IMP

Process View

Rattus norvegicus

4 genes annotated in rat

regulation of phagocytosis engulfment

Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of phagocytosis engulfment"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of phagocytosis engulfment" (in gray)

Name	Description	Probability	Func Analog Organism
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.533
Mef2d	myocyte enhancer factor 2D	0.418
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.356	Rat
Gja5	gap junction protein, alpha 5	0.272
Ptafr	platelet-activating factor receptor	0.251
Fgf1	fibroblast growth factor 1	0.250
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.175
Ptprh	protein tyrosine phosphatase, receptor type, H	0.169
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.155
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.150
Gata6	GATA binding protein 6	0.136
Gzmb	granzyme B	0.135
Prg2	proteoglycan 2, bone marrow	0.127
Ednra	endothelin receptor type A	0.119
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.118
Podxl	podocalyxin-like	0.094
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.092
Acot12	acyl-CoA thioesterase 12	0.088
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.081
Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8	0.079
Aqp7	aquaporin 7	0.078
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.072
Pdk4	pyruvate dehydrogenase kinase, isozyme 4	0.071
Rdh2	retinol dehydrogenase 2	0.070
Ccl5	chemokine (C-C motif) ligand 5	0.070
Lpl	lipoprotein lipase	0.070
Trib1	tribbles homolog 1 (Drosophila)	0.069
Il1r1	interleukin 1 receptor, type I	0.069
Mrgprf	MAS-related GPR, member F	0.068
Nkg7	natural killer cell group 7 sequence	0.067
Cidea	cell death-inducing DFFA-like effector a	0.065
Prdm2	PR domain containing 2, with ZNF domain	0.063
Runx3	runt-related transcription factor 3	0.063
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.061
Gpr4	G protein-coupled receptor 4	0.061
Dhdpsl	dihydrodipicolinate synthase-like, mitochondrial	0.061
Sgk2	serum/glucocorticoid regulated kinase 2	0.060
Mettl7b	methyltransferase like 7B	0.058
Zbp1	Z-DNA binding protein 1	0.057
Il1a	interleukin 1 alpha	0.052
Smad6	SMAD family member 6	0.052
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.052
Hmha1	histocompatibility (minor) HA-1	0.052
Ddc	dopa decarboxylase (aromatic L-amino acid decarboxylase)	0.050
Cd8b	CD8b molecule	0.049
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.048
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.048
Fli1	Friend leukemia virus integration 1	0.048
Efnb1	ephrin B1	0.048
Cpt1b	carnitine palmitoyltransferase 1b, muscle	0.047
Cybb	cytochrome b-245, beta polypeptide	0.047
Gcgr	glucagon receptor	0.047
Casq2	calsequestrin 2 (cardiac muscle)	0.046
P2ry4	pyrimidinergic receptor P2Y, G-protein coupled, 4	0.046
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.046
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.046
Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.043
Adra2b	adrenergic, alpha-2B-, receptor	0.042
Lypd3	Ly6/Plaur domain containing 3	0.040
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.039
Asb2	ankyrin repeat and SOCS box-containing 2	0.039
Crybb1	crystallin, beta B1	0.039
Ros1	c-ros oncogene 1 , receptor tyrosine kinase	0.038
Gckr	glucokinase (hexokinase 4) regulator	0.036
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.035
Il2rb	interleukin 2 receptor, beta	0.035
Capn9	calpain 9	0.035
Hnf4a	hepatocyte nuclear factor 4, alpha	0.035
Gip	gastric inhibitory polypeptide	0.034
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.034
LOC679368	similar to carboxylesterase 5	0.034
Icam2	intercellular adhesion molecule 2	0.033
Ly6g6e	lymphocyte antigen 6 complex, locus G6E	0.033
Fcer2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.032
RGD1561143	similar to cell surface receptor FDFACT	0.032
Scn5a	sodium channel, voltage-gated, type V, alpha subunit	0.031
Abcd1	ATP-binding cassette, subfamily D (ALD), member 1	0.031
Triobp	TRIO and F-actin binding protein	0.030
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.030
Acsl1	acyl-CoA synthetase long-chain family member 1	0.030
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.029
Cdh17	cadherin 17	0.029
Psgb1	pregnancy-specific beta 1-glycoprotein	0.029
Pdp2	pyruvate dehyrogenase phosphatase catalytic subunit 2	0.028
Galnt10	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)	0.028
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.028
Defb1	defensin beta 1	0.028
Slc5a1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.026
Cps1	carbamoyl-phosphate synthetase 1	0.026
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.026
Elf1	E74-like factor 1	0.026
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.025
Mlxipl	MLX interacting protein-like	0.025
Epha2	Eph receptor A2	0.025
Clcn5	chloride channel 5	0.024
Prss8	protease, serine, 8	0.024
Foxe1	forkhead box E1 (thyroid transcription factor 2)	0.024
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.024
Fzd4	frizzled homolog 4 (Drosophila)	0.024
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.024
Sptbn1	spectrin, beta, non-erythrocytic 1	0.024
Nrp1	neuropilin 1	0.024
Ly6al	lymphocyte antigen 6 complex, locus A-like	0.024
Acacb	acetyl-Coenzyme A carboxylase beta	0.023
Sox7	SRY (sex determining region Y)-box 7	0.023
Naaladl1	N-acetylated alpha-linked acidic dipeptidase-like 1	0.023
Cish	cytokine inducible SH2-containing protein	0.023
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.023
Prf1	perforin 1 (pore forming protein)	0.023
Ralgds	ral guanine nucleotide dissociation stimulator	0.023
Mocs1	molybdenum cofactor synthesis 1	0.022
Actc1	actin, alpha, cardiac muscle 1	0.022
S1pr2	sphingosine-1-phosphate receptor 2	0.022
Wt1	Wilms tumor 1	0.022
Nmu	neuromedin U	0.022
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.022	Rat
Bmp2	bone morphogenetic protein 2	0.021
F2rl1	coagulation factor II (thrombin) receptor-like 1	0.021	Human
Lect1	leukocyte cell derived chemotaxin 1	0.021
C5ar1	complement component 5a receptor 1	0.021
Icos	inducible T-cell co-stimulator	0.021
Adamtsl4	ADAMTS-like 4	0.021
Ncf1	neutrophil cytosolic factor 1	0.021
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.021
Gypc	glycophorin C (Gerbich blood group)	0.021
Nppb	natriuretic peptide precursor B	0.021
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.020
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.020
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.020
Arid3b	AT rich interactive domain 3B (Bright like)	0.020
Pric285	peroxisomal proliferator-activated receptor A interacting complex 285	0.020
Cfp	complement factor properdin	0.020
Lims2	LIM and senescent cell antigen like domains 2	0.020
Insr	insulin receptor	0.020
Gpr116	G protein-coupled receptor 116	0.020
Pou3f2	POU class 3 homeobox 2	0.020
Pld1	phospholipase D1	0.019
Utrn	utrophin	0.019
Neurl3	neuralized homolog 3 (Drosophila)	0.019
Sox13	SRY (sex determining region Y)-box 13	0.019
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.019
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.019
Sox17	SRY (sex determining region Y)-box 17	0.019
Grk4	G protein-coupled receptor kinase 4	0.019
RGD1306750	LOC362451	0.019
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.019
Hand2	heart and neural crest derivatives expressed 2	0.018
Prap1	proline-rich acidic protein 1	0.018
Hnf1b	HNF1 homeobox B	0.018
Rbp7	retinol binding protein 7, cellular	0.018
Olr837	olfactory receptor 837	0.018
Dnase1	deoxyribonuclease I	0.018
Rpl3l	ribosomal protein L3-like	0.018
Emid1	EMI domain containing 1	0.018
Alas2	aminolevulinate, delta-, synthase 2	0.018
A1cf	APOBEC1 complementation factor	0.018
Aldob	aldolase B, fructose-bisphosphate	0.018
Itgb7	integrin, beta 7	0.018
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.018
Mocos	molybdenum cofactor sulfurase	0.018
Gpr182	G protein-coupled receptor 182	0.017
Itgb2	integrin, beta 2	0.017
Cldn7	claudin 7	0.017
Gse1	genetic suppressor element 1	0.017
Hamp	hepcidin antimicrobial peptide	0.017
Serpinb5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.017
Ush1c	Usher syndrome 1C homolog (human)	0.017
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.017
Lrrc33	leucine rich repeat containing 33	0.017
Hic1	hypermethylated in cancer 1	0.017
Gimap4	GTPase, IMAP family member 4	0.017
Cxcr4	chemokine (C-X-C motif) receptor 4	0.016
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.016
RGD1304644	similar to RIKEN cDNA 2310046K01	0.016
Fabp4	fatty acid binding protein 4, adipocyte	0.016
LOC100364500	RT1 class I, locus CE11-like	0.016
Cd200r1	CD200 receptor 1	0.016
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.016
Prlr	prolactin receptor	0.016
Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.016
Cds2	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	0.016
LOC680711	hypothetical protein LOC680711	0.016
Cdh16	cadherin 16	0.015
Csn1s1	casein alpha s1	0.015
Edn1	endothelin 1	0.015
Insl3	insulin-like 3	0.015
Dnase1l3	deoxyribonuclease 1-like 3	0.015
Tgfbr2	transforming growth factor, beta receptor II	0.015
Gata5	GATA binding protein 5	0.015	Rat
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.015
Hr	hairless	0.015
Ghrhr	growth hormone releasing hormone receptor	0.015
LOC100360169	rCG21044-like	0.015
Ccr3	chemokine (C-C motif) receptor 3	0.015
RGD1564327	similar to integrin alpha 8	0.015	Rat
Gata4	GATA binding protein 4	0.015	Rat
Rara	retinoic acid receptor, alpha	0.015
Art2	ADP-ribosyltransferase 2	0.014
Gck	glucokinase	0.014
Ppara	peroxisome proliferator activated receptor alpha	0.014	Rat
Cda	cytidine deaminase	0.014
Plcg2	phospholipase C, gamma 2	0.014
Gna11	guanine nucleotide binding protein, alpha 11	0.014
Dao	D-amino-acid oxidase	0.014
Cpd	carboxypeptidase D	0.014
Ehd4	EH-domain containing 4	0.014
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.014
Lnpep	leucyl/cystinyl aminopeptidase	0.014
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.014
Dock8	dedicator of cytokinesis 8	0.014
Tbxa2r	thromboxane A2 receptor	0.014
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.014
Irs3	insulin receptor substrate 3	0.014
RT1-M5	RT1 class Ib, locus M5	0.014
Flt1	FMS-related tyrosine kinase 1	0.014
Itga2b	integrin, alpha 2B	0.014	Rat
Serpina3m	serine (or cysteine) proteinase inhibitor, clade A, member 3M	0.014
Foxo1	forkhead box O1	0.014
Lgals4	lectin, galactoside-binding, soluble, 4	0.014
Nrg1	neuregulin 1	0.014
Tead3	TEA domain family member 3	0.013
Abp10	annexin V-binding protein ABP-10	0.013
Pnpla2	patatin-like phospholipase domain containing 2	0.013
Cd4	Cd4 molecule	0.013
Hk2	hexokinase 2	0.013
Dysf	dysferlin	0.013
Mtus1	mitochondrial tumor suppressor 1	0.013
Tcf21	transcription factor 21	0.013
Adra1b	adrenergic, alpha-1B-, receptor	0.013
Hrg	histidine-rich glycoprotein	0.013
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.013
Rbm38	RNA binding motif protein 38	0.013
Tpo	thyroid peroxidase	0.012
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.012
Aoc3	amine oxidase, copper containing 3 (vascular adhesion protein 1)	0.012
Nos3	nitric oxide synthase 3, endothelial cell	0.012
Thbs2	thrombospondin 2	0.012
Cd52	CD52 antigen	0.012
Enpep	glutamyl aminopeptidase	0.012
Tal1	T-cell acute lymphocytic leukemia 1	0.012
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.012
Pla2g5	phospholipase A2, group V	0.012
Itga7	integrin, alpha 7	0.012	Rat
Acot2	acyl-CoA thioesterase 2	0.012
Akr1cl1	aldo-keto reductase family 1, member C-like 1	0.012
Dcaf17	DDB1 and CUL4 associated factor 17	0.012
Defa	defensin, alpha 5, Paneth cell-specific	0.012
Uox	urate oxidase	0.012
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.012
Pzp	pregnancy-zone protein	0.012
Prkd2	protein kinase D2	0.012
Syk	spleen tyrosine kinase	0.012
Epas1	endothelial PAS domain protein 1	0.012
Bche	butyrylcholinesterase	0.012
Pkhd1l1	polycystic kidney and hepatic disease 1-like 1	0.012
Tshr	thyroid stimulating hormone receptor	0.012
Ntn1	netrin 1	0.012
Coro6	coronin 6	0.012
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.011
LOC100360205	palladin	0.011
Aqp8	aquaporin 8	0.011
RGD1565512	similar to hypothetical protein 4932418E24	0.011
Npr2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)	0.011
Hfe2	hemochromatosis type 2 (juvenile) homolog (human)	0.011
Runx2	runt-related transcription factor 2	0.011
Csn1s2a	casein alpha s2-like A	0.011
Cga	glycoprotein hormones, alpha polypeptide	0.011
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.011
Ednrb	endothelin receptor type B	0.011
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.011
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.011
Tmem45b	transmembrane protein 45b	0.011
Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	0.011
Sost	sclerosteosis	0.011
F13a1	coagulation factor XIII, A1 polypeptide	0.011
Ebf1	early B-cell factor 1	0.011
Selp	selectin P	0.011
Steap3	STEAP family member 3	0.011
Abcc9	ATP-binding cassette, subfamily C (CFTR/MRP), member 9	0.011
Atp6v0a2	ATPase, H+ transporting, lysosomal V0 subunit A2	0.011
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.011
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.011
Ccdc49	coiled-coil domain containing 49	0.011
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.011
Lipe	lipase, hormone sensitive	0.011
Gngt2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	0.011
RGD1561145	similar to novel protein	0.011
Unc5cl	unc-5 homolog C (C. elegans)-like	0.011
Pck1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.011
Khk	ketohexokinase	0.011
Pla2g2c	phospholipase A2, group IIC	0.010
Oas1b	2-5 oligoadenylate synthetase 1B	0.010
C1galt1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1	0.010
Hbb	hemoglobin, beta	0.010
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.010
Lck	lymphocyte-specific protein tyrosine kinase	0.010
RGD1311756	similar to hypothetical protein FLJ20950	0.010
Klre1	killer cell lectin-like receptor, family E, member 1	0.010
Mmrn1	multimerin 1	0.010
P2rx5	purinergic receptor P2X, ligand-gated ion channel, 5	0.010
Pear1	platelet endothelial aggregation receptor 1	0.010
Cblc	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.010
Acadm	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	0.010