IMP

Process View

Mus musculus

8 genes annotated in mouse

regulation of sensory perception of pain

GO:0051930

Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of sensory perception of pain"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of sensory perception of pain" (in gray)

Name	Description	Probability	Func Analog Organism
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	1.000
Drd2	dopamine receptor D2	0.708
Dlg4	discs, large homolog 4 (Drosophila)	0.569
Ryr2	ryanodine receptor 2, cardiac	0.414
Ccl2	chemokine (C-C motif) ligand 2	0.228
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.216
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.214	Mouse
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.197
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.182
Dlg2	discs, large homolog 2 (Drosophila)	0.150
Hbb-b1	hemoglobin, beta adult major chain	0.124
Prrx1	paired related homeobox 1	0.121
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.120
Syt2	synaptotagmin II	0.113
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.082
Kl	klotho	0.067
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.064
Myd88	myeloid differentiation primary response gene 88	0.050
Mb	myoglobin	0.049
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.049
Ccr2	chemokine (C-C motif) receptor 2	0.048
Cacna2d2	calcium channel, voltage-dependent, alpha 2/delta subunit 2	0.047
Shank2	SH3/ankyrin domain gene 2	0.046
Mmp9	matrix metallopeptidase 9	0.045
Grm1	glutamate receptor, metabotropic 1	0.045
Bsn	bassoon	0.039
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.038
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.037
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.035
Cd44	CD44 antigen	0.033
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.032
Cnr1	cannabinoid receptor 1 (brain)	0.031
Arc	activity regulated cytoskeletal-associated protein	0.031
Cit	citron	0.030
Prkcc	protein kinase C, gamma	0.029
Nos2	nitric oxide synthase 2, inducible	0.029
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.028
Pparg	peroxisome proliferator activated receptor gamma	0.026
Gad2	glutamic acid decarboxylase 2	0.025
Emx1	empty spiracles homolog 1 (Drosophila)	0.023
Ccr1	chemokine (C-C motif) receptor 1	0.023
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.023
Tlr2	toll-like receptor 2	0.022
Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	0.022
Oprm1	opioid receptor, mu 1	0.022	Rat
Epas1	endothelial PAS domain protein 1	0.021
Lepr	leptin receptor	0.021
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.021
Klk6	kallikrein related-peptidase 6	0.021
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.020
Nos1	nitric oxide synthase 1, neuronal	0.020	Rat
Adrb1	adrenergic receptor, beta 1	0.020
Ptprt	protein tyrosine phosphatase, receptor type, T	0.020
Lin7b	lin-7 homolog B (C. elegans)	0.020
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.019
Il6	interleukin 6	0.019
Homer1	homer homolog 1 (Drosophila)	0.018
Grid2	glutamate receptor, ionotropic, delta 2	0.017
Nrg3	neuregulin 3	0.017
Ptgs2	prostaglandin-endoperoxide synthase 2	0.017
Fbxo41	F-box protein 41	0.017
Hrh1	histamine receptor H1	0.017
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.017
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.017
Plat	plasminogen activator, tissue	0.016
Drd1a	dopamine receptor D1A	0.015
Cux2	cut-like homeobox 2	0.015
Dsg1a	desmoglein 1 alpha	0.015
Plcg1	phospholipase C, gamma 1	0.015
Npy2r	neuropeptide Y receptor Y2	0.015
Sstr1	somatostatin receptor 1	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Oprd1	opioid receptor, delta 1	0.014	Rat
Ret	ret proto-oncogene	0.014
Vip	vasoactive intestinal polypeptide	0.013	Rat
Stx1b	syntaxin 1B	0.013
Sez6	seizure related gene 6	0.013
Gjd3	gap junction protein, delta 3	0.012
Gpr123	G protein-coupled receptor 123	0.012
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.012
Ccr5	chemokine (C-C motif) receptor 5	0.012
Crhr1	corticotropin releasing hormone receptor 1	0.012
ND6	NADH dehydrogenase subunit 6	0.011
Cd14	CD14 antigen	0.011
Neurod6	neurogenic differentiation 6	0.011
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.011
Il12b	interleukin 12b	0.011
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.011
Inadl	InaD-like (Drosophila)	0.011
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	0.011
Csmd1	CUB and Sushi multiple domains 1	0.011
Cxcl2	chemokine (C-X-C motif) ligand 2	0.011
Grpr	gastrin releasing peptide receptor	0.011
Car10	carbonic anhydrase 10	0.010
C3ar1	complement component 3a receptor 1	0.010