Mus musculus

76 known processes

Tgtp2

T-cell specific GTPase 2

(Aliases: OTTMUSG00000005537)

Tgtp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to interferon beta GO:0035458 21 1.000
Mouse
response to protozoan GO:0001562 28 0.976
Mouse
defense response to protozoan GO:0042832 25 0.959
Mouse
defense response to other organism GO:0098542 197 0.841
Mouse
response to interferon beta GO:0035456 22 0.724
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.673
cellular response to interferon gamma GO:0071346 25 0.664
response to interferon gamma GO:0034341 34 0.658
Mouse
regulation of interferon alpha production GO:0032647 5 0.616
cellular response to cytokine stimulus GO:0071345 189 0.615
Mouse
regulation of defense response GO:0031347 233 0.597
nucleotide metabolic process GO:0009117 332 0.594
carbohydrate derivative catabolic process GO:1901136 231 0.590
guanosine containing compound metabolic process GO:1901068 144 0.587
gtp metabolic process GO:0046039 144 0.558
adhesion of symbiont to host GO:0044406 8 0.558
gtp catabolic process GO:0006184 143 0.500
defense response to bacterium GO:0042742 119 0.492
Mouse
organophosphate catabolic process GO:0046434 232 0.485
defense response to gram negative bacterium GO:0050829 28 0.483
purine ribonucleoside catabolic process GO:0046130 205 0.482
cellular nitrogen compound catabolic process GO:0044270 280 0.469
negative regulation of interferon alpha production GO:0032687 1 0.461
innate immune response GO:0045087 157 0.451
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.448
regulation of defense response to virus by host GO:0050691 8 0.447
ribonucleoside metabolic process GO:0009119 245 0.446
nucleoside phosphate metabolic process GO:0006753 338 0.440
purine containing compound catabolic process GO:0072523 213 0.438
glycosyl compound metabolic process GO:1901657 246 0.438
nucleotide catabolic process GO:0009166 217 0.432
autophagy GO:0006914 45 0.432
guanosine containing compound catabolic process GO:1901069 144 0.419
ribonucleotide catabolic process GO:0009261 208 0.417
nucleobase containing small molecule metabolic process GO:0055086 352 0.411
negative regulation of defense response to virus by host GO:0050689 1 0.394
purine containing compound metabolic process GO:0072521 311 0.392
purine nucleotide catabolic process GO:0006195 211 0.389
regulation of autophagy GO:0010506 30 0.386
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.383
purine ribonucleotide metabolic process GO:0009150 290 0.375
defense response to virus GO:0051607 68 0.369
purine ribonucleoside metabolic process GO:0046128 241 0.368
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.364
ribonucleoside triphosphate catabolic process GO:0009203 199 0.352
ribose phosphate metabolic process GO:0019693 291 0.348
activation of innate immune response GO:0002218 56 0.340
purine nucleoside triphosphate metabolic process GO:0009144 226 0.337
positive regulation of immune effector process GO:0002699 107 0.336
purine ribonucleotide catabolic process GO:0009154 208 0.329
ribonucleotide metabolic process GO:0009259 291 0.323
ribonucleoside catabolic process GO:0042454 206 0.319
cellular response to interferon alpha GO:0035457 4 0.319
aromatic compound catabolic process GO:0019439 286 0.305
purine nucleoside triphosphate catabolic process GO:0009146 203 0.295
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.286
glycosyl compound catabolic process GO:1901658 206 0.275
regulation of response to biotic stimulus GO:0002831 38 0.262
cellular response to type i interferon GO:0071357 10 0.250
ribonucleoside triphosphate metabolic process GO:0009199 220 0.246
nucleoside phosphate catabolic process GO:1901292 222 0.232
negative regulation of cellular protein metabolic process GO:0032269 247 0.232
regulation of cellular catabolic process GO:0031329 242 0.232
alpha beta t cell activation involved in immune response GO:0002287 31 0.229
protein modification by small protein conjugation or removal GO:0070647 207 0.216
nucleoside triphosphate metabolic process GO:0009141 230 0.209
purine nucleotide metabolic process GO:0006163 302 0.208
nucleoside metabolic process GO:0009116 246 0.195
purine nucleoside metabolic process GO:0042278 241 0.192
regulation of defense response to virus GO:0050688 18 0.189
protein ubiquitination GO:0016567 171 0.185
positive regulation of rig i signaling pathway GO:1900246 1 0.185
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.181
immune effector process GO:0002252 321 0.172
defense response to gram positive bacterium GO:0050830 50 0.161
nucleoside catabolic process GO:0009164 206 0.158
response to lipopolysaccharide GO:0032496 128 0.146
cellular response to lipid GO:0071396 145 0.145
protein modification by small protein conjugation GO:0032446 187 0.142
positive regulation of viral genome replication GO:0045070 2 0.135
purine nucleoside catabolic process GO:0006152 205 0.132
intracellular protein transport GO:0006886 204 0.131
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.131
negative regulation of viral process GO:0048525 23 0.122
rig i signaling pathway GO:0039529 4 0.122
regulation of defense response to bacterium GO:1900424 3 0.118
response to type i interferon GO:0034340 12 0.118
regulation of protein ubiquitination GO:0031396 52 0.117
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.111
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.109
negative regulation of cell proliferation GO:0008285 296 0.105
interspecies interaction between organisms GO:0044419 83 0.104
syncytium formation by plasma membrane fusion GO:0000768 42 0.103
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.101
positive regulation of interferon alpha production GO:0032727 4 0.100
cellular amino acid metabolic process GO:0006520 103 0.098
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.091
regulation of cytokine production GO:0001817 266 0.089
nucleocytoplasmic transport GO:0006913 139 0.085
interferon alpha production GO:0032607 7 0.083
cellular response to molecule of bacterial origin GO:0071219 83 0.082
negative regulation of protein metabolic process GO:0051248 282 0.077
regulation of t cell activation GO:0050863 170 0.077
negative regulation of cytoplasmic transport GO:1903650 29 0.075
organonitrogen compound catabolic process GO:1901565 264 0.072
cytokine production GO:0001816 319 0.072
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.068
negative regulation of protein modification process GO:0031400 163 0.067
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.067
negative regulation of intracellular protein transport GO:0090317 27 0.065
intracellular transport of virus GO:0075733 1 0.065
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.064
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.062
positive regulation of defense response GO:0031349 124 0.061
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.060
movement in host environment GO:0052126 15 0.058
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.057
regulation of natural killer cell mediated immunity GO:0002715 19 0.054
regulation of intracellular protein transport GO:0033157 82 0.053
protein import GO:0017038 101 0.053
regulation of viral genome replication GO:0045069 13 0.052
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.052
regulation of cytoplasmic transport GO:1903649 112 0.051
skin development GO:0043588 220 0.050
type i interferon production GO:0032606 29 0.048
negative regulation of cytokine production GO:0001818 84 0.048
myeloid leukocyte differentiation GO:0002573 119 0.048
regulation of rig i signaling pathway GO:0039535 2 0.047
cellular ketone metabolic process GO:0042180 84 0.046
negative regulation of intracellular transport GO:0032387 38 0.045
inflammatory response GO:0006954 244 0.044
regulation of intracellular transport GO:0032386 159 0.043
iron ion import into cell GO:0097459 4 0.042
viral life cycle GO:0019058 36 0.042
positive regulation of innate immune response GO:0045089 80 0.041
response to phenylpropanoid GO:0080184 22 0.041
regulation of reactive oxygen species metabolic process GO:2000377 40 0.041
regulation of type i interferon production GO:0032479 22 0.041
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.040
regulation of cell killing GO:0031341 40 0.040
innate immune response activating signal transduction GO:0002758 50 0.040
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.039
regulation of protein transport GO:0051223 163 0.039
negative regulation of immune system process GO:0002683 209 0.039
pattern recognition receptor signaling pathway GO:0002221 47 0.037
syncytium formation GO:0006949 43 0.036
heterocycle catabolic process GO:0046700 280 0.035
response to organic cyclic compound GO:0014070 198 0.034
negative regulation of viral transcription GO:0032897 3 0.034
response to stilbenoid GO:0035634 22 0.033
regulation of hormone levels GO:0010817 211 0.033
protein localization to organelle GO:0033365 185 0.033
covalent chromatin modification GO:0016569 163 0.033
establishment of protein localization to organelle GO:0072594 118 0.033
immunoglobulin mediated immune response GO:0016064 69 0.032
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.032
negative regulation of phosphorylation GO:0042326 166 0.031
t cell activation GO:0042110 289 0.030
cation transport GO:0006812 399 0.030
mda 5 signaling pathway GO:0039530 1 0.029
t helper 2 cell cytokine production GO:0035745 4 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.028
methylation GO:0032259 134 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.027
response to molecule of bacterial origin GO:0002237 143 0.027
regulation of protein targeting GO:1903533 61 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
regulation of hydrolase activity GO:0051336 246 0.025
cellular amine metabolic process GO:0044106 44 0.025
t cell lineage commitment GO:0002360 13 0.025
positive regulation of adaptive immune response GO:0002821 61 0.025
cellular response to lipopolysaccharide GO:0071222 77 0.025
fatty acid metabolic process GO:0006631 121 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
regulation of proteolysis GO:0030162 164 0.024
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.024
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
cellular response to biotic stimulus GO:0071216 92 0.024
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.024
cytokine mediated signaling pathway GO:0019221 115 0.024
t helper 17 cell lineage commitment GO:0072540 4 0.023
leukocyte mediated immunity GO:0002443 174 0.023
leukocyte activation involved in immune response GO:0002366 126 0.023
protein import into nucleus GO:0006606 95 0.023
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.023
adaptive immune response GO:0002250 155 0.022
ossification GO:0001503 216 0.022
myotube differentiation GO:0014902 105 0.022
protein localization to nucleus GO:0034504 121 0.022
production of molecular mediator of immune response GO:0002440 103 0.021
b cell mediated immunity GO:0019724 71 0.021
negative regulation of defense response GO:0031348 77 0.021
regulation of cell cycle GO:0051726 281 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
regulation of interferon gamma production GO:0032649 57 0.021
regulation of lymphocyte activation GO:0051249 240 0.020
muscle tissue development GO:0060537 308 0.020
regulation of t cell mediated immunity GO:0002709 34 0.020
negative regulation of molecular function GO:0044092 258 0.020
regulation of adaptive immune response GO:0002819 90 0.019
blood vessel morphogenesis GO:0048514 285 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
negative regulation of binding GO:0051100 39 0.019
cell fate commitment GO:0045165 210 0.019
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.019
dna metabolic process GO:0006259 303 0.019
response to dsrna GO:0043331 30 0.019
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.019
protein targeting GO:0006605 143 0.019
negative regulation of protein ubiquitination GO:0031397 19 0.019
response to organonitrogen compound GO:0010243 246 0.018
leukocyte differentiation GO:0002521 342 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of lymphocyte mediated immunity GO:0002706 84 0.018
maintenance of location GO:0051235 89 0.018
citrate metabolic process GO:0006101 3 0.018
nuclear transport GO:0051169 139 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
negative regulation of hydrolase activity GO:0051346 71 0.018
positive regulation of cell killing GO:0031343 33 0.018
natural killer cell mediated immunity GO:0002228 29 0.018
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.018
positive regulation of cytokine production GO:0001819 174 0.018
regulation of multi organism process GO:0043900 111 0.018
regulation of innate immune response GO:0045088 91 0.018
regulation of toll like receptor signaling pathway GO:0034121 20 0.017
alpha beta t cell activation GO:0046631 91 0.017
cytoplasmic transport GO:0016482 234 0.017
histone acetylation GO:0016573 41 0.017
leukocyte mediated cytotoxicity GO:0001909 62 0.017
regulation of homeostatic process GO:0032844 182 0.017
nuclear import GO:0051170 95 0.017
natural killer cell mediated cytotoxicity GO:0042267 29 0.016
sequestering of calcium ion GO:0051208 18 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
isg15 protein conjugation GO:0032020 4 0.016
positive regulation of cell death GO:0010942 224 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
leukocyte proliferation GO:0070661 172 0.016
lymphocyte differentiation GO:0030098 242 0.016
regulation of binding GO:0051098 111 0.015
viral gene expression GO:0019080 3 0.015
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.015
positive regulation of response to cytokine stimulus GO:0060760 11 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
negative regulation of protein binding GO:0032091 17 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
positive regulation of proteolysis GO:0045862 85 0.014
t cell mediated cytotoxicity GO:0001913 26 0.014
negative regulation of protein transport GO:0051224 46 0.014
natural killer cell proliferation GO:0001787 3 0.014
cellular homeostasis GO:0019725 240 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
carbohydrate metabolic process GO:0005975 230 0.014
macromolecule methylation GO:0043414 120 0.014
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
negative regulation of interferon beta production GO:0032688 3 0.014
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.013
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.013
protein maturation GO:0051604 176 0.013
antimicrobial peptide production GO:0002775 2 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
macromolecule catabolic process GO:0009057 281 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
cellular lipid metabolic process GO:0044255 323 0.013
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.013
developmental maturation GO:0021700 193 0.013
antimicrobial peptide biosynthetic process GO:0002777 2 0.013
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
amide transport GO:0042886 138 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
gland development GO:0048732 330 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.012
interferon gamma mediated signaling pathway GO:0060333 5 0.012
metal ion homeostasis GO:0055065 189 0.012
compound eye development GO:0048749 1 0.012
t cell differentiation GO:0030217 174 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
regulation of skeletal muscle fiber development GO:0048742 36 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.012
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.012
regulation of dna binding GO:0051101 39 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
neutrophil mediated killing of fungus GO:0070947 3 0.012
muscle cell development GO:0055001 133 0.012
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.012
cell adhesion GO:0007155 329 0.012
gliogenesis GO:0042063 141 0.012
isotype switching GO:0045190 36 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of myoblast differentiation GO:0045661 29 0.011
regulation of monocyte chemotaxis GO:0090025 3 0.011
stem cell development GO:0048864 219 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
positive regulation of leukocyte mediated immunity GO:0002705 70 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of organelle organization GO:0033043 289 0.011
negative regulation of innate immune response GO:0045824 17 0.011
leukocyte migration GO:0050900 124 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
internal protein amino acid acetylation GO:0006475 42 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.011
cation homeostasis GO:0055080 212 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
chromatin organization GO:0006325 206 0.011
negative regulation of cell motility GO:2000146 61 0.011
peptidyl amino acid modification GO:0018193 336 0.010
histone modification GO:0016570 159 0.010
rho protein signal transduction GO:0007266 32 0.010
sulfur compound metabolic process GO:0006790 100 0.010
fat cell differentiation GO:0045444 160 0.010
regulation of cell migration GO:0030334 219 0.010
t cell proliferation GO:0042098 120 0.010
multi multicellular organism process GO:0044706 109 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
sequestering of metal ion GO:0051238 19 0.010

Tgtp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org