen-activated protein kinase 8	0.018
Fst	follistatin	0.017
Ednrb	endothelin receptor type B	0.017
Smad5	MAD homolog 5 (Drosophila)	0.017
Adam17	a disintegrin and metallopeptidase domain 17	0.017
Vcl	vinculin	0.016
Lrp6	low density lipoprotein receptor-related protein 6	0.016
Nr1d1	nuclear receptor subfamily 1, group D, member 1	0.016	Mouse
Ids	iduronate 2-sulfatase	0.016
Dlg1	discs, large homolog 1 (Drosophila)	0.016
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.015
Fuz	fuzzy homolog (Drosophila)	0.015
Agtr1a	angiotensin II receptor, type 1a	0.015
Npr2	natriuretic peptide receptor 2	0.014
Nfic	nuclear factor I/C	0.014
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.014
Tshz1	teashirt zinc finger family member 1	0.014
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.014
Msx2	homeobox, msh-like 2	0.014
Cav1	caveolin 1, caveolae protein	0.014
Bcl2	B-cell leukemia/lymphoma 2	0.014
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.013
Zbtb7a	zinc finger and BTB domain containing 7a	0.013
Inha	inhibin alpha	0.013
Ncoa1	nuclear receptor coactivator 1	0.013
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.013
Mef2c	myocyte enhancer factor 2C	0.013
Irs2	insulin receptor substrate 2	0.013
Sod3	superoxide dismutase 3, extracellular	0.013
Tbx15	T-box 15	0.013
Wnt5a	wingless-related MMTV integration site 5A	0.013
Ppfia2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.013
Nrp1	neuropilin 1	0.013
Efnb2	ephrin B2	0.012
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.012
Kiss1	KiSS-1 metastasis-suppressor	0.012
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.012
Fzd1	frizzled homolog 1 (Drosophila)	0.012
Agtr2	angiotensin II receptor, type 2	0.012
Fmn1	formin 1	0.012
Gata3	GATA binding protein 3	0.012
Slc12a2	solute carrier family 12, member 2	0.012
Tbx3	T-box 3	0.011
Tgfb1	transforming growth factor, beta 1	0.011
Vstm2a	V-set and transmembrane domain containing 2A	0.011
Sdc3	syndecan 3	0.011
Psen1	presenilin 1	0.011
Dclk3	doublecortin-like kinase 3	0.011
Gm715	predicted pseudogene 715	0.011
Dlx2	distal-less homeobox 2	0.011
Ptprb	protein tyrosine phosphatase, receptor type, B	0.011
Notch2	Notch gene homolog 2 (Drosophila)	0.011
Otx1	orthodenticle homolog 1 (Drosophila)	0.011
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.010
Gna11	guanine nucleotide binding protein, alpha 11	0.010
Smad1	MAD homolog 1 (Drosophila)	0.010
Acvrl1	activin A receptor, type II-like 1	0.010	Mouse
Cpd	carboxypeptidase D	0.010
Zfp503	zinc finger protein 503	0.010
Prlr	prolactin receptor	0.010
Itgav	integrin alpha V	0.010
Hand1	heart and neural crest derivatives expressed transcript 1	0.010