|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.982
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.981
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.975
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.975
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.973
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.972
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.951
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.951
|
Rat |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.940
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.938
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.937
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.932
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.918
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.909
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.901
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.898
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.892
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.889
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.885
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.883
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.881
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.876
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.865
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.856
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.853
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.853
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.844
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.842
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.831
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.831
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.830
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.828
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.828
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.818
|
Rat |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.797
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.792
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.785
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.780
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.775
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.768
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.765
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.742
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.739
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.738
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.731
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.730
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.729
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.722
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.722
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.719
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.715
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.707
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.698
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.691
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.688
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.687
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.684
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.684
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.658
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.655
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.654
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.654
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.653
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.652
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.648
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.646
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.646
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.645
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.642
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.636
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.636
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.632
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.627
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.615
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.609
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.598
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.585
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.582
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.580
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.575
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.574
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.573
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.568
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.564
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.564
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.557
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.554
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.538
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.532
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.507
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.506
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.505
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.501
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.500
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.471
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.469
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.467
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.466
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.466
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.464
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.461
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.460
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.456
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.456
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.455
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.453
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.449
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.446
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.444
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.444
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.442
|
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.441
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.435
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.434
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.434
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.432
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.432
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.429
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.428
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.426
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.425
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.415
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.411
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.411
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.407
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.406
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.404
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.402
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.400
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.399
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.392
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.390
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.387
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.386
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.386
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.380
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.376
|
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.376
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.374
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.372
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.364
|
|
|
|
natural killer cell chemotaxis
|
GO:0035747 |
1 |
0.357
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.356
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.352
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.352
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.352
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.351
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.350
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.350
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.349
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.340
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.331
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.326
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.324
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.322
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.321
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.319
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.318
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.317
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.316
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.314
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.314
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.312
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.309
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.308
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.308
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.306
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.302
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.301
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.299
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.297
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.297
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.295
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.293
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.288
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.286
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.285
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.282
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.279
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.278
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.274
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.274
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.271
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.270
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.270
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.269
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.267
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.267
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.266
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.265
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.260
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.257
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.256
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
10 |
0.254
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.252
|
|
|
|
regulation of interleukin 4 production
|
GO:0032673 |
18 |
0.250
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.250
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.250
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.247
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.245
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.241
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.240
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.237
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
6 |
0.237
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.233
|
|
|
|
b cell chemotaxis
|
GO:0035754 |
3 |
0.230
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.229
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.229
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.228
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.227
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.225
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.224
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.224
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.224
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.223
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.222
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.221
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.220
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.219
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.217
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.217
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.216
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.215
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.214
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.213
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.212
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.212
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.212
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.212
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.211
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.210
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.209
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.208
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.207
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.206
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.206
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.204
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
20 |
0.203
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.203
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.199
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.198
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.198
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.197
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.197
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.196
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.193
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.193
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.192
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.191
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.191
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.190
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.190
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.190
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.190
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.190
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.189
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.189
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.189
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.187
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.185
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.185
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.184
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.184
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.183
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.181
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.181
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.180
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.179
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.179
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.179
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.179
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.176
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.176
|
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.174
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.174
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.173
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.172
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.171
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.171
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.170
|
|
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.169
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.169
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.168
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.167
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.167
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.167
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.166
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.166
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.164
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.164
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.163
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.163
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.163
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.162
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.162
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.162
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.162
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.158
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.157
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.156
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.155
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.152
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.152
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.152
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.148
|
|
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.148
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.146
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.146
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.145
|
|
|
|
macrophage apoptotic process
|
GO:0071888 |
7 |
0.144
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.144
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.143
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.143
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.143
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.141
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.141
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.140
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.140
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.139
|
|
|
|
regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000561 |
2 |
0.139
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.139
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.138
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.138
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.136
|
|
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.133
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.132
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.132
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.131
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.131
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.130
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.130
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.130
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.129
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.129
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.128
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.128
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.128
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.127
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.126
|
|
|
|
positive regulation of glycoprotein metabolic process
|
GO:1903020 |
6 |
0.125
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.124
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.124
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.124
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.124
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.123
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.123
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.122
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
5 |
0.121
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.121
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.120
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.118
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.117
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.116
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.116
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.115
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.115
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.114
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.114
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.113
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.113
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.113
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.111
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.111
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.110
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.109
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.109
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.109
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.109
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.109
|
|
|
|
gamma delta t cell lineage commitment
|
GO:0002365 |
1 |
0.108
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.108
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.108
|
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.108
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.108
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.107
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.106
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.106
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.105
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.105
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.105
|
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.104
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.104
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.103
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.103
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.103
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.103
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.102
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.101
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.101
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.100
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.100
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.100
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.099
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.099
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.098
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.097
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.097
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.097
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.096
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.096
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.096
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.096
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.096
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.095
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.093
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.092
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.092
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.091
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.091
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.090
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.090
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.090
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.089
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.089
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.089
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.089
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.088
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.088
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.088
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.087
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.087
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.087
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.087
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.086
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.086
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.086
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.084
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.084
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.084
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.084
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.083
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.083
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.083
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.082
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.082
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.082
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.082
|
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.082
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.082
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.081
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.081
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.080
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.080
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.080
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.079
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.078
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.078
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.078
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.078
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.077
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.077
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.077
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.076
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.076
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.076
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.075
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.075
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.074
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.074
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.074
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.074
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.074
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.073
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.073
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.073
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.073
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.073
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.073
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.073
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.072
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.072
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.071
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.071
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.071
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.070
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.070
|
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.070
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.070
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.070
|
|
|
|
positive regulation of glycoprotein biosynthetic process
|
GO:0010560 |
6 |
0.069
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.069
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.068
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.067
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.067
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.067
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.067
|
|
|
|
regulation of glycoprotein biosynthetic process
|
GO:0010559 |
12 |
0.066
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.066
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.066
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
5 |
0.065
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.065
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.063
|
|
