Rattus norvegicus

0 known processes

Nhlh1

nescient helix loop helix 1

Nhlh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.141
response to oxygen levels GO:0070482 265 0.138
cellular component biogenesis GO:0044085 368 0.128
cellular cation homeostasis GO:0030003 180 0.105
muscle contraction GO:0006936 88 0.097
blood circulation GO:0008015 183 0.091
cellular metal ion homeostasis GO:0006875 172 0.084
muscle system process GO:0003012 115 0.082
sodium ion transport GO:0006814 82 0.079
cellular response to oxygen containing compound GO:1901701 386 0.076
Rat
inorganic cation transmembrane transport GO:0098662 202 0.074
circulatory system process GO:0003013 183 0.073
response to corticosteroid GO:0031960 235 0.072
regulation of ion transport GO:0043269 245 0.070
regulation of blood pressure GO:0008217 83 0.068
intracellular signal transduction GO:0035556 314 0.067
brain development GO:0007420 247 0.067
Rat
cellular component assembly GO:0022607 360 0.066
response to lipopolysaccharide GO:0032496 191 0.066
heart contraction GO:0060047 57 0.065
positive regulation of long term synaptic potentiation GO:1900273 4 0.063
response to metal ion GO:0010038 253 0.060
head development GO:0060322 247 0.060
Rat
cellular calcium ion homeostasis GO:0006874 160 0.058
calcium ion homeostasis GO:0055074 162 0.057
oxoacid metabolic process GO:0043436 290 0.057
divalent inorganic cation homeostasis GO:0072507 165 0.057
carboxylic acid metabolic process GO:0019752 289 0.057
chemical homeostasis GO:0048878 292 0.056
Rat
cellular lipid metabolic process GO:0044255 208 0.054
positive regulation of transport GO:0051050 245 0.053
response to decreased oxygen levels GO:0036293 237 0.052
cation transmembrane transport GO:0098655 263 0.051
inorganic ion transmembrane transport GO:0098660 229 0.051
g protein coupled receptor signaling pathway GO:0007186 242 0.050
response to estrogen GO:0043627 232 0.050
response to inorganic substance GO:0010035 377 0.049
cellular divalent inorganic cation homeostasis GO:0072503 162 0.049
regulation of hormone levels GO:0010817 187 0.048
monovalent inorganic cation transport GO:0015672 172 0.048
ion homeostasis GO:0050801 212 0.047
glutamate receptor signaling pathway GO:0007215 43 0.047
cellular chemical homeostasis GO:0055082 247 0.047
Rat
hair cell differentiation GO:0035315 2 0.046
positive regulation of signaling GO:0023056 270 0.045
response to histamine GO:0034776 3 0.043
cation homeostasis GO:0055080 195 0.042
regulation of system process GO:0044057 208 0.042
cardiac muscle contraction GO:0060048 27 0.042
regulation of muscle contraction GO:0006937 53 0.041
multicellular organism reproduction GO:0032504 233 0.041
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.041
positive regulation of cell communication GO:0010647 271 0.041
organophosphate biosynthetic process GO:0090407 143 0.040
response to molecule of bacterial origin GO:0002237 194 0.039
cell activation GO:0001775 97 0.039
transmembrane transport GO:0055085 412 0.039
learning or memory GO:0007611 90 0.037
macromolecular complex subunit organization GO:0043933 339 0.036
negative regulation of cell death GO:0060548 229 0.035
Rat
response to peptide GO:1901652 292 0.035
reproductive system development GO:0061458 128 0.034
cellular ion homeostasis GO:0006873 184 0.034
cytosolic calcium ion homeostasis GO:0051480 140 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
Human Rat
positive regulation of developmental process GO:0051094 283 0.034
Rat
cellular response to endogenous stimulus GO:0071495 377 0.034
response to other organism GO:0051707 220 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
Rat
regulation of metal ion transport GO:0010959 118 0.033
response to ethanol GO:0045471 162 0.033
neuron differentiation GO:0030182 368 0.033
Rat
hormone transport GO:0009914 121 0.033
protein complex biogenesis GO:0070271 263 0.033
regulation of synaptic transmission GO:0050804 141 0.032
protein complex assembly GO:0006461 263 0.032
regulation of nervous system development GO:0051960 264 0.032
Rat
synaptic transmission glycinergic GO:0060012 2 0.032
organophosphate metabolic process GO:0019637 370 0.032
response to bacterium GO:0009617 200 0.032
ion transmembrane transport GO:0034220 365 0.032
homeostatic process GO:0042592 331 0.031
Rat
regulation of apoptotic process GO:0042981 335 0.031
Rat
secretion by cell GO:0032940 248 0.030
response to hypoxia GO:0001666 231 0.030
cellular homeostasis GO:0019725 252 0.030
Rat
organic acid metabolic process GO:0006082 292 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
heart process GO:0003015 57 0.030
central nervous system development GO:0007417 311 0.030
Rat
single organism biosynthetic process GO:0044711 342 0.029
sequestering of metal ion GO:0051238 9 0.029
response to toxic substance GO:0009636 133 0.029
regulation of signal transduction GO:0009966 318 0.029
cellular response to histamine GO:0071420 3 0.029
response to external biotic stimulus GO:0043207 221 0.029
anion transport GO:0006820 178 0.029
regulation of neurogenesis GO:0050767 247 0.029
Rat
neurological system process GO:0050877 219 0.028
positive regulation of nervous system development GO:0051962 178 0.028
Rat
response to radiation GO:0009314 137 0.027
response to extracellular stimulus GO:0009991 380 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
response to mechanical stimulus GO:0009612 134 0.027
rhythmic process GO:0048511 156 0.027
regulation of blood circulation GO:1903522 110 0.027
cellular ketone metabolic process GO:0042180 51 0.027
response to glucocorticoid GO:0051384 223 0.026
regulation of molecular function GO:0065009 398 0.026
macromolecular complex assembly GO:0065003 273 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
regulation of membrane potential GO:0042391 110 0.026
apoptotic process GO:0006915 381 0.026
Rat
regulation of peptide secretion GO:0002791 82 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
response to peptide hormone GO:0043434 278 0.025
protein complex subunit organization GO:0071822 302 0.025
response to insulin GO:0032868 133 0.025
regulation of protein metabolic process GO:0051246 289 0.025
neuronal ion channel clustering GO:0045161 3 0.025
metal ion transport GO:0030001 289 0.025
immune system process GO:0002376 204 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
synaptic transmission GO:0007268 235 0.024
ras protein signal transduction GO:0007265 29 0.024
neuromuscular process GO:0050905 2 0.024
calcium ion transport GO:0006816 131 0.024
single organism reproductive process GO:0044702 297 0.024
cell growth GO:0016049 104 0.023
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.023
striated muscle contraction GO:0006941 44 0.023
axis specification GO:0009798 4 0.023
regulation of secretion by cell GO:1903530 208 0.023
urogenital system development GO:0001655 78 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
regulation of cellular component organization GO:0051128 368 0.022
inner ear development GO:0048839 21 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
Rat
negative regulation of secretion GO:0051048 82 0.022
positive regulation of synaptic transmission GO:0050806 62 0.022
protein heterooligomerization GO:0051291 89 0.022
cellular amine metabolic process GO:0044106 38 0.021
regulation of peptide transport GO:0090087 87 0.021
forebrain development GO:0030900 98 0.021
Rat
behavior GO:0007610 205 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
response to ketone GO:1901654 182 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
cellular response to lipid GO:0071396 201 0.021
defense response GO:0006952 194 0.021
response to cytokine GO:0034097 215 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
regulation of muscle system process GO:0090257 79 0.020
purine containing compound biosynthetic process GO:0072522 85 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
divalent metal ion transport GO:0070838 132 0.020
mechanoreceptor differentiation GO:0042490 2 0.020
sensory perception GO:0007600 101 0.020
urinary bladder smooth muscle contraction GO:0014832 4 0.020
purine nucleotide biosynthetic process GO:0006164 83 0.019
phospholipid metabolic process GO:0006644 61 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
Human Rat
response to camp GO:0051591 91 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
Rat
sequestering of calcium ion GO:0051208 8 0.019
regulation of cellular component movement GO:0051270 150 0.018
peptide secretion GO:0002790 86 0.018
hormone secretion GO:0046879 115 0.018
secretion GO:0046903 307 0.018
regulation of calcium ion transport GO:0051924 77 0.018
regulation of cell development GO:0060284 263 0.018
Rat
neuron projection development GO:0031175 273 0.018
peptidyl amino acid modification GO:0018193 126 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
Rat
response to ammonium ion GO:0060359 71 0.018
regulation of phosphorylation GO:0042325 248 0.018
developmental growth GO:0048589 100 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
single organism behavior GO:0044708 130 0.018
reproduction GO:0000003 245 0.018
telencephalon development GO:0021537 62 0.018
gliogenesis GO:0042063 93 0.017
memory GO:0007613 54 0.017
cardiac muscle cell contraction GO:0086003 10 0.017
organ formation GO:0048645 3 0.017
regulation of protein transport GO:0051223 68 0.017
regulation of heart contraction GO:0008016 48 0.017
anterior posterior pattern specification GO:0009952 1 0.017
cell cell signaling GO:0007267 335 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
neuron death GO:0070997 127 0.017
regulation of smooth muscle contraction GO:0006940 29 0.017
response to wounding GO:0009611 254 0.017
regulation of peptide hormone secretion GO:0090276 80 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
amine metabolic process GO:0009308 38 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
peptide transport GO:0015833 97 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
Rat
positive regulation of molecular function GO:0044093 230 0.016
sodium ion transmembrane transport GO:0035725 67 0.016
reproductive process GO:0022414 372 0.016
response to oxidative stress GO:0006979 186 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
positive regulation of kinase activity GO:0033674 77 0.016
regulation of catalytic activity GO:0050790 304 0.016
regulation of synaptic plasticity GO:0048167 70 0.016
cellular response to biotic stimulus GO:0071216 59 0.015
programmed cell death GO:0012501 392 0.015
Rat
glycerolipid metabolic process GO:0046486 67 0.015
single organism organelle organization GO:1902589 180 0.015
negative regulation of vesicle fusion GO:0031339 2 0.015
regulation of cellular localization GO:0060341 263 0.015
muscle cell proliferation GO:0033002 84 0.015
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.015
cellular catabolic process GO:0044248 295 0.015
amide transport GO:0042886 105 0.015
signal release GO:0023061 145 0.015
leukocyte migration GO:0050900 38 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
Rat
protein localization GO:0008104 191 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
Rat
regulation of systemic arterial blood pressure GO:0003073 30 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
cellular response to stress GO:0033554 269 0.015
multi organism reproductive process GO:0044703 262 0.015
response to nutrient levels GO:0031667 370 0.015
regulation of cell proliferation GO:0042127 359 0.015
Rat
regulation of homeostatic process GO:0032844 101 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
regulation of cell projection organization GO:0031344 175 0.015
regulation of potassium ion transport GO:0043266 29 0.014
transmission of nerve impulse GO:0019226 42 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
protein oligomerization GO:0051259 191 0.014
eye morphogenesis GO:0048592 4 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
peptide hormone secretion GO:0030072 84 0.014
negative regulation of metabolic process GO:0009892 331 0.014
proteolysis GO:0006508 175 0.014
regulation of ion homeostasis GO:2000021 63 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
developmental process involved in reproduction GO:0003006 159 0.014
divalent inorganic cation transport GO:0072511 134 0.014
cell projection morphogenesis GO:0048858 123 0.013
cellular response to oxygen levels GO:0071453 60 0.013
positive regulation of organelle organization GO:0010638 48 0.013
regulation of cell growth GO:0001558 85 0.013
ovulation cycle GO:0042698 67 0.013
cardiac conduction GO:0061337 2 0.013
cellular response to hypoxia GO:0071456 51 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
positive regulation of cell development GO:0010720 176 0.013
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
urinary tract smooth muscle contraction GO:0014848 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
inner ear receptor cell differentiation GO:0060113 2 0.013
regulation of neurological system process GO:0031644 43 0.012
purine containing compound metabolic process GO:0072521 253 0.012
phosphatidylinositol dephosphorylation GO:0046856 4 0.012
circadian sleep wake cycle sleep GO:0050802 21 0.012
adult locomotory behavior GO:0008344 4 0.012
circadian regulation of gene expression GO:0032922 3 0.012
response to progesterone GO:0032570 48 0.012
regulation of neuron differentiation GO:0045664 208 0.012
Rat
response to monosaccharide GO:0034284 159 0.012
Rat
muscle tissue development GO:0060537 58 0.012
sensory perception of bitter taste GO:0050913 4 0.012
regulation of body fluid levels GO:0050878 90 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
response to amine GO:0014075 46 0.012
regulation of inflammatory response GO:0050727 48 0.012
regulation of insulin secretion GO:0050796 65 0.012
placenta development GO:0001890 22 0.012
regulation of cell migration GO:0030334 128 0.011
regulation of response to external stimulus GO:0032101 106 0.011
second messenger mediated signaling GO:0019932 51 0.011
growth GO:0040007 165 0.011
positive regulation of growth GO:0045927 55 0.011
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.011
peristalsis GO:0030432 2 0.011
acute inflammatory response GO:0002526 58 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
Human Rat
regulation of transmembrane transport GO:0034762 122 0.011
saliva secretion GO:0046541 3 0.011
regulation of behavior GO:0050795 61 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
regulation of anatomical structure size GO:0090066 135 0.011
regulation of neuron projection development GO:0010975 161 0.011
salivary gland development GO:0007431 3 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
rho protein signal transduction GO:0007266 11 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
response to alkaloid GO:0043279 132 0.011
nucleotide metabolic process GO:0009117 279 0.011
regulation of hormone secretion GO:0046883 106 0.011
synapse organization GO:0050808 46 0.011
response to vitamin GO:0033273 131 0.011
response to acid chemical GO:0001101 222 0.011
regulation of programmed cell death GO:0043067 341 0.010
Rat
heart morphogenesis GO:0003007 3 0.010
rna localization GO:0006403 4 0.010
establishment of protein localization GO:0045184 141 0.010
regulation of response to stress GO:0080134 126 0.010
feeding behavior GO:0007631 53 0.010
cellular response to molecule of bacterial origin GO:0071219 56 0.010
negative regulation of transport GO:0051051 136 0.010
positive regulation of renin secretion into blood stream GO:1900135 1 0.010
response to growth factor GO:0070848 189 0.010
Rat
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
neuron development GO:0048666 286 0.010
organic anion transport GO:0015711 132 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
positive regulation of blood pressure GO:0045777 31 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
regulation of secretion GO:0051046 224 0.010
embryonic axis specification GO:0000578 1 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
intracellular transport GO:0046907 185 0.010
Rat
central nervous system neuron development GO:0021954 5 0.010

Nhlh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
sensory system disease DOID:0050155 0 0.041
eye disease DOID:5614 0 0.037
eye and adnexa disease DOID:1492 0 0.037
urinary system disease DOID:18 0 0.012