Mus musculus

59 known processes

Shank2

SH3/ankyrin domain gene 2

(Aliases: KIAA1022,mKIAA1022)

Shank2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.950
synaptic transmission GO:0007268 329 0.855
regulation of neuronal synaptic plasticity GO:0048168 30 0.760
Mouse
conditioned taste aversion GO:0001661 4 0.747
associative learning GO:0008306 61 0.717
Mouse
regulation of synaptic plasticity GO:0048167 87 0.675
transmembrane transport GO:0055085 412 0.558
Mouse
learning GO:0007612 98 0.503
ion transmembrane transport GO:0034220 361 0.451
Mouse
response to ammonium ion GO:0060359 21 0.444
regulation of neurotransmitter levels GO:0001505 87 0.430
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.418
Mouse
regulation of membrane potential GO:0042391 192 0.386
Mouse
cellular response to ethanol GO:0071361 3 0.381
inorganic ion transmembrane transport GO:0098660 234 0.324
response to cocaine GO:0042220 14 0.317
calcium ion transport GO:0006816 159 0.311
negative regulation of phosphate metabolic process GO:0045936 184 0.311
cation transmembrane transport GO:0098655 266 0.303
olfactory learning GO:0008355 2 0.300
protein localization to membrane GO:0072657 108 0.293
Mouse
negative regulation of phosphorylation GO:0042326 166 0.290
cognition GO:0050890 149 0.283
neurotransmitter transport GO:0006836 76 0.282
membrane organization GO:0061024 245 0.276
Mouse
learning or memory GO:0007611 148 0.275
sensory perception GO:0007600 245 0.263
activation of meiosis GO:0090427 4 0.263
regulation of secretion by cell GO:1903530 249 0.259
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 3 0.259
neurotransmitter secretion GO:0007269 62 0.258
adherens junction organization GO:0034332 28 0.256
regulation of protein kinase activity GO:0045859 232 0.253
cation transport GO:0006812 399 0.251
response to alkaloid GO:0043279 34 0.250
mapk cascade GO:0000165 281 0.244
Mouse
oocyte anterior posterior axis specification GO:0007314 2 0.236
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.235
memory GO:0007613 58 0.235
protein catabolic process GO:0030163 221 0.232
regulation of ion transmembrane transporter activity GO:0032412 54 0.232
Mouse
regulation of secretion GO:0051046 274 0.230
glutamate receptor signaling pathway GO:0007215 35 0.226
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.213
regulation of cellular amine metabolic process GO:0033238 20 0.200
regulation of mapk cascade GO:0043408 248 0.198
negative regulation of intracellular signal transduction GO:1902532 167 0.193
activation of meiosis involved in egg activation GO:0060466 2 0.191
response to organonitrogen compound GO:0010243 246 0.185
divalent inorganic cation transport GO:0072511 178 0.184
establishment of organelle localization GO:0051656 122 0.180
dendritic spine organization GO:0097061 26 0.178
Mouse
multicellular organismal response to stress GO:0033555 62 0.176
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.165
divalent metal ion transport GO:0070838 172 0.163
regulation of short term neuronal synaptic plasticity GO:0048172 8 0.156
regulation of cellular amino acid metabolic process GO:0006521 5 0.156
visual learning GO:0008542 44 0.154
protein kinase a signaling GO:0010737 7 0.153
positive regulation of mapk cascade GO:0043410 170 0.152
regulation of map kinase activity GO:0043405 120 0.150
regulation of cellular protein catabolic process GO:1903362 61 0.150
regulation of transporter activity GO:0032409 57 0.149
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.148
macromolecule catabolic process GO:0009057 281 0.144
cellular amino acid metabolic process GO:0006520 103 0.143
ras protein signal transduction GO:0007265 77 0.142
nitrogen compound transport GO:0071705 271 0.142
peptidyl serine phosphorylation GO:0018105 74 0.140
synapse organization GO:0050808 125 0.137
establishment or maintenance of cell polarity GO:0007163 86 0.136
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.136
regulation of ion transport GO:0043269 215 0.136
Mouse
establishment of vesicle localization GO:0051650 81 0.135
regulation of cellular ketone metabolic process GO:0010565 66 0.134
positive regulation of meiotic cell cycle GO:0051446 15 0.133
positive regulation of membrane potential GO:0045838 15 0.132
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.131
behavioral response to cocaine GO:0048148 10 0.129
neuron neuron synaptic transmission GO:0007270 69 0.129
Mouse
regulation of synaptic vesicle exocytosis GO:2000300 11 0.127
organic acid transport GO:0015849 101 0.126
regulation of protein serine threonine kinase activity GO:0071900 157 0.125
response to organic cyclic compound GO:0014070 198 0.124
vesicle localization GO:0051648 86 0.123
negative regulation of cell proliferation GO:0008285 296 0.121
regulation of glutamate receptor signaling pathway GO:1900449 16 0.120
Mouse
camera type eye development GO:0043010 266 0.118
regulation of synaptic transmission glutamatergic GO:0051966 19 0.116
Mouse
visual behavior GO:0007632 45 0.115
vesicle organization GO:0016050 60 0.114
long term synaptic potentiation GO:0060291 25 0.114
cellular amine metabolic process GO:0044106 44 0.114
adult behavior GO:0030534 135 0.112
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.112
Mouse
negative regulation of molecular function GO:0044092 258 0.111
hormone secretion GO:0046879 128 0.109
endocytosis GO:0006897 168 0.109
g protein coupled receptor signaling pathway GO:0007186 243 0.108
synaptic vesicle localization GO:0097479 59 0.106
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.104
protein localization to cell junction GO:1902414 3 0.103
smooth muscle contraction GO:0006939 44 0.102
response to catecholamine GO:0071869 4 0.102
cellular nitrogen compound catabolic process GO:0044270 280 0.100
social behavior GO:0035176 21 0.098
locomotory behavior GO:0007626 195 0.098
Mouse
organelle localization GO:0051640 179 0.097
protein localization to synapse GO:0035418 11 0.096
Mouse
oocyte construction GO:0007308 2 0.094
b 1 b cell differentiation GO:0001923 3 0.094
small gtpase mediated signal transduction GO:0007264 97 0.094
nucleoside phosphate metabolic process GO:0006753 338 0.093
regulation of organelle organization GO:0033043 289 0.092
Mouse
endomembrane system organization GO:0010256 147 0.088
amine metabolic process GO:0009308 45 0.088
actin polymerization or depolymerization GO:0008154 54 0.087
sensory perception of pain GO:0019233 47 0.087
multicellular organismal signaling GO:0035637 91 0.087
protein autophosphorylation GO:0046777 61 0.086
axonogenesis GO:0007409 274 0.086
negative regulation of protein metabolic process GO:0051248 282 0.085
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.083
regulation of cellular response to stress GO:0080135 159 0.083
sodium ion transport GO:0006814 73 0.082
synaptic transmission gabaergic GO:0051932 19 0.082
purine ribonucleotide metabolic process GO:0009150 290 0.080
exocytosis GO:0006887 121 0.080
pole plasm assembly GO:0007315 2 0.080
regulation of exocytosis GO:0017157 61 0.079
regulation of cellular catabolic process GO:0031329 242 0.079
heterocycle catabolic process GO:0046700 280 0.079
cell junction maintenance GO:0034331 4 0.078
transmission of nerve impulse GO:0019226 76 0.077
immune response activating signal transduction GO:0002757 116 0.077
negative regulation of cellular protein metabolic process GO:0032269 247 0.077
synaptic vesicle fusion to presynaptic membrane GO:0031629 3 0.077
purine ribonucleotide catabolic process GO:0009154 208 0.075
fear response GO:0042596 33 0.075
Mouse
immune response regulating signaling pathway GO:0002764 125 0.075
oocyte axis specification GO:0007309 2 0.074
cellular macromolecule catabolic process GO:0044265 206 0.074
positive regulation of nervous system development GO:0051962 221 0.073
Mouse
locomotory exploration behavior GO:0035641 10 0.072
Mouse
synaptic vesicle transport GO:0048489 57 0.072
leukocyte proliferation GO:0070661 172 0.071
aromatic compound catabolic process GO:0019439 286 0.071
regulation of synapse assembly GO:0051963 29 0.070
cell cell junction organization GO:0045216 72 0.070
response to inorganic substance GO:0010035 96 0.070
stress activated protein kinase signaling cascade GO:0031098 81 0.069
protein localization to adherens junction GO:0071896 2 0.069
insulin secretion GO:0030073 89 0.069
regulation of homeostatic process GO:0032844 182 0.069
peptidyl amino acid modification GO:0018193 336 0.069
second messenger mediated signaling GO:0019932 73 0.069
negative regulation of phosphorus metabolic process GO:0010563 184 0.068
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.068
dephosphorylation GO:0016311 129 0.068
positive regulation of protein kinase activity GO:0045860 144 0.067
activation of mapk activity GO:0000187 59 0.067
b 1a b cell differentiation GO:0002337 2 0.067
sequestering of calcium ion GO:0051208 18 0.066
gtp catabolic process GO:0006184 143 0.066
ribose phosphate metabolic process GO:0019693 291 0.065
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.065
glycosyl compound catabolic process GO:1901658 206 0.065
circadian rhythm GO:0007623 114 0.064
single organism cell adhesion GO:0098602 156 0.064
peptidyl serine autophosphorylation GO:0036289 1 0.064
positive regulation of secretion by cell GO:1903532 114 0.064
regulation of ion transmembrane transport GO:0034765 119 0.063
Mouse
cellular lipid metabolic process GO:0044255 323 0.063
response to lipopolysaccharide GO:0032496 128 0.063
response to radiation GO:0009314 165 0.062
negative regulation of cellular amine metabolic process GO:0033239 1 0.062
negative regulation of mapk cascade GO:0043409 65 0.061
neuromuscular process controlling balance GO:0050885 59 0.061
Mouse
positive regulation of ion transport GO:0043270 65 0.060
Mouse
regulation of transferase activity GO:0051338 263 0.060
synaptic vesicle recycling GO:0036465 19 0.060
peptidyl serine modification GO:0018209 83 0.060
regulation of grooming behavior GO:2000821 4 0.060
Mouse
synaptic growth at neuromuscular junction GO:0051124 6 0.060
muscle contraction GO:0006936 101 0.060
negative regulation of protein catabolic process GO:0042177 36 0.060
negative regulation of protein phosphorylation GO:0001933 126 0.060
regulation of hydrolase activity GO:0051336 246 0.059
cellular ketone metabolic process GO:0042180 84 0.059
regulation of system process GO:0044057 200 0.059
dendritic spine development GO:0060996 30 0.059
Mouse
response to light stimulus GO:0009416 135 0.059
glucose transport GO:0015758 56 0.059
negative regulation of protein modification process GO:0031400 163 0.059
response to calcium ion GO:0051592 20 0.058
autophagy GO:0006914 45 0.058
exploration behavior GO:0035640 21 0.058
germ cell development GO:0007281 185 0.057
purine nucleoside triphosphate catabolic process GO:0009146 203 0.057
nucleotide catabolic process GO:0009166 217 0.057
potassium ion transport GO:0006813 52 0.057
positive regulation of organelle organization GO:0010638 128 0.057
purine nucleotide metabolic process GO:0006163 302 0.057
regulation of cd24 biosynthetic process GO:2000559 1 0.057
inclusion body assembly GO:0070841 3 0.056
gtp metabolic process GO:0046039 144 0.056
positive regulation of axon extension GO:0045773 20 0.056
regulation of apoptotic signaling pathway GO:2001233 197 0.055
camp metabolic process GO:0046058 40 0.055
oocyte differentiation GO:0009994 35 0.055
protein oligomerization GO:0051259 67 0.055
nucleoside triphosphate metabolic process GO:0009141 230 0.055
maintenance of location GO:0051235 89 0.054
regulation of erk1 and erk2 cascade GO:0070372 71 0.054
positive regulation of protein modification process GO:0031401 299 0.054
rhythmic process GO:0048511 174 0.053
Worm
nucleoside phosphate catabolic process GO:1901292 222 0.053
membrane depolarization GO:0051899 64 0.053
Mouse
fertilization GO:0009566 127 0.053
adherens junction assembly GO:0034333 22 0.053
regulation of transmembrane transport GO:0034762 128 0.052
Mouse
oocyte development GO:0048599 33 0.052
circulatory system process GO:0003013 197 0.052
actin filament polymerization GO:0030041 44 0.052
mitotic cell cycle process GO:1903047 159 0.052
cell fate commitment GO:0045165 210 0.051
apoptotic signaling pathway GO:0097190 306 0.051
organic hydroxy compound metabolic process GO:1901615 203 0.051
ribonucleotide metabolic process GO:0009259 291 0.051
regulation of kinase activity GO:0043549 249 0.051
digestive system development GO:0055123 200 0.051
response to extracellular stimulus GO:0009991 127 0.050
Rat
response to morphine GO:0043278 9 0.050
regulation of nuclear division GO:0051783 56 0.050
intraspecies interaction between organisms GO:0051703 21 0.050
organophosphate catabolic process GO:0046434 232 0.049
regulation of receptor activity GO:0010469 41 0.049
Mouse
muscle system process GO:0003012 141 0.049
regulation of cell cycle process GO:0010564 160 0.049
organelle fusion GO:0048284 28 0.049
positive regulation of excitatory postsynaptic membrane potential GO:2000463 14 0.048
Mouse
jnk cascade GO:0007254 72 0.048
cytoplasmic transport GO:0016482 234 0.048
sensory perception of touch GO:0050975 2 0.048
activation of immune response GO:0002253 138 0.048
peptide transport GO:0015833 133 0.048
regulation of actin filament length GO:0030832 45 0.048
maternal determination of anterior posterior axis embryo GO:0008358 2 0.047
cellular response to abiotic stimulus GO:0071214 56 0.047
primary amino compound metabolic process GO:1901160 8 0.047
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.046
regulation of cell motility GO:2000145 236 0.046
regulation of protein catabolic process GO:0042176 108 0.046
regulation of vesicle mediated transport GO:0060627 139 0.046
carbohydrate derivative catabolic process GO:1901136 231 0.046
short term memory GO:0007614 5 0.046
regulation of cell cycle GO:0051726 281 0.046
intrinsic apoptotic signaling pathway GO:0097193 132 0.046
regulation of sensory perception of pain GO:0051930 8 0.046
peptide hormone secretion GO:0030072 109 0.045
carbohydrate homeostasis GO:0033500 128 0.045
mitotic cell cycle GO:0000278 195 0.045
developmental maturation GO:0021700 193 0.045
purine ribonucleoside catabolic process GO:0046130 205 0.045
cell junction organization GO:0034330 77 0.045
cell junction assembly GO:0034329 52 0.045
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
positive regulation of secretion GO:0051047 130 0.044
lateral inhibition GO:0046331 1 0.044
nuclear division GO:0000280 158 0.044
activation of mapkk activity GO:0000186 15 0.043
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.043
engulfment of apoptotic cell GO:0043652 3 0.043
positive regulation of map kinase activity GO:0043406 84 0.042
response to pain GO:0048265 26 0.042
regulation of peptidyl serine phosphorylation GO:0033135 39 0.042
establishment of synaptic vesicle localization GO:0097480 57 0.042
antigen receptor mediated signaling pathway GO:0050851 64 0.042
meiotic cell cycle GO:0051321 122 0.041
negative regulation of hormone biosynthetic process GO:0032353 4 0.041
cellular response to lipid GO:0071396 145 0.041
adaptive immune response GO:0002250 155 0.041
regulation of sensory perception GO:0051931 8 0.041
peptide secretion GO:0002790 114 0.041
organonitrogen compound catabolic process GO:1901565 264 0.041
purine containing compound metabolic process GO:0072521 311 0.040
microtubule based process GO:0007017 236 0.040
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.040
calcium ion transmembrane transport GO:0070588 85 0.040
amide transport GO:0042886 138 0.040
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.040
purine ribonucleoside metabolic process GO:0046128 241 0.039
single fertilization GO:0007338 82 0.038
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.038
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
behavioral fear response GO:0001662 28 0.038
Mouse
organic anion transport GO:0015711 137 0.038
plasma membrane organization GO:0007009 90 0.037
monosaccharide transport GO:0015749 58 0.037
thermosensory behavior GO:0040040 1 0.037
regulation of cytokine production GO:0001817 266 0.037
cellular response to cytokine stimulus GO:0071345 189 0.037
cell substrate adhesion GO:0031589 130 0.037
skeletal muscle organ development GO:0060538 163 0.037
dendrite development GO:0016358 115 0.037
Mouse
retina development in camera type eye GO:0060041 119 0.037
cellular ion homeostasis GO:0006873 165 0.037
regulation of neuron projection development GO:0010975 169 0.037
Mouse
microtubule based movement GO:0007018 84 0.037
nucleotide metabolic process GO:0009117 332 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.036
Mouse
b cell activation GO:0042113 161 0.036
regulation of metal ion transport GO:0010959 106 0.036
mating GO:0007618 27 0.036
regulation of hormone secretion GO:0046883 88 0.036
b cell receptor signaling pathway GO:0050853 20 0.036
muscle tissue development GO:0060537 308 0.036
positive regulation of cell death GO:0010942 224 0.035
response to metal ion GO:0010038 47 0.035
regulation of actin polymerization or depolymerization GO:0008064 45 0.035
negative regulation of homeostatic process GO:0032845 71 0.035
glucose homeostasis GO:0042593 128 0.035
organelle assembly GO:0070925 177 0.035
protein maturation GO:0051604 176 0.034
lymphocyte mediated immunity GO:0002449 139 0.034
basal protein localization GO:0045175 1 0.034
regulation of fertilization GO:0080154 4 0.034
erk1 and erk2 cascade GO:0070371 77 0.034
response to acid chemical GO:0001101 111 0.034
regulation of ras protein signal transduction GO:0046578 114 0.034
regionalization GO:0003002 337 0.034
action potential GO:0001508 78 0.034
protein localization to plasma membrane GO:0072659 57 0.034
positive regulation of amino acid transport GO:0051957 4 0.034
regulation of intracellular transport GO:0032386 159 0.034
purine nucleotide catabolic process GO:0006195 211 0.033
regulation of calcium ion transport GO:0051924 69 0.033
mitochondrion organization GO:0007005 134 0.033
positive regulation of leukocyte differentiation GO:1902107 86 0.033
negative regulation of monocyte extravasation GO:2000438 1 0.033
regulation of neurotransmitter transport GO:0051588 35 0.033
establishment of protein localization to membrane GO:0090150 54 0.032
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
response to oxidative stress GO:0006979 123 0.032
positive regulation of vesicle fusion GO:0031340 2 0.032
synapse assembly GO:0007416 56 0.032
cyclic nucleotide metabolic process GO:0009187 59 0.031
response to heat GO:0009408 27 0.031
response to starvation GO:0042594 65 0.031
cellular protein catabolic process GO:0044257 155 0.031
adult locomotory behavior GO:0008344 91 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
carboxylic acid transport GO:0046942 100 0.031
regulation of ral gtpase activity GO:0032315 4 0.030
sequestering of metal ion GO:0051238 19 0.030
b cell differentiation GO:0030183 78 0.030
regulation of cell projection organization GO:0031344 206 0.030
Mouse
g1 s transition of mitotic cell cycle GO:0000082 57 0.030
regulation of multi organism process GO:0043900 111 0.030
protein targeting GO:0006605 143 0.030
intracellular protein transport GO:0006886 204 0.030
regulation of t cell activation GO:0050863 170 0.030
regulation of proteolysis GO:0030162 164 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
regulation of actin filament polymerization GO:0030833 38 0.030
negative regulation of immune system process GO:0002683 209 0.030
vesicle fusion GO:0006906 16 0.029
single organismal cell cell adhesion GO:0016337 131 0.029
regulation of leukocyte proliferation GO:0070663 121 0.029
regulation of cell division GO:0051302 76 0.029
regulation of ovulation GO:0060278 3 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
positive regulation of cell projection organization GO:0031346 95 0.029
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.029
locomotor rhythm GO:0045475 8 0.029
stress activated mapk cascade GO:0051403 80 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
cytokine production GO:0001816 319 0.029
cilium assembly GO:0042384 81 0.028
regulation of actin cytoskeleton organization GO:0032956 84 0.028
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
positive regulation of exocytosis GO:0045921 20 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
leukocyte migration GO:0050900 124 0.028
neuron death GO:0070997 154 0.028
response to alcohol GO:0097305 48 0.028
regulation of t cell proliferation GO:0042129 92 0.028
response to molecule of bacterial origin GO:0002237 143 0.028
myeloid leukocyte migration GO:0097529 57 0.027
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.027
positive regulation of neuron differentiation GO:0045666 141 0.027
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.027
feeding behavior GO:0007631 62 0.027
neuronal action potential GO:0019228 54 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
morphogenesis of a polarized epithelium GO:0001738 37 0.027
response to electrical stimulus GO:0051602 8 0.027
cell growth GO:0016049 130 0.027
protein localization to organelle GO:0033365 185 0.027
positive regulation of ras gtpase activity GO:0032320 65 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
response to reactive oxygen species GO:0000302 56 0.026
oogenesis GO:0048477 56 0.026
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.026
Mouse
cellular response to catecholamine stimulus GO:0071870 3 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.026
positive regulation of kinase activity GO:0033674 155 0.026
male gamete generation GO:0048232 285 0.026
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.026
mitotic cytokinesis GO:0000281 4 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
immune effector process GO:0002252 321 0.025
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.025
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.025
synaptic transmission cholinergic GO:0007271 7 0.025
leukocyte differentiation GO:0002521 342 0.025
sensory perception of sound GO:0007605 97 0.025
behavioral defense response GO:0002209 28 0.025
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
sensory perception of light stimulus GO:0050953 54 0.025
calcium ion dependent exocytosis GO:0017156 35 0.025
regulation of glutamate secretion GO:0014048 3 0.025
neuromuscular process GO:0050905 99 0.025
Mouse
ral protein signal transduction GO:0032484 2 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.024
regulation of synaptic transmission gabaergic GO:0032228 17 0.024
positive regulation of nucleotide catabolic process GO:0030813 88 0.024
response to amphetamine GO:0001975 16 0.024
cd24 biosynthetic process GO:0035724 1 0.024
amino acid transport GO:0006865 61 0.024
negative regulation of transferase activity GO:0051348 85 0.024
adherens junction maintenance GO:0034334 1 0.024
muscle cell development GO:0055001 133 0.024
cellular homeostasis GO:0019725 240 0.024
Mouse
epithelial cell proliferation GO:0050673 174 0.024
response to ethanol GO:0045471 18 0.023
actin filament organization GO:0007015 113 0.023
Mouse
regulation of innate immune response GO:0045088 91 0.023
cell division GO:0051301 120 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
regulation of jnk cascade GO:0046328 62 0.023
cell cycle g1 s phase transition GO:0044843 57 0.023
cellular response to electrical stimulus GO:0071257 6 0.023
positive regulation of innate immune response GO:0045089 80 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
negative regulation of lymphocyte proliferation GO:0050672 45 0.023
negative regulation of synapse assembly GO:0051964 3 0.023
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.023
nucleoside metabolic process GO:0009116 246 0.023
cell adhesion GO:0007155 329 0.023
anatomical structure homeostasis GO:0060249 145 0.023
positive regulation of apoptotic signaling pathway GO:2001235 95 0.023
nucleoside catabolic process GO:0009164 206 0.023
cellular potassium ion transport GO:0071804 43 0.023
negative regulation of cell projection organization GO:0031345 56 0.023
actin filament based movement GO:0030048 23 0.022
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.022
regulation of feeding behavior GO:0060259 3 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
glial cell differentiation GO:0010001 131 0.022
regulation of store operated calcium channel activity GO:1901339 1 0.022
sodium ion transmembrane transport GO:0035725 49 0.022
mitotic nuclear division GO:0007067 48 0.022
myotube differentiation GO:0014902 105 0.022
circadian behavior GO:0048512 13 0.022
gland development GO:0048732 330 0.022
positive regulation of cd24 biosynthetic process GO:2000560 1 0.022
anion transport GO:0006820 177 0.022
guanosine containing compound metabolic process GO:1901068 144 0.022
heart contraction GO:0060047 93 0.022
cell type specific apoptotic process GO:0097285 268 0.022
synaptic vesicle maturation GO:0016188 7 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
metal ion homeostasis GO:0055065 189 0.021
homeostasis of number of cells GO:0048872 210 0.021
heart process GO:0003015 94 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
regulation of protein kinase b signaling GO:0051896 56 0.021
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.021
blood circulation GO:0008015 195 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
positive regulation of cell motility GO:2000147 116 0.021
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.021
synaptic transmission glutamatergic GO:0035249 36 0.021
Mouse
operant conditioning GO:0035106 2 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
response to isoquinoline alkaloid GO:0014072 9 0.021
lymphocyte proliferation GO:0046651 164 0.021

Shank2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.022