IMP

Process View

Mus musculus

1 genes annotated in mouse

canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation" (in gray)

Name	Description	Probability	Func Analog Organism
Pitx2	paired-like homeodomain transcription factor 2	0.979
Tbx3	T-box 3	0.979	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.941
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.806
Tbx5	T-box 5	0.799	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.767
Scn5a	sodium channel, voltage-gated, type V, alpha	0.759
Tcfap2a	transcription factor AP-2, alpha	0.607
Chd7	chromodomain helicase DNA binding protein 7	0.592
Hoxa1	homeobox A1	0.579
Sall4	sal-like 4 (Drosophila)	0.385
Shh	sonic hedgehog	0.349
Foxg1	forkhead box G1	0.343
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.333
Tbx4	T-box 4	0.317	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.315
Gja5	gap junction protein, alpha 5	0.295
Pax2	paired box gene 2	0.283
Lrp5	low density lipoprotein receptor-related protein 5	0.232
Hand2	heart and neural crest derivatives expressed transcript 2	0.197
Lrp6	low density lipoprotein receptor-related protein 6	0.178
Otx2	orthodenticle homolog 2 (Drosophila)	0.178
Smad6	MAD homolog 6 (Drosophila)	0.178
Fgf10	fibroblast growth factor 10	0.168
Ighmbp2	immunoglobulin mu binding protein 2	0.164
Vangl2	vang-like 2 (van gogh, Drosophila)	0.160
Eya1	eyes absent 1 homolog (Drosophila)	0.148
Foxc2	forkhead box C2	0.142
Lef1	lymphoid enhancer binding factor 1	0.117
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.104
Lmx1a	LIM homeobox transcription factor 1 alpha	0.095
Hand1	heart and neural crest derivatives expressed transcript 1	0.093
Pax3	paired box gene 3	0.089
Foxc1	forkhead box C1	0.089
Bdnf	brain derived neurotrophic factor	0.089
Fgf8	fibroblast growth factor 8	0.089
Gsc	goosecoid homeobox	0.086
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.072
Gbx2	gastrulation brain homeobox 2	0.071
Zic3	zinc finger protein of the cerebellum 3	0.070
Irx3	Iroquois related homeobox 3 (Drosophila)	0.070
Jag1	jagged 1	0.068
Gata4	GATA binding protein 4	0.058
Noto	notochord homolog (Xenopus laevis)	0.057
Dll4	delta-like 4 (Drosophila)	0.057
Wnt3a	wingless-related MMTV integration site 3A	0.056
Prrx1	paired related homeobox 1	0.055
Wt1	Wilms tumor 1 homolog	0.054
Gsk3b	glycogen synthase kinase 3 beta	0.046
Hoxa3	homeobox A3	0.046
Msx1	homeobox, msh-like 1	0.045
Myf5	myogenic factor 5	0.041
T	brachyury	0.040	Mouse
Efnb2	ephrin B2	0.039
Alx1	ALX homeobox 1	0.038
Hoxa13	homeobox A13	0.035
Nodal	nodal	0.034
Zeb1	zinc finger E-box binding homeobox 1	0.034
Bmp5	bone morphogenetic protein 5	0.033
Tcf21	transcription factor 21	0.032
Hoxa2	homeobox A2	0.032
Htt	huntingtin	0.031
Rnf2	ring finger protein 2	0.031
Rnf111	ring finger 111	0.030
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.030
Bmp4	bone morphogenetic protein 4	0.030
Wdr5	WD repeat domain 5	0.030
Gata3	GATA binding protein 3	0.030
Gata6	GATA binding protein 6	0.029
Rarb	retinoic acid receptor, beta	0.028
Tbx1	T-box 1	0.028	Mouse
Rarg	retinoic acid receptor, gamma	0.028
Smad7	MAD homolog 7 (Drosophila)	0.026
Otx1	orthodenticle homolog 1 (Drosophila)	0.026
Cxadr	coxsackie virus and adenovirus receptor	0.025
Prdm6	PR domain containing 6	0.024
Foxh1	forkhead box H1	0.024
Rxra	retinoid X receptor alpha	0.024
Mecom	MDS1 and EVI1 complex locus	0.024
Runx2	runt related transcription factor 2	0.024
Dlx2	distal-less homeobox 2	0.024
Hmx3	H6 homeobox 3	0.024
Pax9	paired box gene 9	0.023
Tbx20	T-box 20	0.023	Mouse
Hoxd1	homeobox D1	0.022
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.022
Sox2	SRY-box containing gene 2	0.022
Col13a1	collagen, type XIII, alpha 1	0.020
Sox9	SRY-box containing gene 9	0.020
Axin2	axin2	0.020
Osr1	odd-skipped related 1 (Drosophila)	0.020
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.020
Hoxb3	homeobox B3	0.019
Gata5	GATA binding protein 5	0.019
Wnt5a	wingless-related MMTV integration site 5A	0.019
Hoxd3	homeobox D3	0.019
Chrd	chordin	0.019
Lhx9	LIM homeobox protein 9	0.019
Lpar3	lysophosphatidic acid receptor 3	0.019
Ryr2	ryanodine receptor 2, cardiac	0.019
Ntf3	neurotrophin 3	0.018
Pcdh12	protocadherin 12	0.018
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.018
Mn1	meningioma 1	0.018
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.018
Xirp1	xin actin-binding repeat containing 1	0.018
Lhx1	LIM homeobox protein 1	0.017
Isl1	ISL1 transcription factor, LIM/homeodomain	0.017
Emx2	empty spiracles homolog 2 (Drosophila)	0.016
Pou4f2	POU domain, class 4, transcription factor 2	0.016
Vstm2b	V-set and transmembrane domain containing 2B	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.015
Zfp503	zinc finger protein 503	0.015
Hoxb2	homeobox B2	0.015
Klf14	Kruppel-like factor 14	0.014
Gata2	GATA binding protein 2	0.014
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.014
Nkx3-2	NK3 homeobox 2	0.014
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.014
Dmtf1	cyclin D binding myb-like transcription factor 1	0.014
Foxf1a	forkhead box F1a	0.014
Sox11	SRY-box containing gene 11	0.014
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.013
Setdb1	SET domain, bifurcated 1	0.013
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Dlx5	distal-less homeobox 5	0.013
Ripply3	ripply3 homolog (zebrafish)	0.013
Dnahc5	dynein, axonemal, heavy chain 5	0.013
Ltbp1	latent transforming growth factor beta binding protein 1	0.013
Tnni2	troponin I, skeletal, fast 2	0.013
Msc	musculin	0.013
Myf6	myogenic factor 6	0.013
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.013
Msx2	homeobox, msh-like 2	0.012
Myl3	myosin, light polypeptide 3	0.012
Pou5f1	POU domain, class 5, transcription factor 1	0.012
Zfp598	zinc finger protein 598	0.012
Hoxa10	homeobox A10	0.012
Vegfa	vascular endothelial growth factor A	0.012
Myl7	myosin, light polypeptide 7, regulatory	0.012
Snai1	snail homolog 1 (Drosophila)	0.012
Fgfr3	fibroblast growth factor receptor 3	0.012
Asb12	ankyrin repeat and SOCS box-containing 12	0.012
Hoxb4	homeobox B4	0.012
Asb10	ankyrin repeat and SOCS box-containing 10	0.012
Cdx2	caudal type homeobox 2	0.012
Bcl6	B-cell leukemia/lymphoma 6	0.012
Trp63	transformation related protein 63	0.011
Atoh8	atonal homolog 8 (Drosophila)	0.011
Nckap5l	NCK-associated protein 5-like	0.011
Runx3	runt related transcription factor 3	0.011
Invs	inversin	0.011
Hoxa4	homeobox A4	0.011
Gli3	GLI-Kruppel family member GLI3	0.011
Acvr2b	activin receptor IIB	0.011
Gzmk	granzyme K	0.011
Hoxa11	homeobox A11	0.011
Pax7	paired box gene 7	0.011
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.011
Hoxd11	homeobox D11	0.010
Myoz3	myozenin 3	0.010
Olig3	oligodendrocyte transcription factor 3	0.010
Shox2	short stature homeobox 2	0.010
Rest	RE1-silencing transcription factor	0.010
Hoxb1	homeobox B1	0.010
Sp8	trans-acting transcription factor 8	0.010
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.010
Apc	adenomatosis polyposis coli	0.010
Hes7	hairy and enhancer of split 7 (Drosophila)	0.010