Rattus norvegicus

35 known processes

Prdm4

PR domain containing 4

(Aliases: SC-1)

Prdm4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 289 0.132
macromolecular complex assembly GO:0065003 273 0.124
oxoacid metabolic process GO:0043436 290 0.108
regulation of transcription dna templated GO:0006355 374 0.108
regulation of phosphate metabolic process GO:0019220 349 0.097
carboxylic acid metabolic process GO:0019752 289 0.097
cellular component biogenesis GO:0044085 368 0.093
regulation of cellular protein metabolic process GO:0032268 267 0.087
regulation of rna biosynthetic process GO:2001141 381 0.081
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.074
regulation of nucleic acid templated transcription GO:1903506 380 0.072
organic acid metabolic process GO:0006082 292 0.071
cellular amino acid metabolic process GO:0006520 107 0.067
cell cycle GO:0007049 101 0.065
catabolic process GO:0009056 351 0.064
protein complex biogenesis GO:0070271 263 0.062
cellular response to endogenous stimulus GO:0071495 377 0.059
regulation of phosphorus metabolic process GO:0051174 349 0.057
programmed cell death GO:0012501 392 0.056
nucleotide metabolic process GO:0009117 279 0.054
single organism reproductive process GO:0044702 297 0.052
response to inorganic substance GO:0010035 377 0.051
regulation of cellular component organization GO:0051128 368 0.050
protein complex subunit organization GO:0071822 302 0.049
cellular macromolecule localization GO:0070727 122 0.048
developmental process involved in reproduction GO:0003006 159 0.047
protein phosphorylation GO:0006468 345 0.047
positive regulation of cellular component organization GO:0051130 200 0.045
proteolysis GO:0006508 175 0.045
rna biosynthetic process GO:0032774 380 0.044
reproductive process GO:0022414 372 0.044
anatomical structure morphogenesis GO:0009653 298 0.044
cytoskeleton organization GO:0007010 111 0.043
protein localization GO:0008104 191 0.042
b cell differentiation GO:0030183 2 0.041
regulation of molecular function GO:0065009 398 0.041
cellular cation homeostasis GO:0030003 180 0.041
multicellular organismal reproductive process GO:0048609 233 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
positive regulation of protein metabolic process GO:0051247 178 0.040
response to external biotic stimulus GO:0043207 221 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.039
organelle organization GO:0006996 266 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
cellular response to growth factor stimulus GO:0071363 162 0.038
regulation of cellular localization GO:0060341 263 0.038
regulation of hydrolase activity GO:0051336 143 0.037
positive regulation of protein modification process GO:0031401 142 0.037
cellular homeostasis GO:0019725 252 0.037
neuron differentiation GO:0030182 368 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
negative regulation of gene expression GO:0010629 199 0.036
secretion GO:0046903 307 0.036
organic substance catabolic process GO:1901575 316 0.036
positive regulation of cell communication GO:0010647 271 0.036
single organism catabolic process GO:0044712 283 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.036
multicellular organism reproduction GO:0032504 233 0.035
homeostatic process GO:0042592 331 0.035
regulation of protein modification process GO:0031399 194 0.035
regulation of protein phosphorylation GO:0001932 183 0.035
cellular amine metabolic process GO:0044106 38 0.034
rna metabolic process GO:0016070 406 0.034
regulation of programmed cell death GO:0043067 341 0.034
cellular component assembly GO:0022607 360 0.033
regulation of cell proliferation GO:0042127 359 0.033
reproduction GO:0000003 245 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
cell cell signaling GO:0007267 335 0.033
positive regulation of molecular function GO:0044093 230 0.032
single organism organelle organization GO:1902589 180 0.032
vesicle mediated transport GO:0016192 181 0.032
cellular ion homeostasis GO:0006873 184 0.032
regulation of catalytic activity GO:0050790 304 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.031
neurological system process GO:0050877 219 0.031
negative regulation of metabolic process GO:0009892 331 0.030
nucleic acid templated transcription GO:0097659 379 0.030
cellular component morphogenesis GO:0032989 155 0.029
sexual reproduction GO:0019953 148 0.029
single organism intracellular transport GO:1902582 166 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
intracellular transport GO:0046907 185 0.029
positive regulation of transport GO:0051050 245 0.029
regulation of organelle organization GO:0033043 80 0.029
regulation of apoptotic process GO:0042981 335 0.029
regulation of rna metabolic process GO:0051252 391 0.029
regulation of membrane potential GO:0042391 110 0.029
response to growth factor GO:0070848 189 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
protein complex assembly GO:0006461 263 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
intracellular signal transduction GO:0035556 314 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
cellular protein localization GO:0034613 122 0.027
secretion by cell GO:0032940 248 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
positive regulation of gene expression GO:0010628 244 0.027
response to radiation GO:0009314 137 0.026
reproductive structure development GO:0048608 128 0.026
positive regulation of cell development GO:0010720 176 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
cellular chemical homeostasis GO:0055082 247 0.026
axis specification GO:0009798 4 0.026
positive regulation of nervous system development GO:0051962 178 0.025
synaptic growth at neuromuscular junction GO:0051124 1 0.025
chemical homeostasis GO:0048878 292 0.025
muscle system process GO:0003012 115 0.025
cellular catabolic process GO:0044248 295 0.025
aromatic compound catabolic process GO:0019439 168 0.025
multi organism reproductive process GO:0044703 262 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
immune response GO:0006955 104 0.025
anion transport GO:0006820 178 0.024
negative regulation of protein metabolic process GO:0051248 114 0.024
cellular ketone metabolic process GO:0042180 51 0.024
regulation of cell development GO:0060284 263 0.024
response to purine containing compound GO:0014074 126 0.024
organophosphate metabolic process GO:0019637 370 0.024
membrane organization GO:0061024 94 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
synaptic transmission GO:0007268 235 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
reproductive system development GO:0061458 128 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
regulation of phosphorylation GO:0042325 248 0.023
multicellular organism growth GO:0035264 1 0.023
positive regulation of developmental process GO:0051094 283 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
cation homeostasis GO:0055080 195 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
regulation of neuron differentiation GO:0045664 208 0.022
cellular response to stress GO:0033554 269 0.022
regulation of signal transduction GO:0009966 318 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
leukocyte activation GO:0045321 76 0.022
peptidyl amino acid modification GO:0018193 126 0.022
development of primary sexual characteristics GO:0045137 107 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
response to monosaccharide GO:0034284 159 0.021
cell projection organization GO:0030030 302 0.021
muscle structure development GO:0061061 87 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
response to oxygen levels GO:0070482 265 0.021
response to hydrogen peroxide GO:0042542 89 0.021
behavior GO:0007610 205 0.021
ion transmembrane transport GO:0034220 365 0.021
cell motility GO:0048870 202 0.021
chromosome segregation GO:0007059 2 0.021
regulation of nervous system development GO:0051960 264 0.021
response to oxidative stress GO:0006979 186 0.021
defense response GO:0006952 194 0.021
response to camp GO:0051591 91 0.020
locomotion GO:0040011 237 0.020
aging GO:0007568 241 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
cell cycle checkpoint GO:0000075 2 0.020
growth GO:0040007 165 0.020
negative regulation of cell death GO:0060548 229 0.020
regulation of transferase activity GO:0051338 123 0.019
regulation of protein complex assembly GO:0043254 33 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
dephosphorylation GO:0016311 98 0.019
response to mechanical stimulus GO:0009612 134 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
wound healing GO:0042060 122 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
response to cytokine GO:0034097 215 0.019
ras protein signal transduction GO:0007265 29 0.019
response to temperature stimulus GO:0009266 94 0.019
developmental growth GO:0048589 100 0.019
cellular response to reactive oxygen species GO:0034614 55 0.019
tissue development GO:0009888 252 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of system process GO:0044057 208 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
peptidyl tyrosine phosphorylation GO:0018108 72 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.018
neuron projection development GO:0031175 273 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
response to peptide hormone GO:0043434 278 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
transmembrane transport GO:0055085 412 0.018
protein oligomerization GO:0051259 191 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
regulation of ion transport GO:0043269 245 0.018
amine metabolic process GO:0009308 38 0.018
regulation of cell differentiation GO:0045595 320 0.018
rhythmic process GO:0048511 156 0.018
regulation of secretion by cell GO:1903530 208 0.017
embryonic pattern specification GO:0009880 1 0.017
dna metabolic process GO:0006259 96 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
regulation of protein kinase activity GO:0045859 105 0.017
ion homeostasis GO:0050801 212 0.017
organ regeneration GO:0031100 101 0.017
cellular macromolecular complex assembly GO:0034622 58 0.016
response to nutrient levels GO:0031667 370 0.016
head development GO:0060322 247 0.016
response to extracellular stimulus GO:0009991 380 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
amide transport GO:0042886 105 0.016
apoptotic process GO:0006915 381 0.016
regulation of catabolic process GO:0009894 113 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
cellular response to lipid GO:0071396 201 0.016
actin filament based process GO:0030029 86 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
immune effector process GO:0002252 53 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.016
meiotic cell cycle process GO:1903046 3 0.015
response to hexose GO:0009746 144 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
response to ionizing radiation GO:0010212 59 0.015
regulation of cell projection organization GO:0031344 175 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
cellular modified amino acid metabolic process GO:0006575 61 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.015
mitotic cell cycle GO:0000278 49 0.015
organelle localization GO:0051640 55 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
response to reactive oxygen species GO:0000302 120 0.015
cellular protein catabolic process GO:0044257 19 0.015
protein heterooligomerization GO:0051291 89 0.015
response to glucose GO:0009749 136 0.015
protein transport GO:0015031 132 0.015
response to carbohydrate GO:0009743 183 0.015
neuron development GO:0048666 286 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
response to other organism GO:0051707 220 0.014
generation of precursor metabolites and energy GO:0006091 62 0.014
single organism behavior GO:0044708 130 0.014
positive regulation of cell death GO:0010942 184 0.014
multicellular organismal signaling GO:0035637 44 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
response to toxic substance GO:0009636 133 0.014
positive regulation of signal transduction GO:0009967 175 0.014
regulation of synaptic transmission GO:0050804 141 0.014
regulation of rab protein signal transduction GO:0032483 3 0.014
regulation of neurogenesis GO:0050767 247 0.014
spindle organization GO:0007051 2 0.014
chromosome organization GO:0051276 36 0.014
single organism cellular localization GO:1902580 102 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of anatomical structure size GO:0090066 135 0.014
cell cycle process GO:0022402 57 0.014
neuronal action potential GO:0019228 35 0.014
gamete generation GO:0007276 124 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
protein import into nucleus GO:0006606 35 0.014
carbohydrate metabolic process GO:0005975 130 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
positive regulation of signaling GO:0023056 270 0.013
mitotic cell cycle checkpoint GO:0007093 1 0.013
embryonic axis specification GO:0000578 1 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
metaphase anaphase transition of cell cycle GO:0044784 1 0.013
cellular response to external stimulus GO:0071496 118 0.013
positive regulation of transferase activity GO:0051347 81 0.013
establishment of protein localization GO:0045184 141 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.013
regulation of sister chromatid segregation GO:0033045 1 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to decreased oxygen levels GO:0036293 237 0.013
brain development GO:0007420 247 0.013
single organism biosynthetic process GO:0044711 342 0.013
regulation of secretion GO:0051046 224 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
transcription dna templated GO:0006351 377 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
response to peptide GO:1901652 292 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
protein maturation GO:0051604 68 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
macromolecule catabolic process GO:0009057 58 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
sex differentiation GO:0007548 113 0.012
microtubule organizing center organization GO:0031023 1 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.012
intracellular protein transport GO:0006886 79 0.012
tube development GO:0035295 89 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
modification dependent macromolecule catabolic process GO:0043632 14 0.012
regulation of neuron death GO:1901214 115 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
response to metal ion GO:0010038 253 0.012
regulation of b cell differentiation GO:0045577 1 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
response to alkaloid GO:0043279 132 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
myelination GO:0042552 39 0.012
positive regulation of ras gtpase activity GO:0032320 28 0.012
action potential GO:0001508 54 0.012
protein processing GO:0016485 68 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
negative regulation of molecular function GO:0044092 133 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.012
spermatogenesis GO:0007283 99 0.012
cell activation GO:0001775 97 0.011
regulation of dna metabolic process GO:0051052 60 0.011
response to ethanol GO:0045471 162 0.011
salivary gland development GO:0007431 3 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of neuron projection development GO:0010975 161 0.011
neuron projection morphogenesis GO:0048812 122 0.011
negative regulation of cell communication GO:0010648 158 0.011
cation transport GO:0006812 382 0.011
regulation of rab gtpase activity GO:0032313 3 0.011
ncrna processing GO:0034470 3 0.011
microtubule based process GO:0007017 36 0.011
cortical actin cytoskeleton organization GO:0030866 2 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
lipid modification GO:0030258 52 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
rna localization GO:0006403 4 0.011
regulation of nucleocytoplasmic transport GO:0046822 28 0.011
response to vitamin GO:0033273 131 0.011
response to nutrient GO:0007584 248 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
gastrulation GO:0007369 2 0.011
circadian regulation of gene expression GO:0032922 3 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
positive regulation of rna metabolic process GO:0051254 203 0.010
negative regulation of transport GO:0051051 136 0.010
somatic stem cell maintenance GO:0035019 2 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
regulation of proteolysis GO:0030162 66 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
regulation of body fluid levels GO:0050878 90 0.010
anterior posterior pattern specification GO:0009952 1 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
ubiquitin dependent protein catabolic process GO:0006511 14 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
regulation of embryonic development GO:0045995 2 0.010
smad protein complex assembly GO:0007183 1 0.010
metal ion homeostasis GO:0055065 186 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
gliogenesis GO:0042063 93 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
regulation of growth GO:0040008 105 0.010
purine containing compound metabolic process GO:0072521 253 0.010
actin cytoskeleton organization GO:0030036 73 0.010
response to bacterium GO:0009617 200 0.010
nucleoside metabolic process GO:0009116 179 0.010

Prdm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.011