IMP

Process View

Mus musculus

21 genes annotated in mouse

regulation of t cell receptor signaling pathway

Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t cell receptor signaling pathway"

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Name	Description	Probability	Func Analog Organism
Ptprc	protein tyrosine phosphatase, receptor type, C	0.906
Ikzf1	IKAROS family zinc finger 1	0.859
Inpp5d	inositol polyphosphate-5-phosphatase D	0.752
Foxp3	forkhead box P3	0.698
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.345	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.332
Grb2	growth factor receptor bound protein 2	0.293
Lyz2	lysozyme 2	0.259
Tcra	T-cell receptor alpha chain	0.232
Lat	linker for activation of T cells	0.231
Cd80	CD80 antigen	0.205
Cd247	CD247 antigen	0.197
Il2rg	interleukin 2 receptor, gamma chain	0.194
Tnf	tumor necrosis factor	0.167
Rc3h1	RING CCCH (C3H) domains 1	0.153
Ifng	interferon gamma	0.153
Cd4	CD4 antigen	0.146
Cdh5	cadherin 5	0.142
Cd44	CD44 antigen	0.129
Itk	IL2-inducible T-cell kinase	0.122
Cd7	CD7 antigen	0.110
Cbl	Casitas B-lineage lymphoma	0.109	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.104	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.103
Jak2	Janus kinase 2	0.103
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.093
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.092
Pdcd1	programmed cell death 1	0.092
Stat3	signal transducer and activator of transcription 3	0.087
Prdm1	PR domain containing 1, with ZNF domain	0.087
Il2rb	interleukin 2 receptor, beta chain	0.086
Il4	interleukin 4	0.085
Icos	inducible T-cell co-stimulator	0.084
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.081
Was	Wiskott-Aldrich syndrome homolog (human)	0.080
Itgal	integrin alpha L	0.079
Il10	interleukin 10	0.078
Cd19	CD19 antigen	0.078
Tnip1	TNFAIP3 interacting protein 1	0.076
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.074
Vav1	vav 1 oncogene	0.073
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.071
Cxcl12	chemokine (C-X-C motif) ligand 12	0.068
Xcr1	chemokine (C motif) receptor 1	0.067	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.064
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.064
Cd5	CD5 antigen	0.063
Csf1	colony stimulating factor 1 (macrophage)	0.062
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.061
Cd96	CD96 antigen	0.060
Lck	lymphocyte protein tyrosine kinase	0.060
Fyn	Fyn proto-oncogene	0.058	Mouse
Cd8a	CD8 antigen, alpha chain	0.054
Ncr1	natural cytotoxicity triggering receptor 1	0.054
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.051
Il7r	interleukin 7 receptor	0.051
Cd2	CD2 antigen	0.051
Sykb	spleen tyrosine kinase	0.049
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.049
Fas	Fas (TNF receptor superfamily member 6)	0.048
Flt1	FMS-like tyrosine kinase 1	0.047
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.046
Fasl	Fas ligand (TNF superfamily, member 6)	0.041
Cd3e	CD3 antigen, epsilon polypeptide	0.041
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.041
Card11	caspase recruitment domain family, member 11	0.040
Tbx21	T-box 21	0.040
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.039
Ccl3	chemokine (C-C motif) ligand 3	0.039
Traf6	TNF receptor-associated factor 6	0.038
Trp53	transformation related protein 53	0.037
Myd88	myeloid differentiation primary response gene 88	0.037
Itgax	integrin alpha X	0.037
Slamf6	SLAM family member 6	0.036
Il18rap	interleukin 18 receptor accessory protein	0.036
Foxn1	forkhead box N1	0.036
Cybb	cytochrome b-245, beta polypeptide	0.035
Cd22	CD22 antigen	0.034
Fcrla	Fc receptor-like A	0.034
Stat1	signal transducer and activator of transcription 1	0.034
Pou2af1	POU domain, class 2, associating factor 1	0.033
Cldn4	claudin 4	0.033
Cd8b1	CD8 antigen, beta chain 1	0.033
Il27ra	interleukin 27 receptor, alpha	0.033
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.033
Tlr2	toll-like receptor 2	0.032
Rab25	RAB25, member RAS oncogene family	0.032
Ikzf3	IKAROS family zinc finger 3	0.032
Cd180	CD180 antigen	0.032
Gpr132	G protein-coupled receptor 132	0.031
Sell	selectin, lymphocyte	0.031
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.030
Slfn2	schlafen 2	0.030
Cd28	CD28 antigen	0.030
Rel	reticuloendotheliosis oncogene	0.030
Cd6	CD6 antigen	0.030
App	amyloid beta (A4) precursor protein	0.030
Ccr5	chemokine (C-C motif) receptor 5	0.030	Mouse
Asprv1	aspartic peptidase, retroviral-like 1	0.030
Rasgrp1	RAS guanyl releasing protein 1	0.029
Nsf	N-ethylmaleimide sensitive fusion protein	0.029
Cd40	CD40 antigen	0.029
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.028
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.028
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.028
Socs1	suppressor of cytokine signaling 1	0.027
Il1b	interleukin 1 beta	0.027
Cstb	cystatin B	0.026
Tgfb1	transforming growth factor, beta 1	0.026
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.026
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.025
Lair1	leukocyte-associated Ig-like receptor 1	0.024
Grap2	GRB2-related adaptor protein 2	0.024
Clnk	cytokine-dependent hematopoietic cell linker	0.024
Tlr4	toll-like receptor 4	0.023
Ifnar1	interferon (alpha and beta) receptor 1	0.023
Mmp9	matrix metallopeptidase 9	0.023
S100a4	S100 calcium binding protein A4	0.023
Ccr7	chemokine (C-C motif) receptor 7	0.023
Cd38	CD38 antigen	0.023
Hcls1	hematopoietic cell specific Lyn substrate 1	0.022
Ctsw	cathepsin W	0.022
Gab2	growth factor receptor bound protein 2-associated protein 2	0.022
Cxcr2	chemokine (C-X-C motif) receptor 2	0.021	Mouse
Ccl20	chemokine (C-C motif) ligand 20	0.021
Zap70	zeta-chain (TCR) associated protein kinase	0.021
Ltb	lymphotoxin B	0.021
Ptpre	protein tyrosine phosphatase, receptor type, E	0.021
Itgb2	integrin beta 2	0.020
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.020
Sla	src-like adaptor	0.020
Gzmk	granzyme K	0.020
Ccr10	chemokine (C-C motif) receptor 10	0.020	Mouse
Il10ra	interleukin 10 receptor, alpha	0.020
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.020
Ncoa3	nuclear receptor coactivator 3	0.020
Il2ra	interleukin 2 receptor, alpha chain	0.020
Il6st	interleukin 6 signal transducer	0.019
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.019
Itga4	integrin alpha 4	0.019
Gab1	growth factor receptor bound protein 2-associated protein 1	0.019
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.019
Il22	interleukin 22	0.019
Jak1	Janus kinase 1	0.019
Cd160	CD160 antigen	0.019
Gimap7	GTPase, IMAP family member 7	0.018
Ifngr1	interferon gamma receptor 1	0.018
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.018
Sit1	suppression inducing transmembrane adaptor 1	0.018
S1pr4	sphingosine-1-phosphate receptor 4	0.018
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.018
Cdcp1	CUB domain containing protein 1	0.018
Ccr9	chemokine (C-C motif) receptor 9	0.018	Mouse
Ticam1	toll-like receptor adaptor molecule 1	0.018
Hmox1	heme oxygenase (decycling) 1	0.018
Tek	endothelial-specific receptor tyrosine kinase	0.018
Prkce	protein kinase C, epsilon	0.018
Jak3	Janus kinase 3	0.017
Cd3g	CD3 antigen, gamma polypeptide	0.017
Grxcr1	glutaredoxin, cysteine rich 1	0.017
Sh2d2a	SH2 domain protein 2A	0.017
Fyb	FYN binding protein	0.017
Mag	myelin-associated glycoprotein	0.017
Evi2a	ecotropic viral integration site 2a	0.017
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.017
Myo1f	myosin IF	0.016
Dnm1	dynamin 1	0.016
Myo7a	myosin VIIA	0.016
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.016
Oit1	oncoprotein induced transcript 1	0.016
Cldn7	claudin 7	0.016
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.016
Ccl5	chemokine (C-C motif) ligand 5	0.016
Fam83f	family with sequence similarity 83, member F	0.016
Bdkrb1	bradykinin receptor, beta 1	0.016
Sfpi1	SFFV proviral integration 1	0.016
Pla2g2d	phospholipase A2, group IID	0.016
Rasal3	RAS protein activator like 3	0.016
Gzmb	granzyme B	0.016
Ccr2	chemokine (C-C motif) receptor 2	0.015	Mouse
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.015
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.015
Ccr8	chemokine (C-C motif) receptor 8	0.015	Mouse
Rac2	RAS-related C3 botulinum substrate 2	0.015
Cxcr6	chemokine (C-X-C motif) receptor 6	0.015	Mouse
Ccr6	chemokine (C-C motif) receptor 6	0.015	Mouse
Hr	hairless	0.015
Gpr18	G protein-coupled receptor 18	0.015
Pcdh12	protocadherin 12	0.015
Cxcl13	chemokine (C-X-C motif) ligand 13	0.015
Ehf	ets homologous factor	0.015	Mouse
Blnk	B-cell linker	0.015
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.015
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	0.014
Spint1	serine protease inhibitor, Kunitz type 1	0.014
Casp8	caspase 8	0.014
Ncf4	neutrophil cytosolic factor 4	0.014
Fpr2	formyl peptide receptor 2	0.014
Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	0.014
Rgs14	regulator of G-protein signaling 14	0.014
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.014	Mouse
Sufu	suppressor of fused homolog (Drosophila)	0.014
Aplp2	amyloid beta (A4) precursor-like protein 2	0.014
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.014
Ccr3	chemokine (C-C motif) receptor 3	0.014	Mouse
Apoe	apolipoprotein E	0.014
Il15	interleukin 15	0.014
Lalba	lactalbumin, alpha	0.014
Tgfbr2	transforming growth factor, beta receptor II	0.014
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.014
Mapk13	mitogen-activated protein kinase 13	0.014
Ptprj	protein tyrosine phosphatase, receptor type, J	0.013
Pyhin1	pyrin and HIN domain family, member 1	0.013
Il1a	interleukin 1 alpha	0.013
Lta	lymphotoxin A	0.013
Pkp3	plakophilin 3	0.013
Efna1	ephrin A1	0.013
Traf3ip2	TRAF3 interacting protein 2	0.013
Bcl6	B-cell leukemia/lymphoma 6	0.013
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.013
Themis	thymocyte selection associated	0.013
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.013
Zfp36	zinc finger protein 36	0.013
Slfn1	schlafen 1	0.013
Il1rn	interleukin 1 receptor antagonist	0.013
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.013
Muc1	mucin 1, transmembrane	0.013
Itgb3	integrin beta 3	0.013
Nkg7	natural killer cell group 7 sequence	0.013
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.013
Il2	interleukin 2	0.013
Pax8	paired box gene 8	0.013
Prkcd	protein kinase C, delta	0.013
Il18r1	interleukin 18 receptor 1	0.012
Fcrl1	Fc receptor-like 1	0.012
Ubd	ubiquitin D	0.012
Gna15	guanine nucleotide binding protein, alpha 15	0.012
Tmprss2	transmembrane protease, serine 2	0.012
Cd3d	CD3 antigen, delta polypeptide	0.012
Met	met proto-oncogene	0.012
Kdr	kinase insert domain protein receptor	0.012
Ccl4	chemokine (C-C motif) ligand 4	0.012
Clec2i	C-type lectin domain family 2, member i	0.012
Klk6	kallikrein related-peptidase 6	0.012
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.012
Spn	sialophorin	0.012
Fut4	fucosyltransferase 4	0.012
Lcp2	lymphocyte cytosolic protein 2	0.012
Cd2ap	CD2-associated protein	0.012
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.012
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.012
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.012
Dynlt1b	dynein light chain Tctex-type 1D	0.012
Stat4	signal transducer and activator of transcription 4	0.012
Wipf1	WAS/WASL interacting protein family, member 1	0.012
Fam83h	family with sequence similarity 83, member H	0.012
Ciita	class II transactivator	0.012
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.011
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.011
Itgam	integrin alpha M	0.011
Sparcl1	SPARC-like 1	0.011
Nod2	nucleotide-binding oligomerization domain containing 2	0.011
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.011
Gcet2	germinal center expressed transcript 2	0.011
Tspan10	tetraspanin 10	0.011
Adamdec1	ADAM-like, decysin 1	0.011
Erbb2ip	Erbb2 interacting protein	0.011
Acvrl1	activin A receptor, type II-like 1	0.011
Edn3	endothelin 3	0.011
Expi	extracellular proteinase inhibitor	0.011
Ptpra	protein tyrosine phosphatase, receptor type, A	0.011
Niacr1	niacin receptor 1	0.011
Stat2	signal transducer and activator of transcription 2	0.011
Ly6d	lymphocyte antigen 6 complex, locus D	0.011
Nt5e	5' nucleotidase, ecto	0.011
Anxa1	annexin A1	0.011
Cnr2	cannabinoid receptor 2 (macrophage)	0.011
Icam1	intercellular adhesion molecule 1	0.011
Ostf1	osteoclast stimulating factor 1	0.010
Malt1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.010
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.010
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.010
Fbrs	fibrosin	0.010
Tgif1	TGFB-induced factor homeobox 1	0.010
Ly9	lymphocyte antigen 9	0.010
Rc3h2	ring finger and CCCH-type zinc finger domains 2	0.010	Mouse
Elf1	E74-like factor 1	0.010
Fndc1	fibronectin type III domain containing 1	0.010
Plcg2	phospholipase C, gamma 2	0.010
Nfe2	nuclear factor, erythroid derived 2	0.010
Pdgfb	platelet derived growth factor, B polypeptide	0.010
Il1r1	interleukin 1 receptor, type I	0.010
P2ry10	purinergic receptor P2Y, G-protein coupled 10	0.010
Fam3b	family with sequence similarity 3, member B	0.010
Fpr3	formyl peptide receptor 3	0.010
Crisp3	cysteine-rich secretory protein 3	0.010
Marcksl1	MARCKS-like 1	0.010
Irf4	interferon regulatory factor 4	0.010