Rattus norvegicus

41 known processes

Alas2

aminolevulinate, delta-, synthase 2

Alas2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hydrogen peroxide metabolic process GO:0042743 13 0.999
glutathione metabolic process GO:0006749 15 0.917
cellular amide metabolic process GO:0043603 44 0.915
oxygen transport GO:0015671 2 0.850
cellular component assembly GO:0022607 360 0.850
protein heterooligomerization GO:0051291 89 0.825
organic acid metabolic process GO:0006082 292 0.817
oxidation reduction process GO:0055114 304 0.780
cellular modified amino acid metabolic process GO:0006575 61 0.775
gas transport GO:0015669 4 0.750
carboxylic acid metabolic process GO:0019752 289 0.694
protein complex assembly GO:0006461 263 0.668
peptide metabolic process GO:0006518 32 0.636
cellular component biogenesis GO:0044085 368 0.629
protein oligomerization GO:0051259 191 0.601
oxoacid metabolic process GO:0043436 290 0.591
cellular response to oxidative stress GO:0034599 76 0.586
macromolecular complex assembly GO:0065003 273 0.562
myeloid cell development GO:0061515 1 0.529
macromolecular complex subunit organization GO:0043933 339 0.522
regulation of blood pressure GO:0008217 83 0.516
cellular response to stress GO:0033554 269 0.499
erythrocyte differentiation GO:0030218 1 0.481
regulation of translational initiation in response to stress GO:0043558 4 0.439
cellular response to hydrogen peroxide GO:0070301 42 0.434
protein complex subunit organization GO:0071822 302 0.430
protein complex biogenesis GO:0070271 263 0.415
negative regulation of blood pressure GO:0045776 29 0.414
sensory perception of pain GO:0019233 73 0.408
neurological system process GO:0050877 219 0.358
response to oxidative stress GO:0006979 186 0.330
homeostasis of number of cells GO:0048872 10 0.325
cellular response to oxygen containing compound GO:1901701 386 0.325
hematopoietic or lymphoid organ development GO:0048534 36 0.269
regulation of sensory perception of pain GO:0051930 29 0.260
cellular response to reactive oxygen species GO:0034614 55 0.225
reactive oxygen species metabolic process GO:0072593 37 0.201
myeloid cell differentiation GO:0030099 22 0.196
regulation of sensory perception GO:0051931 29 0.183
immune system development GO:0002520 41 0.172
cellular amino acid metabolic process GO:0006520 107 0.170
sensory perception GO:0007600 101 0.163
response to biotic stimulus GO:0009607 226 0.162
blood circulation GO:0008015 183 0.151
inorganic cation transmembrane transport GO:0098662 202 0.143
cellular component movement GO:0006928 248 0.139
single organism organelle organization GO:1902589 180 0.138
positive regulation of developmental process GO:0051094 283 0.125
granulocyte chemotaxis GO:0071621 15 0.122
cellular catabolic process GO:0044248 295 0.119
hepoxilin metabolic process GO:0051121 5 0.114
myeloid cell homeostasis GO:0002262 6 0.112
phosphatidylethanolamine metabolic process GO:0046337 1 0.107
regulation of cellular component organization GO:0051128 368 0.104
regulation of intracellular signal transduction GO:1902531 218 0.103
transmembrane transport GO:0055085 412 0.094
homeostatic process GO:0042592 331 0.093
response to inorganic substance GO:0010035 377 0.088
translational initiation GO:0006413 8 0.081
cell cell signaling GO:0007267 335 0.077
regulation of phosphate metabolic process GO:0019220 349 0.075
inorganic ion transmembrane transport GO:0098660 229 0.067
small molecule biosynthetic process GO:0044283 124 0.065
erythrocyte homeostasis GO:0034101 2 0.064
cation transmembrane transport GO:0098655 263 0.062
regulation of signal transduction GO:0009966 318 0.061
positive regulation of cellular protein metabolic process GO:0032270 167 0.061
cell motility GO:0048870 202 0.059
response to nutrient GO:0007584 248 0.057
regulation of rna metabolic process GO:0051252 391 0.055
regulation of phosphorus metabolic process GO:0051174 349 0.055
neuron development GO:0048666 286 0.054
organophosphate metabolic process GO:0019637 370 0.053
cell chemotaxis GO:0060326 31 0.053
circulatory system process GO:0003013 183 0.052
positive regulation of phosphate metabolic process GO:0045937 262 0.051
actin filament based process GO:0030029 86 0.049
positive regulation of molecular function GO:0044093 230 0.049
regulation of neuron projection development GO:0010975 161 0.048
ion transmembrane transport GO:0034220 365 0.048
regulation of translation in response to stress GO:0043555 5 0.047
regulation of multicellular organismal development GO:2000026 376 0.047
nitrogen compound transport GO:0071705 229 0.047
regeneration GO:0031099 163 0.046
regulation of system process GO:0044057 208 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
response to cytokine GO:0034097 215 0.044
intracellular signal transduction GO:0035556 314 0.044
neuron differentiation GO:0030182 368 0.043
synaptic transmission GO:0007268 235 0.043
hepoxilin biosynthetic process GO:0051122 5 0.043
programmed cell death GO:0012501 392 0.043
response to nutrient levels GO:0031667 370 0.043
organelle organization GO:0006996 266 0.042
negative regulation of apoptotic process GO:0043066 181 0.042
response to hydrogen peroxide GO:0042542 89 0.042
regulation of molecular function GO:0065009 398 0.042
regulation of translational initiation GO:0006446 6 0.042
secretion GO:0046903 307 0.042
response to monosaccharide GO:0034284 159 0.041
protein phosphorylation GO:0006468 345 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
nucleotide metabolic process GO:0009117 279 0.038
regulation of cell differentiation GO:0045595 320 0.037
cellular amine metabolic process GO:0044106 38 0.037
cell projection organization GO:0030030 302 0.037
cellular lipid metabolic process GO:0044255 208 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
embryo development ending in birth or egg hatching GO:0009792 22 0.036
regulation of organelle organization GO:0033043 80 0.035
positive regulation of cell communication GO:0010647 271 0.035
positive regulation of secretion GO:0051047 140 0.035
single organism catabolic process GO:0044712 283 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.035
reproductive process GO:0022414 372 0.035
tissue development GO:0009888 252 0.034
amine metabolic process GO:0009308 38 0.034
g protein coupled receptor signaling pathway GO:0007186 242 0.033
cellular response to lipid GO:0071396 201 0.033
catabolic process GO:0009056 351 0.032
positive regulation of cell death GO:0010942 184 0.032
cell cell signaling involved in cell fate commitment GO:0045168 2 0.032
biological adhesion GO:0022610 110 0.032
single organismal cell cell adhesion GO:0016337 42 0.032
purine ribonucleotide metabolic process GO:0009150 227 0.031
neuron projection morphogenesis GO:0048812 122 0.031
lipoxygenase pathway GO:0019372 6 0.031
ribose phosphate metabolic process GO:0019693 235 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
ribonucleotide metabolic process GO:0009259 231 0.029
second messenger mediated signaling GO:0019932 51 0.029
positive regulation of programmed cell death GO:0043068 157 0.029
microtubule organizing center organization GO:0031023 1 0.029
positive regulation of hydrolase activity GO:0051345 86 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
purine containing compound metabolic process GO:0072521 253 0.028
regulation of membrane potential GO:0042391 110 0.028
purine nucleotide catabolic process GO:0006195 136 0.028
regulation of cell development GO:0060284 263 0.028
anion transmembrane transport GO:0098656 77 0.027
ossification GO:0001503 70 0.027
anion transport GO:0006820 178 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
response to extracellular stimulus GO:0009991 380 0.027
regulation of cell projection organization GO:0031344 175 0.027
positive regulation of cell proliferation GO:0008284 249 0.026
regulation of phosphorylation GO:0042325 248 0.026
cellular component morphogenesis GO:0032989 155 0.026
hemopoiesis GO:0030097 34 0.026
transcription dna templated GO:0006351 377 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
regulation of cell proliferation GO:0042127 359 0.025
regulation of transcription dna templated GO:0006355 374 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
regulation of cell projection size GO:0032536 1 0.025
regulation of neuron differentiation GO:0045664 208 0.025
antibiotic transport GO:0042891 2 0.024
lipid biosynthetic process GO:0008610 128 0.024
multi organism reproductive process GO:0044703 262 0.024
cell adhesion GO:0007155 110 0.024
regulation of synaptic transmission GO:0050804 141 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
regulation of endothelial cell differentiation GO:0045601 4 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
response to oxygen levels GO:0070482 265 0.024
head development GO:0060322 247 0.023
regulation of nervous system development GO:0051960 264 0.023
positive regulation of signaling GO:0023056 270 0.023
positive regulation of transport GO:0051050 245 0.023
regulation of blood vessel size GO:0050880 89 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
rna biosynthetic process GO:0032774 380 0.022
response to wounding GO:0009611 254 0.022
cytoskeleton organization GO:0007010 111 0.022
rna metabolic process GO:0016070 406 0.022
anterior posterior pattern specification GO:0009952 1 0.022
regulation of anatomical structure size GO:0090066 135 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.021
regulation of programmed cell death GO:0043067 341 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
negative regulation of developmental process GO:0051093 125 0.021
organ regeneration GO:0031100 101 0.021
localization of cell GO:0051674 202 0.021
chemotaxis GO:0006935 66 0.021
positive regulation of gene expression GO:0010628 244 0.021
regulation of cellular component biogenesis GO:0044087 86 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
metal ion transport GO:0030001 289 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
regulation of apoptotic process GO:0042981 335 0.021
regulation of peptide transport GO:0090087 87 0.021
brain development GO:0007420 247 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
aromatic compound catabolic process GO:0019439 168 0.020
positive regulation of cellular component movement GO:0051272 102 0.019
embryonic axis specification GO:0000578 1 0.019
regulation of neurogenesis GO:0050767 247 0.019
neuronal action potential GO:0019228 35 0.019
sodium ion transport GO:0006814 82 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
negative regulation of cell death GO:0060548 229 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
regulation of cell morphogenesis GO:0022604 77 0.019
positive regulation of cellular component biogenesis GO:0044089 55 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
regulation of hydrolase activity GO:0051336 143 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.018
regulation of protein modification process GO:0031399 194 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
chemical homeostasis GO:0048878 292 0.018
metal ion homeostasis GO:0055065 186 0.018
vesicle mediated transport GO:0016192 181 0.018
biomineral tissue development GO:0031214 12 0.018
nucleoside metabolic process GO:0009116 179 0.018
secretion by cell GO:0032940 248 0.018
long chain fatty acid biosynthetic process GO:0042759 5 0.018
embryonic pattern specification GO:0009880 1 0.018
positive regulation of organelle organization GO:0010638 48 0.018
regulation of phagocytosis engulfment GO:0060099 4 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
regulation of catalytic activity GO:0050790 304 0.018
response to metal ion GO:0010038 253 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
regulation of cellular component size GO:0032535 51 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
apoptotic process GO:0006915 381 0.017
regulation of cysteine type endopeptidase activity GO:2000116 32 0.017
response to bacterium GO:0009617 200 0.017
spindle organization GO:0007051 2 0.017
cytokine production GO:0001816 61 0.017
response to lipopolysaccharide GO:0032496 191 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
cellular ion homeostasis GO:0006873 184 0.017
transmission of nerve impulse GO:0019226 42 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
positive regulation of erythrocyte aggregation GO:0034120 1 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
cellular homeostasis GO:0019725 252 0.016
axis specification GO:0009798 4 0.016
regulation of secretion GO:0051046 224 0.016
response to camp GO:0051591 91 0.016
negative regulation of skeletal muscle cell differentiation GO:2001015 1 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
calcium ion transmembrane transport GO:0070588 70 0.016
regulation of translation GO:0006417 27 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
regulation of blood circulation GO:1903522 110 0.016
cell morphogenesis GO:0000902 142 0.016
positive regulation of locomotion GO:0040017 102 0.016
purine ribonucleotide biosynthetic process GO:0009152 81 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
wound healing GO:0042060 122 0.016
regulation of homeostatic process GO:0032844 101 0.016
response to external biotic stimulus GO:0043207 221 0.016
positive regulation of synaptic transmission GO:0050806 62 0.015
regulation of embryonic development GO:0045995 2 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
regulation of transporter activity GO:0032409 50 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
response to hexose GO:0009746 144 0.015
reproduction GO:0000003 245 0.015
regulation of ion transport GO:0043269 245 0.015
single organism cell adhesion GO:0098602 46 0.015
potassium ion transport GO:0006813 97 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
cell cycle checkpoint GO:0000075 2 0.015
positive regulation of endothelial cell migration GO:0010595 4 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
regulation of peptide secretion GO:0002791 82 0.015
immune system process GO:0002376 204 0.015
phospholipid biosynthetic process GO:0008654 29 0.015
cytolysis GO:0019835 4 0.015
sexual reproduction GO:0019953 148 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
response to amino acid GO:0043200 75 0.015
organic acid biosynthetic process GO:0016053 83 0.015
cofactor metabolic process GO:0051186 95 0.015
icosanoid biosynthetic process GO:0046456 18 0.014
positive regulation of cell migration GO:0030335 96 0.014
cell part morphogenesis GO:0032990 123 0.014
centrosome organization GO:0051297 1 0.014
nucleic acid templated transcription GO:0097659 379 0.014
multicellular organismal signaling GO:0035637 44 0.014
heterocycle catabolic process GO:0046700 167 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of cell adhesion GO:0030155 52 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
endomembrane system organization GO:0010256 48 0.014
regulation of protein metabolic process GO:0051246 289 0.014
salivary gland morphogenesis GO:0007435 1 0.014
syncytium formation GO:0006949 4 0.014
response to hypoxia GO:0001666 231 0.014
organophosphate catabolic process GO:0046434 148 0.014
cellular response to metal ion GO:0071248 55 0.014
ion homeostasis GO:0050801 212 0.014
amide transport GO:0042886 105 0.014
cellular macromolecular complex assembly GO:0034622 58 0.013
single organism behavior GO:0044708 130 0.013
single organism reproductive process GO:0044702 297 0.013
peptide secretion GO:0002790 86 0.013
neuron projection development GO:0031175 273 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
toxin transport GO:1901998 3 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
gamete generation GO:0007276 124 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
locomotion GO:0040011 237 0.013
response to purine containing compound GO:0014074 126 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
cellular response to fluid shear stress GO:0071498 4 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
organic substance catabolic process GO:1901575 316 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
regulation of cell migration GO:0030334 128 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
multicellular organism reproduction GO:0032504 233 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
eye morphogenesis GO:0048592 4 0.013
response to cold GO:0009409 29 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
action potential GO:0001508 54 0.013
regulation of response to wounding GO:1903034 69 0.013
lipid transport GO:0006869 61 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
cell migration GO:0016477 197 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.012
cation transport GO:0006812 382 0.012
cellular ketone metabolic process GO:0042180 51 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
behavior GO:0007610 205 0.012
regulation of hormone secretion GO:0046883 106 0.012
cell substrate adhesion GO:0031589 29 0.012
aging GO:0007568 241 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
positive regulation of signal transduction GO:0009967 175 0.012
positive regulation of cell motility GO:2000147 97 0.012
response to organophosphorus GO:0046683 102 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
organic anion transport GO:0015711 132 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
regulation of secretion by cell GO:1903530 208 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
peptide transport GO:0015833 97 0.012
response to estradiol GO:0032355 164 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
activation of cysteine type endopeptidase activity GO:0097202 4 0.012
cellular macromolecule localization GO:0070727 122 0.012
proteolysis GO:0006508 175 0.012
regulation of camp metabolic process GO:0030814 43 0.012
regulation of immune system process GO:0002682 123 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of locomotion GO:0040012 148 0.012
glycerophospholipid biosynthetic process GO:0046474 22 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
single organism biosynthetic process GO:0044711 342 0.011
rna localization GO:0006403 4 0.011
insulin secretion GO:0030073 69 0.011
response to other organism GO:0051707 220 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
cellular chemical homeostasis GO:0055082 247 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
in utero embryonic development GO:0001701 14 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of cellular component movement GO:0051270 150 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
positive regulation of cytoskeleton organization GO:0051495 26 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
negative regulation of cell development GO:0010721 82 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
membrane organization GO:0061024 94 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
regulation of endocytosis GO:0030100 42 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
rho protein signal transduction GO:0007266 11 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
lipid metabolic process GO:0006629 283 0.011
glycerolipid metabolic process GO:0046486 67 0.011
positive regulation of endothelial cell differentiation GO:0045603 2 0.011
negative regulation of cell differentiation GO:0045596 99 0.010
microtubule based process GO:0007017 36 0.010
feeding behavior GO:0007631 53 0.010
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
ras protein signal transduction GO:0007265 29 0.010
defecation GO:0030421 1 0.010
gonad development GO:0008406 104 0.010
taxis GO:0042330 67 0.010
actin cytoskeleton organization GO:0030036 73 0.010
male gamete generation GO:0048232 99 0.010
regulation of heterotypic cell cell adhesion GO:0034114 2 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
regulation of response to external stimulus GO:0032101 106 0.010
negative regulation of transport GO:0051051 136 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
vascular process in circulatory system GO:0003018 96 0.010
regulation of mrna stability GO:0043488 3 0.010
regulation of immune response GO:0050776 55 0.010
regulation of insulin secretion GO:0050796 65 0.010
inflammatory response GO:0006954 150 0.010
protein homooligomerization GO:0051260 91 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010

Alas2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024