Mus musculus

118 known processes

Setdb1

SET domain, bifurcated 1

(Aliases: KMT1E,mKIAA0067,ESET,AU022152,MGC90670)

Setdb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.602
protein modification by small protein conjugation GO:0032446 187 0.593
protein modification by small protein conjugation or removal GO:0070647 207 0.577
histone modification GO:0016570 159 0.570
modification dependent macromolecule catabolic process GO:0043632 133 0.544
cellular macromolecule catabolic process GO:0044265 206 0.474
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.442
chromatin modification GO:0016568 187 0.380
neural tube development GO:0021915 160 0.359
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.348
cellular protein catabolic process GO:0044257 155 0.342
chromatin organization GO:0006325 206 0.306
positive regulation of immature t cell proliferation GO:0033091 4 0.304
modification dependent protein catabolic process GO:0019941 133 0.292
regulation of transcription from rna polymerase ii promoter by galactose GO:0000431 1 0.288
covalent chromatin modification GO:0016569 163 0.282
apoptotic signaling pathway GO:0097190 306 0.265
regulation of mitotic cell cycle phase transition GO:1901990 73 0.239
compound eye development GO:0048749 1 0.238
spinal cord development GO:0021510 81 0.232
embryonic organ morphogenesis GO:0048562 276 0.230
regulation of response to drug GO:2001023 2 0.224
spinal cord motor neuron differentiation GO:0021522 35 0.223
embryonic epithelial tube formation GO:0001838 130 0.217
myeloid cell differentiation GO:0030099 233 0.216
regulation of apoptotic signaling pathway GO:2001233 197 0.202
macromolecule methylation GO:0043414 120 0.197
smoothened signaling pathway GO:0007224 105 0.182
negative regulation of cell cycle process GO:0010948 69 0.175
Worm
hematopoietic progenitor cell differentiation GO:0002244 143 0.171
cellular response to dna damage stimulus GO:0006974 207 0.171
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.166
single organism nuclear import GO:1902593 95 0.166
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.165
negative regulation of myeloid cell differentiation GO:0045638 38 0.158
internal protein amino acid acetylation GO:0006475 42 0.152
positive regulation of protein modification process GO:0031401 299 0.149
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.148
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.147
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.147
histone lysine methylation GO:0034968 50 0.143
determination of left right symmetry GO:0007368 80 0.139
regulation of protein catabolic process GO:0042176 108 0.133
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.129
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.128
camera type eye development GO:0043010 266 0.125
spinal cord dorsal ventral patterning GO:0021513 23 0.124
positive regulation of apoptotic process GO:0043065 217 0.123
regulation of proteolysis GO:0030162 164 0.120
dna methylation GO:0006306 43 0.117
Fly
neural tube formation GO:0001841 108 0.117
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.115
epithelial tube formation GO:0072175 130 0.114
dna alkylation GO:0006305 43 0.114
Fly
regulation of cellular protein catabolic process GO:1903362 61 0.113
protein catabolic process GO:0030163 221 0.112
tube closure GO:0060606 91 0.112
regulation of myeloid cell differentiation GO:0045637 96 0.111
epithelial tube morphogenesis GO:0060562 303 0.110
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.108
intrinsic apoptotic signaling pathway GO:0097193 132 0.108
histone methylation GO:0016571 71 0.108
negative regulation of immune system process GO:0002683 209 0.107
dorsal ventral neural tube patterning GO:0021904 28 0.107
regulation of transcription by galactose GO:0000409 1 0.107
development of primary sexual characteristics GO:0045137 143 0.103
Worm
immune effector process GO:0002252 321 0.100
protein methylation GO:0006479 81 0.100
skeletal system development GO:0001501 356 0.098
cytoplasmic transport GO:0016482 234 0.097
ventral spinal cord development GO:0021517 48 0.097
blood circulation GO:0008015 195 0.096
central nervous system neuron differentiation GO:0021953 162 0.095
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.091
gene silencing GO:0016458 38 0.090
Fly
positive regulation of lymphocyte activation GO:0051251 140 0.089
macromolecule catabolic process GO:0009057 281 0.087
histone acetylation GO:0016573 41 0.086
skin development GO:0043588 220 0.085
negative regulation of cellular protein metabolic process GO:0032269 247 0.084
protein ubiquitination GO:0016567 171 0.083
pharynx development GO:0060465 1 0.082
nuclear transport GO:0051169 139 0.082
circulatory system process GO:0003013 197 0.080
morphogenesis of embryonic epithelium GO:0016331 159 0.079
positive regulation of growth GO:0045927 104 0.078
appendage development GO:0048736 166 0.076
positive regulation of programmed cell death GO:0043068 218 0.075
negative regulation of mitotic cell cycle GO:0045930 58 0.074
regulation of cellular response to drug GO:2001038 1 0.073
spinal cord motor neuron cell fate specification GO:0021520 13 0.073
histone h2a ubiquitination GO:0033522 3 0.071
peptidyl lysine modification GO:0018205 77 0.069
lymphocyte differentiation GO:0030098 242 0.069
regulation of protein targeting GO:1903533 61 0.069
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.068
negative regulation of embryonic development GO:0045992 22 0.068
multicellular organism growth GO:0035264 161 0.066
regulation of protein processing GO:0070613 96 0.066
ventral spinal cord interneuron differentiation GO:0021514 16 0.065
megakaryocyte development GO:0035855 15 0.064
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.064
positive regulation of transcription from rna polymerase ii promoter by galactose GO:0000435 1 0.064
regulation of cellular catabolic process GO:0031329 242 0.064
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.063
proteasomal protein catabolic process GO:0010498 98 0.063
dna packaging GO:0006323 30 0.063
leukocyte differentiation GO:0002521 342 0.060
regulation of embryonic development GO:0045995 71 0.059
positive regulation of keratinocyte differentiation GO:0045618 3 0.059
nuclear division GO:0000280 158 0.058
Worm Fly
regulation of innate immune response GO:0045088 91 0.058
cell fate commitment GO:0045165 210 0.057
Worm
protein acylation GO:0043543 64 0.057
protein localization to nucleus GO:0034504 121 0.057
regulation of cytoplasmic transport GO:1903649 112 0.056
neural tube closure GO:0001843 90 0.056
regulation of smoothened signaling pathway GO:0008589 58 0.055
cell differentiation in spinal cord GO:0021515 53 0.055
protein localization to organelle GO:0033365 185 0.054
gonad development GO:0008406 141 0.053
Worm
dna repair GO:0006281 107 0.053
regulation of protein sumoylation GO:0033233 4 0.052
primary neural tube formation GO:0014020 95 0.052
megakaryocyte differentiation GO:0030219 26 0.051
negative regulation of molecular function GO:0044092 258 0.050
protein sumoylation GO:0016925 14 0.049
regulation of binding GO:0051098 111 0.049
digestive tract development GO:0048565 190 0.049
transcription from rna polymerase i promoter GO:0006360 13 0.049
positive regulation of b cell activation GO:0050871 49 0.048
innate immune response GO:0045087 157 0.047
regulation of protein localization GO:0032880 231 0.047
blood vessel morphogenesis GO:0048514 285 0.047
regulation of protein transport GO:0051223 163 0.046
positive regulation of defense response GO:0031349 124 0.046
regulation of protein binding GO:0043393 60 0.046
dna conformation change GO:0071103 37 0.045
lymphocyte proliferation GO:0046651 164 0.044
epidermis development GO:0008544 187 0.044
dna metabolic process GO:0006259 303 0.044
Fly
regulation of protein import into nucleus GO:0042306 52 0.044
b cell activation involved in immune response GO:0002312 50 0.044
cell fate specification GO:0001708 72 0.044
ventral spinal cord interneuron fate commitment GO:0060579 14 0.043
dna integrity checkpoint GO:0031570 28 0.043
genitalia development GO:0048806 37 0.042
Worm
mitotic cell cycle GO:0000278 195 0.042
regulation of lymphocyte activation GO:0051249 240 0.041
negative regulation of intracellular transport GO:0032387 38 0.041
canonical wnt signaling pathway GO:0060070 130 0.041
regulation of megakaryocyte differentiation GO:0045652 7 0.041
regulation of cell cycle phase transition GO:1901987 77 0.041
positive regulation of proteolysis GO:0045862 85 0.040
regulation of leukocyte differentiation GO:1902105 159 0.039
regulation of ossification GO:0030278 112 0.039
positive regulation of cell death GO:0010942 224 0.039
regulation of transcription factor import into nucleus GO:0042990 24 0.039
regulation of wnt signaling pathway GO:0030111 123 0.039
negative regulation of cell cycle phase transition GO:1901988 48 0.038
regulation of proteasomal protein catabolic process GO:0061136 46 0.038
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.038
spermatogenesis GO:0007283 284 0.038
regulation of t cell differentiation in thymus GO:0033081 24 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
placenta development GO:0001890 140 0.037
regulation of protein ubiquitination GO:0031396 52 0.037
histone monoubiquitination GO:0010390 3 0.037
regulation of cell activation GO:0050865 289 0.037
t cell proliferation GO:0042098 120 0.036
fertilization GO:0009566 127 0.036
regulation of t cell proliferation GO:0042129 92 0.036
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.036
limb development GO:0060173 166 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.034
organelle fission GO:0048285 170 0.034
Worm Fly
cell type specific apoptotic process GO:0097285 268 0.034
positive regulation of cell activation GO:0050867 158 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
positive regulation of transcription by galactose GO:0000411 1 0.034
negative regulation of cellular catabolic process GO:0031330 47 0.033
sensory organ morphogenesis GO:0090596 242 0.033
positive regulation of innate immune response GO:0045089 80 0.033
negative regulation of intracellular protein transport GO:0090317 27 0.033
ventral spinal cord interneuron specification GO:0021521 11 0.033
embryonic heart tube morphogenesis GO:0003143 51 0.033
dna recombination GO:0006310 92 0.032
protein import into nucleus GO:0006606 95 0.032
regulation of organelle organization GO:0033043 289 0.032
Worm
response to acid chemical GO:0001101 111 0.032
morphogenesis of a branching epithelium GO:0061138 193 0.032
keratinocyte differentiation GO:0030216 48 0.031
positive regulation of apoptotic signaling pathway GO:2001235 95 0.031
regulation of osteoblast differentiation GO:0045667 67 0.031
regulation of histone h3 k36 methylation GO:0000414 1 0.030
mitotic g2 dna damage checkpoint GO:0007095 8 0.030
positive regulation of receptor activity GO:2000273 17 0.030
regulation of histone methylation GO:0031060 30 0.030
spinal cord patterning GO:0021511 25 0.029
oocyte axis specification GO:0007309 2 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
neuron fate specification GO:0048665 30 0.029
intracellular mrna localization GO:0008298 4 0.029
nuclear import GO:0051170 95 0.029
regulation of glucose metabolic process GO:0010906 60 0.028
neural precursor cell proliferation GO:0061351 121 0.028
heterocycle catabolic process GO:0046700 280 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
developmental maturation GO:0021700 193 0.028
cellular response to lipid GO:0071396 145 0.028
mitotic cell cycle checkpoint GO:0007093 31 0.028
histone h4 k16 acetylation GO:0043984 3 0.028
double strand break repair GO:0006302 48 0.028
protein kinase b signaling GO:0043491 74 0.027
lymphocyte activation involved in immune response GO:0002285 93 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
determination of heart left right asymmetry GO:0061371 48 0.027
regulation of cell cycle GO:0051726 281 0.027
Worm
oocyte construction GO:0007308 2 0.027
regulation of chromatin silencing GO:0031935 2 0.027
regulation of t cell activation GO:0050863 170 0.026
internal peptidyl lysine acetylation GO:0018393 42 0.026
peptidyl amino acid modification GO:0018193 336 0.026
positive regulation of protein sumoylation GO:0033235 3 0.026
mitotic cell cycle process GO:1903047 159 0.026
single organism cell adhesion GO:0098602 156 0.026
cellular response to nutrient levels GO:0031669 64 0.025
negative regulation of nervous system development GO:0051961 156 0.025
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 14 0.025
cerebral cortex development GO:0021987 86 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
regulation of t cell differentiation GO:0045580 83 0.024
forebrain development GO:0030900 302 0.024
endodermal cell fate specification GO:0001714 4 0.023
protein import GO:0017038 101 0.023
regulation of multi organism process GO:0043900 111 0.023
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.023
negative regulation of binding GO:0051100 39 0.023
negative regulation of cytoplasmic transport GO:1903650 29 0.023
heart morphogenesis GO:0003007 178 0.023
negative regulation of protein catabolic process GO:0042177 36 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
rna interference GO:0016246 2 0.022
gland development GO:0048732 330 0.022
negative regulation of protein processing GO:0010955 79 0.022
regulation of intracellular transport GO:0032386 159 0.022
negative regulation of protein maturation GO:1903318 79 0.022
stem cell division GO:0017145 30 0.022
Fly
regulation of canonical wnt signaling pathway GO:0060828 82 0.021
negative regulation of hematopoietic progenitor cell differentiation GO:1901533 4 0.021
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.021
cellular amine metabolic process GO:0044106 44 0.021
connective tissue development GO:0061448 179 0.021
chromosome organization involved in meiosis GO:0070192 39 0.021
transcription from rna polymerase iii promoter GO:0006383 3 0.021
protein maturation GO:0051604 176 0.021
regulation of lymphocyte proliferation GO:0050670 117 0.021
cell aging GO:0007569 35 0.021
histone h4 acetylation GO:0043967 10 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.021
response to oxidative stress GO:0006979 123 0.021
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.021
regulation of protein maturation GO:1903317 96 0.021
response to inorganic substance GO:0010035 96 0.021
histone ubiquitination GO:0016574 10 0.020
histone h2a monoubiquitination GO:0035518 1 0.020
somitogenesis GO:0001756 69 0.020
rho protein signal transduction GO:0007266 32 0.020
embryonic skeletal system morphogenesis GO:0048704 91 0.020
rna processing GO:0006396 105 0.020
wnt signaling pathway GO:0016055 188 0.020
cell division GO:0051301 120 0.019
Worm Fly
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
maintenance of location GO:0051235 89 0.019
vagus nerve development GO:0021564 3 0.019
hindbrain development GO:0030902 128 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
trunk segmentation GO:0035290 4 0.019
ion transmembrane transport GO:0034220 361 0.019
b cell proliferation GO:0042100 53 0.019
embryonic placenta development GO:0001892 98 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
cell fate specification involved in pattern specification GO:0060573 11 0.019
regulation of nucleocytoplasmic transport GO:0046822 73 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
chromatin silencing at rdna GO:0000183 3 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
negative regulation of proteolysis GO:0045861 74 0.018
transmembrane transport GO:0055085 412 0.018
tube formation GO:0035148 140 0.018
defense response to other organism GO:0098542 197 0.018
regulation of receptor activity GO:0010469 41 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
protein alkylation GO:0008213 81 0.018
regulation of cell cycle process GO:0010564 160 0.018
Worm
negative regulation of protein transport GO:0051224 46 0.018
t cell differentiation in thymus GO:0033077 77 0.018
muscle tissue development GO:0060537 308 0.018
positive regulation of cell development GO:0010720 237 0.018
cell fate commitment involved in pattern specification GO:0060581 14 0.018
skeletal system morphogenesis GO:0048705 203 0.018
regulation of transmembrane transport GO:0034762 128 0.017
mrna processing GO:0006397 63 0.017
dna damage checkpoint GO:0000077 26 0.017
methylation GO:0032259 134 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
organ growth GO:0035265 117 0.017
his purkinje system development GO:0003164 4 0.017
germ cell development GO:0007281 185 0.017
Fly
rac protein signal transduction GO:0016601 13 0.017
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.017
response to fibroblast growth factor GO:0071774 47 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
mapk cascade GO:0000165 281 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
cellular ketone metabolic process GO:0042180 84 0.017
regulation of neuron differentiation GO:0045664 281 0.017
intracellular receptor signaling pathway GO:0030522 74 0.017
meiotic cell cycle GO:0051321 122 0.017
Worm Fly
chromosome condensation GO:0030261 10 0.017
appendage morphogenesis GO:0035107 149 0.017
synapsis GO:0007129 34 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
response to organic cyclic compound GO:0014070 198 0.016
skeletal muscle organ development GO:0060538 163 0.016
negative regulation of protein ubiquitination GO:0031397 19 0.016
regulation of protein complex assembly GO:0043254 83 0.016
dna modification GO:0006304 50 0.016
Fly
leukocyte proliferation GO:0070661 172 0.016
gene silencing by rna GO:0031047 19 0.016
t cell differentiation GO:0030217 174 0.016
regulation of transcription during meiosis GO:0051037 1 0.016
Fly
single fertilization GO:0007338 82 0.016
defense response to bacterium GO:0042742 119 0.016
regulation of protein stability GO:0031647 52 0.016
positive regulation of t cell differentiation in thymus GO:0033089 13 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
mesoderm development GO:0007498 100 0.016
t cell activation involved in immune response GO:0002286 43 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
Worm
nitrogen compound transport GO:0071705 271 0.016
cellular response to oxidative stress GO:0034599 76 0.016
negative regulation of protein import into nucleus GO:0042308 21 0.015
carbohydrate metabolic process GO:0005975 230 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
carbon catabolite regulation of transcription GO:0045990 4 0.015
cellular protein complex assembly GO:0043623 116 0.015
regulation of protein localization to nucleus GO:1900180 60 0.015
response to ionizing radiation GO:0010212 42 0.015
action potential GO:0001508 78 0.015
negative regulation of dna replication GO:0008156 4 0.015
neural tube patterning GO:0021532 43 0.015
histone h3 k4 methylation GO:0051568 23 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
positive regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902231 6 0.015
monosaccharide metabolic process GO:0005996 106 0.015
negative regulation of protein localization to nucleus GO:1900181 23 0.015
mrna metabolic process GO:0016071 84 0.015
meiosis i GO:0007127 60 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.014
posttranscriptional gene silencing by rna GO:0035194 10 0.014
bone development GO:0060348 120 0.014
negative regulation of growth GO:0045926 99 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.014
negative regulation of organelle organization GO:0010639 90 0.014
Worm
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
rostrocaudal neural tube patterning GO:0021903 12 0.014
positive regulation of dna templated transcription elongation GO:0032786 2 0.014
regulation of histone h3 k4 methylation GO:0051569 12 0.014
retina development in camera type eye GO:0060041 119 0.014
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.014
regulation of hormone levels GO:0010817 211 0.014
mitotic nuclear division GO:0007067 48 0.014
neuron apoptotic process GO:0051402 142 0.014
dephosphorylation GO:0016311 129 0.014
ribonucleotide metabolic process GO:0009259 291 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
positive regulation of nervous system development GO:0051962 221 0.013
biomineral tissue development GO:0031214 64 0.013
labyrinthine layer development GO:0060711 49 0.013
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 1 0.013
b cell activation GO:0042113 161 0.013
lens development in camera type eye GO:0002088 62 0.013
telomere capping GO:0016233 4 0.013
regulation of response to dna damage stimulus GO:2001020 34 0.013
ossification GO:0001503 216 0.013
regulation of chromosome organization GO:0033044 83 0.013
regulation of stem cell proliferation GO:0072091 78 0.013
cell cycle checkpoint GO:0000075 47 0.013
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.013
negative regulation of protein binding GO:0032091 17 0.013
visceral motor neuron differentiation GO:0021524 3 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
nucleotide excision repair GO:0006289 13 0.013
cellular response to sterol GO:0036315 2 0.013
chemotaxis GO:0006935 247 0.013
digestive system development GO:0055123 200 0.013
somatic diversification of immune receptors GO:0002200 53 0.013
renal system development GO:0072001 225 0.013
intracellular protein transport GO:0006886 204 0.012
cytokine production GO:0001816 319 0.012
response to reactive oxygen species GO:0000302 56 0.012
negative regulation of smoothened signaling pathway GO:0045879 25 0.012
regulation of transcription by chromatin organization GO:0034401 0 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
positive regulation of leukocyte differentiation GO:1902107 86 0.012
regulation of membrane potential GO:0042391 192 0.012
response to extracellular stimulus GO:0009991 127 0.012
mammary placode formation GO:0060596 4 0.012
embryonic skeletal system development GO:0048706 120 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
response to retinoic acid GO:0032526 56 0.012
positive regulation of immature t cell proliferation in thymus GO:0033092 3 0.012
eosinophil migration GO:0072677 3 0.012
cajal body organization GO:0030576 1 0.012
synaptonemal complex assembly GO:0007130 13 0.012
cation transmembrane transport GO:0098655 266 0.012
protein processing GO:0016485 163 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
mitochondrion organization GO:0007005 134 0.012
response to growth factor GO:0070848 198 0.012
striated muscle tissue development GO:0014706 293 0.012
aromatic compound catabolic process GO:0019439 286 0.012
heterochromatin organization GO:0070828 4 0.011
negative regulation of cell development GO:0010721 169 0.011
humoral immune response GO:0006959 57 0.011
localization within membrane GO:0051668 4 0.011
cell cell recognition GO:0009988 44 0.011
posttranscriptional gene silencing GO:0016441 10 0.011
protein targeting GO:0006605 143 0.011
hexose metabolic process GO:0019318 98 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
positive regulation of t cell proliferation GO:0042102 52 0.011
membrane organization GO:0061024 245 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
transcription factor import into nucleus GO:0042991 26 0.011
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
dendrite development GO:0016358 115 0.011
cell adhesion GO:0007155 329 0.011
sa node cell action potential GO:0086015 4 0.011
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.011
dna replication GO:0006260 52 0.011
protein autophosphorylation GO:0046777 61 0.011
glucose metabolic process GO:0006006 92 0.011
female gamete generation GO:0007292 74 0.011
Fly
organonitrogen compound catabolic process GO:1901565 264 0.011
blastocyst development GO:0001824 80 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
stem cell development GO:0048864 219 0.011
lateral inhibition GO:0046331 1 0.011
neuronal action potential GO:0019228 54 0.011
bundle of his development GO:0003166 4 0.011
response to sterol GO:0036314 4 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of neuron projection development GO:0010975 169 0.010
positive regulation of cell cycle GO:0045787 92 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
muscle cell development GO:0055001 133 0.010
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.010
regulation of keratinocyte apoptotic process GO:1902172 1 0.010
muscle tissue morphogenesis GO:0060415 53 0.010
limb morphogenesis GO:0035108 149 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
regulation of cardiac chamber morphogenesis GO:1901219 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
positive regulation of immune effector process GO:0002699 107 0.010
regulation of homeostatic process GO:0032844 182 0.010
mitochondrial genome maintenance GO:0000002 15 0.010
regulation of mrna metabolic process GO:1903311 43 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.010
regulation of muscle tissue development GO:1901861 97 0.010
respiratory tube development GO:0030323 167 0.010
negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:1901621 6 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
homeostasis of number of cells GO:0048872 210 0.010

Setdb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.278
organ system cancer DOID:0050686 0 0.259
cancer DOID:162 0 0.259
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
hematopoietic system disease DOID:74 0 0.017
immune system disease DOID:2914 0 0.017
central nervous system disease DOID:331 0 0.017
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
neurodegenerative disease DOID:1289 0 0.013
nervous system cancer DOID:3093 0 0.013
central nervous system cancer DOID:3620 0 0.013